MX365899B - Composición farmacéutica que comprende un fragmento de péptido de hmgb1 para usarse en tratamiento de daño a la medula espinal. - Google Patents
Composición farmacéutica que comprende un fragmento de péptido de hmgb1 para usarse en tratamiento de daño a la medula espinal.Info
- Publication number
- MX365899B MX365899B MX2015005253A MX2015005253A MX365899B MX 365899 B MX365899 B MX 365899B MX 2015005253 A MX2015005253 A MX 2015005253A MX 2015005253 A MX2015005253 A MX 2015005253A MX 365899 B MX365899 B MX 365899B
- Authority
- MX
- Mexico
- Prior art keywords
- spinal cord
- cord injury
- novel method
- treating spinal
- hmgb1 fragment
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 2
- 208000020431 spinal cord injury Diseases 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000055207 HMGB1 Human genes 0.000 abstract 1
- 108700010013 HMGB1 Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a una composición farmacéutica para usarse en el tratamiento de daño a la médula espinal, en donde la composición farmacéutica comprende un fragmento de péptido de HMGB1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012235786 | 2012-10-25 | ||
PCT/JP2013/078759 WO2014065348A1 (ja) | 2012-10-25 | 2013-10-24 | Hmgb1断片を利用した脊髄の損傷に対する新規治療法 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015005253A MX2015005253A (es) | 2015-10-29 |
MX365899B true MX365899B (es) | 2019-06-19 |
Family
ID=50544721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015005253A MX365899B (es) | 2012-10-25 | 2013-10-24 | Composición farmacéutica que comprende un fragmento de péptido de hmgb1 para usarse en tratamiento de daño a la medula espinal. |
Country Status (18)
Country | Link |
---|---|
US (1) | US9688733B2 (es) |
EP (1) | EP2913059B1 (es) |
JP (1) | JP6253590B2 (es) |
KR (1) | KR102146822B1 (es) |
CN (1) | CN104955470B (es) |
AU (1) | AU2013335685B2 (es) |
BR (1) | BR112015008745B1 (es) |
CA (1) | CA2889299C (es) |
DK (1) | DK2913059T3 (es) |
ES (1) | ES2673861T3 (es) |
HK (2) | HK1212888A1 (es) |
MX (1) | MX365899B (es) |
PL (1) | PL2913059T3 (es) |
RU (1) | RU2649069C2 (es) |
SG (1) | SG11201503215XA (es) |
TR (1) | TR201807769T4 (es) |
WO (1) | WO2014065348A1 (es) |
ZA (1) | ZA201502829B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0911513A2 (pt) | 2008-04-30 | 2016-07-12 | Genomix Co Ltd | métodos e agentes para coleta de células tronco da medula óssea funcionais in vivo com alta eficiência |
DK3358011T3 (da) | 2011-04-26 | 2020-05-11 | Univ Osaka | Peptid til inducering af regenerering af væv og anvendelse deraf |
KR102146815B1 (ko) | 2012-10-25 | 2020-08-21 | 가부시키가이샤 스템림 | Hmgb1 단편을 이용한 신규 심근경색의 치료법 |
TWI805565B (zh) | 2017-01-27 | 2023-06-21 | 日商斯德武利姆股份有限公司 | 心肌病、陳舊性心肌梗塞及慢性心臟衰竭的治療藥物 |
CN111542335A (zh) | 2017-12-01 | 2020-08-14 | 斯特姆里姆有限公司 | 炎症性肠病的治疗药 |
EP3750553A4 (en) | 2018-02-08 | 2022-01-12 | Stemrim Inc. | THERAPEUTIC FOR PSORIASIS |
JP7405345B2 (ja) * | 2018-10-05 | 2023-12-26 | 株式会社ステムリム | 間葉系幹細胞の動員活性を有するペプチド |
MX2021004758A (es) | 2018-10-25 | 2021-08-24 | Univ Osaka | Agente terapeutico para el trastorno de cartilago. |
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JPS5238680B2 (es) | 1972-12-27 | 1977-09-30 | ||
US5658894A (en) | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
US5661127A (en) | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
JP3018313B2 (ja) | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
US6720340B1 (en) | 1999-07-28 | 2004-04-13 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine receptor agonists in stem cell and progenitor cell recruitment |
EP1114862A3 (de) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
WO2001062895A2 (en) | 2000-02-24 | 2001-08-30 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
JP3421741B2 (ja) | 2000-05-18 | 2003-06-30 | 筑波大学長 | 人工骨髄、血球細胞の増殖方法 |
ITMI20010562A1 (it) | 2001-03-16 | 2002-09-16 | Marco E Bianchi | Inibitori o antagonisti della proteina hmg1 per il trattamento di disordini vascolari |
DE10121254A1 (de) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
AU2002304710A1 (en) | 2001-04-30 | 2002-11-11 | Switch Biotech Ag | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
US7304034B2 (en) * | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
BR0209689A (pt) | 2001-05-15 | 2006-02-07 | Long Island Jewish Res Inst | Uso de fragmento de hmg como agente anti-inflamatório |
US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
ITMI20011986A1 (it) | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
EP1459759A4 (en) | 2001-11-19 | 2007-08-29 | Kyowa Hakko Kogyo Kk | MEDICAMENT FOR THE MOBILIZATION OF PLURIPOTENTIAL STEM CELLS FROM TISSUE IN THE PERIPHERAL BLOOD |
EP2305276A3 (en) | 2001-12-07 | 2011-09-21 | Cytori Therapeutics, Inc. | Processed lipoaspirate cells for use in therapy |
KR20050054907A (ko) | 2002-07-03 | 2005-06-10 | 폰다지오네 센트로 산 라파엘 델 몬테 테이보 | 조직 손상의 치료 및/또는 조직 회복의 촉진에서hmgb1 단백질의 용도 |
ATE427758T1 (de) | 2002-07-05 | 2009-04-15 | Univ Laval | Inhibitor des chemotaktischen faktors zur hemmung der entzundungsreaktionen |
GB0226251D0 (en) | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
NZ540067A (en) * | 2002-11-20 | 2007-05-31 | Critical Therapeutics Inc | A purified preparation of antibodies that specifically bind to a high mobility group box protein (HMGB) B box but do not specifically to non-B box epitopes of HMGB |
US20070154529A1 (en) | 2003-01-03 | 2007-07-05 | Alcedo Biotech Gmbh | Uses of dna binding proteins |
WO2004075855A2 (en) | 2003-02-26 | 2004-09-10 | Biomed Solutions, Llc | Process for in vivo treatment of specific biological targets in bodily fluid |
ATE411038T1 (de) | 2003-03-28 | 2008-10-15 | Univ Laval | S100 protein als aktivator neutrophiler zellen zur verminderung der neutropenie bei der krebsbehandlung |
US20050014255A1 (en) | 2003-05-29 | 2005-01-20 | Board Of Regents, The University Of Texas System | Stem cells for clinical and commercial uses |
WO2005025604A2 (en) | 2003-09-10 | 2005-03-24 | The General Hospital Corporation | Use of hmgb and hmgb fragments to decrease specific immune response |
ITRM20040058A1 (it) | 2004-02-03 | 2004-05-03 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali. |
AU2005264185A1 (en) | 2004-07-20 | 2006-01-26 | Centro Cardiologico Monzino S.P.A. - Irccs | Use of HMGB1 for wound healing |
MX2007001155A (es) | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
MX2007002557A (es) | 2004-09-03 | 2007-10-10 | Creabilis Therapeutics Spa | Uso de polipeptidos obtenidos a traves de mutaciones sistematicas de aminoacidos unicos de bloque-a humano y no humano de hmgb1 para prevenir y/o antagonizar las patologias inducidas por hmgb1. |
KR100593397B1 (ko) | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
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WO2006114805A2 (en) | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb2 and hmgb3 proteins for medical applications |
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WO2007130725A2 (en) | 2006-02-06 | 2007-11-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of hmgb1 for protection against ischemia reperfusion injury |
JP4982739B2 (ja) | 2006-06-01 | 2012-07-25 | 国立大学法人 東京医科歯科大学 | ポリグルタミン病の予防・治療剤 |
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BRPI0911513A2 (pt) | 2008-04-30 | 2016-07-12 | Genomix Co Ltd | métodos e agentes para coleta de células tronco da medula óssea funcionais in vivo com alta eficiência |
KR101728379B1 (ko) * | 2008-04-30 | 2017-04-19 | 가부시키가이샤 제노믹스 | 말초 순환으로의 골수 유래 다능성 줄기세포 동원약 |
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WO2011046570A1 (en) * | 2009-10-16 | 2011-04-21 | The University Of Medicine And Dentistry Of New Jersey | Method for treating chronic nerve tissue injury using a cell therapy strategy |
CA2778759A1 (en) | 2009-10-28 | 2011-05-05 | Genomix Co., Ltd. | Tissue-regeneration promoter using recruitment of bone marrow mesenchymal stem cells and/or pluripotent stem cells in blood |
DK3358011T3 (da) | 2011-04-26 | 2020-05-11 | Univ Osaka | Peptid til inducering af regenerering af væv og anvendelse deraf |
CN102443064A (zh) | 2011-11-03 | 2012-05-09 | 刘誉 | 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用 |
KR102146815B1 (ko) | 2012-10-25 | 2020-08-21 | 가부시키가이샤 스템림 | Hmgb1 단편을 이용한 신규 심근경색의 치료법 |
-
2013
- 2013-10-24 MX MX2015005253A patent/MX365899B/es active IP Right Grant
- 2013-10-24 EP EP13849823.3A patent/EP2913059B1/en active Active
- 2013-10-24 US US14/436,920 patent/US9688733B2/en active Active
- 2013-10-24 AU AU2013335685A patent/AU2013335685B2/en active Active
- 2013-10-24 CN CN201380067951.4A patent/CN104955470B/zh active Active
- 2013-10-24 DK DK13849823.3T patent/DK2913059T3/en active
- 2013-10-24 ES ES13849823.3T patent/ES2673861T3/es active Active
- 2013-10-24 RU RU2015119523A patent/RU2649069C2/ru active
- 2013-10-24 PL PL13849823T patent/PL2913059T3/pl unknown
- 2013-10-24 CA CA2889299A patent/CA2889299C/en active Active
- 2013-10-24 SG SG11201503215XA patent/SG11201503215XA/en unknown
- 2013-10-24 JP JP2014543335A patent/JP6253590B2/ja active Active
- 2013-10-24 WO PCT/JP2013/078759 patent/WO2014065348A1/ja active Application Filing
- 2013-10-24 BR BR112015008745-0A patent/BR112015008745B1/pt active IP Right Grant
- 2013-10-24 TR TR2018/07769T patent/TR201807769T4/tr unknown
- 2013-10-24 KR KR1020157013591A patent/KR102146822B1/ko active IP Right Grant
-
2015
- 2015-04-24 ZA ZA2015/02829A patent/ZA201502829B/en unknown
-
2016
- 2016-01-25 HK HK16100783.3A patent/HK1212888A1/zh unknown
- 2016-02-04 HK HK16101298.9A patent/HK1213201A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
ZA201502829B (en) | 2020-11-25 |
SG11201503215XA (en) | 2015-06-29 |
WO2014065348A1 (ja) | 2014-05-01 |
ES2673861T3 (es) | 2018-06-26 |
CA2889299C (en) | 2023-02-14 |
MX2015005253A (es) | 2015-10-29 |
RU2649069C2 (ru) | 2018-04-02 |
KR102146822B1 (ko) | 2020-08-21 |
HK1213201A1 (zh) | 2016-06-30 |
PL2913059T3 (pl) | 2018-09-28 |
BR112015008745A2 (pt) | 2017-11-21 |
JP6253590B2 (ja) | 2017-12-27 |
RU2015119523A (ru) | 2016-12-20 |
US20150274792A1 (en) | 2015-10-01 |
CN104955470A (zh) | 2015-09-30 |
BR112015008745B1 (pt) | 2022-08-02 |
AU2013335685A1 (en) | 2015-05-14 |
JPWO2014065348A1 (ja) | 2016-09-08 |
EP2913059A4 (en) | 2016-03-30 |
KR20150102957A (ko) | 2015-09-09 |
AU2013335685B2 (en) | 2017-10-12 |
DK2913059T3 (en) | 2018-06-25 |
CA2889299A1 (en) | 2014-05-01 |
CN104955470B (zh) | 2017-06-16 |
EP2913059A1 (en) | 2015-09-02 |
HK1212888A1 (zh) | 2016-06-24 |
US9688733B2 (en) | 2017-06-27 |
EP2913059B1 (en) | 2018-04-11 |
TR201807769T4 (tr) | 2018-06-21 |
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Legal Events
Date | Code | Title | Description |
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HC | Change of company name or juridical status |
Owner name: KUMIAI CHEMICAL INDUSTRY CO., LTD. |
|
FG | Grant or registration |