MX363201B - Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico. - Google Patents
Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico.Info
- Publication number
- MX363201B MX363201B MX2013010127A MX2013010127A MX363201B MX 363201 B MX363201 B MX 363201B MX 2013010127 A MX2013010127 A MX 2013010127A MX 2013010127 A MX2013010127 A MX 2013010127A MX 363201 B MX363201 B MX 363201B
- Authority
- MX
- Mexico
- Prior art keywords
- determining
- pancreatic cancer
- array
- individual
- test sample
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5406—IL-4
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5412—IL-6
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/5437—IL-13
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La presente invención se refiere a un procedimiento para determinar la presencia de cáncer pancreático en un individuo, que comprende o consiste en las etapas de: (a) proporcionar una muestra a ensayar del individuo y (b) determinar una firma biomarcadora de la muestra de ensayo midiendo la expresión en la muestra de ensayo de uno o más biomarcadores seleccionados del grupo definido en la Tabla III, en el que la expresión en la muestra de ensayo de uno o más biomarcadores seleccionados del grupo definido en la Tabla III es indicativa del cáncer pancreático que padece el individuo. La invención también comprende matrices y kits de partes para su uso en el procedimiento de la invención.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1103726.4A GB201103726D0 (en) | 2011-03-04 | 2011-03-04 | Method, array and use thereof |
PCT/GB2012/050483 WO2012120288A2 (en) | 2011-03-04 | 2012-03-05 | Method, array and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013010127A MX2013010127A (es) | 2014-10-15 |
MX363201B true MX363201B (es) | 2019-03-14 |
Family
ID=43923218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013010127A MX363201B (es) | 2011-03-04 | 2012-03-05 | Procedimiento, matriz y uso para determinar la presencia de cancer pancreatico. |
Country Status (9)
Country | Link |
---|---|
US (4) | US9863960B2 (es) |
EP (1) | EP2681563A2 (es) |
JP (1) | JP6161542B2 (es) |
KR (2) | KR20190101489A (es) |
CN (2) | CN103534594A (es) |
CA (1) | CA2828338A1 (es) |
GB (1) | GB201103726D0 (es) |
MX (1) | MX363201B (es) |
WO (1) | WO2012120288A2 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008117067A2 (en) | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
GB201103726D0 (en) | 2011-03-04 | 2011-04-20 | Immunovia Ab | Method, array and use thereof |
GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
KR101658164B1 (ko) * | 2014-04-28 | 2016-09-21 | 서강대학교산학협력단 | 브롬 동위원소 신호를 이용한 자유 라디칼-개시 펩타이드 시퀀싱 질량분석 |
KR20150129932A (ko) | 2014-05-12 | 2015-11-23 | 연세대학교 산학협력단 | 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트 |
CN105572276B (zh) * | 2014-11-07 | 2018-12-18 | 上海市第六人民医院 | 胰腺癌诊断标记物组合、应用及其测定方法 |
CN104698170A (zh) * | 2015-03-17 | 2015-06-10 | 任传利 | Il-11作为生物标记物在胰腺癌诊断和预后评价的方法 |
EP3073268A1 (en) * | 2015-03-27 | 2016-09-28 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Biomarker panel for diagnosing cancer |
JP5852759B1 (ja) * | 2015-04-01 | 2016-02-03 | 株式会社キュービクス | 遺伝子発現解析による膵臓癌の検出 |
GB201516801D0 (en) | 2015-09-22 | 2015-11-04 | Immunovia Ab | Method, array and use thereof |
JP5970123B1 (ja) * | 2015-12-04 | 2016-08-17 | 株式会社キュービクス | 遺伝子発現解析による膵臓癌の検出 |
JP6392201B2 (ja) * | 2015-12-04 | 2018-09-19 | 株式会社キュービクス | 遺伝子発現解析による膵臓癌の検出 |
KR101594287B1 (ko) | 2016-01-13 | 2016-02-15 | 연세대학교 산학협력단 | 보체인자 b 단백질에 특이적으로 결합하는 항체를 포함하는 췌장암 진단용 키트 |
WO2017133746A1 (en) * | 2016-02-05 | 2017-08-10 | Dana Genetic A/S | Method for diagnosing and treating cancer using antibodies that bind to c1 inactivator, c reactive protein and/or complement component c4 |
GB201608192D0 (en) * | 2016-05-10 | 2016-06-22 | Immunovia Ab | Method, array and use thereof |
DE202017007364U1 (de) | 2016-12-16 | 2021-02-11 | The Brigham And Women's Hospital Inc. | Anordnung markierter Sensorelemente zum Erfassen unterschiedlicher Proteine, die unterschiedliche Sensorelemente binden |
US20210072255A1 (en) | 2016-12-16 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | System and method for protein corona sensor array for early detection of diseases |
GB201701572D0 (en) | 2017-01-31 | 2017-03-15 | Immunovia Ab | Methods, arrays and uses thereof |
KR102536314B1 (ko) * | 2018-05-23 | 2023-05-25 | 주식회사 휴벳바이오 | 질환의 진단용 조성물 |
CN113412274A (zh) | 2018-11-07 | 2021-09-17 | 禧尔公司 | 用于蛋白质冠分析的组合物、方法和系统及其用途 |
WO2020169511A1 (en) | 2019-02-18 | 2020-08-27 | The University Of Liverpool | Method of diagnosis |
IL303893A (en) | 2019-08-05 | 2023-08-01 | Seer Inc | Systems and methods for sample preparation, data generation and corona protein analysis |
GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
CN113655144A (zh) * | 2021-08-09 | 2021-11-16 | 大连医科大学附属第一医院 | 一种基于丙酮酸激酶和α-2-HS-糖蛋白的早期预警重症急性胰腺炎的预测模型 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
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DE3169789D1 (en) | 1980-05-02 | 1985-05-15 | Edward P Davis | Leg aid device |
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
US5856090A (en) | 1994-09-09 | 1999-01-05 | The Scripps Research Institute | DNA-methylase linking reaction |
GB9703369D0 (en) | 1997-02-18 | 1997-04-09 | Lindqvist Bjorn H | Process |
JP4194080B2 (ja) | 2003-02-19 | 2008-12-10 | 茂 森村 | 膵癌検出用マーカー |
US20050277137A1 (en) * | 2003-08-15 | 2005-12-15 | University Of Pittsburgh | Diagnostic multimarker serological profiling |
US20060106119A1 (en) | 2004-01-12 | 2006-05-18 | Chang-Jie Guo | Novel integration for CO and H2 recovery in gas to liquid processes |
JP2008514205A (ja) * | 2004-09-29 | 2008-05-08 | 財団法人実験動物中央研究所 | Nogマウスを用いた高転移性細胞株の樹立 |
US8383357B2 (en) | 2005-03-16 | 2013-02-26 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to epidermal growth factor receptor kinase inhibitors |
CA2604885A1 (en) | 2005-04-07 | 2006-10-19 | Guoying Yu | Cacna1e in cancer diagnosis, detection and treatment |
WO2006110585A2 (en) | 2005-04-07 | 2006-10-19 | Novartis Vaccines And Diagnostics Inc. | Cancer-related genes (prlr) |
JP2007051880A (ja) | 2005-08-15 | 2007-03-01 | Tokyo Univ Of Science | 膵臓癌の検出方法、膵臓癌の診断キット |
WO2007107774A2 (en) | 2006-03-22 | 2007-09-27 | Cartela R & D Ab | Integrin alpha-10 subunit as therapeutic target and diagnostic/prognostic marker for cancer |
KR100819122B1 (ko) * | 2006-09-30 | 2008-04-04 | 남명진 | 췌장암 진단용 키트 |
WO2008079269A2 (en) | 2006-12-19 | 2008-07-03 | Genego, Inc. | Novel methods for functional analysis of high-throughput experimental data and gene groups identified therfrom |
WO2008117067A2 (en) * | 2007-03-27 | 2008-10-02 | Carl Arne Krister Borrebaeck | Protein signature/markers for the detection of adenocarcinoma |
GB0723179D0 (en) * | 2007-11-27 | 2008-01-02 | Immunovia Ab | Diagnostic methods and arrays for use in the same |
CN102203295A (zh) * | 2008-09-03 | 2011-09-28 | 约翰霍普金斯大学 | 胰腺肿瘤发生的通路及遗传性胰腺癌基因 |
WO2010102195A2 (en) * | 2009-03-06 | 2010-09-10 | The Johns Hopkins University | Annexin a11 and associated genes as biomarkers for cancer |
CN101880707A (zh) * | 2009-05-05 | 2010-11-10 | 中国人民解放军第二军医大学 | microRNA-21在鉴别胰腺癌中的应用 |
CN101613748A (zh) * | 2009-06-09 | 2009-12-30 | 中国人民解放军第二军医大学 | 一种检测胰腺癌血清标志物的方法 |
SG168431A1 (en) * | 2009-07-23 | 2011-02-28 | Univ Singapore | Cancer biomarker and the use thereof |
GB201103726D0 (en) | 2011-03-04 | 2011-04-20 | Immunovia Ab | Method, array and use thereof |
GB201319878D0 (en) | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
-
2011
- 2011-03-04 GB GBGB1103726.4A patent/GB201103726D0/en not_active Ceased
-
2012
- 2012-03-05 CN CN201280021793.4A patent/CN103534594A/zh active Pending
- 2012-03-05 WO PCT/GB2012/050483 patent/WO2012120288A2/en active Application Filing
- 2012-03-05 US US14/002,494 patent/US9863960B2/en active Active
- 2012-03-05 CN CN201710061429.5A patent/CN107064518A/zh active Pending
- 2012-03-05 JP JP2013555939A patent/JP6161542B2/ja not_active Expired - Fee Related
- 2012-03-05 MX MX2013010127A patent/MX363201B/es unknown
- 2012-03-05 KR KR1020197024469A patent/KR20190101489A/ko not_active Application Discontinuation
- 2012-03-05 KR KR1020137026248A patent/KR102014890B1/ko active IP Right Grant
- 2012-03-05 CA CA2828338A patent/CA2828338A1/en not_active Abandoned
- 2012-03-05 EP EP12719425.6A patent/EP2681563A2/en not_active Ceased
-
2017
- 2017-08-23 US US15/684,090 patent/US20180136231A1/en not_active Abandoned
-
2019
- 2019-11-26 US US16/695,397 patent/US20200088742A1/en not_active Abandoned
-
2021
- 2021-07-22 US US17/382,613 patent/US20210356478A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20180136231A1 (en) | 2018-05-17 |
CN107064518A (zh) | 2017-08-18 |
US9863960B2 (en) | 2018-01-09 |
US20210356478A1 (en) | 2021-11-18 |
EP2681563A2 (en) | 2014-01-08 |
JP2014508298A (ja) | 2014-04-03 |
US20140038844A1 (en) | 2014-02-06 |
MX2013010127A (es) | 2014-10-15 |
KR20140040118A (ko) | 2014-04-02 |
US20200088742A1 (en) | 2020-03-19 |
KR102014890B1 (ko) | 2019-08-27 |
WO2012120288A3 (en) | 2013-01-10 |
WO2012120288A2 (en) | 2012-09-13 |
GB201103726D0 (en) | 2011-04-20 |
JP6161542B2 (ja) | 2017-07-12 |
CA2828338A1 (en) | 2012-09-13 |
CN103534594A (zh) | 2014-01-22 |
KR20190101489A (ko) | 2019-08-30 |
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