MX362905B - Tratamiento de combinacion. - Google Patents
Tratamiento de combinacion.Info
- Publication number
- MX362905B MX362905B MX2015011588A MX2015011588A MX362905B MX 362905 B MX362905 B MX 362905B MX 2015011588 A MX2015011588 A MX 2015011588A MX 2015011588 A MX2015011588 A MX 2015011588A MX 362905 B MX362905 B MX 362905B
- Authority
- MX
- Mexico
- Prior art keywords
- taxane
- pharmaceutically acceptable
- acceptable salt
- compound
- treatment
- Prior art date
Links
- 238000011284 combination treatment Methods 0.000 title 1
- 229940123237 Taxane Drugs 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000011282 treatment Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Abstract
La presente invención se refiere al uso de combinaciones que comprenden 8-[(1R)-1-(3,5-difluorofenilamino)etil]-N,N-dimetil-2-m orfolino-4-oxo-4H-cromeno-6-carboxamida o una sal farmacéuticamente aceptable de la misma y un taxano en el tratamiento o profilaxis de cáncer; composiciones farmacéuticas que comprenden el Compuesto [I] (o una sal farmacéuticamente aceptable del mismo) y un taxano; kits que comprenden el Compuesto [I] o una sal farmacéuticamente aceptable del mismo y un taxano, opcionalmente con instrucciones para su uso; y métodos de tratamiento que comprenden la administración simultánea, secuencial o separada del Compuesto [I] o una sal farmacéuticamente aceptable del mismo y un taxano a un animal de sangre caliente, tal como el hombre.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361771974P | 2013-03-04 | 2013-03-04 | |
| US201361772079P | 2013-03-04 | 2013-03-04 | |
| PCT/GB2014/050618 WO2014135851A1 (en) | 2013-03-04 | 2014-03-03 | Combination treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015011588A MX2015011588A (es) | 2015-12-09 |
| MX362905B true MX362905B (es) | 2019-02-25 |
Family
ID=50288179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015011588A MX362905B (es) | 2013-03-04 | 2014-03-03 | Tratamiento de combinacion. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9763950B2 (es) |
| EP (1) | EP2964217B1 (es) |
| JP (1) | JP6546098B2 (es) |
| KR (1) | KR102222346B1 (es) |
| CN (1) | CN105142629B (es) |
| AU (1) | AU2014224445C1 (es) |
| BR (1) | BR112015019524A8 (es) |
| CA (1) | CA2900136C (es) |
| ES (1) | ES2754034T3 (es) |
| HK (1) | HK1216391A1 (es) |
| MX (1) | MX362905B (es) |
| RU (1) | RU2666999C2 (es) |
| WO (1) | WO2014135851A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| EP3765035A4 (en) * | 2018-03-16 | 2021-10-27 | DFB Soria, LLC | TOPICAL THERAPY FOR TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) AND ETERNAL CANCER USING TAXANNANO PARTICLES |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT58310A (en) | 1988-12-21 | 1992-02-28 | Upjohn Co | Anti-atherosclerotic and anti-thrombotic 1-benzopyran-4-one- and 2-amino-1,3-benzoxazin-4-one derivatives, process for producing them and pharmaceutical compositions containing them |
| US5439686A (en) | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
| US6749868B1 (en) | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| PT1023050E (pt) | 1997-06-27 | 2013-12-04 | Abraxis Bioscience Llc | Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização |
| US6395300B1 (en) | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| RU2284818C2 (ru) * | 2001-05-10 | 2006-10-10 | Анормед, Инк. | Комбинированная химиотерапия |
| EP1537102A4 (en) | 2002-08-16 | 2010-12-08 | Astrazeneca Ab | INHIBITORS OF PHOSPHOINOSITIDE-3-KINASE BETA |
| DE602004024115D1 (de) | 2003-12-09 | 2009-12-24 | Us Gov Health & Human Serv | Verfahren zur unterdrückung einer immunantwort oder zur behandlung von proliferativen erkrankungen |
| CA2620389C (en) | 2005-08-31 | 2014-06-17 | Abraxis Bioscience, Llc | Compositions and methods for preparation of poorly water soluble drugs with increased stability |
| EP2399573B1 (en) | 2005-08-31 | 2019-01-02 | Abraxis BioScience, LLC | Compositions comprising poorly water soluble pharmaceutical agents |
| WO2008064244A2 (en) | 2006-11-20 | 2008-05-29 | The Trustees Of Columbia University In The City Of New York | Phosphoinositide modulation for the treatment of neurodegenerative diseases |
| RU2438664C2 (ru) * | 2007-05-15 | 2012-01-10 | Пирамал Лайф Сайнсиз Лимитед | Синергическая фармацевтическая комбинация для лечения рака |
| US8399460B2 (en) * | 2009-10-27 | 2013-03-19 | Astrazeneca Ab | Chromenone derivatives |
| US9402847B2 (en) * | 2011-04-01 | 2016-08-02 | Astrazeneca Ab | Combinations comprising (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide |
-
2014
- 2014-03-03 AU AU2014224445A patent/AU2014224445C1/en not_active Ceased
- 2014-03-03 JP JP2015560763A patent/JP6546098B2/ja not_active Expired - Fee Related
- 2014-03-03 US US14/772,472 patent/US9763950B2/en active Active
- 2014-03-03 ES ES14710617T patent/ES2754034T3/es active Active
- 2014-03-03 BR BR112015019524A patent/BR112015019524A8/pt active Search and Examination
- 2014-03-03 CN CN201480008510.1A patent/CN105142629B/zh active Active
- 2014-03-03 KR KR1020157022944A patent/KR102222346B1/ko active IP Right Grant
- 2014-03-03 WO PCT/GB2014/050618 patent/WO2014135851A1/en active Application Filing
- 2014-03-03 EP EP14710617.3A patent/EP2964217B1/en active Active
- 2014-03-03 MX MX2015011588A patent/MX362905B/es active IP Right Grant
- 2014-03-03 RU RU2015139515A patent/RU2666999C2/ru active
- 2014-03-03 CA CA2900136A patent/CA2900136C/en active Active
-
2016
- 2016-04-18 HK HK16104366.0A patent/HK1216391A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20160022690A1 (en) | 2016-01-28 |
| KR102222346B1 (ko) | 2021-03-02 |
| EP2964217A1 (en) | 2016-01-13 |
| KR20150122145A (ko) | 2015-10-30 |
| ES2754034T3 (es) | 2020-04-15 |
| US9763950B2 (en) | 2017-09-19 |
| EP2964217B1 (en) | 2019-08-28 |
| CA2900136C (en) | 2021-05-04 |
| AU2014224445B2 (en) | 2017-02-02 |
| MX2015011588A (es) | 2015-12-09 |
| CA2900136A1 (en) | 2014-09-12 |
| RU2666999C2 (ru) | 2018-09-13 |
| CN105142629B (zh) | 2018-11-23 |
| JP2016510060A (ja) | 2016-04-04 |
| WO2014135851A1 (en) | 2014-09-12 |
| JP6546098B2 (ja) | 2019-07-17 |
| RU2015139515A (ru) | 2017-04-10 |
| AU2014224445C1 (en) | 2017-07-27 |
| CN105142629A (zh) | 2015-12-09 |
| AU2014224445A1 (en) | 2015-08-27 |
| BR112015019524A2 (pt) | 2017-07-18 |
| HK1216391A1 (zh) | 2016-11-11 |
| BR112015019524A8 (pt) | 2019-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |