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NI200900155A - COMPUESTOS DE 2-AMINO PIRIMIDINA. Caso: PC 33441A - Google Patents

COMPUESTOS DE 2-AMINO PIRIMIDINA. Caso: PC 33441A

Info

Publication number
NI200900155A
NI200900155A NI200900155A NI200900155A NI200900155A NI 200900155 A NI200900155 A NI 200900155A NI 200900155 A NI200900155 A NI 200900155A NI 200900155 A NI200900155 A NI 200900155A NI 200900155 A NI200900155 A NI 200900155A
Authority
NI
Nicaragua
Prior art keywords
case
pyrimidine compounds
amino pyrimidine
compounds
amino
Prior art date
Application number
NI200900155A
Other languages
English (en)
Inventor
John Bennett Michael
Huang Buwen
Kung Pei-Pei
Jialun Meng Jerry
Ninkovic Sacha
Raymond Zehnder Luke
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NI200900155A publication Critical patent/NI200900155A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula (I), y sales farmacéuticamente aceptables de los mismos, a su síntesis y a su uso como inhibidores de HSP-90.
NI200900155A 2007-02-06 2009-08-05 COMPUESTOS DE 2-AMINO PIRIMIDINA. Caso: PC 33441A NI200900155A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88843307P 2007-02-06 2007-02-06
US2066108P 2008-01-11 2008-01-11

Publications (1)

Publication Number Publication Date
NI200900155A true NI200900155A (es) 2010-06-30

Family

ID=39367692

Family Applications (1)

Application Number Title Priority Date Filing Date
NI200900155A NI200900155A (es) 2007-02-06 2009-08-05 COMPUESTOS DE 2-AMINO PIRIMIDINA. Caso: PC 33441A

Country Status (22)

Country Link
US (1) US20100093696A1 (es)
EP (1) EP2118111B1 (es)
JP (1) JP4523073B2 (es)
KR (1) KR20090116789A (es)
AP (1) AP2009004954A0 (es)
AT (1) ATE502944T1 (es)
AU (1) AU2008212645A1 (es)
BR (1) BRPI0807165A2 (es)
CA (1) CA2677365A1 (es)
CO (1) CO6220971A2 (es)
CR (1) CR10963A (es)
CU (1) CU20090141A7 (es)
DE (1) DE602008005715D1 (es)
DO (1) DOP2009000200A (es)
EA (1) EA200970669A1 (es)
EC (1) ECSP099565A (es)
IL (1) IL200169A0 (es)
MA (1) MA31170B1 (es)
MX (1) MX2009008386A (es)
NI (1) NI200900155A (es)
TN (1) TN2009000329A1 (es)
WO (1) WO2008096218A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2732922A1 (en) 2008-08-13 2010-02-18 Pfizer Inc. 2-amino pyrimidine compounds as potent hsp-90 inhibitors
GB0907284D0 (en) 2009-04-28 2009-06-10 Queen Mary & Westfield College Compounds for inducing cellular apoptosis
AR077405A1 (es) 2009-07-10 2011-08-24 Sanofi Aventis Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer
FR2949467B1 (fr) 2009-09-03 2011-11-25 Sanofi Aventis Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation
KR20130005263A (ko) 2009-12-30 2013-01-15 아르퀼 인코포레이티드 치환된 나프탈레닐-피리미딘 화합물
EP2752201A1 (en) * 2013-01-04 2014-07-09 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. C-terminal HSP90 inhibitors to treat pituitary adenomas
WO2014149819A1 (en) 2013-03-14 2014-09-25 Kalyra Pharmaceuticals, Inc. Bicyclic analgesic compounds
CN105814013A (zh) 2013-12-12 2016-07-27 卡利拉制药公司 双环烷基化合物及合成
KR102401840B1 (ko) 2014-03-07 2022-05-25 리커리엄 아이피 홀딩스, 엘엘씨 프로펠란 유도체 및 합성
EP3154547B1 (en) 2014-06-13 2023-06-07 Yuma Therapeutics, Inc. Pyrimidine compounds and methods using the same
CN106999451B (zh) 2014-09-17 2021-04-02 里科瑞尔姆Ip控股有限责任公司 双环化合物
US10227029B2 (en) * 2015-08-07 2019-03-12 Kawasaki Jukogyo Kabushiki Kaisha Container holder attached to utility vehicle
NZ759268A (en) 2017-05-15 2022-07-01 Recurium Ip Holdings Llc Bicyclo[1.1.1]pentyl compounds as analgesics
WO2020243457A1 (en) * 2019-05-29 2020-12-03 Viogen Biosciences, Llc Compounds and therapeutic uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
AU2001239770B2 (en) 2000-02-15 2006-01-05 Pharmacia & Upjohn Company Pyrrole substituted 2-indolinone protein kinase inhibitors
CA2473510A1 (en) * 2002-01-23 2003-07-31 Bayer Pharmaceuticals Corporation Pyrimidine derivatives as rho-kinase inhibitors
US7312330B2 (en) * 2003-12-24 2007-12-25 Renovis, Inc. Bicycloheteroarylamine compounds as ion channel ligands and uses thereof
JP2008534609A (ja) * 2005-03-30 2008-08-28 コンフォーマ・セラピューティクス・コーポレイション Ｈｓｐ９０阻害剤としてのアルキニルピロロピリミジンおよび関連類似体

Also Published As

Publication number Publication date
CU20090141A7 (es) 2011-04-26
AU2008212645A1 (en) 2008-08-14
TN2009000329A1 (fr) 2010-12-31
EP2118111B1 (en) 2011-03-23
ECSP099565A (es) 2009-09-29
CA2677365A1 (en) 2008-08-14
DE602008005715D1 (de) 2011-05-05
JP2010518066A (ja) 2010-05-27
US20100093696A1 (en) 2010-04-15
CO6220971A2 (es) 2010-11-19
EP2118111A1 (en) 2009-11-18
ATE502944T1 (de) 2011-04-15
MA31170B1 (fr) 2010-02-01
MX2009008386A (es) 2009-10-16
CR10963A (es) 2009-08-27
DOP2009000200A (es) 2009-09-15
JP4523073B2 (ja) 2010-08-11
BRPI0807165A2 (pt) 2014-05-06
AP2009004954A0 (en) 2009-08-31
EA200970669A1 (ru) 2010-02-26
KR20090116789A (ko) 2009-11-11
WO2008096218A1 (en) 2008-08-14
IL200169A0 (en) 2010-04-15

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