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NO20013420L - ((Aminoiminometyl)amino)alkankarboksamider og deres anvendelser innen terapi - Google Patents

((Aminoiminometyl)amino)alkankarboksamider og deres anvendelser innen terapi

Info

Publication number
NO20013420L
NO20013420L NO20013420A NO20013420A NO20013420L NO 20013420 L NO20013420 L NO 20013420L NO 20013420 A NO20013420 A NO 20013420A NO 20013420 A NO20013420 A NO 20013420A NO 20013420 L NO20013420 L NO 20013420L
Authority
NO
Norway
Prior art keywords
aminoiminomethyl
therapy
amino
applications
carboxamides
Prior art date
Application number
NO20013420A
Other languages
English (en)
Norwegian (no)
Other versions
NO20013420D0 (no
Inventor
Gerard Moinet
Daniel Cravo
Didier Mesangeau
Liliane Doare
Micheline Kergoat
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20013420D0 publication Critical patent/NO20013420D0/no
Publication of NO20013420L publication Critical patent/NO20013420L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20013420A 1999-01-11 2001-07-10 ((Aminoiminometyl)amino)alkankarboksamider og deres anvendelser innen terapi NO20013420L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9900194A FR2788275B1 (fr) 1999-01-11 1999-01-11 ((aminoiminomethyl)amino) alcane carboxamides et leurs applications en therapeutique
PCT/EP1999/010468 WO2000042001A1 (en) 1999-01-11 1999-12-30 ((aminoiminomethyl) amino) alkanecarboxamides and their applications in therapy

Publications (2)

Publication Number Publication Date
NO20013420D0 NO20013420D0 (no) 2001-07-10
NO20013420L true NO20013420L (no) 2001-07-10

Family

ID=9540749

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013420A NO20013420L (no) 1999-01-11 2001-07-10 ((Aminoiminometyl)amino)alkankarboksamider og deres anvendelser innen terapi

Country Status (27)

Country Link
US (1) US6518458B1 (zh)
EP (1) EP1140803B1 (zh)
JP (1) JP4567889B2 (zh)
KR (1) KR100630291B1 (zh)
CN (1) CN1182109C (zh)
AR (1) AR022221A1 (zh)
AT (1) ATE252553T1 (zh)
AU (1) AU760147B2 (zh)
BR (1) BR9916858A (zh)
CA (1) CA2359454C (zh)
CZ (1) CZ20012482A3 (zh)
DE (1) DE69912315T2 (zh)
DK (1) DK1140803T3 (zh)
EE (1) EE200100363A (zh)
ES (1) ES2207325T3 (zh)
FR (1) FR2788275B1 (zh)
HK (1) HK1041689B (zh)
HU (1) HUP0200023A3 (zh)
ID (1) ID29586A (zh)
IL (1) IL144225A0 (zh)
NO (1) NO20013420L (zh)
NZ (1) NZ513467A (zh)
PT (1) PT1140803E (zh)
RU (1) RU2236401C2 (zh)
SK (1) SK285130B6 (zh)
WO (1) WO2000042001A1 (zh)
ZA (1) ZA200106606B (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101356935B1 (ko) 2004-05-05 2014-01-28 사일런스 테라퓨틱스 아게 지질, 지질 복합체 및 이들의 용도
EP2992902A1 (en) 2004-12-27 2016-03-09 Silence Therapeutics GmbH Lipid complexes coated with peg and their uses
TW200808705A (en) * 2006-06-15 2008-02-16 Sanofi Aventis Aryl- and heteroaryl-ethyl-acylguanidine derivatives, their preparation and their application in therapeutics
EP2546337A1 (en) * 2006-07-21 2013-01-16 Silence Therapeutics AG Means for inhibiting the expression of protein kinase 3
US8350077B2 (en) * 2008-12-24 2013-01-08 Vertex Closed Joint Stock Company Amides of creatine, method of their preparation, and remedy possessing a neuroprotective activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1153424A (en) * 1965-04-15 1969-05-29 Horlicks Ltd Pharmaceutical Compositions
US5654451B1 (en) * 1993-01-14 2000-02-22 Magainin Pharma Amino acids and peptides having modified c-terminals and modified n-terminals
JPH0841008A (ja) * 1994-07-29 1996-02-13 Ono Pharmaceut Co Ltd 一酸化窒素合成酵素阻害剤
CA2217550A1 (en) * 1996-10-22 1998-04-22 F. Hoffmann-La Roche Ag Cationic lipids for gene therapy
US6395713B1 (en) * 1997-07-23 2002-05-28 Ribozyme Pharmaceuticals, Inc. Compositions for the delivery of negatively charged molecules
DE19748697A1 (de) * 1997-11-04 1999-05-06 Basf Ag Verfahren zur Herstellung von substituierten Guanidinderivaten

Also Published As

Publication number Publication date
FR2788275B1 (fr) 2002-06-14
AR022221A1 (es) 2002-09-04
EP1140803A1 (en) 2001-10-10
SK9842001A3 (en) 2001-12-03
SK285130B6 (sk) 2006-07-07
IL144225A0 (en) 2002-05-23
NZ513467A (en) 2003-08-29
CA2359454A1 (en) 2000-07-20
ZA200106606B (en) 2002-11-11
ES2207325T3 (es) 2004-05-16
DE69912315T2 (de) 2004-08-05
DK1140803T3 (da) 2003-12-22
EP1140803B1 (en) 2003-10-22
PT1140803E (pt) 2004-03-31
US6518458B1 (en) 2003-02-11
FR2788275A1 (fr) 2000-07-13
BR9916858A (pt) 2001-12-04
JP4567889B2 (ja) 2010-10-20
EE200100363A (et) 2002-10-15
HK1041689A1 (en) 2002-07-19
HUP0200023A3 (en) 2003-04-28
NO20013420D0 (no) 2001-07-10
KR100630291B1 (ko) 2006-09-29
AU3044300A (en) 2000-08-01
CA2359454C (en) 2009-10-27
HUP0200023A2 (hu) 2002-05-29
CZ20012482A3 (cs) 2001-10-17
DE69912315D1 (de) 2003-11-27
CN1333747A (zh) 2002-01-30
WO2000042001A1 (en) 2000-07-20
JP2002534496A (ja) 2002-10-15
CN1182109C (zh) 2004-12-29
KR20010089822A (ko) 2001-10-08
HK1041689B (zh) 2005-09-02
AU760147B2 (en) 2003-05-08
RU2236401C2 (ru) 2004-09-20
ATE252553T1 (de) 2003-11-15
ID29586A (id) 2001-09-06

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application