[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

MX9306588A - Compuesto de acilo antirretrovirales. - Google Patents

Compuesto de acilo antirretrovirales.

Info

Publication number
MX9306588A
MX9306588A MX9306588A MX9306588A MX9306588A MX 9306588 A MX9306588 A MX 9306588A MX 9306588 A MX9306588 A MX 9306588A MX 9306588 A MX9306588 A MX 9306588A MX 9306588 A MX9306588 A MX 9306588A
Authority
MX
Mexico
Prior art keywords
antirretroviral
acyl compound
acyl
compound
salts
Prior art date
Application number
MX9306588A
Other languages
English (en)
Inventor
Guido Bold
Alexander Fassler
Marc Lang
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of MX9306588A publication Critical patent/MX9306588A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)

Abstract

La presente invención se refiere a compuestos de la fórmula (I) en donde R1 es acilo y a sales de los mismos, los cuales exhiben actividad antirretroviral, especialmente contra el SIDA.
MX9306588A 1992-10-23 1993-10-22 Compuesto de acilo antirretrovirales. MX9306588A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH331292 1992-10-23

Publications (1)

Publication Number Publication Date
MX9306588A true MX9306588A (es) 1994-05-31

Family

ID=4253267

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9306588A MX9306588A (es) 1992-10-23 1993-10-22 Compuesto de acilo antirretrovirales.

Country Status (19)

Country Link
EP (1) EP0594540B1 (es)
JP (1) JPH06228132A (es)
KR (1) KR940009177A (es)
CN (1) CN1089606A (es)
AT (1) ATE164592T1 (es)
AU (1) AU670121B2 (es)
CA (1) CA2108934A1 (es)
CZ (1) CZ223893A3 (es)
DE (1) DE59308336D1 (es)
FI (1) FI934634A (es)
HU (1) HU214330B (es)
IL (1) IL107356A (es)
MX (1) MX9306588A (es)
NO (1) NO933816L (es)
NZ (1) NZ250017A (es)
PL (1) PL173529B1 (es)
SK (1) SK115193A3 (es)
TW (1) TW372972B (es)
ZA (1) ZA937859B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040122000A1 (en) 1981-01-07 2004-06-24 Vertex Pharmaceuticals Incorporated. Inhibitors of aspartyl protease
US6878728B1 (en) 1999-06-11 2005-04-12 Vertex Pharmaceutical Incorporated Inhibitors of aspartyl protease
US5888992A (en) 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
WO1993018006A1 (en) 1992-03-11 1993-09-16 Narhex Limited Amine derivatives of oxo- and hydroxy-substitued hydrocarbons
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
DE69333270T2 (de) 1992-03-11 2004-08-05 Narhex Ltd. Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
DE19500120A1 (de) 1995-01-04 1996-07-11 Bayer Ag Neue acylierte Pseudopeptide mit trifluormethyl-subsstituiertem 2-Azabicyclooctan
DE19500122A1 (de) * 1995-01-04 1996-07-11 Bayer Ag Neue Pseudopeptide mit trifluormethyl-substituierten 2-Azabicyclooctan
US6008228A (en) * 1995-06-06 1999-12-28 Hoffman-La Roche Inc. Pharmaceutical compositions containing proteinase inhibitors
US6436989B1 (en) 1997-12-24 2002-08-20 Vertex Pharmaceuticals, Incorporated Prodrugs of aspartyl protease inhibitors
NZ508855A (en) 1998-06-19 2003-10-31 Vertex Pharma Sulfonamide inhibitors of HIV aspartyl protease
US6319946B1 (en) 1999-02-12 2001-11-20 Vertex Pharmaceuticals Incorporated Inhibitors of aspartyl protease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668685A (en) * 1984-07-05 1987-05-26 E.I. Du Pont De Nemours And Company Substituted benzoate ester prodrug derivatives of 3-hydroxymorphinans, which are analgesics or narcotic antagonists
US5024968A (en) * 1988-07-08 1991-06-18 Engelsberg Audrey C Removal of surface contaminants by irradiation from a high-energy source
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
GB8927915D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Novel alcohols

Also Published As

Publication number Publication date
CZ223893A3 (en) 1994-05-18
TW372972B (en) 1999-11-01
DE59308336D1 (de) 1998-05-07
HU9303011D0 (en) 1994-01-28
ATE164592T1 (de) 1998-04-15
FI934634A (fi) 1994-04-24
ZA937859B (en) 1994-04-25
HUT65876A (en) 1994-07-28
CA2108934A1 (en) 1994-04-24
HU214330B (hu) 1998-03-02
AU4907293A (en) 1994-05-05
IL107356A (en) 1998-01-04
FI934634A0 (fi) 1993-10-20
KR940009177A (ko) 1994-05-20
NO933816D0 (no) 1993-10-22
JPH06228132A (ja) 1994-08-16
IL107356A0 (en) 1994-01-25
EP0594540A1 (de) 1994-04-27
AU670121B2 (en) 1996-07-04
NO933816L (no) 1994-04-25
EP0594540B1 (de) 1998-04-01
PL173529B1 (pl) 1998-03-31
NZ250017A (en) 1996-04-26
CN1089606A (zh) 1994-07-20
SK115193A3 (en) 1994-11-09

Similar Documents

Publication Publication Date Title
ATE196761T1 (de) Inhibitoren retroviraler proteasen
DE69615682D1 (de) N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h-benzo[b][1,5]-diazepin-3-yl)-acetamide
FI914928A (fi) Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
ES538757A0 (es) Procedimiento para la preparacion de 11b-aril-estradienos
MX9306588A (es) Compuesto de acilo antirretrovirales.
ES2052463T1 (es) Antihipercolesterolemicos.
MX9201760A (es) Quinoxalinas, procedimiento para su preparacion y su empleo.
SE9004060D0 (sv) Bensazepin- och bensotiazepin-derivat
ES2193241T3 (es) Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
DE3772015D1 (de) Chinolinverbindung.
ES2136887T3 (es) Derivados antifungicos de sordaridina.
SE9100920D0 (sv) New active compounds
FI863836A (fi) Kinolinderivat.
ES2194102T3 (es) Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
ES2093037T3 (es) Derivados de beta-lactama y su preparacion.
DK0696278T3 (da) Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler
DE69825977D1 (de) Antivirale mittel
FI963168A (fi) Enkefalinaasin inhibiittoreina käyttökelpoisia uusia indaani-2-merkaptoasetyyliamiddisulfidijohdannaisia
FI892681A0 (fi) Nya jodade icke-joniska trijodbenzenfoereningar och dessa innehaollande kontrastmedel.
EA199900888A1 (ru) Противоревматические средства
DK0623620T3 (da) 5-HT3-pyrrolopyrazinderivater
DK0623131T3 (da) Alkylderivater af trazodon med CNS-aktivitet
RU93048166A (ru) Антиретровирусные ацилсоединения
TH13552EX (th) อนุพันธุ์ต่าง ๆ ของเบนโซฟิโนน
SE9000857D0 (sv) Novel use of theraeutically active compound