NO20064186L - Substituerte pyrazolin sammensetninger for a redusere triglycerider i blod - Google Patents
Substituerte pyrazolin sammensetninger for a redusere triglycerider i blodInfo
- Publication number
- NO20064186L NO20064186L NO20064186A NO20064186A NO20064186L NO 20064186 L NO20064186 L NO 20064186L NO 20064186 A NO20064186 A NO 20064186A NO 20064186 A NO20064186 A NO 20064186A NO 20064186 L NO20064186 L NO 20064186L
- Authority
- NO
- Norway
- Prior art keywords
- compositions
- reduce blood
- substituted pyrazoline
- blood triglycerides
- substituted
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
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- Neurology (AREA)
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- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
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Abstract
Foreliggende oppfinnelse angår substituerte pyrazolin forbindelser, fremgangsmåte for deres fremstilling, medikamenter som omfatter disse forbindelsene så vel som deres anvendelse for fremstilling av et medikament for behandling av mennesker og dyr.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200400378 | 2004-02-17 | ||
US80453404A | 2004-03-19 | 2004-03-19 | |
EP04021974A EP1637522A1 (en) | 2004-09-16 | 2004-09-16 | Substituted pyrazoline compounds for reducing triglycerides in blood |
PCT/EP2005/001465 WO2005077909A1 (en) | 2004-02-17 | 2005-02-14 | Substituted pyrazoline compounds for reducing triglycerides in blood |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20064186L true NO20064186L (no) | 2006-11-14 |
Family
ID=34864786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20064186A NO20064186L (no) | 2004-02-17 | 2006-09-15 | Substituerte pyrazolin sammensetninger for a redusere triglycerider i blod |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1718619A1 (no) |
JP (1) | JP2007522252A (no) |
KR (1) | KR20060135815A (no) |
AU (1) | AU2005212817A1 (no) |
BR (1) | BRPI0507790A (no) |
CA (1) | CA2556568A1 (no) |
IL (1) | IL177454A0 (no) |
NO (1) | NO20064186L (no) |
RU (1) | RU2006133260A (no) |
WO (1) | WO2005077909A1 (no) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005044785A1 (en) | 2003-10-30 | 2005-05-19 | Merck & Co., Inc. | Aralkyl amines as cannabinoid receptor modulators |
TW200533657A (en) * | 2004-02-17 | 2005-10-16 | Esteve Labor Dr | Substituted pyrazoline compounds, their preparation and use as medicaments |
ES2326723B1 (es) * | 2005-07-15 | 2010-05-11 | Laboratorios Del Dr. Esteve, S.A. | Uso de compuestos de pirazol sustituidos y combinaciones de los mismos para el tratamiento del sindrome metabolico. |
WO2007009706A2 (en) * | 2005-07-15 | 2007-01-25 | Laboratorios Del Dr. Esteve, S.A. | Substituted pyrazoline compounds, having predetermined stereochemistry, for reducing triglycerides in blood |
ES2326725B1 (es) * | 2005-07-15 | 2010-05-11 | Laboratorios Del Dr. Esteve, S.A. | Uso de compuestos de pirazolina sustituidos para el tratamiento de trastornos alimentarios, que incluyen la obesidad o el sindrome metabolico en pacientes con diabetes desarrollada. |
WO2007009683A2 (en) * | 2005-07-15 | 2007-01-25 | Laboratorios Del Dr.Esteve, S.A. | Pharmaceutical formulations of substituted pyrazoline compounds |
ES2336883B1 (es) * | 2005-07-15 | 2011-03-22 | Laboratorios Del Dr. Esteve, S.A. | Compuestos de pirazolina sustituidos, con una estereoquimica predeterminada, para la reduccion de trigliceridos en sangre. |
EP1743637A1 (en) * | 2005-07-15 | 2007-01-17 | Laboratorios Del Dr. Esteve, S.A. | Use of substituted pyrazole compounds and combinations thereof for the treatment of the metabolic syndrome |
EP1743639A1 (en) * | 2005-07-15 | 2007-01-17 | Laboratorios Del Dr. Esteve, S.A. | Use of substituted pyrazoline compounds for the treatment of coagulation related diseases |
EP1745781A1 (en) * | 2005-07-15 | 2007-01-24 | Laboratorios Del Dr. Esteve, S.A. | Combination of pyrazoline type cannabinoid receptor antagonist and statin |
WO2007009698A1 (en) * | 2005-07-15 | 2007-01-25 | Laboratorios Del Dr. Esteve, S.A | Combination of pyrazoline type cannabinoid receptor antagonist and statin |
EP1749527A1 (en) * | 2005-07-15 | 2007-02-07 | Laboratorios Del Dr. Esteve, S.A. | Use of substituted pyrazoline compounds for the treatment of the lipid parameters of the metabolic syndrome |
EP1749526A1 (en) * | 2005-07-15 | 2007-02-07 | Laboratorios Del Dr. Esteve, S.A. | Use of substituted pyrazoline compounds for the treatment of food disorders, including obesity or metabolic syndrome in patients with developed diabetes |
ES2327203B1 (es) * | 2005-07-15 | 2010-06-07 | Laboratorios Del Dr. Esteve, S.A. | Uso de compuestos de pirazolina sustituidos para el tratamiento de trastornos relacionados con la coagulacion. |
ES2326857B1 (es) * | 2005-07-15 | 2010-05-11 | Laboratorios Del Dr. Esteve, S.A. | Uso de compuestos de pirazolina sustituidos para el tratamiento de los parametros lipidicos del sindrome metabolico. |
EP1743889A1 (en) * | 2005-07-15 | 2007-01-17 | Laboratorios del Dr. Esteve S.A. | Sustituted pyrazoline compounds, having predetermined stereochemistry, for reducing triglycerides in blood |
EP1746090A1 (en) * | 2005-07-15 | 2007-01-24 | Laboratorios del Dr. Esteve S.A. | Sustituted pyrazoline compounds, having predetermined stereochemistry, for reducing triglycerides in blood |
EP1944295A1 (en) * | 2007-01-15 | 2008-07-16 | Laboratorios del Dr. Esteve S.A. | Non-racemic mixtures of (R)-N-piperidinyl-5-(4-chlorophenyl)1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide and (S)-N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-3-carboxamide |
EP1944296A1 (en) * | 2007-01-15 | 2008-07-16 | Laboratorios del Dr. Esteve S.A. | Amorphous phase of a substituted pyrazoline, its preparation and use as medicaments |
EP1946779A1 (en) * | 2007-01-16 | 2008-07-23 | Laboratorios del Dr. Esteve S.A. | Combination of substituted pyrazolines and agent for treating dyslipidemia |
EP1947088A1 (en) * | 2007-01-17 | 2008-07-23 | Laboratorios del Dr. Esteve S.A. | Substituted pyrazoline compounds with ACAT inhibition activity, their preparation and use as medicaments |
EP1950203A1 (en) * | 2007-01-24 | 2008-07-30 | Laboratorios del Dr. Esteve S.A. | Substituted pyrazoline compounds with ACAT, their preparation and use as medicaments |
US20100099712A1 (en) * | 2007-01-17 | 2010-04-22 | Laboratorios Del Dr. Esteve, S.A. | Substituted pyrazoline compounds with acat inhibition activity |
EP2114892A1 (en) * | 2007-01-17 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | Substituted pyrazoline compounds with acat inhibition activity, their preparation and use as medicaments |
KR101395658B1 (ko) | 2012-09-20 | 2014-05-16 | 서울대학교산학협력단 | 4-(5-(2-메톡시페닐)-3-(p-톨릴)-4,5-디하이드로-1H-피라졸-1-일)-4-옥소부탄산을 포함하는 골대사성 질환의 예방 및 치료용 조성물 |
KR101466377B1 (ko) * | 2012-10-22 | 2014-12-01 | 건국대학교 산학협력단 | 디메톡시페닐디히드로피라졸릴나프탈레놀 유도체 및 그 제법 및 항암제로서의 용도 |
DK2920165T3 (en) * | 2012-11-16 | 2017-01-16 | Bristol Myers Squibb Co | Dihydropyrazol-GPR40-MODULATORS |
CA2891551A1 (en) * | 2012-11-16 | 2014-05-22 | Bristol-Myers Squibb Company | Dihydropyrazole gpr40 modulators |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1053661B (it) * | 1966-09-27 | 1981-10-10 | Farmacosmici S P A | Ammidi dell acido 3 5 metil 5 3 pirazol carbossilico |
JPH01502513A (ja) * | 1987-01-05 | 1989-08-31 | イー・アイ・デユポン・デ・ニモアス・アンド・カンパニー | 殺昆虫性ピラゾリン類 |
ES2174757B1 (es) * | 2001-04-06 | 2003-11-01 | Esteve Labor Dr | Empleo de derivados de firazolinas en la elaboracion de un medicamentopara la prevencion y/o el tratamiento de enfermedades proliferativas celulares. |
-
2005
- 2005-02-14 CA CA002556568A patent/CA2556568A1/en not_active Abandoned
- 2005-02-14 RU RU2006133260/04A patent/RU2006133260A/ru not_active Application Discontinuation
- 2005-02-14 AU AU2005212817A patent/AU2005212817A1/en not_active Abandoned
- 2005-02-14 BR BRPI0507790-7A patent/BRPI0507790A/pt not_active IP Right Cessation
- 2005-02-14 KR KR1020067018876A patent/KR20060135815A/ko not_active Application Discontinuation
- 2005-02-14 WO PCT/EP2005/001465 patent/WO2005077909A1/en active Application Filing
- 2005-02-14 JP JP2006553505A patent/JP2007522252A/ja active Pending
- 2005-02-14 EP EP05715327A patent/EP1718619A1/en not_active Withdrawn
-
2006
- 2006-08-10 IL IL177454A patent/IL177454A0/en unknown
- 2006-09-15 NO NO20064186A patent/NO20064186L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL177454A0 (en) | 2006-12-10 |
CA2556568A1 (en) | 2005-08-25 |
WO2005077909A1 (en) | 2005-08-25 |
RU2006133260A (ru) | 2008-04-10 |
BRPI0507790A (pt) | 2007-07-17 |
AU2005212817A1 (en) | 2005-08-25 |
KR20060135815A (ko) | 2006-12-29 |
EP1718619A1 (en) | 2006-11-08 |
JP2007522252A (ja) | 2007-08-09 |
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