NO20014792D0 - With sugar residues substituted 1,4-benzothiazepine-1,1-dioxide derivatives, process for their preparation, drugs containing them and compounds and their use - Google Patents
With sugar residues substituted 1,4-benzothiazepine-1,1-dioxide derivatives, process for their preparation, drugs containing them and compounds and their useInfo
- Publication number
- NO20014792D0 NO20014792D0 NO20014792A NO20014792A NO20014792D0 NO 20014792 D0 NO20014792 D0 NO 20014792D0 NO 20014792 A NO20014792 A NO 20014792A NO 20014792 A NO20014792 A NO 20014792A NO 20014792 D0 NO20014792 D0 NO 20014792D0
- Authority
- NO
- Norway
- Prior art keywords
- benzothiazepine
- compounds
- preparation
- sugar residues
- drugs containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19916108A DE19916108C1 (en) | 1999-04-09 | 1999-04-09 | 1,4-Benzothiazepine-1,1-dioxide derivatives substituted with sugar residues, process for their preparation and their use |
PCT/EP2000/002570 WO2000061568A2 (en) | 1999-04-09 | 2000-03-23 | 1,4-benzothiazepine-1,1-dioxide derivatives substituted by sugar radicals, methods for the production thereof, medicaments containing these compounds and the use thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20014792D0 true NO20014792D0 (en) | 2001-10-02 |
NO20014792L NO20014792L (en) | 2001-10-02 |
NO319836B1 NO319836B1 (en) | 2005-09-19 |
Family
ID=7904060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20014792A NO319836B1 (en) | 1999-04-09 | 2001-10-02 | With sugar residues substituted 1,4-benzothiazepine-1,1-dioxide derivatives, process for their preparation, drugs containing them and compounds and their use |
Country Status (32)
Country | Link |
---|---|
US (1) | US6277831B1 (en) |
EP (1) | EP1169313B1 (en) |
JP (1) | JP2002541248A (en) |
KR (1) | KR100686905B1 (en) |
CN (1) | CN1145619C (en) |
AR (1) | AR023401A1 (en) |
AT (1) | ATE243686T1 (en) |
AU (1) | AU765199B2 (en) |
BR (1) | BR0009641A (en) |
CA (1) | CA2369070C (en) |
CZ (1) | CZ300410B6 (en) |
DE (2) | DE19916108C1 (en) |
DK (1) | DK1169313T3 (en) |
EE (1) | EE04613B1 (en) |
ES (1) | ES2200860T3 (en) |
HK (1) | HK1044537B (en) |
HR (1) | HRP20010725A2 (en) |
HU (1) | HUP0200644A3 (en) |
IL (2) | IL145647A0 (en) |
MY (1) | MY120842A (en) |
NO (1) | NO319836B1 (en) |
NZ (1) | NZ514656A (en) |
PL (1) | PL203806B1 (en) |
PT (1) | PT1169313E (en) |
RS (1) | RS49850B (en) |
RU (1) | RU2232155C2 (en) |
SI (1) | SI1169313T1 (en) |
SK (1) | SK286744B6 (en) |
TR (1) | TR200102910T2 (en) |
TW (1) | TWI254045B (en) |
WO (1) | WO2000061568A2 (en) |
ZA (1) | ZA200107989B (en) |
Families Citing this family (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6268392B1 (en) * | 1994-09-13 | 2001-07-31 | G. D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors |
US6262277B1 (en) * | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
US6221897B1 (en) * | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
WO2000038722A1 (en) * | 1998-12-23 | 2000-07-06 | G.D. Searle & Co. | COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS |
HUP0104793A2 (en) * | 1998-12-23 | 2002-06-29 | Searle Llc | Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications |
JP2002533414A (en) * | 1998-12-23 | 2002-10-08 | ジー.ディー.サール エルエルシー | Combination of ileal bile acid transport inhibitors and bile acid sequestrants for cardiovascular applications |
DK1140184T3 (en) * | 1998-12-23 | 2003-09-29 | Searle Llc | Combinations of cholesterol ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications |
DE69908645T2 (en) * | 1998-12-23 | 2004-05-13 | G.D. Searle Llc, Chicago | COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND FIBRONIC ACID DERIVATIVES FOR CARDIOVASCULAR INDICATIONS |
DE69908414T2 (en) * | 1998-12-23 | 2004-04-01 | G.D. Searle Llc, Chicago | COMBINATIONS OF ILEUMGALLIC ACID TRANSPORTS INHIBITORS AND CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS |
AU776952B2 (en) * | 1998-12-23 | 2004-09-30 | G.D. Searle Llc | Combinations of ileal bile acid transport inhibitors and nicotinic acid derivatives for cardiovascular indications |
SE0000772D0 (en) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
US20020183307A1 (en) * | 2000-07-26 | 2002-12-05 | Tremont Samuel J. | Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake |
EG26979A (en) | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
NZ526593A (en) * | 2000-12-21 | 2005-02-25 | Aventis Pharma Gmbh | Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism |
HUP0401696A2 (en) * | 2001-08-28 | 2004-11-29 | Sankyo Co., Ltd. | Medicinal compositions containing angiotensin ii receptor antagonist |
GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
TWI331143B (en) | 2001-09-08 | 2010-10-01 | Astrazeneca Uk Ltd | Benzothiadiazepine derivatives, process for preparing them, and pharmaceutical composition comprising them |
GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
EP1526857A1 (en) * | 2002-07-23 | 2005-05-04 | Nutrinova Nutrition Specialties & Food Ingredients GmbH | Cholesterol-reducing agent made of dietary fibre and cholesterol-reducing substances |
KR100990524B1 (en) * | 2002-08-28 | 2010-10-29 | 아사히 가세이 파마 가부시키가이샤 | Novel quaternary ammonium compounds |
US7312208B2 (en) | 2002-08-28 | 2007-12-25 | Asahi Kasei Pharma Corporation | Quaternary ammonium compounds |
DE10261061A1 (en) * | 2002-12-24 | 2004-07-15 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Dietary food to positively influence cardiovascular health |
DE10261067A1 (en) * | 2002-12-24 | 2004-08-05 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Cholesterol-lowering agent containing an n-3 fatty acid |
GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
DE10308351A1 (en) * | 2003-02-27 | 2004-11-25 | Aventis Pharma Deutschland Gmbh | 1,3-substituted cycloalkyl derivatives having acidic, usually heterocyclic groups, processes for their preparation and their use as medicaments |
DE10308353A1 (en) * | 2003-02-27 | 2004-12-02 | Aventis Pharma Deutschland Gmbh | Diarylcycloalkyl derivatives, processes for their preparation and their use as medicines |
DE10308352A1 (en) * | 2003-02-27 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Branched side chain arylcycloalkyl derivatives, process for their preparation and their use as medicaments |
US7148246B2 (en) * | 2003-02-27 | 2006-12-12 | Sanofi-Aventis Deutschland Gmbh | Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals |
US7173151B2 (en) * | 2003-02-27 | 2007-02-06 | Sanofi-Aventisdeutschand Gmbh | Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals |
DE10308355A1 (en) * | 2003-02-27 | 2004-12-23 | Aventis Pharma Deutschland Gmbh | Aryl-cycloalkyl-substituted alkanoic acid derivatives, process for their preparation and their use as medicaments |
CA2517571C (en) * | 2003-03-07 | 2011-07-05 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
ATE418551T1 (en) * | 2003-03-07 | 2009-01-15 | Schering Corp | SUBSTITUTED AZETIDINONE DERIVATIVES, THEIR PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF HYPERCHOLESTEROLEMIA |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
KR20060109926A (en) | 2003-11-19 | 2006-10-23 | 메타베이시스 테라퓨틱스, 인크. | Novel phosphorus-containing thyromimetics |
US7241787B2 (en) * | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
AU2005217318B2 (en) * | 2004-02-27 | 2010-07-01 | Asahi Kasei Pharma Corporation | Novel benzothiazepine and benzothiepine compounds |
EP1586573B1 (en) | 2004-04-01 | 2007-02-07 | Sanofi-Aventis Deutschland GmbH | Oxadiazolones, processes for their preparation and their use as pharmaceuticals |
DE102005026762A1 (en) | 2005-06-09 | 2006-12-21 | Sanofi-Aventis Deutschland Gmbh | Azolopyridin-2-one derivatives as inhibitors of lipases and phospholipases |
DE102005033099A1 (en) | 2005-07-15 | 2007-01-18 | Sanofi-Aventis Deutschland Gmbh | Novel 1,4-benzothiazepine 1,1-dioxide derivative with improved properties, process for its preparation, medicines containing it and its use |
DE102005033100B3 (en) * | 2005-07-15 | 2007-01-25 | Sanofi-Aventis Deutschland Gmbh | Novel 1,4-benzothiazepine-1,1-dioxide derivative with improved properties, drugs containing this compound and methods for their preparation |
RU2008112198A (en) | 2005-09-29 | 2009-10-10 | Санофи-Авентис (Fr) | DERIVATIVES OF PHENYL-1,2,4-OXADIAZAZOLONE, METHODS FOR THEIR PRODUCTION AND THEIR APPLICATION AS PHARMACEUTICAL PRODUCTS |
AU2007283113A1 (en) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use |
DE102007005045B4 (en) | 2007-01-26 | 2008-12-18 | Sanofi-Aventis | Phenothiazine derivatives, process for their preparation and their use as medicines |
DE102007063671A1 (en) | 2007-11-13 | 2009-06-25 | Sanofi-Aventis Deutschland Gmbh | New crystalline diphenylazetidinone hydrates, medicaments containing these compounds and their use |
WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
US20120046364A1 (en) | 2009-02-10 | 2012-02-23 | Metabasis Therapeutics, Inc. | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use |
EP4137137A1 (en) | 2010-05-26 | 2023-02-22 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
EP2582709B1 (en) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
SG190433A1 (en) | 2010-11-08 | 2013-06-28 | Albireo Ab | A pharmaceutical combination comprising an ibat inhibitor and a bile acid binder |
SG190029A1 (en) | 2010-11-08 | 2013-06-28 | Albireo Ab | Ibat inhibitors for the treatment of liver diseases |
RU2454423C1 (en) * | 2010-12-27 | 2012-06-27 | Государственное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения и социального развития РФ | 2-mercaptobenzoyl hydrazones of monose, having antimicrobial and antifungal activity |
EP2766349B1 (en) | 2011-03-08 | 2016-06-01 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
EP2683699B1 (en) | 2011-03-08 | 2015-06-24 | Sanofi | Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683702B1 (en) | 2011-03-08 | 2014-12-24 | Sanofi | New substituted phenyl oxathiazine derivatives, method for their manufacture, medicines containing these compounds and their application |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
WO2012120057A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
WO2012120056A1 (en) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
EP2567959B1 (en) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
CA2853285C (en) | 2011-10-28 | 2020-05-05 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
BR112014010228B1 (en) | 2011-10-28 | 2020-09-29 | Lumena Pharmaceuticals Llc | USE OF BILIARY ACID RECYCLING INHIBITORS FOR THE TREATMENT OF HYPERCOLEMIA AND CHOLESTATIC HEPATIC DISEASE |
WO2014144485A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
MX2015013193A (en) | 2013-03-15 | 2016-04-15 | Lumena Pharmaceuticals Inc | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease. |
JO3301B1 (en) | 2013-04-26 | 2018-09-16 | Albireo Ab | Crystal modifications of elobixibat |
JP6751020B2 (en) | 2014-06-25 | 2020-09-02 | Eaファーマ株式会社 | Solid preparation and method for preventing or reducing coloration thereof |
EP3012252A1 (en) | 2014-10-24 | 2016-04-27 | Ferring BV | Crystal modifications of elobixibat |
US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
EP3413878B1 (en) | 2016-02-09 | 2021-04-14 | Albireo AB | Oral cholestyramine formulation and use thereof |
RU2750944C2 (en) | 2016-02-09 | 2021-07-06 | Альбирео Аб | Oral cholestyramine composition and application thereof |
US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
AU2017286943B2 (en) * | 2016-06-27 | 2019-05-09 | Glaxosmithkline Intellectual Property (No.2) Limited | Synthetic methods |
CN111032019B (en) | 2017-08-09 | 2022-07-05 | 阿尔比里奥公司 | Cholestyramine granules, oral cholestyramine preparation and application thereof |
WO2019032027A1 (en) | 2017-08-09 | 2019-02-14 | Albireo Ab | Cholestyramine pellets, oral cholestyramine formulations and use thereof |
JP7391048B2 (en) | 2018-06-05 | 2023-12-04 | アルビレオ・アクチボラグ | Benzothia(di)azepine compounds and their use as bile acid modulators |
US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
IL279468B2 (en) | 2018-06-20 | 2024-11-01 | Albireo Ab | Crystal modifications of odevixibat |
US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
PL3921028T3 (en) | 2019-02-06 | 2023-02-13 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
CN118834175A (en) | 2019-02-06 | 2024-10-25 | 阿尔比里奥公司 | Benzothiazacycloalkanes Heptatriene compounds use thereof as bile acid modulators |
US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
KR20210137467A (en) | 2019-02-12 | 2021-11-17 | 미룸 파마슈티컬스, 인크. | Genotype and dose-dependent response to ASBTI in patients with bile salt efflux pump deficiency |
CN114786772B (en) | 2019-12-04 | 2024-04-09 | 阿尔比里奥公司 | Benzothiazepine compounds and their use as bile acid modulators |
ES2973355T3 (en) | 2019-12-04 | 2024-06-19 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
EP4069360B1 (en) | 2019-12-04 | 2024-01-03 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
WO2021110887A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
AR120683A1 (en) | 2019-12-04 | 2022-03-09 | Albireo Ab | BENZOTHI(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILIARY ACID |
US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
TW202134221A (en) | 2019-12-04 | 2021-09-16 | 瑞典商艾爾比瑞歐公司 | Benzothiadiazepine compounds and their use as bile acid modulators |
EP4069247A1 (en) | 2019-12-04 | 2022-10-12 | Albireo AB | Benzothiadiazepine compounds and their use as bile acid modulators |
AR120679A1 (en) | 2019-12-04 | 2022-03-09 | Albireo Ab | BENZOTHI(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS |
WO2021110886A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
JP2023537285A (en) | 2020-08-03 | 2023-08-31 | アルビレオ・アクチボラグ | Benzothia(di)azepine compounds and their use as bile acid modulators |
CA3196488A1 (en) | 2020-11-12 | 2022-05-19 | Albireo Ab | Odevixibat for treating progressive familial intrahepatic cholestasis (pfic) |
BR112023010799A2 (en) | 2020-12-04 | 2023-10-03 | Albireo Ab | BENZOTIA(DI)AZEPINE COMPOUNDS AND THEIR USES AS BILLARY ACID MODULATORS |
WO2023237728A1 (en) | 2022-06-09 | 2023-12-14 | Albireo Ab | Treating hepatitis |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK406686D0 (en) * | 1986-08-26 | 1986-08-26 | Hans Bundgaard | carboxylic acid derivatives |
GB9203347D0 (en) * | 1992-02-17 | 1992-04-01 | Wellcome Found | Hypolipidaemic compounds |
IL108634A0 (en) * | 1993-02-15 | 1994-05-30 | Wellcome Found | Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them |
IL108633A (en) * | 1993-02-15 | 1998-07-15 | Wellcome Found | Hypolipidaemic benzothiazepine derivatives their preparation and pharmaceutical compositions containing them |
ZA956647B (en) * | 1994-08-10 | 1997-02-10 | Wellcome Found | Hypolipidaemic compounds. |
GB9423172D0 (en) * | 1994-11-17 | 1995-01-04 | Wellcom Foundation The Limited | Hypolipidemic benzothiazepines |
US5723589A (en) * | 1995-12-21 | 1998-03-03 | Icn Pharmaceuticals | Carbohydrate conjugated bio-active compounds |
DK0864582T3 (en) * | 1997-03-14 | 2003-09-29 | Aventis Pharma Gmbh | Hypolidemic 1,4-benzothiazepine-1,1-dioxides |
-
1999
- 1999-04-09 DE DE19916108A patent/DE19916108C1/en not_active Expired - Fee Related
-
2000
- 2000-03-23 PT PT00920550T patent/PT1169313E/en unknown
- 2000-03-23 EE EEP200100495A patent/EE04613B1/en not_active IP Right Cessation
- 2000-03-23 AU AU41087/00A patent/AU765199B2/en not_active Ceased
- 2000-03-23 DK DK00920550T patent/DK1169313T3/en active
- 2000-03-23 AT AT00920550T patent/ATE243686T1/en not_active IP Right Cessation
- 2000-03-23 HU HU0200644A patent/HUP0200644A3/en unknown
- 2000-03-23 RU RU2001129936/04A patent/RU2232155C2/en not_active IP Right Cessation
- 2000-03-23 EP EP00920550A patent/EP1169313B1/en not_active Expired - Lifetime
- 2000-03-23 IL IL14564700A patent/IL145647A0/en active IP Right Grant
- 2000-03-23 BR BR0009641-5A patent/BR0009641A/en not_active Application Discontinuation
- 2000-03-23 KR KR1020017012822A patent/KR100686905B1/en not_active IP Right Cessation
- 2000-03-23 SI SI200030186T patent/SI1169313T1/en unknown
- 2000-03-23 CA CA002369070A patent/CA2369070C/en not_active Expired - Fee Related
- 2000-03-23 JP JP2000610842A patent/JP2002541248A/en not_active Abandoned
- 2000-03-23 PL PL350984A patent/PL203806B1/en not_active IP Right Cessation
- 2000-03-23 CN CNB008060738A patent/CN1145619C/en not_active Expired - Fee Related
- 2000-03-23 ES ES00920550T patent/ES2200860T3/en not_active Expired - Lifetime
- 2000-03-23 WO PCT/EP2000/002570 patent/WO2000061568A2/en active IP Right Grant
- 2000-03-23 RS YUP-709/01A patent/RS49850B/en unknown
- 2000-03-23 DE DE50002646T patent/DE50002646D1/en not_active Expired - Lifetime
- 2000-03-23 SK SK1416-2001A patent/SK286744B6/en not_active IP Right Cessation
- 2000-03-23 NZ NZ514656A patent/NZ514656A/en not_active IP Right Cessation
- 2000-03-23 TR TR2001/02910T patent/TR200102910T2/en unknown
- 2000-03-23 CZ CZ20013610A patent/CZ300410B6/en not_active IP Right Cessation
- 2000-04-06 AR ARP000101577A patent/AR023401A1/en unknown
- 2000-04-07 US US09/545,456 patent/US6277831B1/en not_active Expired - Lifetime
- 2000-04-07 MY MYPI20001448A patent/MY120842A/en unknown
- 2000-04-21 TW TW089106263A patent/TWI254045B/en not_active IP Right Cessation
-
2001
- 2001-09-25 IL IL145647A patent/IL145647A/en not_active IP Right Cessation
- 2001-09-28 ZA ZA200107989A patent/ZA200107989B/en unknown
- 2001-10-02 NO NO20014792A patent/NO319836B1/en not_active IP Right Cessation
- 2001-10-08 HR HR20010725A patent/HRP20010725A2/en not_active Application Discontinuation
-
2002
- 2002-08-22 HK HK02106157.4A patent/HK1044537B/en not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20014792D0 (en) | With sugar residues substituted 1,4-benzothiazepine-1,1-dioxide derivatives, process for their preparation, drugs containing them and compounds and their use | |
DK1086113T3 (en) | Benzothiepine-1,1-dioxide derivatives, processes for their preparation, drugs containing these compounds and their use | |
DK1112251T3 (en) | Acetidine derivatives, their preparation and drugs containing these derivatives | |
NO20032733L (en) | Diphenyllazetidinone derivatives, process for their preparation, drugs containing these compounds and their use | |
DK1202965T3 (en) | Indole derivatives, processes for their preparation, pharmaceutical compositions containing them and their medical use | |
NO20024175D0 (en) | Acetidine derivatives, their preparation and pharmaceutical compounds containing the same | |
NO20021689D0 (en) | 5-ring heterocyclic derivatives, their preparation and use as drugs | |
NO20020687D0 (en) | 3 (5) -ureidopyrazole derivatives, process for their preparation and their use as antitumor agents | |
HUP0301315A3 (en) | Benzothiazole derivatives, process for their preparation, their use and pharmaceutical compositions containing them | |
NO20011216L (en) | Acetidine derivatives, their preparation and medicaments containing the compounds | |
NO924027D0 (en) | Heterobia Age Derivatives, Drugs Containing These Compounds, and Procedures for Their Preparation | |
IL144501A0 (en) | Epothilone derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same | |
NO20016038L (en) | Benzene derivatives, processes for their preparation and pharmaceutical compositions containing the same | |
NO20012057D0 (en) | 2-amino-thiazole derivatives, process for their preparation and use as antitumor agents | |
NO20016185D0 (en) | Bicyclic heterocycles, drugs containing these compounds, their use and method of preparation of | |
DK1674456T3 (en) | New 1,4-benzothiazepine-1,1-dioxide derivatives with improved properties, process for their preparation, drugs containing these compounds and their use | |
HUP0105313A3 (en) | Potassium salt of (s)-omeprazole, process for its preparation and pharmaceutical composition containing the same and its use | |
HUP0102292A3 (en) | Substituted thiazolidinedione derivative, process for its preparation and its pharmaceutical use | |
DK1117661T3 (en) | Propanolamine derivatives substituted with heterocyclic groups, process for their preparation, pharmaceutical preparations containing these compounds and their use | |
EE200100422A (en) | Epothilone derivatives, process for their preparation and pharmaceutical use | |
NO20015659L (en) | Purine derivatives, method of preparation and pharmaceutical compositions containing them | |
NO20016404D0 (en) | Naphthyridine derivatives, processes for their preparation, their use and pharmaceutical compositions comprising them | |
NO20013878L (en) | (1-Phenacy-3-phenyl-3-piperidylethyl) piperidine derivatives, process for their preparation and pharmaceutical preparations containing the same | |
NO20013141D0 (en) | Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical products containing them | |
HUP0203650A3 (en) | Heterocyclic derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |