[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

NO20023276L - Fremgangsmåter fremstilling av betulinsyre - Google Patents

Fremgangsmåter fremstilling av betulinsyre

Info

Publication number
NO20023276L
NO20023276L NO20023276A NO20023276A NO20023276L NO 20023276 L NO20023276 L NO 20023276L NO 20023276 A NO20023276 A NO 20023276A NO 20023276 A NO20023276 A NO 20023276A NO 20023276 L NO20023276 L NO 20023276L
Authority
NO
Norway
Prior art keywords
betulin
acetate
betulinic acid
dibenzoate
betulinic
Prior art date
Application number
NO20023276A
Other languages
English (en)
Other versions
NO20023276D0 (no
Inventor
Pavel A Krasutsky
Robert M Carlson
Vitaliy V Nesterenko
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of NO20023276D0 publication Critical patent/NO20023276D0/no
Publication of NO20023276L publication Critical patent/NO20023276L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/29—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/52—Ortho- or ortho- and peri-condensed systems containing five condensed rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
NO20023276A 2000-01-11 2002-07-05 Fremgangsmåter fremstilling av betulinsyre NO20023276L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/480,406 US6232481B1 (en) 2000-01-11 2000-01-11 Method for manufacturing betulinic acid
PCT/US2001/000991 WO2001051451A2 (en) 2000-01-11 2001-01-11 Methods for manufacturing betulinic acid

Publications (2)

Publication Number Publication Date
NO20023276D0 NO20023276D0 (no) 2002-07-05
NO20023276L true NO20023276L (no) 2002-09-09

Family

ID=23907841

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023276A NO20023276L (no) 2000-01-11 2002-07-05 Fremgangsmåter fremstilling av betulinsyre

Country Status (10)

Country Link
US (4) US6232481B1 (no)
EP (1) EP1248766B1 (no)
JP (1) JP2003519674A (no)
AT (1) ATE328862T1 (no)
AU (1) AU5789601A (no)
CA (1) CA2396574A1 (no)
DE (1) DE60120352T2 (no)
ES (1) ES2264694T3 (no)
NO (1) NO20023276L (no)
WO (1) WO2001051451A2 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6232481B1 (en) * 2000-01-11 2001-05-15 Regents Of The University Of Minnesota Method for manufacturing betulinic acid
US7407480B2 (en) * 2001-07-27 2008-08-05 Ams Research Corporation Method and apparatus for correction of urinary and gynecological pathologies, including treatment of incontinence cystocele
EP1869063A2 (en) * 2005-03-29 2007-12-26 Regents Of The University Of Minnesota Methods of manufacturing bioactive 3-esters of betulinic aldehyde and betulinic acid
WO2006105357A2 (en) * 2005-03-29 2006-10-05 Regents Of The University Of Minnesota Electrochemical method for the production of betulin aldehyde
CA2603124A1 (en) * 2005-03-29 2006-10-05 Regents Of The University Of Minnesota Selective oxidation of triterpenes employing tempo
US20090131714A1 (en) * 2005-06-08 2009-05-21 Krasutsky Pavel A Synthesis of betulonic and betulinic aldehydes
CA2649704A1 (en) * 2006-04-18 2007-10-25 Regents Of The University Of Minnesota Depolymerization extraction of compounds from birch bark
KR100941595B1 (ko) * 2008-06-05 2010-02-11 주식회사 알앤엘바이오 바이러스 억제제로서 유용한 트리테르페노이드계 화합물
CN101302244B (zh) * 2008-06-06 2011-04-13 东北林业大学 一种桦木酸的生产方法
CN102399255B (zh) * 2010-09-09 2015-04-15 东北林业大学 一种桦木酸的制备方法
RU2560710C1 (ru) * 2014-10-30 2015-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Химии И Химической Технологии Сибирского Отделения Российской Академии Наук (Иххт Со Ран) Способ получения производных 3-ацетата-28-сульфата бетулина
PL227790B1 (pl) 2015-08-13 2018-01-31 Slaski Univ Medyczny W Katowicach Fosfoniany acetylenowych pochodnych betuliny o działaniu przeciwnowotworowym, sposób ich wytwarzania i zastosowanie.
CN110577470B (zh) * 2019-10-09 2022-12-27 蚌埠学院 一种利用沸石分子筛催化2-萘甲醚选择性硝化的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW212790B (no) 1991-10-15 1993-09-11 Ciba Geigy Ag
US5804575A (en) * 1997-03-27 1998-09-08 The Board Of Trustees Of The University Of Illinois Methods of manufacturing betulinic acid
DK1068219T3 (da) * 1998-03-02 2007-04-30 Univ North Carolina Acylerede betulin- og dihydrobetulinderivater samt fremstilling og anvendelse deraf
US6232481B1 (en) * 2000-01-11 2001-05-15 Regents Of The University Of Minnesota Method for manufacturing betulinic acid

Also Published As

Publication number Publication date
WO2001051451A2 (en) 2001-07-19
US20020028960A1 (en) 2002-03-07
WO2001051451A3 (en) 2002-03-07
US6867314B2 (en) 2005-03-15
US6232481B1 (en) 2001-05-15
ES2264694T3 (es) 2007-01-16
US20020016482A1 (en) 2002-02-07
EP1248766A2 (en) 2002-10-16
DE60120352T2 (de) 2007-04-26
AU5789601A (en) 2001-07-24
ATE328862T1 (de) 2006-06-15
DE60120352D1 (de) 2006-07-20
CA2396574A1 (en) 2001-07-19
US6407270B1 (en) 2002-06-18
EP1248766B1 (en) 2006-06-07
US20010007908A1 (en) 2001-07-12
NO20023276D0 (no) 2002-07-05
US6271405B2 (en) 2001-08-07
JP2003519674A (ja) 2003-06-24

Similar Documents

Publication Publication Date Title
NO20023276L (no) Fremgangsmåter fremstilling av betulinsyre
RS53562B1 (sr) Tripeptidi, inhibitori hepatitisa c
IT1317034B1 (it) Metodo di estrazione di prodotti ad attivita' farmaceutica da piantespermatofite, prodotti cosi' ottenuti e loro impiego in medicina, in
HUP0303354A2 (hu) Gyulladásgátló hatású 6-alfa, 9-alfa-difluor-17-alfa-(2-furanilkarbonil)oxi-11-béta-hidroxi-16-alfa-metil-3-oxo-androst-1,4-dién-17-tiokarbonsav-S-fluormetil-észter, eljárás az előállítására és ezt tartalmazó gyógyszerkészítmény
NO20020651D0 (no) Björkebarkbehandling og isolering av naturprodukter fra björkebark
ES2189768T3 (es) Sintesis regioselectiva de derivados de rapamicina.
DK1257531T3 (da) Fremgangsmåde til fremstilling af carbothiosyre
ATE250077T1 (de) Steroid sulfataseinhibitoren, verfahren zu ihrer herstellung und verwendung
AU2001263300A8 (en) Post-added alpha-sulfofatty acid ester compositions and methods of making and using the same
DK32684A (da) Fremgangsmaade til fremstilling af 26,26,26,27,27,27-hexafluor-1alfa,25-dihydroxycholesterol og mellemprodukter til brug herfor
DK1301526T3 (da) Fremgangsmåde til oxidation til fremstilling af mellemproduktet 6.alpha.,9alpha.-difluor-11.beta.,17.alpha.-dihydroxy-16.alpha.-methyl-androst-1,4-dien-3-on 17.beta-carboxylsyre
RS83104A (en) Process to prepare eplerenone
ATE302749T1 (de) Verfahren zur herstellung von 5-aminosalicylsäure
AU1382202A (en) 17alpha fluoroalkyl steroids, method for producing the same and pharmaceutical compositions containing said compounds
DE60003807D1 (de) Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
HU0102118D0 (en) Process for chloromethylation
DK1001929T3 (da) Fremgangsmåde til fremstilling af 3-cyano-2,4-dihalogen-5-flour-benzoesyrer
DK1196428T3 (da) 11-beta-aryl-17,17-spirothiolan-substituerede steroider
DE60014103D1 (de) Verfahren zur herstellung von debromohymenialdisin und deren analogen
TR200200307T2 (tr) Alfa-Kloroepoksi esterleri vasıtasıyla asit hazırlama prosesi
NO20020328L (no) Fremgangsmåte for fremstilling av 4-cyano-2-aminometyltiazol
DK1163257T3 (da) Fremgangsmåde til fremstilling af 4,4-dimethyl-3beta-hydroxypregna-8,14-dien-21-carboxylsyreestere og mellemprodukter i fremgangsmåden
DK0866798T3 (da) Fremstilling af esterderivater af steroider
ATE81508T1 (de) Herstellung von corticoiden aus steroidischen 17- cyanohydrinen.
AU5650590A (en) Oxidative preparation of a-nor-17 beta-carboxy-3,5-secoandrostan-5-one-3 oic acid