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NO20071294L - Apparat og fremgangsmate for transdermal levering av natriuretiske peptider. - Google Patents

Apparat og fremgangsmate for transdermal levering av natriuretiske peptider.

Info

Publication number
NO20071294L
NO20071294L NO20071294A NO20071294A NO20071294L NO 20071294 L NO20071294 L NO 20071294L NO 20071294 A NO20071294 A NO 20071294A NO 20071294 A NO20071294 A NO 20071294A NO 20071294 L NO20071294 L NO 20071294L
Authority
NO
Norway
Prior art keywords
natriuretic peptide
contained
transdermal delivery
natriuretic peptides
microprotection
Prior art date
Application number
NO20071294A
Other languages
English (en)
Inventor
Peter E Daddona
Yuh-Fun Maa
Marika Kamberi
Scott Sellers
Vidhya Gopalakrishnan
B Michael Silber
Frank Stonebanks
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of NO20071294L publication Critical patent/NO20071294L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En innretning og fremgangsmåte for transdermal avlevering av et natriuretisk peptid som omfatter et avleveringssystem som har et mikrofremspringselement som innbefatter et stort antall mikrofremspring (eller rekker derav) som er egnet til å gjennombore stratum corneum inn i det underliggende epidermislaget, eller epidermis og dermislagene. I en utførelsesform, inneholdes det natriuretiske peptidet i et biokompatibelt belegg som er påført mikrofremspringselementet. I ytterligere en utførelsesform, innbefatter avleveringssystemet en hydrogelformulering som inneholder et natriuretisk peptid. I en alternativ utførelsesform, inneholdes det natriuretiske peptidet både i belegget og hydrogelformuleringen. I ytterligere en annen utførelsesform, inneholdes det natriuretiske peptidet i en faststofformulering.
NO20071294A 2004-08-11 2007-03-09 Apparat og fremgangsmate for transdermal levering av natriuretiske peptider. NO20071294L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60056004P 2004-08-11 2004-08-11
PCT/US2005/028693 WO2006020841A2 (en) 2004-08-11 2005-08-10 Apparatus and method for transdermal delivery of natriuretic peptides

Publications (1)

Publication Number Publication Date
NO20071294L true NO20071294L (no) 2007-05-10

Family

ID=35466467

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071294A NO20071294L (no) 2004-08-11 2007-03-09 Apparat og fremgangsmate for transdermal levering av natriuretiske peptider.

Country Status (13)

Country Link
US (1) US20060034903A1 (no)
EP (1) EP1778203A2 (no)
JP (1) JP2008509746A (no)
KR (1) KR20070042573A (no)
CN (1) CN101232874A (no)
AR (1) AR050292A1 (no)
AU (1) AU2005272700A1 (no)
CA (1) CA2576852A1 (no)
IL (1) IL181268A0 (no)
MX (1) MX2007001667A (no)
NO (1) NO20071294L (no)
TW (1) TW200616660A (no)
WO (1) WO2006020841A2 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1697035B1 (en) * 2003-12-22 2017-11-15 Warren H. Finlay Powder formation by atmospheric spray-freeze drying
AU2007233123A1 (en) * 2006-03-30 2007-10-11 Palatin Technologies, Inc. Linear natriuretic peptide constructs
US8580746B2 (en) * 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
AU2007233116B2 (en) * 2006-03-30 2013-05-09 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
US20070249988A1 (en) * 2006-04-21 2007-10-25 Alza Corporation Electrotransport Delivery of Nesiritide
JP5066566B2 (ja) * 2006-07-03 2012-11-07 ホナム ペトロケミカル コープ マイクロニードルローラアセンブリ
WO2009086166A1 (en) * 2007-12-19 2009-07-09 Ekr Therapeutics, Inc. Room temperature stable, lyophilized natriuretic peptide formulations
WO2010087300A1 (ja) * 2009-01-30 2010-08-05 久光製薬株式会社 マイクロニードルデバイス
ES2456502T3 (es) * 2009-07-23 2014-04-22 Igisu Co., Ltd. Composición que comprende PNC o PNB para un preparado externo para la piel para el tratamiento de la dermatitis
NZ598600A (en) 2009-08-27 2014-03-28 Kyoko Endo Therapeutic agent for rhinitis
CN102770176B (zh) * 2010-02-24 2015-11-25 久光制药株式会社 微针装置及其制造方法
CN110801514A (zh) 2011-01-21 2020-02-18 Igisu株式会社 秃头症治疗剂
CN105025942B (zh) * 2012-12-07 2017-11-14 堪萨斯州立大学研究基金会 肽‑白蛋白水凝胶的性能及其应用
KR20180010267A (ko) 2015-05-29 2018-01-30 가부시키가이샤 이기스 환상 펩티드 및 그 환상 펩티드를 포함한 의약, 외용제 및 화장료

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
ATE234649T1 (de) * 1996-12-20 2003-04-15 Alza Corp Vorrichtung und verfahren zur erhöhung des transdermalen wirkstoffeflusses
US6211296B1 (en) * 1998-11-05 2001-04-03 The B. F. Goodrich Company Hydrogels containing substances
JP4237375B2 (ja) * 2000-03-31 2009-03-11 アスビオファーマ株式会社 虚血性疾患の処置又は予防に用いる医薬組成物
KR100764699B1 (ko) * 2000-09-08 2007-10-08 알자 코포레이션 경로 폐쇄 저해에 의한 경피 약물 플럭스 감소 저해방법
BRPI0412029A (pt) * 2003-06-30 2006-09-05 Alza Corp formulações para microprojeções revestidas contendo contra-ìons não-voláteis
AU2004255228A1 (en) * 2003-06-30 2005-01-20 Alza Corporation Method for coating skin piercing microprojections
US20050031676A1 (en) * 2003-08-04 2005-02-10 Wong Patrick S.L. Method and device for enhancing transdermal agent flux
ES2377647T3 (es) * 2003-10-31 2012-03-29 Alza Corporation Aplicador auto-actuado para ordenamiento de microproyecciones
MXPA06007832A (es) * 2004-01-09 2007-01-26 Johnson & Johnson Metodo y sistema de suministro de agente transdermico asistido por frecuencia.
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices

Also Published As

Publication number Publication date
CA2576852A1 (en) 2006-02-23
EP1778203A2 (en) 2007-05-02
JP2008509746A (ja) 2008-04-03
MX2007001667A (es) 2007-10-02
WO2006020841A2 (en) 2006-02-23
CN101232874A (zh) 2008-07-30
IL181268A0 (en) 2007-07-04
AR050292A1 (es) 2006-10-11
KR20070042573A (ko) 2007-04-23
US20060034903A1 (en) 2006-02-16
AU2005272700A1 (en) 2006-02-23
WO2006020841A3 (en) 2007-08-16
TW200616660A (en) 2006-06-01

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