[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

MX368970B - Formulacion de factor de crecimiento de fibroblastos 18 en hidrogeles de alginato/colageno. - Google Patents

Formulacion de factor de crecimiento de fibroblastos 18 en hidrogeles de alginato/colageno.

Info

Publication number
MX368970B
MX368970B MX2016008442A MX2016008442A MX368970B MX 368970 B MX368970 B MX 368970B MX 2016008442 A MX2016008442 A MX 2016008442A MX 2016008442 A MX2016008442 A MX 2016008442A MX 368970 B MX368970 B MX 368970B
Authority
MX
Mexico
Prior art keywords
fgf
hydrogels
alginate
formulation
collagen hydrogels
Prior art date
Application number
MX2016008442A
Other languages
English (en)
Other versions
MX2016008442A (es
Inventor
CANAL Fabiana
Lo Presti Caterina
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of MX2016008442A publication Critical patent/MX2016008442A/es
Publication of MX368970B publication Critical patent/MX368970B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/505—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Polymers & Plastics (AREA)

Abstract

La presente invención se refiere al campo de las formulaciones farmacéuticas; más en particular, está dirigida a hidrogeles homogéneos que comprenden un compuesto de factor de crecimiento de fibroblasto 18 (FGF-18) y a métodos de producción de dichos hidrogeles; los hidrogeles de la invención se pueden usar, una vez formados in situ, para el tratamiento de trastornos del cartílago como osteoartritis o lesión del cartílago.
MX2016008442A 2013-12-24 2014-12-23 Formulacion de factor de crecimiento de fibroblastos 18 en hidrogeles de alginato/colageno. MX368970B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13199591 2013-12-24
PCT/EP2014/079205 WO2015097236A2 (en) 2013-12-24 2014-12-23 Fgf-18 formulation in alginate/collagen hydrogels

Publications (2)

Publication Number Publication Date
MX2016008442A MX2016008442A (es) 2017-01-11
MX368970B true MX368970B (es) 2019-10-23

Family

ID=49882942

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016008442A MX368970B (es) 2013-12-24 2014-12-23 Formulacion de factor de crecimiento de fibroblastos 18 en hidrogeles de alginato/colageno.

Country Status (17)

Country Link
US (1) US9795714B2 (es)
EP (1) EP3086822B1 (es)
JP (1) JP6487448B2 (es)
KR (1) KR102434024B1 (es)
CN (1) CN106068131B (es)
AU (1) AU2014372578B2 (es)
BR (1) BR112016014717B1 (es)
CA (1) CA2934638C (es)
ES (1) ES2806026T3 (es)
HK (1) HK1225657A1 (es)
IL (1) IL246407B (es)
MX (1) MX368970B (es)
NZ (1) NZ721597A (es)
RU (1) RU2698210C2 (es)
SG (1) SG11201604972TA (es)
WO (1) WO2015097236A2 (es)
ZA (1) ZA201604610B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105103654B (zh) 2013-02-14 2017-06-23 纳米帕雷尔股份有限公司 纳米纤维混合毛毡
CN106029085B (zh) 2013-12-24 2020-08-04 阿雷斯贸易股份有限公司 木糖葡聚糖凝胶中的fgf-18制剂
SI3107592T1 (sl) * 2014-02-20 2018-11-30 Merck Patent Gmbh Implantat, ki obsega FGF-18
US10408686B2 (en) * 2016-01-15 2019-09-10 Temptime Corporation Gel-based temperature indicators
EP3821920A4 (en) * 2018-07-13 2022-03-02 T-ACE Medical Co., Ltd. SUIT FOR ENDOSCOPIC SURGERY
WO2020032221A1 (ja) * 2018-08-10 2020-02-13 持田製薬株式会社 アルギン酸中空マイクロファイバ
US20210369875A1 (en) * 2018-11-06 2021-12-02 National Cancer Center Alginic acid-based injectable hydrogel system
CN111068116B (zh) * 2019-12-28 2022-03-22 河北柯瑞生物医药有限公司 一种注射用软骨修复温敏凝胶及其制备方法
EP4149576A1 (en) * 2020-05-14 2023-03-22 Institut National De La Sante Et De La Recherche Medicale - Inserm Composite product for the osteoarticular regeneration of cartilage lesion
CN112263505A (zh) * 2020-10-29 2021-01-26 广州栋方生物科技股份有限公司 一种铜肽组合物及其制备方法和应用
CN115990244A (zh) * 2023-03-10 2023-04-21 温州医科大学慈溪生物医药研究院 重组人成纤维细胞生长因子-18蛋白药物组合物对骨质疏松的作用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2254350A1 (en) 1998-11-17 2000-05-17 Hsc Research And Development Limited Partnership Method for bioengineering cartilage
US6451346B1 (en) * 1998-12-23 2002-09-17 Amgen Inc Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
US6355204B1 (en) * 2000-06-07 2002-03-12 Owens-Brockway Plastic Products Inc. Method of manufacturing a dual-chamber container
ES2523655T5 (es) * 2002-06-21 2018-04-23 Novo Nordisk Health Care Ag Composiciones sólidas estabilizadas de polipéptidos del Factor VIIa
AU2003279835B2 (en) * 2002-10-07 2009-09-10 Zymogenetics, Inc. Methods of administering FGF18
EP1799232B1 (en) 2004-10-12 2015-10-07 FMC Biopolymer AS Self-gelling alginate systems and uses thereof
US8741326B2 (en) * 2006-11-17 2014-06-03 Abbott Cardiovascular Systems Inc. Modified two-component gelation systems, methods of use and methods of manufacture
EP2288370A1 (fr) * 2008-04-14 2011-03-02 Adocia Composition osteogenique comprenant un complexe facteur de croissance/polymere amphiphile un sel soluble de cation e un support organique
JP2011160817A (ja) * 2010-02-04 2011-08-25 Univ Of Tokyo 移植支援材料
WO2012050184A1 (ja) 2010-10-15 2012-04-19 国立大学法人京都大学 徐放性医薬組成物
US10034737B2 (en) * 2011-02-22 2018-07-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nano-reservoirs technology for use in bone and/or cartilage regeneration
TWI527590B (zh) 2011-06-17 2016-04-01 艾瑞斯貿易公司 Ｆｇｆ－１８之凍乾調配物
CN106029085B (zh) 2013-12-24 2020-08-04 阿雷斯贸易股份有限公司 木糖葡聚糖凝胶中的fgf-18制剂

Also Published As

Publication number Publication date
HK1225657A1 (zh) 2017-09-15
RU2016129817A3 (es) 2018-08-24
AU2014372578A1 (en) 2016-07-14
IL246407A0 (en) 2016-08-31
CA2934638A1 (en) 2015-07-02
AU2014372578A2 (en) 2016-11-17
CN106068131A (zh) 2016-11-02
CN106068131B (zh) 2020-01-17
RU2016129817A (ru) 2018-01-30
IL246407B (en) 2020-01-30
NZ721597A (en) 2022-07-01
ZA201604610B (en) 2018-11-28
RU2698210C2 (ru) 2019-08-23
MX2016008442A (es) 2017-01-11
US20160303291A1 (en) 2016-10-20
EP3086822B1 (en) 2020-04-15
JP6487448B2 (ja) 2019-03-20
EP3086822A2 (en) 2016-11-02
WO2015097236A2 (en) 2015-07-02
US9795714B2 (en) 2017-10-24
ES2806026T3 (es) 2021-02-16
KR102434024B1 (ko) 2022-08-22
SG11201604972TA (en) 2016-07-28
BR112016014717B1 (pt) 2020-12-01
BR112016014717A2 (pt) 2017-09-19
WO2015097236A3 (en) 2015-09-17
AU2014372578B2 (en) 2018-03-01
JP2017502042A (ja) 2017-01-19
CA2934638C (en) 2022-07-12
KR20160101163A (ko) 2016-08-24

Similar Documents

Publication Publication Date Title
MX2016008442A (es) Formulacion de factor de crecimiento de fibroblastos 18 en hidrogeles de alginato/colageno.
AU2018260809A1 (en) Compounds and uses thereof for the modulation of hemoglobin
AU2018260808A1 (en) Compounds and uses thereof for the modulation of hemoglobin
MX2017006232A (es) Relleno dermico a base de acido hialuronico reticulado y lubricante de carboximetilcelulosa.
PH12017501956A1 (en) Compositions of obeticholic acid and methods of use
SG10201808104RA (en) Cenicriviroc for the treatment of fibrosis
BR112015024846A2 (pt) composições para utilização no estímulo do crescimento ósseo
MX2015011769A (es) Compuestos y sus usos para modular la hemoglobina.
MX2015011509A (es) Compuestos y usos de estos para la modulacion de la hemoglobina.
EP3318564A3 (en) Bicyclic heterocycles as fgfr inhibitors
MX362215B (es) Derivados 2-aminopirido-[4,3-d]pirimidin-5-ona y su uso como inhibidores de wee-1.
EP3760638A3 (en) Compositions and methods utilizing lysophosphatidylcholine scaffolds
MY170630A (en) Freeze-dried formulations of fgf-18
MX2016004556A (es) Composicion de hueso comprimido y metodo para usar la misma.
EP2560633A4 (en) INTRAVENOUS COMPOSITIONS OF OMEGA-3 FATTY ACIDS AND METHOD OF USE
PH12017501070A1 (en) Peptides and their use in the treatment of skin
MY180844A (en) Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions
MX2019009952A (es) Formulaciones de evolocumab de baja viscosidad y alta concentracion y metodos de elaboracion de las mismas.
MX342119B (es) 2-oxi-quinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3.
WO2016149659A3 (en) Antisense-induced exon exclusion in myostatin
WO2015084883A3 (en) Compositions and methods for treating osteoarthritis
MX2015012720A (es) Sales basicas de adicion de nitroxolina y usos de las mismas.
WO2015081319A3 (en) Activity enhancing curcumin compositions and methods of use
PH12017500203A1 (en) Nutritional composition for use in promoting gut and/or liver maturation and/or repair
MX2016008441A (es) Formulacion de factor de crecimiento de fibroblastos 18 en geles de xiloglucano.

Legal Events

Date Code Title Description
FG Grant or registration