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MY6600061A - Method for making 2, 4-diamino-5-arylmethyl pyrimidines and intermediates therefor - Google Patents

Method for making 2, 4-diamino-5-arylmethyl pyrimidines and intermediates therefor

Info

Publication number
MY6600061A
MY6600061A MY6600061A MY6600061A MY6600061A MY 6600061 A MY6600061 A MY 6600061A MY 6600061 A MY6600061 A MY 6600061A MY 6600061 A MY6600061 A MY 6600061A MY 6600061 A MY6600061 A MY 6600061A
Authority
MY
Malaysia
Prior art keywords
arylmethyl
pyrimidines
diamino
making
intermediates therefor
Prior art date
Application number
MY6600061A
Other languages
English (en)
Inventor
Malcolm Hood Harold
Wellcome Foundation Limited The
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27258299&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY6600061(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of MY6600061A publication Critical patent/MY6600061A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
MY6600061A 1959-09-03 1966-12-31 Method for making 2, 4-diamino-5-arylmethyl pyrimidines and intermediates therefor MY6600061A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB3010259A GB957797A (en) 1959-09-03 1959-09-03 Method for making 2,4-diamino-5-arylmethylpyrimidines and intermediates therefor
GB3956059 1959-11-20
GB2410160 1960-07-11

Publications (1)

Publication Number Publication Date
MY6600061A true MY6600061A (en) 1966-12-31

Family

ID=27258299

Family Applications (1)

Application Number Title Priority Date Filing Date
MY6600061A MY6600061A (en) 1959-09-03 1966-12-31 Method for making 2, 4-diamino-5-arylmethyl pyrimidines and intermediates therefor

Country Status (7)

Country Link
AT (1) AT230379B (xx)
CH (1) CH418338A (xx)
DE (2) DE1445176C3 (xx)
FI (1) FI42960B (xx)
GB (1) GB957797A (xx)
IT (1) IT1061608B (xx)
MY (1) MY6600061A (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
US3855265A (en) * 1969-03-06 1974-12-17 Burroughs Wellcome Co 5-benzyl pyrimidines intermediates therefore, and method
US3991050A (en) * 1969-03-06 1976-11-09 Burroughs Wellcome Co. Preparation of β-Amino-α-benzylacrylonitriles
US3950378A (en) * 1969-03-06 1976-04-13 Burroughs Wellcome Co. Preparation of β-anilino-α-benzylacrylonitriles
GB1261455A (en) * 1969-03-06 1972-01-26 Burroughs Wellcome Co Improvements in or relating to substituted acrylonitriles
US3998814A (en) 1969-03-06 1976-12-21 Burroughs Wellcome Co. Process for preparing β-amino-α-benzylacrylonitriles
US3852276A (en) * 1969-03-06 1974-12-03 Burroughs Wellcome Co 5-benzyl pyrimidines intermediate therefore, and method
US4052553A (en) * 1969-03-06 1977-10-04 Burroughs Wellcome Co. 5-benzyl pyrimidines intermediates therefore, and method
DE2065367C2 (de) * 1969-03-06 1985-04-04 The Wellcome Foundation Ltd., London Verfahren zur Herstellung von 2,4- Diamino-5-benzylpyrimidinen
DE2051871A1 (en) * 1969-05-16 1971-11-18 The Wellcome Foundation Ltd., London Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents
BR6915082D0 (pt) 1969-05-16 1973-03-08 Wellcome Found Processo de preparacao de benzil-pirimidinas
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
US4039543A (en) 1974-12-24 1977-08-02 Hoffmann-La Roche Inc. Benzylpyrimidines
CH624943A5 (xx) * 1977-02-04 1981-08-31 Hoffmann La Roche
DE2720771C3 (de) 1977-05-09 1979-11-29 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-Diamino-5-(33-dimethoxy-4thioalkyl-benzyD-pyrimidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0046856A3 (de) * 1980-08-29 1982-07-28 Hüls Troisdorf Aktiengesellschaft Verfahren zur Herstellung von 4-Amino-2-mercaptopyrimidinen
AT384023B (de) * 1980-11-11 1987-09-25 Wellcome Found Verfahren zur herstellung von neuen 2,4-diamino-5-(subst.)pyrimidinen und deren salzen, n-oxiden und n-acylderivaten
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
HU186413B (en) * 1981-06-26 1985-07-29 Egyt Gyogyszervegyeszeti Gyar Process for producing 2,4-diamino-5-bracket-3-comma above,4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine
HU187370B (en) * 1981-06-26 1985-12-28 Egyt Gyogyszervegyeszeti Gyar Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine
DK190983A (da) * 1982-05-01 1983-11-02 Wellcome Found 2,4-diamino-5-(substituerede)pyrimidiner, fremgangsmaade til deres fremstilling og mellemprodukter derfor
US4587341A (en) * 1982-05-07 1986-05-06 Burroughs Wellcome Co. 2,4-diamino-5-(1,2,3,4-tetrahydro-(substituted or unsubstituted)-6-quinolylmethyl)pyrimidines, useful as antimicrobials
DE3603577A1 (de) * 1986-02-06 1987-08-13 Joachim K Prof Dr Seydel Neue substituierte 2,4-diamino-5-benzylpyrimidine, deren herstellung und deren verwendung als arzneimittel mit antibakterieller wirksamkeit
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.

Also Published As

Publication number Publication date
CH418338A (de) 1966-08-15
AT230379B (de) 1963-12-10
DE1445176A1 (de) 1968-10-17
IT1061608B (it) 1983-04-30
DE1303727B (de) 1976-02-05
GB957797A (en) 1964-05-13
DE1445176B2 (de) 1973-09-06
FI42960B (xx) 1970-09-02
DE1445176C3 (de) 1974-04-25

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