[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

NL8520265A - Derivaten van vitamine d en werkwijzen voor het bereiden daarvan. - Google Patents

Derivaten van vitamine d en werkwijzen voor het bereiden daarvan. Download PDF

Info

Publication number
NL8520265A
NL8520265A NL8520265A NL8520265A NL8520265A NL 8520265 A NL8520265 A NL 8520265A NL 8520265 A NL8520265 A NL 8520265A NL 8520265 A NL8520265 A NL 8520265A NL 8520265 A NL8520265 A NL 8520265A
Authority
NL
Netherlands
Prior art keywords
gave
vitamin
ethyl acetate
mol
hexane
Prior art date
Application number
NL8520265A
Other languages
English (en)
Dutch (nl)
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NL8520265A publication Critical patent/NL8520265A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL8520265A 1984-10-04 1985-08-19 Derivaten van vitamine d en werkwijzen voor het bereiden daarvan. NL8520265A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US65754984A 1984-10-04 1984-10-04
US65754984 1984-10-04
PCT/US1985/001571 WO1986002078A1 (en) 1984-10-04 1985-08-19 Vitamin d derivatives and methods for preparing same
US8501571 1985-08-19

Publications (1)

Publication Number Publication Date
NL8520265A true NL8520265A (nl) 1986-09-01

Family

ID=24637652

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8520265A NL8520265A (nl) 1984-10-04 1985-08-19 Derivaten van vitamine d en werkwijzen voor het bereiden daarvan.

Country Status (13)

Country Link
EP (1) EP0197949A1 (da)
JP (3) JPS62500301A (da)
AU (2) AU582789B2 (da)
BE (1) BE903376A (da)
CH (1) CH672920A5 (da)
DE (2) DE3590488T (da)
DK (5) DK154290C (da)
FR (1) FR2571369B1 (da)
GB (2) GB2167070B (da)
IE (1) IE58104B1 (da)
IT (1) IT1190401B (da)
NL (1) NL8520265A (da)
WO (1) WO1986002078A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2711161B2 (ja) * 1988-04-21 1998-02-10 レオ・ファーマシューティカル・プロダクツ・リミテッド・エイ／エス（レーベンス・ケミスケ・ファブリック・プロデュクチオンスアクチーセルスカブ） 新規ビタミンｄ類似体
AU629831B2 (en) * 1988-04-29 1992-10-15 Wisconsin Alumni Research Foundation Side chain unsaturated 1 alpha-hydroxyvitamin d homologs for the treatment of leukemia
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
GB2229921B (en) * 1989-04-05 1992-12-16 Chugai Pharmaceutical Co Ltd Treatment for hyperparathyroidism with use of vitamin d derivatives
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5891865A (en) * 1996-10-04 1999-04-06 Wisconsin Alumni Research Foundation Treatment of arthritic disease induced by infectious agents
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
AU527805B2 (en) * 1978-07-27 1983-03-24 Research Institute For Medicine And Chemistry Inc. 1alpha, 1beta dihydroxy steroid-5-enes
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
DE3448412C2 (da) * 1983-05-09 1991-12-12 Wisconsin Alumni Res Found

Also Published As

Publication number Publication date
CH672920A5 (da) 1990-01-15
DK158991B (da) 1990-08-13
DK111188A (da) 1988-03-02
IE852443L (en) 1986-04-04
DK159389B (da) 1990-10-08
DK177489A (da) 1989-04-13
AU4776185A (en) 1986-04-17
DK158990C (da) 1991-01-21
FR2571369A1 (fr) 1986-04-11
JPH05178887A (ja) 1993-07-20
JPH0689022B2 (ja) 1994-11-09
DK154290C (da) 1989-03-28
DK15290D0 (da) 1990-01-19
DK260086A (da) 1986-06-03
DK15390A (da) 1990-01-19
JPS62500301A (ja) 1987-02-05
JPH0569103B2 (da) 1993-09-30
FR2571369B1 (fr) 1987-12-04
AU2761488A (en) 1989-06-08
IT8522359A0 (it) 1985-10-04
JPH0635475B2 (ja) 1994-05-11
DK154290B (da) 1988-10-31
WO1986002078A1 (en) 1986-04-10
DK111188D0 (da) 1988-03-02
DK158991C (da) 1991-01-21
GB2167070B (en) 1988-09-01
DK177489D0 (da) 1989-04-13
DK15290A (da) 1990-01-19
DE3590488C2 (da) 1992-10-01
GB8709579D0 (en) 1987-05-28
DK158989C (da) 1991-01-21
GB8524479D0 (en) 1985-11-06
DK260086D0 (da) 1986-06-03
EP0197949A1 (en) 1986-10-22
DK159389C (da) 1991-03-11
IE58104B1 (en) 1993-06-30
JPH05222089A (ja) 1993-08-31
GB2188932B (en) 1988-09-01
GB2188932A (en) 1987-10-14
GB2167070A (en) 1986-05-21
DE3590488T (de) 1986-10-09
AU605007B2 (en) 1991-01-03
DK158989B (da) 1990-08-13
BE903376A (fr) 1986-02-03
DK158990B (da) 1990-08-13
IT1190401B (it) 1988-02-16
AU582789B2 (en) 1989-04-13
DK15390D0 (da) 1990-01-19

Similar Documents

Publication Publication Date Title
US4448721A (en) Hydroxyvitamin D2 compounds and process for preparing same
US5414098A (en) Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US4358406A (en) 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same
US4769181A (en) 1,25-dihydroxyvitamin D2 compounds
US5532228A (en) Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
EP0296800B1 (en) Vitamin d3 derivatives
US4857518A (en) Hydroxylated 24-homo-vitamin D derivatives and methods for preparing same
US4248791A (en) 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
JPH0662664B2 (ja) Δ２２−コレスタ−５，７，２２−トリエン−１α，３β，２４−トリオール化合物
NL8420179A (nl) 23,23-difluro- 1 alfa, 25 dihydroxy-vitamine d3.
US5030772A (en) Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
JPS6253960A (ja) ビタミンｄ↓３の誘導体
NL8520265A (nl) Derivaten van vitamine d en werkwijzen voor het bereiden daarvan.
NL8420327A (nl) Isomeren van hydroxyvitamine d2.
EP0236346B1 (en) 26,26,26,27,27-pentafluoro-1-alpha-hydroxy-27-methoxyvitamin d3
WO1989010352A1 (en) SIDE CHAIN UNSATURATED 1alpha-HYDROXYVITAMIN D HOMOLOGS
CA2058637A1 (en) Side-chain homologous vitamin d derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
US5354744A (en) Side chain unsaturated 1 alpha-hydroxyvitamin D analogs
US5036061A (en) Process for the preparation of 1 alpha,25-dihydroxylated vitamin D2 and related compounds
EP0154627A1 (en) 23,23-difluoro-25-hydroxy-vitamin d 3? and process for preparing same
JPH0319240B2 (da)
FR2560597A1 (fr) Produits analogues de la 1a-hydroxyvitamine d2, leur procede de preparation et compositions pharmaceutiques les renfermant
KR20010102330A (ko) 3-메틸 비타민 ｄ 유도체
FR2550789A1 (fr) 23,23-difluoro-25-hydroxy- et 1a,25-dihydroxy-vitamine d3
DeLuca et al. 1, 25-dihydroxyvitamin D 2 compounds