NO20014875L - Promedikamenter for trombin inhibitorer - Google Patents

Promedikamenter for trombin inhibitorer

Info

Publication number: NO20014875L
Authority: NO; Norway
Prior art keywords: promedients; thrombin inhibitors; thrombin; inhibitors
Prior art date: 1999-04-09

Application number

NO20014875A

Other languages

English (en)

Other versions

NO20014875D0 (no

Inventor

Dorit Baucke

Helmut Mack

Werner Seitz

Wilfried Hornberger

Gisela Backfish

Juergen DELZER

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-09

Filing date

2001-10-08

Publication date

2001-11-13

2001-10-08 Application filed by Basf Ag filed Critical Basf Ag

2001-10-08 Publication of NO20014875D0 publication Critical patent/NO20014875D0/no

2001-11-13 Publication of NO20014875L publication Critical patent/NO20014875L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hematology (AREA)
Diabetes (AREA)
Oncology (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20014875A 1999-04-09 2001-10-08 Promedikamenter for trombin inhibitorer NO20014875L (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DE19915930		1999-04-09
DE19934123		1999-07-23
DE19947920		1999-10-06
PCT/EP2000/003009 WO2000061609A2 (de)	1999-04-09	2000-04-05	Prodrugs von thrombininhibitoren

Publications (2)

Publication Number	Publication Date
NO20014875D0 NO20014875D0 (no)	2001-10-08
NO20014875L true NO20014875L (no)	2001-11-13

Family

ID=27219075

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20014875A NO20014875L (no)	1999-04-09	2001-10-08	Promedikamenter for trombin inhibitorer

Country Status (18)

Country	Link
US (1)	US7144902B1 (no)
EP (1)	EP1165601A2 (no)
JP (1)	JP2002542165A (no)
KR (1)	KR20010108481A (no)
CN (1)	CN1355810A (no)
AU (1)	AU765244B2 (no)
BG (1)	BG105986A (no)
BR (1)	BR0009674A (no)
CA (1)	CA2370267A1 (no)
HK (1)	HK1046289A1 (no)
HU (1)	HUP0202401A3 (no)
IL (1)	IL145772A0 (no)
NO (1)	NO20014875L (no)
NZ (1)	NZ515026A (no)
PL (1)	PL352824A1 (no)
SK (1)	SK14222001A3 (no)
TR (1)	TR200102912T2 (no)
WO (1)	WO2000061609A2 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10064797A1 (de) *	2000-12-22	2002-06-27	Knoll Ag	Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
WO2004002985A1 (en) *	2002-06-27	2004-01-08	Lg Life Sciences Ltd.	Peptidic thrombin inhibitor compound
KR101154246B1 (ko)	2003-05-16	2012-06-13	내셔날 인스티튜트 포 바이올로지칼 스탠다즈 앤 컨트롤 (엔아이비에스씨)	활성화 혼합물
US7939629B2 (en)	2004-10-19	2011-05-10	Lonza Ag	Method for solid phase peptide synthesis
PL1877098T3 (pl) *	2005-05-05	2013-09-30	Glaxosmithkline Ip Dev Ltd	Koniugaty estru alfa-aminokwasu z lekiem ulegające hydrolizie z udziałem karboksyloesterazy
ES2578404T3 (es)	2005-05-10	2016-07-26	Incyte Holdings Corporation	Moduladores de la indolamina 2,3-dioxigenasa, y métodos de uso de los mismos
US8450351B2 (en)	2005-12-20	2013-05-28	Incyte Corporation	N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es) *	2006-09-19	2008-02-08	Incyte Corp	Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
JP5319532B2 (ja) *	2006-09-19	2013-10-16	インサイト・コーポレイション	インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル
DK2824100T3 (en)	2008-07-08	2018-04-16	Incyte Holdings Corp	1,2,5-oxadiazoles as inhibitors of indolamine-2,3-dioxygenase
US9206123B2 (en)	2009-12-18	2015-12-08	Activesite Pharmaceuticals, Inc.	Prodrugs of inhibitors of plasma kallikrein
AU2010330743A1 (en) *	2009-12-18	2012-07-05	Activesite Pharmaceuticals, Inc.	Prodrugs of inhibitors of plasma kallikrein
EP2697196A1 (en)	2011-04-13	2014-02-19	Activesite Pharmaceuticals, Inc.	Prodrugs of inhibitors of plasma kallikrein
SG10201803874PA (en)	2013-11-08	2018-07-30	Incyte Holdings Corp	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor
US10081624B2 (en) *	2014-08-26	2018-09-25	Takeda Pharmaceutical Company Limited	Heterocyclic compound
CN106674190B (zh) *	2016-12-13	2019-05-10	台州市创源工业技术有限公司	一种2-噻吩甲胺的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA951617B (en) *	1994-03-04	1997-02-27	Lilly Co Eli	Antithrombotic agents.
AR005245A1 (es) *	1995-12-21	1999-04-28	Astrazeneca Ab	Prodrogas de inhibidores de trombina, una formulación farmaceutica que las comprende, el uso de dichas prodrogas para la manufactura de un medicamento y un procedimiento para su preparacion
TW523513B (en)	1996-03-01	2003-03-11	Akzo Nobel Nv	Serine protease inhibitors
DE19632773A1 (de)	1996-08-14	1998-02-19	Basf Ag	Neue Thrombininhibitoren
WO1999037668A1 (de)	1998-01-26	1999-07-29	Basf Aktiengesellschaft	Thrombininhibitoren
EP1049673A1 (de)	1998-01-26	2000-11-08	Basf Aktiengesellschaft	Heterocyclische amidine als kallikrein protease inhibitoren
KR20000047461A (ko) *	1998-12-29	2000-07-25	성재갑	트롬빈 억제제
IL145771A0 (en) *	1999-04-09	2002-07-25	Basf Ag	Low-molecular inhibitors of complement proteases

2000
- 2000-04-05 WO PCT/EP2000/003009 patent/WO2000061609A2/de not_active Application Discontinuation
- 2000-04-05 CN CN00807958A patent/CN1355810A/zh active Pending
- 2000-04-05 TR TR2001/02912T patent/TR200102912T2/xx unknown
- 2000-04-05 AU AU41156/00A patent/AU765244B2/en not_active Ceased
- 2000-04-05 JP JP2000611551A patent/JP2002542165A/ja active Pending
- 2000-04-05 PL PL00352824A patent/PL352824A1/xx unknown
- 2000-04-05 SK SK1422-2001A patent/SK14222001A3/sk not_active Application Discontinuation
- 2000-04-05 US US09/958,349 patent/US7144902B1/en not_active Expired - Fee Related
- 2000-04-05 KR KR1020017012870A patent/KR20010108481A/ko not_active Application Discontinuation
- 2000-04-05 CA CA002370267A patent/CA2370267A1/en not_active Abandoned
- 2000-04-05 NZ NZ515026A patent/NZ515026A/en unknown
- 2000-04-05 HU HU0202401A patent/HUP0202401A3/hu unknown
- 2000-04-05 BR BR0009674-1A patent/BR0009674A/pt not_active IP Right Cessation
- 2000-04-05 IL IL14577200A patent/IL145772A0/xx unknown
- 2000-04-05 EP EP00920661A patent/EP1165601A2/de not_active Withdrawn
2001
- 2001-10-05 BG BG105986A patent/BG105986A/bg unknown
- 2001-10-08 NO NO20014875A patent/NO20014875L/no not_active Application Discontinuation
2002
- 2002-10-30 HK HK02107849.6A patent/HK1046289A1/zh unknown

Also Published As

Publication number	Publication date
US7144902B1 (en)	2006-12-05
EP1165601A2 (de)	2002-01-02
NO20014875D0 (no)	2001-10-08
BR0009674A (pt)	2002-01-15
HUP0202401A3 (en)	2003-11-28
AU4115600A (en)	2000-11-14
SK14222001A3 (sk)	2002-07-02
WO2000061609B1 (de)	2001-04-26
TR200102912T2 (tr)	2002-03-21
JP2002542165A (ja)	2002-12-10
KR20010108481A (ko)	2001-12-07
HK1046289A1 (zh)	2003-01-03
IL145772A0 (en)	2002-07-25
WO2000061609A3 (de)	2001-03-15
CA2370267A1 (en)	2000-10-19
BG105986A (bg)	2002-06-28
NZ515026A (en)	2003-10-31
WO2000061609A2 (de)	2000-10-19
HUP0202401A2 (en)	2002-10-28
CN1355810A (zh)	2002-06-26
PL352824A1 (en)	2003-09-08
AU765244B2 (en)	2003-09-11

Publication	Publication Date	Title
ATE237329T1 (de)	2003-05-15	Metalloprotease inhibitoren
DE60017180D1 (de)	2005-02-03	Fab i inhibitoren
NO20012980D0 (no)	2001-06-15	Proteaseinhibitorer
PT1224195E (pt)	2005-07-29	C-aril-glicosidos inibidores de tgls2
PT1194404E (pt)	2006-08-31	Inibidores de aspartil-protease
ATE512949T1 (de)	2011-07-15	Reninhemmer
ATE524441T1 (de)	2011-09-15	Vla-4-inhibitoren
CY2012007I2 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
DE60008527D1 (de)	2004-04-01	Zellproliferation inhibitoren
ATE363478T1 (de)	2007-06-15	Renin inhibitoren
DK1272488T3 (da)	2006-07-17	Tri-aryl-substitueret ethan-PDE4-inhibitorer
NO20014243L (no)	2001-10-17	Dihetero-substituerte metalloproteaseinhibitorer
NO20014875L (no)	2001-11-13	Promedikamenter for trombin inhibitorer
NO20023013D0 (no)	2002-06-21	Substituerte 8-arylkinolinfosfodiesterase-4-inhibitorer
NO20003814D0 (no)	2000-07-25	Trombininhibitorer
NO20021658D0 (no)	2002-04-08	Asfaltenhemmere
ATE252547T1 (de)	2003-11-15	Matrixmetalloproteinaseinhibitoren
PT1189929E (pt)	2003-12-31	Inibidores do factor viia
DE60024101D1 (de)	2005-12-22	Enzyminhibitoren
PT1339695E (pt)	2006-08-31	Inibidores da farnesiltransferase
DE60009260D1 (de)	2004-04-29	Thiopyranderivate as mmp-inhibitoren
AR028075A1 (es)	2003-04-23	Inhibidores de la peptido-desformilasa
EP1189618A4 (en)	2002-06-19	thrombin
DOP2001000307A (es)	2002-11-30	Inhibidores de thrombin

Legal Events

Date	Code	Title	Description
2006-11-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application