MX363944B - Método de preparación de los compuestos de ceramidas de alfa-galactosilo. - Google Patents
Método de preparación de los compuestos de ceramidas de alfa-galactosilo.Info
- Publication number
- MX363944B MX363944B MX2015005592A MX2015005592A MX363944B MX 363944 B MX363944 B MX 363944B MX 2015005592 A MX2015005592 A MX 2015005592A MX 2015005592 A MX2015005592 A MX 2015005592A MX 363944 B MX363944 B MX 363944B
- Authority
- MX
- Mexico
- Prior art keywords
- alphagalactosyl
- preparation
- ceramides
- compounds
- ceramides compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/06—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La presente invención se relaciona con un método de preparación de los compuestos de ceramidas de a-galactosilo de la fórmula (I), que comprende una etapa a) de glicosilación de un compuesto de la fórmula (II) con un compuesto de la fórmula (III).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261720098P | 2012-10-30 | 2012-10-30 | |
EP12306355.4A EP2727929A1 (en) | 2012-10-30 | 2012-10-30 | Method of preparation of alpha galactosyl ceramides compounds |
PCT/EP2013/072711 WO2014067995A1 (en) | 2012-10-30 | 2013-10-30 | METHOD OF PREPARATION OF α-GALACTOSYL CERAMIDES COMPOUNDS |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015005592A MX2015005592A (es) | 2016-06-02 |
MX363944B true MX363944B (es) | 2019-04-09 |
Family
ID=47172560
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015005592A MX363944B (es) | 2012-10-30 | 2013-10-30 | Método de preparación de los compuestos de ceramidas de alfa-galactosilo. |
Country Status (23)
Country | Link |
---|---|
US (1) | US10870671B2 (es) |
EP (2) | EP2727929A1 (es) |
JP (1) | JP6140830B2 (es) |
CN (2) | CN104812769A (es) |
AR (1) | AR093270A1 (es) |
AU (1) | AU2013340901B2 (es) |
BR (1) | BR112015009720B1 (es) |
CA (1) | CA2888391C (es) |
CU (1) | CU24311B1 (es) |
CY (1) | CY1119697T1 (es) |
DK (1) | DK2920194T3 (es) |
ES (1) | ES2655655T3 (es) |
HR (1) | HRP20171687T1 (es) |
HU (1) | HUE035530T2 (es) |
IL (1) | IL238515B (es) |
LT (1) | LT2920194T (es) |
MX (1) | MX363944B (es) |
PL (1) | PL2920194T3 (es) |
PT (1) | PT2920194T (es) |
RU (1) | RU2662156C2 (es) |
SI (1) | SI2920194T1 (es) |
WO (1) | WO2014067995A1 (es) |
ZA (1) | ZA201502844B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2021526533A (ja) * | 2018-06-15 | 2021-10-07 | カーボコード エス.エー.Carbocode S.A. | グリコシル化されたスフィンゴイド塩基およびその製造 |
CN110479184B (zh) * | 2019-08-05 | 2021-09-07 | 华侨大学 | 一种琼脂糖基乳化剂及其制备方法和应用 |
CA3212136A1 (en) | 2021-03-01 | 2022-09-09 | Deciduous Therapeutics, Inc. | Compounds for activating invariant natural killer t-cells and methods of use in eliminating inflammatory senescent cells |
WO2024050020A1 (en) * | 2022-08-31 | 2024-03-07 | Deciduous Therapeutics, Inc. | Invariant natural killer t-cell activators |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE758395A (fr) * | 1969-11-03 | 1971-05-03 | Upjohn Co | Procede de conversion d'halogenures de cis-glucosyle peracyles et nouveaux composes en derivant |
US4310505A (en) * | 1979-11-08 | 1982-01-12 | California Institute Of Technology | Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances |
FR2711138B1 (fr) | 1993-10-12 | 1995-11-24 | Oreal | Céramides, leur procédé de préparation et leurs applications en cosmétique et en dermopharmacie. |
CN1405172A (zh) | 2001-08-13 | 2003-03-26 | 青岛海洋大学 | 一种乳糖胺脂及其制备方法和应用 |
CN101331146B (zh) * | 2005-10-25 | 2012-06-13 | 路德维格癌症研究院 | α-半乳糖神经酰胺的类似物及其用途 |
US8227581B2 (en) | 2006-04-07 | 2012-07-24 | The Scripps Research Institute | Modified α-galactosyl ceramides for staining and stimulating natural killer T cells |
CN101012254A (zh) | 2006-08-29 | 2007-08-08 | 中国海洋大学 | 一种α-半乳糖鞘糖脂的2’-OH衍生物及其制备方法 |
AU2012204336C1 (en) * | 2011-01-05 | 2017-08-03 | National Taiwan University | Methods for preparation of glycosphingolipids and uses thereof |
-
2012
- 2012-10-30 EP EP12306355.4A patent/EP2727929A1/en not_active Withdrawn
-
2013
- 2013-10-30 RU RU2015116422A patent/RU2662156C2/ru active
- 2013-10-30 ES ES13783936.1T patent/ES2655655T3/es active Active
- 2013-10-30 CA CA2888391A patent/CA2888391C/en active Active
- 2013-10-30 AU AU2013340901A patent/AU2013340901B2/en active Active
- 2013-10-30 CN CN201380056606.0A patent/CN104812769A/zh active Pending
- 2013-10-30 PL PL13783936T patent/PL2920194T3/pl unknown
- 2013-10-30 DK DK13783936.1T patent/DK2920194T3/en active
- 2013-10-30 US US14/439,642 patent/US10870671B2/en active Active
- 2013-10-30 EP EP13783936.1A patent/EP2920194B1/en active Active
- 2013-10-30 LT LTEP13783936.1T patent/LT2920194T/lt unknown
- 2013-10-30 CN CN201811555848.5A patent/CN109503682B/zh active Active
- 2013-10-30 CU CUP2015000042A patent/CU24311B1/es unknown
- 2013-10-30 MX MX2015005592A patent/MX363944B/es active IP Right Grant
- 2013-10-30 PT PT137839361T patent/PT2920194T/pt unknown
- 2013-10-30 WO PCT/EP2013/072711 patent/WO2014067995A1/en active Application Filing
- 2013-10-30 AR ARP130103950A patent/AR093270A1/es active IP Right Grant
- 2013-10-30 SI SI201330907T patent/SI2920194T1/en unknown
- 2013-10-30 BR BR112015009720-0A patent/BR112015009720B1/pt active IP Right Grant
- 2013-10-30 JP JP2015538504A patent/JP6140830B2/ja active Active
- 2013-10-30 HU HUE13783936A patent/HUE035530T2/en unknown
-
2015
- 2015-04-24 ZA ZA2015/02844A patent/ZA201502844B/en unknown
- 2015-04-28 IL IL238515A patent/IL238515B/en active IP Right Grant
-
2017
- 2017-11-06 HR HRP20171687TT patent/HRP20171687T1/hr unknown
- 2017-12-18 CY CY20171101324T patent/CY1119697T1/el unknown
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