NO20055253L - Behandling av autoimmun sykdom i en pasient med utilstrekkelig respons pa en TNF-alfa-inhibitor - Google Patents
Behandling av autoimmun sykdom i en pasient med utilstrekkelig respons pa en TNF-alfa-inhibitorInfo
- Publication number
- NO20055253L NO20055253L NO20055253A NO20055253A NO20055253L NO 20055253 L NO20055253 L NO 20055253L NO 20055253 A NO20055253 A NO 20055253A NO 20055253 A NO20055253 A NO 20055253A NO 20055253 L NO20055253 L NO 20055253L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- autoimmune disease
- tnf
- patient
- alpha inhibitor
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 2
- 229940046728 tumor necrosis factor alpha inhibitor Drugs 0.000 title abstract 2
- 239000002452 tumor necrosis factor alpha inhibitor Substances 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 abstract 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
Abstract
2005 8 174007-EOH Sammendrag Foreliggende patentsøknad beskriver behandling med antagonister som bindes til Bcelleoverflatemarkører, for eksempel CD20. Nærmere bestemt beskriver patentsøknaden anvendelse av slike antagonister for behandling av autoimmun sykdom i et pattedyr som opplever en utilstrekkelig respons på en TNFa-inhibitor.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46148103P | 2003-04-09 | 2003-04-09 | |
PCT/US2004/010509 WO2004091657A2 (en) | 2003-04-09 | 2004-04-06 | Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20055253L true NO20055253L (no) | 2005-11-08 |
Family
ID=33299824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20055253A NO20055253L (no) | 2003-04-09 | 2005-11-08 | Behandling av autoimmun sykdom i en pasient med utilstrekkelig respons pa en TNF-alfa-inhibitor |
Country Status (31)
Country | Link |
---|---|
US (4) | US20040202658A1 (no) |
EP (2) | EP1613350B1 (no) |
JP (3) | JP2006522811A (no) |
KR (2) | KR101092171B1 (no) |
CN (2) | CN1802176A (no) |
AT (1) | ATE425766T1 (no) |
AU (1) | AU2004229376B2 (no) |
BR (1) | BRPI0409534A (no) |
CA (1) | CA2519870A1 (no) |
CR (1) | CR8033A (no) |
CY (1) | CY1109127T1 (no) |
DE (1) | DE602004020061D1 (no) |
DK (1) | DK1613350T3 (no) |
EC (1) | ECSP056082A (no) |
ES (1) | ES2322267T3 (no) |
HR (2) | HRP20050940A2 (no) |
IL (2) | IL171038A (no) |
MA (1) | MA27838A1 (no) |
ME (1) | ME00426B (no) |
MX (1) | MXPA05010778A (no) |
NO (1) | NO20055253L (no) |
NZ (2) | NZ587776A (no) |
PL (1) | PL1613350T3 (no) |
PT (1) | PT1613350E (no) |
RS (1) | RS51686B (no) |
RU (1) | RU2358762C9 (no) |
SI (1) | SI1613350T1 (no) |
TN (1) | TNSN05234A1 (no) |
UA (2) | UA91961C2 (no) |
WO (1) | WO2004091657A2 (no) |
ZA (1) | ZA200507805B (no) |
Families Citing this family (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000067796A1 (en) | 1999-05-07 | 2000-11-16 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to b cell surface markers |
KR20080075044A (ko) * | 1999-07-12 | 2008-08-13 | 제넨테크, 인크. | Cd20에 결합하는 길항제를 사용한 외래 항원에 대한 면역반응 차단 방법 |
ATE482719T1 (de) | 2002-02-21 | 2010-10-15 | Univ Duke | Behandlungsverfahren unter verwendung von anti- cd22-antikörpern |
US20090217404A1 (en) * | 2002-09-27 | 2009-08-27 | Lowe Scott W | Cell-based RNA interference and related methods and compositions |
ATE470675T1 (de) * | 2002-12-16 | 2010-06-15 | Genentech Inc | Immunoglobulinvarianten und deren verwendungen |
US20090186839A1 (en) * | 2003-02-17 | 2009-07-23 | Cold Spring Harbor Laboratory | Model for studying the role of genes in chemoresistance |
DK1599573T3 (da) * | 2003-02-17 | 2013-07-08 | Cold Spring Harbor Lab | Model til at studere genernes rolle i tumorresistens over for kemoterapi |
EP1460088A1 (en) * | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
DK1613350T3 (da) | 2003-04-09 | 2009-06-22 | Genentech Inc | Behandling af autoimmun sygdom hos en patient med et utilstrækkeligt respons på en TNF-alfa-inhibitor |
EP2960251A1 (en) * | 2003-05-09 | 2015-12-30 | Duke University | CD20-specific antibodies and methods of employing same |
AR044388A1 (es) * | 2003-05-20 | 2005-09-07 | Applied Molecular Evolution | Moleculas de union a cd20 |
US20050053602A1 (en) * | 2003-08-29 | 2005-03-10 | Genentech, Inc. | Therapy of ocular disorders |
UA91823C2 (ru) | 2003-11-05 | 2010-09-10 | Гликарт Биотехнолоджи Аг | Гуманизированная анти-cd20 антигенсвязующая молекула ии типа, которая специфически связывается с cd20 человека |
US20060002930A1 (en) * | 2004-04-16 | 2006-01-05 | Genentech, Inc. | Treatment of disorders |
JP2008501712A (ja) | 2004-06-04 | 2008-01-24 | ジェネンテック・インコーポレーテッド | 多発性硬化症を処置するための方法 |
DOP2005000108A (es) * | 2004-06-04 | 2007-06-15 | Genentech Inc | Method for treating lupus |
AU2005267028A1 (en) * | 2004-07-22 | 2006-02-02 | Genentech, Inc. | Method of treating Sjogren's syndrome |
BR122018016031B8 (pt) | 2004-08-04 | 2021-07-27 | Applied Molecular Evolution Inc | processo para produzir um anticorpo monoclonal variante com resposta de adcc realçada |
US20060110387A1 (en) * | 2004-10-05 | 2006-05-25 | Genentech, Inc. | Method for treating vasculitis |
US8137907B2 (en) * | 2005-01-03 | 2012-03-20 | Cold Spring Harbor Laboratory | Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof |
AU2006204757A1 (en) * | 2005-01-13 | 2006-07-20 | Genentech, Inc. | Treatment method |
US20060263357A1 (en) * | 2005-05-05 | 2006-11-23 | Tedder Thomas F | Anti-CD19 antibody therapy for autoimmune disease |
EP2548575A1 (en) * | 2005-02-15 | 2013-01-23 | Duke University | Anti-CD19 antibodies that mediate ADCC for use in treating autoimmune diseases |
US8444973B2 (en) * | 2005-02-15 | 2013-05-21 | Duke University | Anti-CD19 antibodies and uses in B cell disorders |
PL2567976T3 (pl) * | 2005-03-23 | 2018-01-31 | Genmab As | Przeciwciała przeciw-cd38 przeznaczone do leczenia szpiczaka mnogiego |
AR053579A1 (es) * | 2005-04-15 | 2007-05-09 | Genentech Inc | Tratamiento de la enfermedad inflamatoria intestinal (eii) |
ES2341484T3 (es) | 2005-05-20 | 2010-06-21 | Genentech, Inc. | Pretratamiento de una muestra biologica de un sujeto que sufre una enfermedad autoinmune. |
US20070044164A1 (en) * | 2005-05-31 | 2007-02-22 | Cold Spring Harbor Laboratory | Methods for producing microRNAs |
EP1904101A4 (en) * | 2005-06-08 | 2011-06-15 | Univ Duke | ANTI-CD19 ANTIBODY THERAPY FOR TRANSPLANTATION |
MX2008000985A (es) * | 2005-07-21 | 2008-04-07 | Abbott Lab | Expresion de gen multiple que incluye construcciones y metodos sorf (cuadro de lectura abierta simple) con poliproteinas, pro-proteinas y proteolisis. |
CA2627891A1 (en) * | 2005-11-01 | 2007-05-10 | Novartis Ag | Uses of anti-cd40 antibodies |
US8470318B2 (en) * | 2005-11-07 | 2013-06-25 | The Rockefeller University | Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods |
MY149159A (en) * | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
EP2540741A1 (en) | 2006-03-06 | 2013-01-02 | Aeres Biomedical Limited | Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
AU2007223903B2 (en) * | 2006-03-06 | 2013-09-05 | Medimmune, Llc | Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
CN101432301B (zh) * | 2006-04-05 | 2014-01-08 | 洛克菲勒大学 | 具有增强的抗炎性和降低的细胞毒性特性的多肽以及相关方法 |
BRPI0711011A2 (pt) | 2006-05-18 | 2011-08-23 | Molecular Profiling Inst Inc | método para a determinação da intervenção médica para um estado de doença, método para a identificação de uma terapia de droga com capacidade de interação com um alvo molecular e sistema para a determinação da intervenção médica individualizada para um estado de doença |
US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
WO2008031056A2 (en) | 2006-09-08 | 2008-03-13 | Medimmune, Llc | Humanized anti-cd19 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
US8420330B2 (en) * | 2011-07-15 | 2013-04-16 | Myra A. Lipes | Diagnosis and treatment of cardiac troponin 1 (cTn1) autoantibody-mediated heart disease |
GB0707208D0 (en) * | 2007-04-13 | 2007-05-23 | Istituto Superiore Di Sanito | Novel disease treatments |
JP5424330B2 (ja) * | 2007-07-26 | 2014-02-26 | 国立大学法人大阪大学 | インターロイキン6受容体阻害剤を有効成分とする眼炎症疾患治療剤 |
PT2211904T (pt) * | 2007-10-19 | 2016-11-02 | Seattle Genetics Inc | Agentes de ligação a cd19 e seus usos |
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