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NO20045540L - Nye 3-(4-okso-4H-kromen-2-yl)-(1H)-kinolin-4-on-forbindelser, en fremgangsmate for deres fremstilling og farmasoytisk sammensetninger inneholdende dem - Google Patents

Nye 3-(4-okso-4H-kromen-2-yl)-(1H)-kinolin-4-on-forbindelser, en fremgangsmate for deres fremstilling og farmasoytisk sammensetninger inneholdende dem

Info

Publication number
NO20045540L
NO20045540L NO20045540A NO20045540A NO20045540L NO 20045540 L NO20045540 L NO 20045540L NO 20045540 A NO20045540 A NO 20045540A NO 20045540 A NO20045540 A NO 20045540A NO 20045540 L NO20045540 L NO 20045540L
Authority
NO
Norway
Prior art keywords
chromene
quinolin
oxo
compounds
preparation
Prior art date
Application number
NO20045540A
Other languages
English (en)
Other versions
NO331618B1 (no
Inventor
Jean-Daniel Brion
Catherine Harpey
Alain Le Ridant
Lucien Israel
Cherif Rabhi
El Bachir Kaloun
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20045540L publication Critical patent/NO20045540L/no
Publication of NO331618B1 publication Critical patent/NO331618B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Forbindelse med formel (I): hvori: ¿ R1, R2, R3, R4, R6, R8, R9 og R10, som kan være de samme eller forskjellige, hver representerer en gruppe valgt fra hydrogen, hydroksy, alkoksy, alkyl, arylalkoksy, alkoksykarbonylalkoksy og OR' hvori R' representerer en ionisert eller ioniserbar gruppe, ¿ R5 representerer en gruppe valgt fra alkyl, aryl og heteroaryl, ¿ R7 representerer en gruppe valgt fra hydrogen, hydroksy, alkoksy, alkyl og cykloalkyl, eller R7 representerer en nitrogeninneholdende eller oksygeninneholdende heterocykel, optiske isomerer derav når de forekommer, hydrater og solvater derav og addisjonssalter derav med en farmasøytisk akseptabel syre. Medikamenter.
NO20045540A 2002-06-19 2004-12-17 Nye 3-(4-okso-4H-kromen-2-yl)-(1H)-kinolin-4-on-forbindelser, en fremgangsmate for deres fremstilling og farmasoytisk sammensetninger inneholdende dem NO331618B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0207536A FR2841243B1 (fr) 2002-06-19 2002-06-19 Nouveaux derives de 3-(4-oxo-4h-chromen-2yl)-(1h)-quinolein- 4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2003/001849 WO2004000834A1 (fr) 2002-06-19 2003-06-18 Nouveaux derives de 3-(4-oxo-4h-chromen-2-yl)-(1h)-quinolein-4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
NO20045540L true NO20045540L (no) 2004-12-17
NO331618B1 NO331618B1 (no) 2012-02-06

Family

ID=29719853

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045540A NO331618B1 (no) 2002-06-19 2004-12-17 Nye 3-(4-okso-4H-kromen-2-yl)-(1H)-kinolin-4-on-forbindelser, en fremgangsmate for deres fremstilling og farmasoytisk sammensetninger inneholdende dem

Country Status (26)

Country Link
US (1) US7339061B2 (no)
EP (1) EP1513833B1 (no)
JP (1) JP4252035B2 (no)
KR (1) KR100645138B1 (no)
CN (1) CN1313462C (no)
AR (1) AR040276A1 (no)
AT (1) ATE323698T1 (no)
AU (1) AU2003269003B2 (no)
BR (1) BR0311956A (no)
CA (1) CA2489136C (no)
DE (1) DE60304703T2 (no)
DK (1) DK1513833T3 (no)
EA (1) EA008285B1 (no)
ES (1) ES2263013T3 (no)
FR (1) FR2841243B1 (no)
GE (1) GEP20084296B (no)
HK (1) HK1081191A1 (no)
MA (1) MA27260A1 (no)
MX (1) MXPA04012795A (no)
NO (1) NO331618B1 (no)
NZ (1) NZ537314A (no)
PL (1) PL210722B1 (no)
PT (1) PT1513833E (no)
UA (1) UA78808C2 (no)
WO (1) WO2004000834A1 (no)
ZA (1) ZA200410048B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070287699A1 (en) * 2006-05-01 2007-12-13 Virobay, Inc. Antiviral agents
FR2912145B1 (fr) * 2007-02-02 2009-03-06 Servier Lab Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP3478269A4 (en) * 2016-06-29 2020-04-08 Otonomy, Inc. OTIC FORMULATIONS BASED ON TRIGLYCERIDES AND THEIR USES
RU2642426C1 (ru) * 2017-03-21 2018-01-25 Федеральное государственное бюджетное учреждение науки Институт органического синтеза им. И.Я. Постовского Уральского отделения Российской академии наук (ИОС УрО РАН) 1-Этил-6-фтор-4-оксо-7-(8-этокси-2-оксо-2Н-хромен-3-ил)-1,4-дигидрохинолин-3-карбоновая кислота, обладающая противотуберкулезной активностью
CN112225744A (zh) * 2020-08-31 2021-01-15 兰州大学 一种6H-苯并吡喃并[3,4-b]喹啉类化合物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0733743A (ja) * 1993-07-22 1995-02-03 Kyorin Pharmaceut Co Ltd ２−アリール−４−キノリノール誘導体
CA2182932A1 (en) * 1995-08-10 1997-02-11 Koju Watanabe Chromone derivative, process for preparing same and pharmaceutical composition
TW349948B (en) * 1995-10-31 1999-01-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 2-quinolone derivatives
DE19850131A1 (de) * 1998-10-30 2000-05-04 Merck Patent Gmbh Chromenon- und Chromanonderivate

Also Published As

Publication number Publication date
ATE323698T1 (de) 2006-05-15
EP1513833B1 (fr) 2006-04-19
JP2005533077A (ja) 2005-11-04
AR040276A1 (es) 2005-03-23
KR100645138B1 (ko) 2006-11-10
AU2003269003B2 (en) 2009-05-28
MXPA04012795A (es) 2005-02-24
PL210722B1 (pl) 2012-02-29
US7339061B2 (en) 2008-03-04
CA2489136A1 (fr) 2003-12-31
JP4252035B2 (ja) 2009-04-08
NZ537314A (en) 2007-07-27
HK1081191A1 (en) 2006-05-12
FR2841243B1 (fr) 2004-08-20
DE60304703T2 (de) 2007-04-05
CA2489136C (fr) 2010-05-25
PT1513833E (pt) 2006-07-31
DE60304703D1 (de) 2006-05-24
DK1513833T3 (da) 2006-08-21
NO331618B1 (no) 2012-02-06
CN1313462C (zh) 2007-05-02
FR2841243A1 (fr) 2003-12-26
BR0311956A (pt) 2005-03-29
EA008285B1 (ru) 2007-04-27
AU2003269003A1 (en) 2004-01-06
UA78808C2 (en) 2007-04-25
MA27260A1 (fr) 2005-03-01
EP1513833A1 (fr) 2005-03-16
EA200500028A1 (ru) 2005-06-30
ES2263013T3 (es) 2006-12-01
KR20050008833A (ko) 2005-01-21
WO2004000834A1 (fr) 2003-12-31
PL372984A1 (en) 2005-08-08
ZA200410048B (en) 2006-07-26
US20060063801A1 (en) 2006-03-23
GEP20084296B (en) 2008-01-25
CN1692110A (zh) 2005-11-02

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