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NL7614389A - Werkwijze ter bereiding van een prostaglandine. - Google Patents

Werkwijze ter bereiding van een prostaglandine.

Info

Publication number
NL7614389A
NL7614389A NL7614389A NL7614389A NL7614389A NL 7614389 A NL7614389 A NL 7614389A NL 7614389 A NL7614389 A NL 7614389A NL 7614389 A NL7614389 A NL 7614389A NL 7614389 A NL7614389 A NL 7614389A
Authority
NL
Netherlands
Prior art keywords
prostaglandin
preparing
Prior art date
Application number
NL7614389A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NL7614389A publication Critical patent/NL7614389A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02Magnesium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids
    • C07F9/4059Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL7614389A 1975-12-29 1976-12-24 Werkwijze ter bereiding van een prostaglandine. NL7614389A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64527675A 1975-12-29 1975-12-29

Publications (1)

Publication Number Publication Date
NL7614389A true NL7614389A (nl) 1977-07-01

Family

ID=24588384

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7614389A NL7614389A (nl) 1975-12-29 1976-12-24 Werkwijze ter bereiding van een prostaglandine.

Country Status (18)

Country Link
US (4) US4081478A (nl)
JP (1) JPS5283351A (nl)
AU (1) AU502349B2 (nl)
BE (1) BE849963A (nl)
CA (1) CA1077473A (nl)
CH (1) CH629747A5 (nl)
DE (1) DE2658207A1 (nl)
ES (1) ES454181A1 (nl)
FR (1) FR2336924A1 (nl)
GB (2) GB1554042A (nl)
HU (1) HU178365B (nl)
IL (1) IL50997A (nl)
MX (1) MX4940E (nl)
NL (1) NL7614389A (nl)
PL (1) PL116421B1 (nl)
SE (1) SE7614584L (nl)
SU (1) SU731895A3 (nl)
ZA (1) ZA767416B (nl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048058A (en) * 1975-08-13 1977-09-13 Standard Oil Company (Indiana) Methods to be used in reforming processes employing multi-metallic catalysts
US4267315A (en) * 1979-05-01 1981-05-12 The Upjohn Company 2-Decarboxy-2-aminomethyl-11a-methano-TXA2 compounds
US4292445A (en) * 1980-04-28 1981-09-29 The Upjohn Company Amide and sulfonamide derivatives of 2-decarboxy-2-aminomethyl-PG-type compounds
CA1241324A (en) 1984-03-08 1988-08-30 Paul A. Aristoff Interphenylene carbacyclin derivatives
JPH0121948Y2 (nl) * 1985-03-29 1989-06-29
US5270049A (en) * 1990-11-09 1993-12-14 Allergan, Inc. 2-decarboxyl-2-aminoalkyl-prostaglandins as ocular hypotensives
HU223068B1 (hu) * 1995-12-20 2004-03-01 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás PGE1 prosztanoid előállítására
US9241918B2 (en) 2005-03-16 2016-01-26 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
EP2454227B1 (en) 2009-07-13 2020-08-19 Patheon API Services Inc. Synthesis of prostanoids
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
HUP1000284A3 (en) * 2010-06-01 2012-08-28 Avidin Kft Use of derivatives of pgf1-alpha for preparation of medicament for reducing inflammation
CN105592851A (zh) 2013-09-30 2016-05-18 帕西昂Api服务公司 利用复分解反应的前列腺素和前列腺素中间体的新合成途径
CN104860860B (zh) * 2015-04-29 2017-09-19 东北制药集团股份有限公司 一种卡前列酯的纯化制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2166971A (en) * 1932-09-14 1939-07-25 Ig Farbenindustrie Ag Production of amines
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
US3647804A (en) * 1970-02-27 1972-03-07 Upjohn Co Cycloalkanecarboxamides
US3852296A (en) * 1971-07-16 1974-12-03 Richardson Merrell Spa Mannich bases of cyclopentanones and cyclopent-2-enones and process of preparing the same
US3987087A (en) * 1971-07-29 1976-10-19 The Upjohn Company Phenyl-substituted prostaglandin-f type analogs
US3954741A (en) * 1972-06-07 1976-05-04 Pfizer Inc. N-substituted prostaglandin carboxamides
US3987085A (en) * 1972-09-15 1976-10-19 The Upjohn Company 8β,11β,12α-PGF2.sub.α compounds

Also Published As

Publication number Publication date
FR2336924B1 (nl) 1984-08-17
PL116421B1 (en) 1981-06-30
GB1554042A (en) 1979-10-17
JPS5283351A (en) 1977-07-12
HU178365B (en) 1982-04-28
MX4940E (es) 1983-01-10
FR2336924A1 (fr) 1977-07-29
JPS5744666B2 (nl) 1982-09-22
SU731895A3 (ru) 1980-04-30
AU502349B2 (en) 1979-07-19
US4073808A (en) 1978-02-14
ZA767416B (en) 1977-11-30
DE2658207A1 (de) 1977-07-07
CA1077473A (en) 1980-05-13
SE7614584L (sv) 1977-06-30
US4085139A (en) 1978-04-18
BE849963A (fr) 1977-06-29
US4122282A (en) 1978-10-24
IL50997A (en) 1982-05-31
GB1554041A (en) 1979-10-17
IL50997A0 (en) 1977-01-31
CH629747A5 (de) 1982-05-14
US4081478A (en) 1978-03-28
AU2039676A (en) 1978-06-15
ES454181A1 (es) 1977-12-16

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed