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MX9604762A - Nuevas sulfonamidas y procedimiento para su preparacion. - Google Patents

Nuevas sulfonamidas y procedimiento para su preparacion.

Info

Publication number
MX9604762A
MX9604762A MX9604762A MX9604762A MX9604762A MX 9604762 A MX9604762 A MX 9604762A MX 9604762 A MX9604762 A MX 9604762A MX 9604762 A MX9604762 A MX 9604762A MX 9604762 A MX9604762 A MX 9604762A
Authority
MX
Mexico
Prior art keywords
preparation
novel sulfonamides
sulfonamides
novel
compounds
Prior art date
Application number
MX9604762A
Other languages
English (en)
Inventor
Volker Breu
Jean-Marie Cassal
Georges Hirth
Marcel Muller
Henri Ramuz
Kaspar Burri
Martine Clozel
Bernd-Michael Loffler
Werner Neidhart
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX9604762A publication Critical patent/MX9604762A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69—Benzenesulfonamido-pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compuestos de formula general (I) en donde R1-R6, Ra, Rb, X, Y, Z, m y n tienen el significado dado en la descripcion, pueden usarse como medicamentos en especial para el tratamiento de trastornos asociados con las actividades de la endotelina.
MX9604762A 1995-10-12 1996-10-11 Nuevas sulfonamidas y procedimiento para su preparacion. MX9604762A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH289395 1995-10-12

Publications (1)

Publication Number Publication Date
MX9604762A true MX9604762A (es) 1997-04-30

Family

ID=4243971

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9604762A MX9604762A (es) 1995-10-12 1996-10-11 Nuevas sulfonamidas y procedimiento para su preparacion.

Country Status (28)

Country Link
US (1) US5856484A (es)
EP (1) EP0768304B1 (es)
JP (1) JP2723496B2 (es)
CN (1) CN1115339C (es)
AR (1) AR004215A1 (es)
AT (1) ATE217867T1 (es)
AU (1) AU706748B2 (es)
BR (1) BR9605046B1 (es)
CA (1) CA2187130C (es)
CO (1) CO4770959A1 (es)
CZ (1) CZ260596A3 (es)
DE (1) DE59609225D1 (es)
DK (1) DK0768304T3 (es)
ES (1) ES2175006T3 (es)
HU (1) HUP9602748A3 (es)
IL (1) IL119371A (es)
MA (1) MA23980A1 (es)
MX (1) MX9604762A (es)
NO (1) NO308000B1 (es)
NZ (1) NZ299519A (es)
PE (1) PE17098A1 (es)
PL (1) PL316486A1 (es)
PT (1) PT768304E (es)
SG (1) SG46753A1 (es)
TR (1) TR199600778A2 (es)
TW (1) TW438779B (es)
UY (1) UY24346A1 (es)
ZA (1) ZA968451B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ260596A3 (en) * 1995-10-12 1997-12-17 Hoffmann La Roche Sulfonamide derivative, process of its preparation and pharmaceutical composition containing thereof
JP4058507B2 (ja) 1997-07-10 2008-03-12 国立大学法人 東京医科歯科大学 ４，５−ジヒドロ−［１Ｈ］−ベンズ［ｇ］インダゾール−３−カルボン酸誘導体
US6191170B1 (en) 1998-01-13 2001-02-20 Tularik Inc. Benzenesulfonamides and benzamides as therapeutic agents
US6136971A (en) * 1998-07-17 2000-10-24 Roche Colorado Corporation Preparation of sulfonamides
CA2315614C (en) * 1999-07-29 2004-11-02 Pfizer Inc. Pyrazoles
AU3536701A (en) * 1999-12-22 2001-07-03 Actelion Pharmaceuticals Ltd Butyne diol derivatives
US6720322B2 (en) 1999-12-22 2004-04-13 Actelion Pharamceuticals Ltd. Butyne diol derivatives
AU2001265871A1 (en) * 2000-04-25 2001-11-07 Actelion Pharmaceuticals Ltd Substituted sulfonylaminopyrimidines
US6387915B2 (en) 2000-05-31 2002-05-14 Pfizer Inc. Isoxazole-sulfonamide endothelin antagonists
US6670362B2 (en) 2000-09-20 2003-12-30 Pfizer Inc. Pyridazine endothelin antagonists
US8463964B2 (en) * 2009-05-29 2013-06-11 Invensys Systems, Inc. Methods and apparatus for control configuration with enhanced change-tracking

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW270116B (es) * 1991-04-25 1996-02-11 Hoffmann La Roche
RU2086544C1 (ru) * 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
TW287160B (es) * 1992-12-10 1996-10-01 Hoffmann La Roche
TW394761B (en) * 1993-06-28 2000-06-21 Hoffmann La Roche Novel Sulfonylamino Pyrimidines
IL111959A (en) * 1993-12-17 2000-07-16 Tanabe Seiyaku Co N-(polysubstituted pyrimidin-4-yl) benzenesulfonamide derivatives their preparation and pharmaceutical compositions containing them
CZ260596A3 (en) * 1995-10-12 1997-12-17 Hoffmann La Roche Sulfonamide derivative, process of its preparation and pharmaceutical composition containing thereof

Also Published As

Publication number Publication date
TR199600778A2 (tr) 1997-04-22
BR9605046A (pt) 1998-06-30
IL119371A (en) 2001-04-30
CZ260596A3 (en) 1997-12-17
NO308000B1 (no) 2000-07-03
BR9605046B1 (pt) 2010-08-10
MA23980A1 (fr) 1997-07-01
JP2723496B2 (ja) 1998-03-09
DK0768304T3 (da) 2002-09-09
ATE217867T1 (de) 2002-06-15
HU9602748D0 (en) 1996-11-28
EP0768304A1 (de) 1997-04-16
PL316486A1 (en) 1997-04-14
PT768304E (pt) 2002-10-31
NO964334D0 (no) 1996-10-11
CA2187130A1 (en) 1997-04-13
SG46753A1 (en) 1998-02-20
JPH09110840A (ja) 1997-04-28
CA2187130C (en) 2006-10-03
NO964334L (no) 1997-04-14
AU6817296A (en) 1997-04-17
IL119371A0 (en) 1997-01-10
ZA968451B (en) 1997-04-14
PE17098A1 (es) 1998-04-15
CO4770959A1 (es) 1999-04-30
CN1151400A (zh) 1997-06-11
US5856484A (en) 1999-01-05
CN1115339C (zh) 2003-07-23
NZ299519A (en) 1998-02-26
AU706748B2 (en) 1999-06-24
EP0768304B1 (de) 2002-05-22
ES2175006T3 (es) 2002-11-16
HUP9602748A2 (en) 1997-05-28
HUP9602748A3 (en) 1998-04-28
TW438779B (en) 2001-06-07
DE59609225D1 (de) 2002-06-27
UY24346A1 (es) 2001-03-16
AR004215A1 (es) 1998-11-04

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees