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NL7503553A - 16-geoxygeneerde prostaanzuurderivaten. - Google Patents

16-geoxygeneerde prostaanzuurderivaten.

Info

Publication number
NL7503553A
NL7503553A NL7503553A NL7503553A NL7503553A NL 7503553 A NL7503553 A NL 7503553A NL 7503553 A NL7503553 A NL 7503553A NL 7503553 A NL7503553 A NL 7503553A NL 7503553 A NL7503553 A NL 7503553A
Authority
NL
Netherlands
Prior art keywords
oxygenated
acid derivatives
prostanic acid
prostanic
derivatives
Prior art date
Application number
NL7503553A
Other languages
English (en)
Other versions
NL183294B (nl
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NL7503553A publication Critical patent/NL7503553A/nl
Publication of NL183294B publication Critical patent/NL183294B/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
NLAANVRAGE7503553,A 1974-03-26 1975-03-25 Werkwijze voor de bereiding van een 15-deoxy-16-geoxygeneerde prostaanzuurderivaten bevattend geneesmiddel met anti-maagsapafscheidende werking en voor een prostaanzuurderivaat, geschikt voor gebruik bij deze werkwijze. NL183294B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/454,913 US3965143A (en) 1974-03-26 1974-03-26 16-Oxygenated prostanoic acid derivatives

Publications (2)

Publication Number Publication Date
NL7503553A true NL7503553A (nl) 1975-09-30
NL183294B NL183294B (nl) 1988-04-18

Family

ID=23806587

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE7503553,A NL183294B (nl) 1974-03-26 1975-03-25 Werkwijze voor de bereiding van een 15-deoxy-16-geoxygeneerde prostaanzuurderivaten bevattend geneesmiddel met anti-maagsapafscheidende werking en voor een prostaanzuurderivaat, geschikt voor gebruik bij deze werkwijze.
NL930058C NL930058I2 (nl) 1974-03-26 1993-06-11 Werkwijze voor de bereiding van een 15-deoxy-16-geoxygeneerde prostaanzuurafscheidende werking en voor een prostaanzuurderivaat, geschikt voor gebruikbij deze werkwijze.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL930058C NL930058I2 (nl) 1974-03-26 1993-06-11 Werkwijze voor de bereiding van een 15-deoxy-16-geoxygeneerde prostaanzuurafscheidende werking en voor een prostaanzuurderivaat, geschikt voor gebruikbij deze werkwijze.

Country Status (25)

Country Link
US (1) US3965143A (nl)
JP (1) JPS5855142B2 (nl)
AR (1) AR207355A1 (nl)
AT (1) AT351684B (nl)
BE (1) BE827127A (nl)
CA (1) CA1040197A (nl)
CH (1) CH613443A5 (nl)
DE (1) DE2513212C2 (nl)
DK (1) DK128075A (nl)
EG (1) EG12063A (nl)
ES (1) ES436043A1 (nl)
FI (1) FI63747C (nl)
FR (1) FR2274289A1 (nl)
GB (1) GB1492426A (nl)
HU (1) HU174973B (nl)
IE (1) IE41328B1 (nl)
IL (1) IL46919A (nl)
NL (2) NL183294B (nl)
NO (1) NO146200C (nl)
OA (1) OA04910A (nl)
PH (1) PH16276A (nl)
PL (1) PL100838B1 (nl)
SE (1) SE420199B (nl)
YU (1) YU39735B (nl)
ZA (1) ZA751391B (nl)

Families Citing this family (67)

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US4143051A (en) * 1972-07-13 1979-03-06 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandins
US4293704A (en) * 1975-09-25 1981-10-06 American Cyanamid Company Novel 2-substituted-3,4-epoxycyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones
US4107441A (en) * 1973-06-15 1978-08-15 American Cyanamid Company Novel 16 hydroxy 15-deoxy-5-cis-prostenoic acids and esters
US4060691A (en) * 1974-03-26 1977-11-29 G. D. Searle & Co. 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters
US4190596A (en) * 1976-07-19 1980-02-26 American Cyanamid Company Various 15-deoxy-16-hydroxy-16-ethynyl and 16-ethynylsubstituted prostaglandins
US4192950A (en) * 1976-07-19 1980-03-11 American Cyanamid Company 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4328358A (en) * 1976-07-19 1982-05-04 American Cyanamid Company 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4191699A (en) * 1976-07-19 1980-03-04 American Cyanamid Company Various- 15-deoxy-16-hydroxy-16-ethynyl and 16-ethynylsubstituted prostaglandins
US4730065A (en) * 1976-07-19 1988-03-08 American Cyanamid Company 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4429148A (en) 1976-07-19 1984-01-31 American Cyanamid Company 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4061670A (en) * 1976-07-19 1977-12-06 American Cyanamid Company 15-Deoxy-16-hydroxy-16-vinyl and cyclopropyl substituted prostanoic acids and congeners
AU3437478A (en) * 1977-03-30 1979-09-27 American Cyanamid Co Prostanoic acids and congeners
US4281153A (en) * 1977-08-01 1981-07-28 American Cyanamid 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
GB2006186A (en) * 1977-08-29 1979-05-02 American Cyanamid Co 15-Deoxy-16-substituted prostanoic acids
GB2009162A (en) * 1977-12-05 1979-06-13 American Cyanamid Co Prostanoic acids and congeners
AU529836B2 (en) * 1977-12-05 1983-06-23 American Cyanamid Company Prostaglandin analog
US4742080A (en) * 1978-02-23 1988-05-03 Miles Laboratories, Inc. Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters
US4132738A (en) * 1978-02-23 1979-01-02 Miles Laboratories, Inc. Preparation of 15-deoxy-16-hydroxyprostaglandins
US4833157A (en) * 1978-02-23 1989-05-23 Miles Inc. Methods of inhibitng gastric secretion with prostaglandin derivatives
US4239899A (en) * 1979-09-13 1980-12-16 American Cyanamid Company Various 15-deoxy-16-hydroxy-16-ethynyl and 16-ethynylsubstituted prostaglandins
US4271314A (en) * 1979-11-28 1981-06-02 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives
US4322543A (en) * 1979-11-28 1982-03-30 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives
US4310700A (en) * 1980-04-03 1982-01-12 American Cyanamid Company 1-Hydroxylmethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives
US4289910A (en) * 1980-04-03 1981-09-15 American Cyanamid Company 1-Hydroxymethyl-prosten-1-ol derivatives
US4291175A (en) * 1980-04-03 1981-09-22 American Cyanamid Company 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives
US4288630A (en) * 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11,15-dihydroxy-prosten-1-ol-derivatives
US4291174A (en) * 1980-04-03 1981-09-22 American Cyanamid Company 1-Hydroxymethyl-15-hydroxy-prosten-1-ol derivatives
US4288633A (en) * 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11-deoxy-16-hydroxy-prosten-1-ol-derivatives
US4288632A (en) * 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11,16-dihydroxy-prosten-1-ol derivatives
US4288629A (en) * 1980-04-03 1981-09-08 American Cyanamid Company 1-Hydroxymethyl-11-deoxy-15-hydroxy-prosten-1-ol-derivatives
US4301146A (en) * 1980-07-29 1981-11-17 G. D. Searle & Co. Stabilization of 16-oxygenated prostanoic acid derivatives
US4399290A (en) * 1980-09-22 1983-08-16 E. I. Du Pont De Nemours And Company Optically active tert-alkyl 7-(2-oxo-5-carbonyloxypyrrolidinyl)heptanoates
US4459310A (en) * 1983-06-27 1984-07-10 G.D. Searle & Co. Method for cholesterol lowering
US4499296A (en) * 1983-11-14 1985-02-12 G. D. Searle & Co. Omega cycloalkyl prostaglandins
US4754059A (en) * 1984-11-07 1988-06-28 G. D. Searle & Co. Omega cycloalkyl prostaglandins
US4847293A (en) * 1985-11-25 1989-07-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4820728A (en) * 1985-11-25 1989-04-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4683328A (en) * 1985-11-25 1987-07-28 G. D. Searle & Co. Tetraenyl prostaglandins
US4785124A (en) * 1987-06-08 1988-11-15 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US5011958A (en) * 1987-06-08 1991-04-30 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US4777275A (en) * 1987-06-09 1988-10-11 G. D. Searle & Co. Process of preparing higher order cuprate complexes
US5252763A (en) * 1990-04-17 1993-10-12 G. D. Searle & Co. Process for preparing prostaglandin analogs
US5055604A (en) * 1990-04-17 1991-10-08 G. D. Searle & Co. Process for preparing prostaglandin analogs using organozirconium compounds
WO1991016896A1 (en) * 1990-05-03 1991-11-14 G.D. Searle & Co. Pharmaceutical composition for use in treating pain
US5232704A (en) * 1990-12-19 1993-08-03 G. D. Searle & Co. Sustained release, bilayer buoyant dosage form
US5157052A (en) * 1990-12-27 1992-10-20 Monsanto Company Method for inhibiting ige production
US5218139A (en) * 1990-12-27 1993-06-08 G. D. Searle & Co. Method for inhibiting IgE production
US5324746A (en) * 1993-02-12 1994-06-28 Mckee Rex N Method of treating damaged mucosal and epithelial tissues with misoprostol
EP0807634B1 (en) * 1996-05-17 2003-04-09 TORCAN CHEMICAL Ltd Misoprostol, process for its preparation using an organometallic cuprate complex
US5684177A (en) * 1996-05-17 1997-11-04 Torcan Chemical Ltd. Misoprostol
WO1997045114A1 (en) * 1996-05-30 1997-12-04 Lysis Corporation The treatment of vascular disease with prostaglandins via a sustained-release dermal patch
US5994399A (en) * 1997-03-27 1999-11-30 Mckee; Rex N. Method of regenerating collagen-containing tissues with misoprostol
US6030959A (en) * 1997-04-04 2000-02-29 Monsanto Company Gastro-specific prodrugs
WO1999002147A1 (en) 1997-07-09 1999-01-21 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
EP0896823B1 (en) * 1997-07-15 2002-09-25 Development Center For Biotechnology Improved stabilization of Misoprostol
CA2477088A1 (en) 2002-02-22 2003-10-02 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
EP1563845A4 (en) * 2002-10-10 2008-02-20 Univ Kyoto REMEDIES FOR ALLERGIC DISEASES
DK2465537T3 (en) 2002-10-10 2016-09-19 Ono Pharmaceutical Co MICROSPHERE INCLUDING ONO-1301
EP2422814A1 (en) 2003-07-25 2012-02-29 Ono Pharmaceutical Co., Ltd. Remedy for cartilage-related diseases
US7241746B2 (en) * 2003-08-06 2007-07-10 Regena Therapeutics, Lc Method and composition for treating periodontal disease
US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
US20100010046A1 (en) * 2006-06-12 2010-01-14 Ironwood Pharmaceuticals, Inc. Pharmaceutical formulation for parenteral administration
US20150272874A1 (en) 2012-10-29 2015-10-01 Cardio Incorporated Pulmonary disease-specific therapeutic agent
US9968716B2 (en) 2013-10-15 2018-05-15 Ono Pharmaceutical Co., Ltd. Drug-eluting stent graft
HU231185B1 (hu) 2017-07-11 2021-07-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Eljárás Misoprostol előállítására és tisztítására
CN108753898A (zh) * 2018-04-09 2018-11-06 深圳市祥根生物科技有限公司 一种米索前列醇酸的制备方法及其用途

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US3812172A (en) * 1970-05-04 1974-05-21 Upjohn Co 15-methyl and 15-ethyl dihydro-pge1
ZA72646B (en) * 1971-03-11 1973-09-26 Upjohn Co Prostaglandin analogs
CA1045131A (en) * 1972-07-24 1978-12-26 Middleton B. Floyd (Jr.) Derivatives of 9-hydroxy-13-trans-prostenoic acid

Also Published As

Publication number Publication date
DE2513212A1 (de) 1975-10-09
SE420199B (sv) 1981-09-21
CH613443A5 (nl) 1979-09-28
PL100838B1 (pl) 1978-11-30
IL46919A0 (en) 1975-05-22
GB1492426A (en) 1977-11-16
US3965143A (en) 1976-06-22
HU174973B (hu) 1980-04-28
NO751039L (nl) 1975-09-29
NL930058I1 (nl) 1993-09-01
BE827127A (fr) 1975-09-25
AT351684B (de) 1979-08-10
YU39735B (en) 1985-04-30
IL46919A (en) 1979-12-30
ATA227375A (de) 1979-01-15
ES436043A1 (es) 1977-01-16
NL930058I2 (nl) 1994-02-16
FI63747C (fi) 1983-08-10
NO146200C (no) 1982-08-18
SE7503431L (nl) 1975-09-29
AU7947175A (en) 1976-09-30
YU73575A (en) 1982-02-28
DK128075A (nl) 1975-09-27
PH16276A (en) 1983-08-26
NO146200B (no) 1982-05-10
CA1040197A (en) 1978-10-10
FR2274289B1 (nl) 1979-06-29
OA04910A (fr) 1980-10-31
FI63747B (fi) 1983-04-29
ZA751391B (en) 1976-10-27
EG12063A (en) 1978-09-30
JPS50135059A (nl) 1975-10-25
FI750899A (nl) 1975-09-27
FR2274289A1 (fr) 1976-01-09
IE41328B1 (en) 1979-12-05
IE41328L (en) 1975-09-26
JPS5855142B2 (ja) 1983-12-08
DE2513212C2 (de) 1986-03-27
NL183294B (nl) 1988-04-18
AR207355A1 (es) 1976-09-30

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
SNR Assignments of patents or rights arising from examined patent applications

Owner name: GDS NEWCO INC.

TNT Modifications of names of proprietors of patents or applicants of examined patent applications

Owner name: G.D. SEARLE & CO.

AC1 Application for a supplementary protection certificate

Free format text: 930058, 930611

KC1 Grant of a supplementary protection certificate

Free format text: 930058, 950325, EXPIRES:20000324

V4 Discontinued because of reaching the maximum lifetime of a patent
AC1 Application for a supplementary protection certificate

Free format text: 0930058, 930611