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MXPA04001856A - Indan-1-oles c2-sustituidos y sus derivados, metodo para su produccion y su uso como medicamentos. - Google Patents

Indan-1-oles c2-sustituidos y sus derivados, metodo para su produccion y su uso como medicamentos.

Info

Publication number
MXPA04001856A
MXPA04001856A MXPA04001856A MXPA04001856A MXPA04001856A MX PA04001856 A MXPA04001856 A MX PA04001856A MX PA04001856 A MXPA04001856 A MX PA04001856A MX PA04001856 A MXPA04001856 A MX PA04001856A MX PA04001856 A MXPA04001856 A MX PA04001856A
Authority
MX
Mexico
Prior art keywords
ols
production
derivatives
medicaments
substituted indane
Prior art date
Application number
MXPA04001856A
Other languages
English (en)
Inventor
Bickel Martin
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of MXPA04001856A publication Critical patent/MXPA04001856A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/17—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/20—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La invencion se relaciona a indan-1-oles C2-sustituidos y a sus sales fisiologicamente compatibles y derivados fisiologicamente funcionales. La invencion tambien se relaciona a compuestos de la formula (I), en donde los grupos se definen como por la descripcion, a sus sales fisiologicamente compatibles y a un metodo para la produccion de los compuestos. Los compuestos son adecuados para uso, por ejemplo, como anorexicos.
MXPA04001856A 2001-08-31 2002-08-17 Indan-1-oles c2-sustituidos y sus derivados, metodo para su produccion y su uso como medicamentos. MXPA04001856A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10142667A DE10142667B4 (de) 2001-08-31 2001-08-31 C2-substituierte Indan-1-ole und ihre Derivate und ihre Verwendung als Arzneimittel
PCT/EP2002/009206 WO2003020696A1 (de) 2001-08-31 2002-08-17 C2-substituierte indan-1-ole und ihre derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
MXPA04001856A true MXPA04001856A (es) 2004-06-15

Family

ID=7697237

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04001856A MXPA04001856A (es) 2001-08-31 2002-08-17 Indan-1-oles c2-sustituidos y sus derivados, metodo para su produccion y su uso como medicamentos.

Country Status (12)

Country Link
US (4) US6657086B2 (es)
EP (1) EP1425266B1 (es)
JP (1) JP4263999B2 (es)
AR (1) AR036676A1 (es)
AT (1) ATE429418T1 (es)
AU (1) AU2002333449B2 (es)
CA (1) CA2458527A1 (es)
DE (2) DE10142667B4 (es)
IL (1) IL160606A0 (es)
MX (1) MXPA04001856A (es)
PE (1) PE20030359A1 (es)
WO (1) WO2003020696A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10142666A1 (de) * 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142663B4 (de) 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme
EP1890690A4 (en) * 2005-06-02 2010-06-02 Jenrin Discovery MAO-B INHIBITORS FOR TREATING OBESITY

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3043824A (en) * 1959-09-28 1962-07-10 Exxon Research Engineering Co Hydroperoxide and sulfoxide compounds
US3016348A (en) * 1959-11-02 1962-01-09 Universal Oil Prod Co Manufacture and use of sulfided hydrocarbon purification catalyst
US3642785A (en) * 1969-08-11 1972-02-15 Merck & Co Inc Indenyl-3-aliphatic amines
FR2201882B1 (es) * 1972-07-20 1975-10-31 Logeais Labor Jacques
GB1465794A (en) * 1974-05-17 1977-03-02 Wyeth John & Brother Ltd Thiourea derivatives
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
EP0009554B1 (de) 1978-07-27 1983-04-27 Schering Aktiengesellschaft Indanyl-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
MX13484A (es) 1987-10-19 1993-05-01 Pfizer Procedimiento para la obtencion de tetralinas, cromanos y compuestos relacionados, sustituidos
WO1997020805A1 (en) 1995-12-06 1997-06-12 Venantius Limited Indane dimer compounds with smooth muscle relaxing and/or mast cell stabilising and/or antiinflammatory activity
AU727775B2 (en) 1996-01-17 2000-12-21 Novo Nordisk A/S Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
WO1997041097A2 (en) 1996-12-31 1997-11-06 Dr. Reddy's Research Foundation Novel heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
DE19705402B4 (de) 1996-07-17 2007-04-26 Robert Bosch Gmbh Gassensor
DE69737479T4 (de) 1996-08-30 2010-05-06 Novo Nordisk A/S Glp-1 derivate
CA2294830A1 (en) 1997-07-16 1999-01-28 John Bondo Hansen Fused 1,2,4-thiadiazine derivatives, their preparation and use
FR2769312B1 (fr) * 1997-10-03 1999-12-03 Adir Nouveaux composes de l'indanol, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2782515B1 (fr) * 1998-08-21 2000-09-22 Adir NOUVEAUX DERIVES DE L'INDANE-1-Ol, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
EP1078632A1 (en) 1999-08-16 2001-02-28 Sanofi-Synthelabo Use of monoamine oxydase inhibitors for the manufacture of drugs intended for the treatment of obesity

Also Published As

Publication number Publication date
AU2002333449B2 (en) 2007-09-06
DE50213487D1 (de) 2009-06-04
EP1425266B1 (de) 2009-04-22
DE10142667B4 (de) 2004-06-09
WO2003020696A1 (de) 2003-03-13
US7045649B2 (en) 2006-05-16
CA2458527A1 (en) 2003-03-13
EP1425266A1 (de) 2004-06-09
ATE429418T1 (de) 2009-05-15
AR036676A1 (es) 2004-09-29
US20050113595A1 (en) 2005-05-26
IL160606A0 (en) 2004-07-25
US20050101798A1 (en) 2005-05-12
US6657086B2 (en) 2003-12-02
PE20030359A1 (es) 2003-05-20
US20040068016A1 (en) 2004-04-08
JP4263999B2 (ja) 2009-05-13
US20030114681A1 (en) 2003-06-19
JP2005525297A (ja) 2005-08-25
US7015208B2 (en) 2006-03-21
DE10142667A1 (de) 2003-03-27

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Legal Events

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