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NO20014262L - Tiazoloindolinon compounds - Google Patents

Tiazoloindolinon compounds

Info

Publication number
NO20014262L
NO20014262L NO20014262A NO20014262A NO20014262L NO 20014262 L NO20014262 L NO 20014262L NO 20014262 A NO20014262 A NO 20014262A NO 20014262 A NO20014262 A NO 20014262A NO 20014262 L NO20014262 L NO 20014262L
Authority
NO
Norway
Prior art keywords
therapy
tiazoloindolinon
compounds
mucositis
plantar
Prior art date
Application number
NO20014262A
Other languages
Norwegian (no)
Other versions
NO20014262D0 (en
Inventor
Ambrish Yvas
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20014262D0 publication Critical patent/NO20014262D0/en
Publication of NO20014262L publication Critical patent/NO20014262L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cosmetics (AREA)

Abstract

Tiazol-indol-forbindelser anvendelige som cyklin-avhengige kinase II- inhibitorer for forebygging/redusering av alvorlighetsgraden av epiteliale cytotoksisitets-bivirkninger (for eksempel alopeci, plantar-palmar syndom, mukositt) fremkalt ved kjemoterapi og/eller strålingsterapi hos en pasient som får slik terapi.Thiazole-indole compounds useful as cyclin-dependent kinase II inhibitors for the prevention / reduction of the severity of epithelial cytotoxicity side effects (e.g., alopecia, plantar-palmar syndrome, mucositis) induced by chemotherapy and / or radiation therapy in a patient receiving such therapy. therapy.

NO20014262A 1999-03-04 2001-09-03 Tiazoloindolinon compounds NO20014262L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9904930.6A GB9904930D0 (en) 1999-03-04 1999-03-04 Thiazoloindolinone compounds
PCT/US2000/005192 WO2000052013A2 (en) 1999-03-04 2000-03-01 Thiazoloindolinone compounds

Publications (2)

Publication Number Publication Date
NO20014262D0 NO20014262D0 (en) 2001-09-03
NO20014262L true NO20014262L (en) 2001-10-30

Family

ID=10848912

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014262A NO20014262L (en) 1999-03-04 2001-09-03 Tiazoloindolinon compounds

Country Status (18)

Country Link
EP (1) EP1159280A2 (en)
JP (1) JP2003532620A (en)
KR (1) KR20020005606A (en)
CN (1) CN1355807A (en)
AU (1) AU3611000A (en)
BR (1) BR0008677A (en)
CA (1) CA2361580A1 (en)
CZ (1) CZ20013187A3 (en)
GB (1) GB9904930D0 (en)
HK (1) HK1041692A1 (en)
HU (1) HUP0200376A3 (en)
IL (1) IL144808A0 (en)
MX (1) MXPA01008910A (en)
NO (1) NO20014262L (en)
PL (1) PL351476A1 (en)
TR (1) TR200102557T2 (en)
WO (1) WO2000052013A2 (en)
ZA (1) ZA200106826B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
TW200628483A (en) * 2004-12-01 2006-08-16 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Processes for producing crystalline macrolides
UA103319C2 (en) * 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
EP2554184B1 (en) 2010-03-31 2016-10-26 ONO Pharmaceutical Co., Ltd. Preventive and/or remedy for hand and foot syndrome
JP4761000B1 (en) * 2010-11-08 2011-08-31 小野薬品工業株式会社 Preventive and / or therapeutic agent for hand-foot syndrome
TW201927292A (en) 2017-12-13 2019-07-16 大陸商上海小午醫藥科技有限公司 A method for preventing or treating a disease associated with inhibition of EGFR
EP3782618A4 (en) 2018-04-16 2022-01-26 OnQuality Pharmaceuticals China Ltd. Method for preventing or treating side effects of cancer therapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2289102A1 (en) * 1997-05-07 1998-11-12 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives

Also Published As

Publication number Publication date
MXPA01008910A (en) 2002-03-27
HUP0200376A2 (en) 2002-06-29
NO20014262D0 (en) 2001-09-03
AU3611000A (en) 2000-09-21
ZA200106826B (en) 2003-02-25
CZ20013187A3 (en) 2002-02-13
PL351476A1 (en) 2003-04-22
BR0008677A (en) 2002-01-08
WO2000052013A2 (en) 2000-09-08
GB9904930D0 (en) 1999-04-28
TR200102557T2 (en) 2007-01-22
JP2003532620A (en) 2003-11-05
CN1355807A (en) 2002-06-26
EP1159280A2 (en) 2001-12-05
WO2000052013A3 (en) 2000-12-28
CA2361580A1 (en) 2000-09-08
KR20020005606A (en) 2002-01-17
HK1041692A1 (en) 2002-07-19
HUP0200376A3 (en) 2003-07-28
IL144808A0 (en) 2002-06-30

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application