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MX9304563A - DEXIBUPROFEN / ANTI-ACID / SIMETICONE COMBINATIONS - Google Patents

DEXIBUPROFEN / ANTI-ACID / SIMETICONE COMBINATIONS

Info

Publication number
MX9304563A
MX9304563A MX9304563A MX9304563A MX9304563A MX 9304563 A MX9304563 A MX 9304563A MX 9304563 A MX9304563 A MX 9304563A MX 9304563 A MX9304563 A MX 9304563A MX 9304563 A MX9304563 A MX 9304563A
Authority
MX
Mexico
Prior art keywords
heartburn
ibuprofen
acid
simeticone
dexibuprofen
Prior art date
Application number
MX9304563A
Other languages
Spanish (es)
Inventor
William Slivka
Robert T Sims
Thomas N Gates
Original Assignee
Merck & Co Inc
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc, Mcneil Ppc Inc filed Critical Merck & Co Inc
Publication of MX9304563A publication Critical patent/MX9304563A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se refiere a composiciones farmacéuticas para utilizarse en el tratamiento de dolor e inflamación, y en el alivio de indigestión, acidez estomacal, agruras, y otros desórdenes gastrointestinales en mamíferos, incluyendo seres humanos, mediante la administración de composiciones que incluyen : (i) una cantidad analgésicamente y antiinflamatoriamente efectiva de una sal de (S)-ibuprofén substancialmente libre de (R)-ibuprofén, donde la sal se selecciona a partir de (S)-ibuprofén-(S)-lisina y (S)-ibupofrén-(R)-lisina; y (ii) una cantidad efectiva en el tratamiento de indigestión ácida, acidez estomacal, agruras y otros desórdenes gastrointestinales de un antiácido; y (iii) simeticona.The present invention relates to pharmaceutical compositions for use in the treatment of pain and inflammation, and in the relief of indigestion, heartburn, heartburn, and other gastrointestinal disorders in mammals, including humans, by administration of compositions including: ( i) an analgesically and anti-inflammatory effective amount of a (S) -ibuprofen salt substantially free of (R) -ibuprofen, where the salt is selected from (S) -ibuprofen- (S) -lysine and (S) - ibupofren- (R) -lysine; and (ii) an effective amount in the treatment of acid indigestion, heartburn, heartburn and other gastrointestinal disorders of an antacid; and (iii) simethicone.

MX9304563A 1992-07-29 1993-07-28 DEXIBUPROFEN / ANTI-ACID / SIMETICONE COMBINATIONS MX9304563A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92188092A 1992-07-29 1992-07-29

Publications (1)

Publication Number Publication Date
MX9304563A true MX9304563A (en) 1994-02-28

Family

ID=25446110

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304563A MX9304563A (en) 1992-07-29 1993-07-28 DEXIBUPROFEN / ANTI-ACID / SIMETICONE COMBINATIONS

Country Status (3)

Country Link
AU (1) AU4682193A (en)
MX (1) MX9304563A (en)
WO (1) WO1994003209A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012460A1 (en) * 1992-12-02 1994-06-09 The Boots Company Plc Process for preparing substantially pure enantiomers of phenylpropionic acids
CZ300696A3 (en) * 1994-03-18 1997-09-17 Alfred Schmidt USE OF DEMETICON FOR PREPARING A PHARMACEUTICAL COMPOSITION FOR LOCAL AND ANTIBACTERIAL THERAPY AND/OR PREVENTION AND THERAPY OF SYNDROMES AND INFECTIOUS DISEASES CONNECTED WITH HELIOBACTER PYLORI (Hp)
DE4409357C2 (en) * 1994-03-18 1996-10-17 Upmeyer Hans Juergen Use of Dimeticon to eradicate Heliobacter pylori
US5498426A (en) * 1994-10-03 1996-03-12 The Procter & Gamble Company Liquid antacid compositions
DE19502789A1 (en) * 1995-01-28 1996-08-01 Dirk Krischenowski Medicament contg. analgesic, antacid, and/or vitamin etc.
US6028062A (en) * 1995-03-15 2000-02-22 Upmeyer; Hans-Juergen Use of dimeticone for the local antibacterial therapy and/or the prevention and therapy of helicobacter pylori (Hp) associated syndromes and infectious diseases
IT1317826B1 (en) * 2000-02-11 2003-07-15 Dompe Spa AMIDES, USEFUL IN THE INHIBITION OF THE CHEMOTAXIS OF NEUTROPHILES INDUCED BY IL-8.
ITMI20010395A1 (en) 2001-02-27 2002-08-27 Dompe Spa OMEGA-AMINO ALKYLAMIDS OF R-2-ARYL-PROPIONIC ACIDS AS INHIBITORS OF CHEMOTAXIS OF POLYMORPHONUCLEATED AND MONONUCLEATE CELLS
KR20050005883A (en) * 2003-07-07 2005-01-15 안국약품 주식회사 Antipyretic Medicine Containing Dexibuprofen As An Effective Component

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
KR920002148A (en) * 1990-07-03 1992-02-28 안드레아 엘. 콜비 Pharmaceutical compositions for alleviating gastrointestinal symptoms caused by nonsteroidal anti-inflammatory drugs and methods for alleviating the same

Also Published As

Publication number Publication date
WO1994003209A1 (en) 1994-02-17
AU4682193A (en) 1994-03-03

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