MX349705B - Bifidobacterium longum. - Google Patents
Bifidobacterium longum.Info
- Publication number
- MX349705B MX349705B MX2016005357A MX2016005357A MX349705B MX 349705 B MX349705 B MX 349705B MX 2016005357 A MX2016005357 A MX 2016005357A MX 2016005357 A MX2016005357 A MX 2016005357A MX 349705 B MX349705 B MX 349705B
- Authority
- MX
- Mexico
- Prior art keywords
- bifidobacterium longum
- genome
- multiple embodiments
- various novel
- embodiments described
- Prior art date
Links
- 241001608472 Bifidobacterium longum Species 0.000 title abstract 3
- 229940009291 bifidobacterium longum Drugs 0.000 title abstract 2
- 239000006041 probiotic Substances 0.000 abstract 1
- 230000000529 probiotic effect Effects 0.000 abstract 1
- 235000018291 probiotics Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0323—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin using only lactic acid bacteria, e.g. Pediococcus and Leuconostoc species; Bifidobacteria; Microbial starters in general
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
- A23C19/061—Addition of, or treatment with, microorganisms
- A23C19/062—Addition of, or treatment with, microorganisms using only lactic acid bacteria, e.g. pediococcus, leconostoc or bifidus sp., or propionic acid bacteria; Treatment with non-specified acidifying bacterial cultures
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
- A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
- A23L2/382—Other non-alcoholic beverages fermented
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/533—Longum
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Nutrition Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Dairy Products (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a las múltiples modalidades descritas en la presente comprenden el genoma de una cepa de probiótico Bifidobacterium Iongum y los genes codificados por el genoma. Se describen diversas variedades de Bifidobacterium Iongum nuevas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11351308P | 2008-11-11 | 2008-11-11 | |
US14998009P | 2009-02-04 | 2009-02-04 | |
PCT/IE2009/000079 WO2010055499A2 (en) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum |
Publications (1)
Publication Number | Publication Date |
---|---|
MX349705B true MX349705B (es) | 2017-08-09 |
Family
ID=41572466
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016005357A MX349705B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
MX2011005006A MX339907B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
MX2016005356A MX349706B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
MX2016005358A MX356598B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011005006A MX339907B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
MX2016005356A MX349706B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
MX2016005358A MX356598B (es) | 2008-11-11 | 2009-11-11 | Bifidobacterium longum. |
Country Status (11)
Country | Link |
---|---|
US (3) | US9771624B2 (es) |
EP (1) | EP2352389B1 (es) |
CN (1) | CN102984955B (es) |
AU (1) | AU2009315298A1 (es) |
BR (1) | BRPI0921758A2 (es) |
CA (3) | CA2852487C (es) |
ES (1) | ES2566496T3 (es) |
MX (4) | MX349705B (es) |
PL (1) | PL2352389T3 (es) |
RU (1) | RU2570557C2 (es) |
WO (1) | WO2010055499A2 (es) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2134835B1 (en) * | 2007-03-28 | 2014-10-15 | Alimentary Health Limited | Probiotic bifidobacterium strains |
MX349705B (es) | 2008-11-11 | 2017-08-09 | Alimentary Health Ltd | Bifidobacterium longum. |
EP2283810A1 (en) * | 2009-07-16 | 2011-02-16 | University College Cork-National University of Ireland, Cork | Orally administered bacteria as vehicles for systemic delivery of agents |
RU2546251C2 (ru) | 2009-11-11 | 2015-04-10 | Алиментари Хелс Лимитед | Пробиотический штамм бифидобактерий |
AU2010317423C1 (en) * | 2009-11-11 | 2015-01-22 | Alimentary Health Limited | A bifidobacterium strain |
US9259019B2 (en) | 2010-11-11 | 2016-02-16 | Mars, Incorporated | Bifidobacteriumstrain |
US11951139B2 (en) | 2015-11-30 | 2024-04-09 | Seed Health, Inc. | Method and system for reducing the likelihood of osteoporosis |
US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
US11844720B2 (en) | 2011-02-04 | 2023-12-19 | Seed Health, Inc. | Method and system to reduce the likelihood of dental caries and halitosis |
US11951140B2 (en) | 2011-02-04 | 2024-04-09 | Seed Health, Inc. | Modulation of an individual's gut microbiome to address osteoporosis and bone disease |
CN104780932A (zh) | 2012-02-29 | 2015-07-15 | 伊西康内外科公司 | 微生物区系的组合物及与其相关的方法 |
US9161957B2 (en) | 2012-08-03 | 2015-10-20 | Life Well Lived, Llc | Compositions and methods for reducing blood alcohol content |
EP2970208A4 (en) | 2013-03-15 | 2016-11-30 | Gen Hospital Corp | SPECIFICITY INCREASES FOR RNA-MEDIATED CHANGES |
US10760064B2 (en) | 2013-03-15 | 2020-09-01 | The General Hospital Corporation | RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci |
US10011850B2 (en) | 2013-06-21 | 2018-07-03 | The General Hospital Corporation | Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing |
DK3066201T3 (en) | 2013-11-07 | 2018-06-06 | Editas Medicine Inc | CRISPR-RELATED PROCEDURES AND COMPOSITIONS WITH LEADING GRADES |
WO2015074054A1 (en) * | 2013-11-18 | 2015-05-21 | The Trustees Of Columbia University In The City Of New York | Improving microbial fitness in the mammalian gut |
US11969445B2 (en) | 2013-12-20 | 2024-04-30 | Seed Health, Inc. | Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH |
US11998574B2 (en) | 2013-12-20 | 2024-06-04 | Seed Health, Inc. | Method and system for modulating an individual's skin microbiome |
US11833177B2 (en) | 2013-12-20 | 2023-12-05 | Seed Health, Inc. | Probiotic to enhance an individual's skin microbiome |
US11826388B2 (en) | 2013-12-20 | 2023-11-28 | Seed Health, Inc. | Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation |
US11980643B2 (en) | 2013-12-20 | 2024-05-14 | Seed Health, Inc. | Method and system to modify an individual's gut-brain axis to provide neurocognitive protection |
US11839632B2 (en) | 2013-12-20 | 2023-12-12 | Seed Health, Inc. | Topical application of CRISPR-modified bacteria to treat acne vulgaris |
US12005085B2 (en) | 2013-12-20 | 2024-06-11 | Seed Health, Inc. | Probiotic method and composition for maintaining a healthy vaginal microbiome |
CN114376234A (zh) | 2014-10-24 | 2022-04-22 | 进化生物系统股份有限公司 | 活化的双歧杆菌及其应用方法 |
CA2964480A1 (en) | 2014-10-31 | 2016-05-06 | Whole Biome Inc. | Methods and compositions relating to microbial treatment and diagnosis of disorders |
WO2016176380A1 (en) | 2015-04-28 | 2016-11-03 | The Procter & Gamble Company | Compositions comprising whole, non-viable micrococcus for improving skin health |
CN104894005B (zh) * | 2015-04-30 | 2018-05-22 | 江苏紫石微康生物科技有限公司 | 一种高产胞外多糖的乳酸菌bl21及制备方法和应用 |
RU2614116C2 (ru) * | 2015-07-21 | 2017-03-22 | Головин Михаил Анатольевич | Способ получения пробиотической композиции |
US20180280453A1 (en) * | 2015-08-27 | 2018-10-04 | Alimentary Health Limited | Use of bifidobacterium longum and an exopolysaccharide produced thereby |
CN108135946A (zh) * | 2015-08-27 | 2018-06-08 | 宝洁公司 | 长双歧杆菌 |
US9926546B2 (en) | 2015-08-28 | 2018-03-27 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
US9512446B1 (en) | 2015-08-28 | 2016-12-06 | The General Hospital Corporation | Engineered CRISPR-Cas9 nucleases |
US10973862B2 (en) | 2015-12-11 | 2021-04-13 | Precisionbiotics Group Limited | Bifidobacterium longum for treating obesity and associated metabolic disorders |
CN105907682A (zh) * | 2016-05-31 | 2016-08-31 | 深圳先进技术研究院 | 一种产高粘性多糖的细菌的筛选方法 |
AU2018326705A1 (en) | 2017-08-30 | 2020-03-05 | Pendulum Therapeutics, Inc. | Methods and compositions for treatment of microbiome-associated disorders |
US20200289588A1 (en) * | 2018-01-29 | 2020-09-17 | Precisionbiotics Group Limited | Bifidobacterium longum ncimb 41676 |
EP4147704A1 (en) * | 2018-01-29 | 2023-03-15 | PrecisionBiotics Group Limited | Bifidobacterium longum ncimb 41676 |
WO2019145573A1 (en) | 2018-01-29 | 2019-08-01 | Alimentary Health Limited | Bifidobacterium longum ncimb 41676 |
WO2019145570A1 (en) | 2018-01-29 | 2019-08-01 | Alimentary Health Limited | A combination product for prophylaxis and treatment of irritable bowel syndrome |
EP3745871A1 (en) * | 2018-01-29 | 2020-12-09 | PrecisionBiotics Group Limited | Bifidobacterium longum ncimb 41676 |
JP2022529054A (ja) | 2019-04-17 | 2022-06-16 | ニューテック・ベンチャーズ | 持続性が強化された新規微生物を含む組成物、新規微生物とプレバイオティクスの相乗的組み合わせ、およびそのような微生物の分離方法 |
CN110205393B (zh) * | 2019-07-03 | 2020-07-24 | 南京先声医学检验有限公司 | 用于检测营养代谢能力相关snp位点的引物组、应用、产品及方法 |
JP7013419B2 (ja) * | 2019-08-07 | 2022-02-15 | 日清食品ホールディングス株式会社 | 炎症性サイトカインの産生誘導活性は低いが抗炎症性サイトカインの産生誘導活性が高いビフィズス菌 |
WO2021077543A1 (zh) * | 2019-10-23 | 2021-04-29 | 江南大学 | 一种亚油酸异构酶及其在共轭亚油酸生产中的应用 |
CN112391484B (zh) * | 2020-11-17 | 2022-12-27 | 江南大学 | 一种定量检测长双歧杆菌菌株的方法 |
WO2023137381A2 (en) * | 2022-01-12 | 2023-07-20 | Washington University | Bifidobacterium infantis formulations |
CN114507649B (zh) * | 2022-02-16 | 2023-11-21 | 吉林大学 | 嗜热酶及一锅法高效合成udp-葡萄糖和udp-葡萄糖醛酸的方法 |
CN114774335B (zh) * | 2022-06-22 | 2022-09-02 | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 具有靶向葡萄糖激酶显著降血糖和降血脂功效的长双歧杆菌070103及其应用 |
CN117568301B (zh) * | 2023-11-16 | 2024-05-10 | 安徽农业大学 | 一种通过糖多孢红霉菌sace_1646基因提高红霉素产量的方法 |
CN118086539B (zh) * | 2024-03-05 | 2024-10-01 | 中国食品发酵工业研究院有限公司 | 长双歧杆菌婴儿亚种的PMA-qPCR活菌定量检测方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010049115A1 (en) | 2000-01-17 | 2001-12-06 | Collins John Kevin | Vitro model for gastrointestinal inflammation |
ID29150A (id) * | 1999-01-15 | 2001-08-02 | Entpr Ireland Cs | Penggunaan lactobacillus salivarius |
EP1227152A1 (en) * | 2001-01-30 | 2002-07-31 | Société des Produits Nestlé S.A. | Bacterial strain and genome of bifidobacterium |
MY148872A (en) * | 2006-02-15 | 2013-06-14 | Nestec Sa | Use of bifidobacterium longum for the prevention and treatment of inflammation |
RU2333655C2 (ru) * | 2006-07-26 | 2008-09-20 | Государственное образовательное учреждение высшего профессионального образования Восточно-Сибирский государственный технологический университет | Способ получения селенсодержащей биологически активной добавки |
WO2010003916A1 (en) * | 2008-07-11 | 2010-01-14 | Chr. Hansen A/S | New probiotic bifidobacterium longum |
MX349705B (es) | 2008-11-11 | 2017-08-09 | Alimentary Health Ltd | Bifidobacterium longum. |
-
2009
- 2009-11-11 MX MX2016005357A patent/MX349705B/es unknown
- 2009-11-11 MX MX2011005006A patent/MX339907B/es active IP Right Grant
- 2009-11-11 CA CA2852487A patent/CA2852487C/en active Active
- 2009-11-11 US US12/616,752 patent/US9771624B2/en active Active
- 2009-11-11 BR BRPI0921758A patent/BRPI0921758A2/pt not_active Application Discontinuation
- 2009-11-11 PL PL09753220T patent/PL2352389T3/pl unknown
- 2009-11-11 AU AU2009315298A patent/AU2009315298A1/en not_active Abandoned
- 2009-11-11 EP EP09753220.4A patent/EP2352389B1/en active Active
- 2009-11-11 CN CN200980145029.6A patent/CN102984955B/zh active Active
- 2009-11-11 MX MX2016005356A patent/MX349706B/es unknown
- 2009-11-11 CA CA2741942A patent/CA2741942C/en active Active
- 2009-11-11 ES ES09753220.4T patent/ES2566496T3/es active Active
- 2009-11-11 RU RU2011120271/10A patent/RU2570557C2/ru active
- 2009-11-11 WO PCT/IE2009/000079 patent/WO2010055499A2/en active Application Filing
- 2009-11-11 CA CA2852479A patent/CA2852479C/en active Active
- 2009-11-11 MX MX2016005358A patent/MX356598B/es unknown
-
2017
- 2017-08-23 US US15/683,805 patent/US10689719B2/en active Active
-
2020
- 2020-05-12 US US16/872,610 patent/US20200377961A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2852487C (en) | 2017-01-31 |
ES2566496T3 (es) | 2016-04-13 |
US20200377961A1 (en) | 2020-12-03 |
MX349706B (es) | 2017-08-09 |
CA2741942A1 (en) | 2010-05-20 |
US20100183559A1 (en) | 2010-07-22 |
EP2352389A2 (en) | 2011-08-10 |
CA2852479C (en) | 2017-01-24 |
EP2352389B1 (en) | 2016-01-06 |
BRPI0921758A2 (pt) | 2019-07-30 |
US9771624B2 (en) | 2017-09-26 |
CA2852487A1 (en) | 2010-05-20 |
US20180016647A1 (en) | 2018-01-18 |
CA2741942C (en) | 2018-01-16 |
RU2570557C2 (ru) | 2015-12-10 |
WO2010055499A3 (en) | 2010-09-23 |
MX356598B (es) | 2018-06-04 |
WO2010055499A2 (en) | 2010-05-20 |
PL2352389T3 (pl) | 2016-07-29 |
CN102984955A (zh) | 2013-03-20 |
US10689719B2 (en) | 2020-06-23 |
RU2011120271A (ru) | 2012-12-20 |
CN102984955B (zh) | 2015-01-07 |
CA2852479A1 (en) | 2010-05-20 |
MX2011005006A (es) | 2011-05-24 |
AU2009315298A1 (en) | 2010-05-20 |
MX339907B (es) | 2016-06-14 |
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