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NO20084540L - Benzoimidazol-2-ylpyrimidiner og -pyraziner som modulatorer av histamin H4-reseptoren - Google Patents

Benzoimidazol-2-ylpyrimidiner og -pyraziner som modulatorer av histamin H4-reseptoren

Info

Publication number
NO20084540L
NO20084540L NO20084540A NO20084540A NO20084540L NO 20084540 L NO20084540 L NO 20084540L NO 20084540 A NO20084540 A NO 20084540A NO 20084540 A NO20084540 A NO 20084540A NO 20084540 L NO20084540 L NO 20084540L
Authority
NO
Norway
Prior art keywords
ylpyrimidines
benzoimidazol
pyrazines
receptor
histamine
Prior art date
Application number
NO20084540A
Other languages
English (en)
Other versions
NO341523B1 (no
Inventor
James P Edwards
David E Kindrachuk
Jennifer D Venable
Christopher M Mapes
Daniel J Pippel
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38581554&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20084540(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20084540L publication Critical patent/NO20084540L/no
Publication of NO341523B1 publication Critical patent/NO341523B1/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Immunology (AREA)
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  • Diabetes (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)

Abstract

Det beskrives benzoimidazol-2-ylpyrimidiner og -pyraziner. Det beskrives videre farmasøytiske preparater inneholdende disse. Videre beskrives fremgangsmåter for behandling av sykdomstilstander, forstyrrelser og forhold som er mediert av Hrreseptoraktivitet inkludert allergi, astma, autoimmune sykdommer og pruritt.
NO20084540A 2006-03-31 2008-10-28 Benzoimidazol-2-ylpyrimidiner og -pyraziner som modulatorer av histamin H4-reseptoren, farmasøytisk sammensetning samt anvendelse NO341523B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78819006P 2006-03-31 2006-03-31
PCT/US2007/008216 WO2007117399A2 (en) 2006-03-31 2007-03-30 Benzoimidazol-2-yl pyrimidines and pyrazines as modulators of the histamine h4 receptor

Publications (2)

Publication Number Publication Date
NO20084540L true NO20084540L (no) 2008-10-28
NO341523B1 NO341523B1 (no) 2017-11-27

Family

ID=38581554

Family Applications (1)

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NO20084540A NO341523B1 (no) 2006-03-31 2008-10-28 Benzoimidazol-2-ylpyrimidiner og -pyraziner som modulatorer av histamin H4-reseptoren, farmasøytisk sammensetning samt anvendelse

Country Status (34)

Country Link
US (6) US7507737B2 (no)
EP (1) EP2007752B1 (no)
JP (1) JP5066175B2 (no)
KR (1) KR101054325B1 (no)
CN (1) CN101460483B (no)
AR (1) AR059380A1 (no)
AT (1) ATE478067T1 (no)
AU (1) AU2007235576B2 (no)
BR (1) BRPI0710083A2 (no)
CA (1) CA2648036C (no)
CO (1) CO6160328A2 (no)
CR (1) CR10413A (no)
CY (1) CY1111169T1 (no)
DE (1) DE602007008545D1 (no)
DK (1) DK2007752T3 (no)
EA (1) EA016264B1 (no)
EC (1) ECSP088815A (no)
ES (1) ES2348829T3 (no)
IL (2) IL194453A0 (no)
ME (1) ME01143B (no)
MX (1) MX2008012655A (no)
NI (1) NI200800260A (no)
NO (1) NO341523B1 (no)
NZ (1) NZ571691A (no)
PE (1) PE20080130A1 (no)
PL (1) PL2007752T3 (no)
PT (1) PT2007752E (no)
RS (1) RS51423B (no)
SI (1) SI2007752T1 (no)
TW (1) TWI400234B (no)
UA (1) UA95949C2 (no)
UY (1) UY30253A1 (no)
WO (1) WO2007117399A2 (no)
ZA (1) ZA200809328B (no)

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JP2009532367A (ja) * 2006-03-31 2009-09-10 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒスタミンｈ４受容体のモジュレーターとしてのベンゾイミダゾール−２−イルピリジン
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