MX9201416A - ANTITHROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. - Google Patents

ANTITHROMBOTIC PEPTIDES AND PSEUDOPEPTIDES.

Info

Publication number: MX9201416A
Authority: MX; Mexico
Prior art keywords: pseudopeptides; antithrombotic peptides; antithrombotic; peptides
Prior art date: 1991-03-28

Application number

MX9201416A

Other languages

Spanish (es)

Inventor

Scott I Klein

Bruce F Molino

Mark Czekaj

Charles J Gardner

Michael R Becker

Jeffrey M Dener

Original Assignee

Rhone Poulenc Rorer Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-28

Filing date

1992-03-27

Publication date

1992-10-01

1992-03-27 Application filed by Rhone Poulenc Rorer Int filed Critical Rhone Poulenc Rorer Int

1992-10-01 Publication of MX9201416A publication Critical patent/MX9201416A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Crystallography & Structural Chemistry (AREA)
Hematology (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

MX9201416A 1991-03-28 1992-03-27 ANTITHROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. MX9201416A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US67700691A	1991-03-28	1991-03-28

Publications (1)

Publication Number	Publication Date
MX9201416A true MX9201416A (en)	1992-10-01

Family

ID=24716920

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX9201416A MX9201416A (en)	1991-03-28	1992-03-27	ANTITHROMBOTIC PEPTIDES AND PSEUDOPEPTIDES.

Country Status (6)

Country	Link
EP (1)	EP0577775A4 (en)
JP (1)	JPH06506699A (en)
AU (1)	AU673497B2 (en)
CA (1)	CA2107088A1 (en)
MX (1)	MX9201416A (en)
WO (1)	WO1992017196A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6521594B1 (en)	1990-04-06	2003-02-18	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US6017877A (en) *	1990-04-06	2000-01-25	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US5780303A (en) *	1990-04-06	1998-07-14	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
US5672585A (en) *	1990-04-06	1997-09-30	La Jolla Cancer Research Foundation	Method and composition for treating thrombosis
WO1994014775A1 (en) *	1992-12-29	1994-07-07	Smithkline Beecham Corporation	Platelet aggregation inhibiting compounds
US5652242A (en) *	1993-03-29	1997-07-29	Zeneca Limited	Heterocyclic derivatives
EP0691959B1 (en) *	1993-03-29	1998-07-22	Zeneca Limited	Heterocyclic derivatives as platelet aggregation inhibitors
US5750754A (en) *	1993-03-29	1998-05-12	Zeneca Limited	Heterocyclic compounds
CA2155307A1 (en) *	1993-03-29	1994-10-13	Michael Garth Wayne	Heterocyclic compounds as platelet aggregation inhibitors
US5753659A (en) *	1993-03-29	1998-05-19	Zeneca Limited	Heterocyclic compouds
US5516889A (en) *	1993-06-21	1996-05-14	University Technologies International, Inc.	Synthetic thrombin receptor peptides
US5463011A (en) *	1993-06-28	1995-10-31	Zeneca Limited	Acid derivatives
GB9313268D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Chemical compounds
GB9313285D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Acid derivatives
US5780590A (en) *	1993-10-15	1998-07-14	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
US5639765A (en) *	1995-01-17	1997-06-17	G. D. Searle & Co.	Guanidinoalkyl glycine β-amino acids useful for inhibiting bone loss
US5602155A (en) *	1995-01-17	1997-02-11	G. D. Searle & Co.	Platelet aggregation inhibitors
US5681820A (en) *	1995-05-16	1997-10-28	G. D. Searle & Co.	Guanidinoalkyl glycine β-amino acids useful for inhibiting tumor metastasis
CA3117599A1 (en) *	2018-10-29	2020-05-07	Huahai Us Inc.	Novel dipeptide compounds and uses thereof
AU2022238571A1 (en)	2021-03-18	2023-09-14	Seagen Inc.	Selective drug release from internalized conjugates of biologically active compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0136879A3 (en) *	1983-09-30	1987-01-07	Yamanouchi Pharmaceutical Co., Ltd.	Fatty acid derivatives and processes of producing them
US5037808A (en) *	1988-07-20	1991-08-06	Monsanto Co.	Indolyl platelet-aggregation inhibitors
US5053393A (en) *	1988-07-20	1991-10-01	Monsanto Company	Novel platelet-aggregation inhibitor
US4992463A (en) *	1988-07-20	1991-02-12	Monsanto Company	Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation
US4879313A (en) *	1988-07-20	1989-11-07	Mosanto Company	Novel platelet-aggregation inhibitors
HU201964B (en) *	1989-01-13	1991-01-28	Richter Gedeon Vegyeszet	Process for producing peptides inhibiting maturation of t-lymphocytes and activity of macrophages, as well as pharmaceutical compositions comprising same
US4952562A (en) *	1989-09-29	1990-08-28	Rorer Pharmaceutical Corporation	Anti-thrombotic peptides and pseudopeptides
AU646411B2 (en) *	1989-09-29	1994-02-24	Rhone-Poulenc Rorer International (Holdings) Inc.	Anti-thrombotic peptides and pseudopeptides

1992
- 1992-03-27 MX MX9201416A patent/MX9201416A/en unknown
- 1992-03-30 JP JP4511653A patent/JPH06506699A/en active Pending
- 1992-03-30 CA CA002107088A patent/CA2107088A1/en not_active Abandoned
- 1992-03-30 WO PCT/US1992/002637 patent/WO1992017196A1/en not_active Application Discontinuation
- 1992-03-30 EP EP92912095A patent/EP0577775A4/en not_active Withdrawn
- 1992-03-30 AU AU20143/92A patent/AU673497B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU673497B2 (en)	1996-11-14
CA2107088A1 (en)	1992-09-29
JPH06506699A (en)	1994-07-28
WO1992017196A1 (en)	1992-10-15
EP0577775A1 (en)	1994-01-12
AU2014392A (en)	1992-11-02
EP0577775A4 (en)	1995-01-11

Publication	Publication Date	Title
DE69129395D1 (en)	1998-06-18	Antimicrobial peptides
NO942066L (en)	1994-06-03	peptide
MX9201416A (en)	1992-10-01	ANTITHROMBOTIC PEPTIDES AND PSEUDOPEPTIDES.
BR9307895A (en)	1996-09-10	Chair
FI921125A0 (en)	1992-03-16	Ciclosporin.
BR9403045A (en)	1995-05-02	Molded zipper.
LV10962A (en)	1995-12-20	New peptide
EP0445801A3 (en)	1992-07-01	Peptide and its use
FI940109A (en)	1994-10-11	peptides
TR199500915A2 (en)	1996-06-21	Peptides.
NO990836D0 (en)	1999-02-22	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
DE69427363D1 (en)	2001-07-05	Platelet-inhibiting peptides
GB9016810D0 (en)	1990-09-12	Peptides
KR960010685A (en)	1996-04-20	Peptides and their uses
ITGE940084A0 (en)	1994-06-22	CHAIR
NO932237D0 (en)	1993-06-17	LINEAR PEPTIDES
EP0579611A4 (en)	1995-04-19	Peptides.
DE69112932D1 (en)	1995-10-19	Compressor.
NO903833D0 (en)	1990-09-03	Hirudin peptides.
FI904766A (en)	1992-03-28	FOERFARANDE FOER DETEKTERING AV PROTEIN.
DE68914057D1 (en)	1994-04-28	Peptides.
AU5939994A (en)	1994-06-09	Linear peptides and uses thereof
KR940020828U (en)	1994-09-17	Joiner's Packing in Floring
IE902004L (en)	1990-12-06	Peptides.
DK104493D0 (en)	1993-09-17	HIS UNKNOWN PEPTIDES