MXPA01013406A - Vla-4 inhibitor compounds. - Google Patents
Vla-4 inhibitor compounds.Info
- Publication number
- MXPA01013406A MXPA01013406A MXPA01013406A MXPA01013406A MXPA01013406A MX PA01013406 A MXPA01013406 A MX PA01013406A MX PA01013406 A MXPA01013406 A MX PA01013406A MX PA01013406 A MXPA01013406 A MX PA01013406A MX PA01013406 A MXPA01013406 A MX PA01013406A
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- Prior art keywords
- vla
- inhibitor compounds
- inhibitor
- compounds
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14160299P | 1999-06-30 | 1999-06-30 | |
US14169299P | 1999-06-30 | 1999-06-30 | |
US14160199P | 1999-06-30 | 1999-06-30 | |
PCT/US2000/018079 WO2001000206A1 (en) | 1999-06-30 | 2000-06-30 | Vla-4 inhibitor compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA01013406A true MXPA01013406A (en) | 2003-09-04 |
Family
ID=27385682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA01013406A MXPA01013406A (en) | 1999-06-30 | 2000-06-30 | Vla-4 inhibitor compounds. |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1189612A4 (en) |
JP (1) | JP2003503350A (en) |
CN (1) | CN1391473A (en) |
AR (1) | AR035011A1 (en) |
AU (1) | AU781438B2 (en) |
BR (1) | BR0012068A (en) |
CA (1) | CA2369308A1 (en) |
HK (1) | HK1043318A1 (en) |
IL (1) | IL146288A0 (en) |
MX (1) | MXPA01013406A (en) |
NO (1) | NO324892B1 (en) |
TW (1) | TWI283240B (en) |
WO (1) | WO2001000206A1 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
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BR0107624A (en) | 2000-01-17 | 2002-11-12 | Bayer Ag | Substituted aryl ketones |
DE10006453A1 (en) * | 2000-02-14 | 2001-08-16 | Bayer Ag | New piperidylcarboxylic acid derivatives, are integrin antagonists useful for treating inflammatory, autoimmune or immunological diseases, e.g. atherosclerosis, asthma, diabetes, rheumatoid arthritis or transplant rejection |
US6638950B2 (en) | 2000-06-21 | 2003-10-28 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
TWI312779B (en) | 2000-12-28 | 2009-08-01 | Daiichi Seiyaku Co | |
EP1862457B1 (en) | 2001-06-27 | 2010-01-20 | SmithKline Beecham Corporation | Fluoropyrrolidines as dipeptidyl peptidase inhibitors |
GB0123765D0 (en) * | 2001-10-03 | 2001-11-21 | Bayer Ag | Para-amino benzoic acids |
DE60325959D1 (en) * | 2002-05-09 | 2009-03-12 | Baker Medical Res Inst Prahran | Amino Acid Analogs |
PL215132B1 (en) | 2002-06-27 | 2013-10-31 | Novo Nordisk As | Aryl carbonyl derivatives as therapeutic agents |
RU2340605C2 (en) | 2002-06-27 | 2008-12-10 | Ново Нордиск А/С | Arylcarbonyl derivatives as therapeutic agents |
AU2003241836A1 (en) | 2002-10-03 | 2004-04-23 | Ono Pharmaceutical Co., Ltd. | Lpa receptor antagonists |
GB0225944D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
WO2004099136A1 (en) | 2003-05-09 | 2004-11-18 | Daiichi Pharmaceutical Co., Ltd. | Process for producing pyrrolidine derivative |
WO2005009992A1 (en) | 2003-07-24 | 2005-02-03 | Daiichi Pharmaceutical Co., Ltd. | Cyclohexanecarboxylic acid compound |
TW200526631A (en) * | 2003-10-07 | 2005-08-16 | Renovis Inc | Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same |
BRPI0506662B8 (en) | 2004-01-06 | 2021-05-25 | Novo Nordisk As | glucokinase activating compounds |
JP2005350417A (en) * | 2004-06-11 | 2005-12-22 | Dai Ichi Seiyaku Co Ltd | Method for producing pyrrolidine derivative using reductive etherification method |
CA2576647C (en) * | 2004-08-16 | 2011-12-13 | Merck & Co., Inc. | Vla-4 antagonists |
WO2007069635A1 (en) | 2005-12-13 | 2007-06-21 | Daiichi Sankyo Company, Limited | Vla-4 inhibitory drug |
WO2009050201A2 (en) | 2007-10-16 | 2009-04-23 | Novartis Ag | 4-phenyl-5-oxo-imidazole derivatives, pharmaceutical compositions and uses therof |
MX2010010502A (en) * | 2008-03-26 | 2010-10-26 | Novartis Ag | Hydroxamate-based inhibitors of deacetylases b. |
PL2513085T3 (en) | 2009-11-18 | 2017-09-29 | Suven Life Sciences Limited | Bicyclic compounds as alpha4beta2 nicotinic acetylcholine receptor ligands |
WO2012137982A2 (en) * | 2011-04-05 | 2012-10-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
KR20210020866A (en) | 2018-06-12 | 2021-02-24 | 브이티브이 테라퓨틱스 엘엘씨 | The therapeutic use of glucokinase activators in combination with insulin or insulin analogues |
CN112996786B (en) | 2018-10-30 | 2024-08-20 | 吉利德科学公司 | Compounds for inhibiting alpha 4 beta 7 integrin |
CA3115830C (en) | 2018-10-30 | 2023-09-12 | Gilead Sciences, Inc. | Compounds for inhibition of .alpha.4.beta.7 integrin |
KR20240015737A (en) | 2018-10-30 | 2024-02-05 | 길리애드 사이언시즈, 인코포레이티드 | Quinoline derivatives as alpha4beta7 integrin inhibitors |
JP7214882B2 (en) | 2018-10-30 | 2023-01-30 | ギリアード サイエンシーズ, インコーポレイテッド | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
ES2980245T3 (en) | 2019-02-26 | 2024-09-30 | Bayer Ag | Condensed bicyclic heterocycle derivatives as pesticide |
US11578069B2 (en) | 2019-08-14 | 2023-02-14 | Gilead Sciences, Inc. | Compounds for inhibition of α4 β7 integrin |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
US6248713B1 (en) * | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | Heterocyclic amide compounds as cell adhesion inhibitors |
WO1999020272A1 (en) * | 1997-10-21 | 1999-04-29 | Merck & Co., Inc. | Azapeptide acids as cell adhesion inhibitors |
SK5462000A3 (en) * | 1997-10-31 | 2001-02-12 | Aventis Pharma Ltd | Substituted anilides |
AU3716499A (en) * | 1998-04-21 | 1999-11-08 | Aventis Pharma Limited | Substituted diamines and their use as cell adhesion inhibitors |
NZ508033A (en) * | 1998-06-30 | 2002-12-20 | Pfizer Prod Inc | Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases |
-
2000
- 2000-06-30 WO PCT/US2000/018079 patent/WO2001000206A1/en active IP Right Grant
- 2000-06-30 CN CN00809510A patent/CN1391473A/en active Pending
- 2000-06-30 MX MXPA01013406A patent/MXPA01013406A/en active IP Right Grant
- 2000-06-30 AU AU59031/00A patent/AU781438B2/en not_active Ceased
- 2000-06-30 EP EP00945035A patent/EP1189612A4/en not_active Withdrawn
- 2000-06-30 BR BR0012068-5A patent/BR0012068A/en not_active Application Discontinuation
- 2000-06-30 TW TW089112968A patent/TWI283240B/en not_active IP Right Cessation
- 2000-06-30 AR ARP000103363A patent/AR035011A1/en unknown
- 2000-06-30 IL IL14628800A patent/IL146288A0/en not_active IP Right Cessation
- 2000-06-30 CA CA002369308A patent/CA2369308A1/en not_active Abandoned
- 2000-06-30 JP JP2001505915A patent/JP2003503350A/en active Pending
-
2001
- 2001-12-21 NO NO20016319A patent/NO324892B1/en unknown
-
2002
- 2002-07-09 HK HK02105102.2A patent/HK1043318A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
AR035011A1 (en) | 2004-04-14 |
TWI283240B (en) | 2007-07-01 |
NO324892B1 (en) | 2007-12-27 |
EP1189612A4 (en) | 2005-02-16 |
EP1189612A1 (en) | 2002-03-27 |
NO20016319D0 (en) | 2001-12-21 |
IL146288A0 (en) | 2002-07-25 |
NO20016319L (en) | 2002-02-28 |
HK1043318A1 (en) | 2002-09-13 |
JP2003503350A (en) | 2003-01-28 |
AU5903100A (en) | 2001-01-31 |
AU781438B2 (en) | 2005-05-26 |
WO2001000206A1 (en) | 2001-01-04 |
CN1391473A (en) | 2003-01-15 |
BR0012068A (en) | 2002-05-14 |
CA2369308A1 (en) | 2001-01-04 |
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