MX4841E - Procedimiento para la preparacion de 2-bromo-6-fluor-n-2-imidazolidiniliden-benzamina y sus sales por adicion de acido - Google Patents

Procedimiento para la preparacion de 2-bromo-6-fluor-n-2-imidazolidiniliden-benzamina y sus sales por adicion de acido

Info

Publication number: MX4841E
Authority: MX; Mexico
Prior art keywords: imidazolidiniliden; benzamina; fluor; bromo; salts
Prior art date: 1976-07-03

Application number

MX775863U

Other languages

English (en)

Inventor

Helmut Stahle

Herbert Koppe

Werner Kummer

Wolfgang Hoefke

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-03

Filing date

1977-07-01

Publication date

1982-10-28

1977-07-01 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1982-10-28 Publication of MX4841E publication Critical patent/MX4841E/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Electric Clocks (AREA)

MX775863U 1976-07-03 1977-07-01 Procedimiento para la preparacion de 2-bromo-6-fluor-n-2-imidazolidiniliden-benzamina y sus sales por adicion de acido MX4841E (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2630060A DE2630060C2 (de)	1976-07-03	1976-07-03	2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung

Publications (1)

Publication Number	Publication Date
MX4841E true MX4841E (es)	1982-10-28

Family

ID=5982175

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MX775863U MX4841E (es)	1976-07-03	1977-07-01	Procedimiento para la preparacion de 2-bromo-6-fluor-n-2-imidazolidiniliden-benzamina y sus sales por adicion de acido

Country Status (32)

Country	Link
US (1)	US4166859A (es)
JP (1)	JPS6026108B2 (es)
AT (1)	AT354436B (es)
AU (1)	AU507260B2 (es)
BE (1)	BE856395A (es)
BG (1)	BG28049A3 (es)
CA (1)	CA1088550A (es)
CH (2)	CH633273A5 (es)
CS (1)	CS204005B2 (es)
DD (1)	DD132965A5 (es)
DE (1)	DE2630060C2 (es)
DK (1)	DK146281C (es)
ES (4)	ES460351A1 (es)
FI (1)	FI64146C (es)
FR (1)	FR2356642B1 (es)
GB (1)	GB1575147A (es)
GR (1)	GR63636B (es)
HU (1)	HU180429B (es)
IE (1)	IE45109B1 (es)
IL (1)	IL52433A (es)
LU (1)	LU77679A1 (es)
MX (1)	MX4841E (es)
NL (2)	NL188643C (es)
NO (2)	NO145951C (es)
NZ (1)	NZ184539A (es)
PH (1)	PH14572A (es)
PL (1)	PL102918B1 (es)
PT (1)	PT66756B (es)
SE (1)	SE431871B (es)
SU (2)	SU680644A3 (es)
YU (1)	YU161977A (es)
ZA (1)	ZA773979B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2806811A1 (de) *	1978-02-17	1979-08-23	Boehringer Sohn Ingelheim	Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
DE2806775A1 (de) *	1978-02-17	1979-08-30	Boehringer Sohn Ingelheim	Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
US4515800A (en) *	1981-11-20	1985-05-07	Icilio Cavero	Method of lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) *	1981-11-20	1984-07-24	Alcon Laboratories, Inc.	2-(Trisubstituted phenylimino)-imidazolines
US4644007A (en) *	1981-11-20	1987-02-17	Alcon Laboratories, Inc.	3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US4517199A (en) *	1981-11-20	1985-05-14	Alcon Laboratories, Inc.	Method for lowering intraocular pressure using phenylimino-imidazoles
DE3437694A1 (de) *	1984-10-15	1986-04-17	Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim	Verwendung einer substanz als sedativum
US4587257A (en) *	1984-12-14	1986-05-06	Alcon Laboratories, Inc.	Control of ocular bleeding using clonidine derivatives
JPH0317363Y2 (es) *	1986-11-19	1991-04-12
US5441339A (en) *	1992-10-22	1995-08-15	Prince Corporation	Vehicle light
WO2005000818A1 (en)	2003-06-27	2005-01-06	Warner-Lambert Company Llc	5-substituted-4-`(substituted phenyl)!amino!-2-pyridone deviatives for use as mek inhibitors
CN115784896A (zh) *	2022-11-24	2023-03-14	山东诚创蓝海医药科技有限公司	一种2-溴-6-氟苯胺的制备方法
CN116063184A (zh) *	2022-12-28	2023-05-05	浙江车头制药股份有限公司	一种2-溴-6-氟苯胺的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1770874B2 (de) *	1968-07-12	1977-09-15	Veb Arzneimittelwerk Dresden, Ddr 8122 Radebeul	Verfahren zur herstellung von 2-(2,6- dichlorphenylamino)-imidazolin-2
BE787683A (fr) *	1971-08-20	1973-02-19	Boehringer Sohn Ingelheim	2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer
DE2446758C3 (de) *	1974-10-01	1979-01-04	C.H. Boehringer Sohn, 6507 Ingelheim	2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie
DE2542702C2 (de) *	1975-09-25	1983-11-10	Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München	Verfahren zur Herstellung von 1-Benzoyl-2-(2,6-dichlorphenylamino)-2-imidazolin

1976
- 1976-07-03 DE DE2630060A patent/DE2630060C2/de not_active Expired
1977
- 1977-06-20 US US05/808,409 patent/US4166859A/en not_active Expired - Lifetime
- 1977-06-22 AT AT438777A patent/AT354436B/de not_active IP Right Cessation
- 1977-06-23 FI FI771972A patent/FI64146C/fi not_active IP Right Cessation
- 1977-06-30 YU YU01619/77A patent/YU161977A/xx unknown
- 1977-06-30 CH CH807577A patent/CH633273A5/fr not_active IP Right Cessation
- 1977-06-30 CA CA281,884A patent/CA1088550A/en not_active Expired
- 1977-06-30 AU AU26620/77A patent/AU507260B2/en not_active Expired
- 1977-07-01 SE SE7707689A patent/SE431871B/xx not_active IP Right Cessation
- 1977-07-01 DK DK296477A patent/DK146281C/da active
- 1977-07-01 BE BE179022A patent/BE856395A/xx not_active IP Right Cessation
- 1977-07-01 IE IE1371/77A patent/IE45109B1/en not_active IP Right Cessation
- 1977-07-01 GB GB27655/77A patent/GB1575147A/en not_active Expired
- 1977-07-01 DD DD7700199844A patent/DD132965A5/xx unknown
- 1977-07-01 NO NO772329A patent/NO145951C/no unknown
- 1977-07-01 CS CS774397A patent/CS204005B2/cs unknown
- 1977-07-01 NL NLAANVRAGE7707308,A patent/NL188643C/xx not_active IP Right Cessation
- 1977-07-01 SU SU772498148A patent/SU680644A3/ru active
- 1977-07-01 JP JP52077979A patent/JPS6026108B2/ja not_active Expired
- 1977-07-01 GR GR53854A patent/GR63636B/el unknown
- 1977-07-01 NZ NZ184539A patent/NZ184539A/xx unknown
- 1977-07-01 PL PL1977199298A patent/PL102918B1/pl unknown
- 1977-07-01 FR FR7720343A patent/FR2356642B1/fr not_active Expired
- 1977-07-01 MX MX775863U patent/MX4841E/es unknown
- 1977-07-01 HU HU77BO1672A patent/HU180429B/hu unknown
- 1977-07-01 IL IL52433A patent/IL52433A/xx unknown
- 1977-07-01 PH PH19947A patent/PH14572A/en unknown
- 1977-07-01 ZA ZA00773979A patent/ZA773979B/xx unknown
- 1977-07-01 PT PT66756A patent/PT66756B/pt unknown
- 1977-07-01 LU LU77679A patent/LU77679A1/xx unknown
- 1977-07-01 BG BG036775A patent/BG28049A3/xx unknown
- 1977-07-02 ES ES460351A patent/ES460351A1/es not_active Expired
1978
- 1978-02-10 ES ES466851A patent/ES466851A1/es not_active Expired
- 1978-02-10 ES ES466850A patent/ES466850A1/es not_active Expired
- 1978-02-10 ES ES466852A patent/ES466852A1/es not_active Expired
- 1978-03-07 SU SU782589253A patent/SU665800A3/ru active
1981
- 1981-09-02 CH CH566381A patent/CH633275A5/de not_active IP Right Cessation
1993
- 1993-06-29 NL NL930111C patent/NL930111I2/nl unknown
1994
- 1994-11-25 NO NO1994024C patent/NO1994024I1/no unknown

Also Published As

Publication number	Publication date
IL52433A0 (en)	1977-10-31
PT66756B (de)	1979-06-07
JPS6026108B2 (ja)	1985-06-21
DD132965A5 (de)	1978-11-22
IE45109B1 (en)	1982-06-16
US4166859A (en)	1979-09-04
PT66756A (de)	1977-08-01
GB1575147A (en)	1980-09-17
CH633273A5 (de)	1982-11-30
AU507260B2 (en)	1980-02-07
ATA438777A (de)	1979-06-15
GR63636B (en)	1979-11-27
LU77679A1 (es)	1978-09-14
IL52433A (en)	1980-09-16
ZA773979B (en)	1979-03-28
DK296477A (da)	1978-01-04
BG28049A3 (en)	1980-02-25
PH14572A (en)	1981-09-24
CH633275A5 (de)	1982-11-30
NL188643C (nl)	1992-08-17
NZ184539A (en)	1980-03-05
DK146281C (da)	1984-01-30
DE2630060C2 (de)	1984-04-19
AT354436B (de)	1979-01-10
SU665800A3 (ru)	1979-05-30
DE2630060A1 (de)	1978-01-12
SE7707689L (sv)	1978-01-04
SU680644A3 (ru)	1979-08-15
NL930111I1 (nl)	1993-10-18
NO145951B (no)	1982-03-22
PL102918B1 (pl)	1979-05-31
NL188643B (nl)	1992-03-16
NO145951C (no)	1982-06-30
HU180429B (en)	1983-03-28
FI771972A (es)	1978-01-04
NL930111I2 (nl)	1995-04-03
IE45109L (en)	1978-01-03
BE856395A (fr)	1978-01-02
AU2662077A (en)	1979-01-04
JPS535164A (en)	1978-01-18
ES466852A1 (es)	1978-10-01
FI64146B (fi)	1983-06-30
YU161977A (en)	1983-01-21
ES466850A1 (es)	1978-10-01
PL199298A1 (pl)	1978-03-28
NO1994024I1 (no)	1994-11-25
ES466851A1 (es)	1978-10-01
NL7707308A (nl)	1978-01-05
SE431871B (sv)	1984-03-05
CS204005B2 (en)	1981-03-31
DK146281B (da)	1983-08-22
FR2356642A1 (fr)	1978-01-27
ES460351A1 (es)	1978-08-16
CA1088550A (en)	1980-10-28
NO772329L (no)	1978-01-03
FR2356642B1 (fr)	1985-07-19
FI64146C (fi)	1983-10-10

Similar Documents

Publication	Publication Date	Title
MX6091E (es)	1984-11-12	Proceso para la preparacion de derivados aminicos de di-o-(n-alquil superior)-gliceroles y sus sales de adicion de acido
AR209457A1 (es)	1977-04-29	Procedimiento para la preparacion de nuevas sales de biguanidas
AR226285A1 (es)	1982-06-30	Procedimiento para la preparacion de 2-aril-aminotiazoles y sus sales de adicion de acidos farmaceuticamente aceptables
AR222828A1 (es)	1981-06-30	Procedimiento para la preparacion de 2,3,4,5-tetrahidro-6-feniltio-1h-3-benzazepinas y sus sales
MX5477E (es)	1983-08-19	Procedimiento para la preparacion de derivados de acido pseudomonico
ES494668A0 (es)	1981-08-16	Procedimiento para la preparacion de sales de la (+)-cate- quina
AR208538A1 (es)	1977-02-15	Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-ol-4-carboxilico y sus sales
AR215162A1 (es)	1979-09-14	Procedimiento mejorado para la preparacion de acido d,1-5-metiltetrahidrofolico y sus sales
MX4841E (es)	1982-10-28	Procedimiento para la preparacion de 2-bromo-6-fluor-n-2-imidazolidiniliden-benzamina y sus sales por adicion de acido
AR211031A1 (es)	1977-10-14	Un procedimiento para la preparacion de acido clavulanico y sus sales.
AR212468A1 (es)	1978-07-14	Procedimiento para la preparacion de nuevos derivados de w-alquilamidas de acidos w amino-carboxilicos y sus sales
AR227272A1 (es)	1982-10-15	Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza y sus sales
AR228019A1 (es)	1983-01-14	Procedimiento para preparar derivados de acidos-(3-fenoxi-2-amino)-fenilalcanoicos y sus sales
MX5006E (es)	1983-02-09	Procedimiento para la preparacion de acido ciclohexancarboxilico
AR218951A1 (es)	1980-07-15	Procedimiento para obtener derivados de acidos 3-(1-metiltetrazolil-tiometil)-7-glicilamido-1-oxadetia-3-cefem-4-carboxilicos y sus sales
MX4950E (es)	1983-01-12	Procedimiento para la preparacion de tioesteres de acido clavulanico
AR226180A1 (es)	1982-06-15	Procedimiento para la sintesis de acido 4,4'-dinitroestilben-2,2'-disulfonico y sus sales
AR220904A1 (es)	1980-12-15	Procedimiento para la produccion de 8,8a-desoxi-8-aminometiloleandomicinas,sus monoesteres y diesteres c2-c3 en las posiciones 4"y/o ii de las mismas,y sus sales de adicion de acido
MX4914E (es)	1983-01-03	Procedimiento mejorado para la produccion de acido metacrilico
AR224610A1 (es)	1981-12-30	Procedimiento para obtener derivados,de acidos benzacil-benzimidazol-2-carboxilicos o de 2-hidroximetilo y sus sales
AR226288A1 (es)	1982-06-30	Procedimiento para la produccion de nuevas 4-alquiltiofenoxi alquilaminas y sus sales
MX4601E (es)	1982-06-25	Procedimiento para la preparacion de esteres bencilicos de acido 2-isoprofil-4-fenil-3-butenico
AR214985A1 (es)	1979-08-31	Procedimiento para la elaboracion de 4-7-bromo-5-metoxi-2-benzofuranil)-piperidina y sus sales de adicion de acidos
MX3845E (es)	1981-08-18	Procedimiento para la preparacion de sulfoximidas substituidas y sus sales
MX4818E (es)	1982-10-20	Procedimiento para la preparacion de amidas de acidos(2-pirimidiniltio)alcanoicos