MXPA05012823A - Metodo y aparato para la mejora de absorcion cutanea y el suministro transdermico de droga de lidocaina y/u otras drogas. - Google Patents
Metodo y aparato para la mejora de absorcion cutanea y el suministro transdermico de droga de lidocaina y/u otras drogas.Info
- Publication number
- MXPA05012823A MXPA05012823A MXPA05012823A MXPA05012823A MXPA05012823A MX PA05012823 A MXPA05012823 A MX PA05012823A MX PA05012823 A MXPA05012823 A MX PA05012823A MX PA05012823 A MXPA05012823 A MX PA05012823A MX PA05012823 A MXPA05012823 A MX PA05012823A
- Authority
- MX
- Mexico
- Prior art keywords
- skin
- patient
- solution
- pads
- lidocaine
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 229960004194 lidocaine Drugs 0.000 title abstract 3
- 230000037384 skin absorption Effects 0.000 title 1
- 231100000274 skin absorption Toxicity 0.000 title 1
- 238000013271 transdermal drug delivery Methods 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 3
- 239000000017 hydrogel Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H9/00—Pneumatic or hydraulic massage
- A61H9/005—Pneumatic massage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
- A61H23/0254—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with rotary motor
- A61H23/0263—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with rotary motor using rotating unbalanced masses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/002—Using electric currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H7/00—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
- A61H7/007—Kneading
- A61H7/008—Suction kneading
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A61N1/0416—Anode and cathode
- A61N1/0424—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
- A61H2201/105—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy with means for delivering media, e.g. drugs or cosmetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0008—Destruction of fat cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rehabilitation Therapy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Percussion Or Vibration Massage (AREA)
- Electrotherapy Devices (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un metodo de tratamiento para el suministro de lidocaina u otro tipo de droga de tratamiento cutaneo a la piel de un paciente, incluye aplicar rafagas electricas de impulsos sobre la piel del paciente mediante electrodos proporcionados en una cabeza de una sonda que se coloca contra la piel del paciente. El metodo de tratamiento incluye tambien aplicar vibraciones mecanicas de una misma frecuencia y fase como rafagas de impulsos sobre la piel del paciente mediante un elemento vibrante proporcionado en la cabeza de la sonda. Al mismo tiempo que se realizan los dos pasos anteriores, el metodo de tratamiento incluye proporcionar, entre los electrodos y la piel del paciente, al menos dos almohadillas de absorcion de solucion aisladas electricamente una de otra y cada una de las dos almohadillas de absorcion de solucion en contacto electrico con uno o mas de los electrodos en la cabeza de la sonda. Al menos una de las dos almohadillas de absorcion de solucion se remoja con lidocaina u otro tipo de droga de tratamiento cutaneo y la otra de las dos almohadillas de absorcion de solucion se remoja con una solucion fisiologica conductora. Las almohadillas pueden ser almohadillas de gasa o almohadillas de hidrogel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/448,468 US6980854B2 (en) | 2001-04-06 | 2003-05-30 | Method and apparatus for skin absorption enhancement and transdermal drug delivery of lidocaine and/or other drugs |
PCT/IB2004/001760 WO2004105868A1 (en) | 2003-05-30 | 2004-05-27 | Method and apparatus for skin absorption enhancement and transdermal drug delivery of lidocaine and/or other drugs |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05012823A true MXPA05012823A (es) | 2006-02-22 |
Family
ID=33489403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05012823A MXPA05012823A (es) | 2003-05-30 | 2004-05-27 | Metodo y aparato para la mejora de absorcion cutanea y el suministro transdermico de droga de lidocaina y/u otras drogas. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6980854B2 (es) |
EP (1) | EP1628709A1 (es) |
KR (1) | KR20060006095A (es) |
CN (1) | CN100581615C (es) |
AU (1) | AU2004243250A1 (es) |
CA (1) | CA2527201A1 (es) |
HK (1) | HK1095105A1 (es) |
MX (1) | MXPA05012823A (es) |
RU (1) | RU2005138794A (es) |
WO (1) | WO2004105868A1 (es) |
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US7496401B2 (en) * | 2001-04-06 | 2009-02-24 | Mattioli Engineering Ltd | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US7010343B2 (en) * | 2001-04-06 | 2006-03-07 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US7083580B2 (en) * | 2001-04-06 | 2006-08-01 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US7520875B2 (en) * | 2001-04-06 | 2009-04-21 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US6980854B2 (en) | 2001-04-06 | 2005-12-27 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery of lidocaine and/or other drugs |
US9283597B2 (en) * | 2002-12-02 | 2016-03-15 | Cfd Research Corporation | Miniaturized electrothermal flow induced infusion pump |
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CN103499519A (zh) * | 2013-10-10 | 2014-01-08 | 河南科技大学 | 一种复合物理场经皮给药实验装置 |
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KR100783195B1 (ko) | 2001-04-06 | 2007-12-06 | 마티올리 엔지니어링 엘티디. | 피부 흡수 향상 장치 |
US6743215B2 (en) | 2001-04-06 | 2004-06-01 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and cellulite reduction |
US7083580B2 (en) | 2001-04-06 | 2006-08-01 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US6748266B2 (en) | 2001-04-06 | 2004-06-08 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery |
US6980854B2 (en) | 2001-04-06 | 2005-12-27 | Mattioli Engineering Ltd. | Method and apparatus for skin absorption enhancement and transdermal drug delivery of lidocaine and/or other drugs |
EP2319577B1 (en) * | 2001-11-07 | 2017-03-15 | Syneron Medical Ltd. | Integrated transdermal drug delivery system |
-
2003
- 2003-05-30 US US10/448,468 patent/US6980854B2/en not_active Expired - Lifetime
-
2004
- 2004-05-27 CA CA002527201A patent/CA2527201A1/en not_active Abandoned
- 2004-05-27 KR KR1020057022885A patent/KR20060006095A/ko not_active Application Discontinuation
- 2004-05-27 AU AU2004243250A patent/AU2004243250A1/en not_active Abandoned
- 2004-05-27 WO PCT/IB2004/001760 patent/WO2004105868A1/en active Application Filing
- 2004-05-27 EP EP04735060A patent/EP1628709A1/en not_active Ceased
- 2004-05-27 MX MXPA05012823A patent/MXPA05012823A/es active IP Right Grant
- 2004-05-27 CN CN200480022368A patent/CN100581615C/zh not_active Expired - Lifetime
- 2004-05-27 RU RU2005138794/14A patent/RU2005138794A/ru not_active Application Discontinuation
-
2007
- 2007-03-06 HK HK07102480.6A patent/HK1095105A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2005138794A (ru) | 2006-04-10 |
WO2004105868A1 (en) | 2004-12-09 |
US6980854B2 (en) | 2005-12-27 |
KR20060006095A (ko) | 2006-01-18 |
CA2527201A1 (en) | 2004-12-09 |
US20040015190A1 (en) | 2004-01-22 |
CN100581615C (zh) | 2010-01-20 |
EP1628709A1 (en) | 2006-03-01 |
HK1095105A1 (en) | 2007-04-27 |
CN1832778A (zh) | 2006-09-13 |
AU2004243250A1 (en) | 2004-12-09 |
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