MX349321B - Terapia combinada. - Google Patents
Terapia combinada.Info
- Publication number
- MX349321B MX349321B MX2014000199A MX2014000199A MX349321B MX 349321 B MX349321 B MX 349321B MX 2014000199 A MX2014000199 A MX 2014000199A MX 2014000199 A MX2014000199 A MX 2014000199A MX 349321 B MX349321 B MX 349321B
- Authority
- MX
- Mexico
- Prior art keywords
- combination therapy
- individuals
- cancer
- minimising
- progression
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 102100037602 P2X purinoceptor 7 Human genes 0.000 abstract 1
- 101710189965 P2X purinoceptor 7 Proteins 0.000 abstract 1
- 230000008348 humoral response Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a un receptor P2X7 o un fragmento del mismo para usarse en un método para minimizar la progresión del cáncer en un individuo, en donde el individuo ha recibido un sitio no propio de unión de antígenos para el tratamiento del cáncer, en donde el fragmento de un receptor P2X7 es capaz de formar una respuesta inmunitaria a un receptor P2X7, y que incluye una secuencia de aminoácidos seleccionada del grupo que consiste en SEQ ID NO: 2, 3 y 4.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2011902623A AU2011902623A0 (en) | 2011-07-01 | Combination therapy | |
PCT/AU2012/000795 WO2013003895A1 (en) | 2011-07-01 | 2012-07-02 | Combination therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014000199A MX2014000199A (es) | 2014-06-11 |
MX349321B true MX349321B (es) | 2017-07-21 |
Family
ID=47436374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014000199A MX349321B (es) | 2011-07-01 | 2012-07-02 | Terapia combinada. |
Country Status (11)
Country | Link |
---|---|
US (3) | US9566318B2 (es) |
EP (1) | EP2726095B1 (es) |
JP (2) | JP6305920B2 (es) |
CN (1) | CN103702683B (es) |
AU (1) | AU2012278921B2 (es) |
BR (1) | BR112013033974A2 (es) |
CA (1) | CA2840251C (es) |
ES (1) | ES2689272T3 (es) |
MX (1) | MX349321B (es) |
WO (1) | WO2013003895A1 (es) |
ZA (1) | ZA201400120B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4384852B2 (ja) | 2001-01-17 | 2009-12-16 | イントリート ピーティーワイ リミテッド | 非機能性p2x7レセプター抗体、癌及びその他の容態の診断及び処置 |
US8440186B2 (en) | 2007-09-14 | 2013-05-14 | Biosceptre International Limited | P2X7 epitopes |
BRPI0915367B8 (pt) | 2008-07-04 | 2021-05-25 | Biosceptre International Ltd | peptídeo anti-p2x7 |
EP3395832B1 (en) | 2009-08-20 | 2021-11-24 | Biosceptre (Aust) Pty Ltd | Anti p2x7 receptor antibodies and fragments thereof |
EP3321285B1 (en) | 2009-12-24 | 2019-04-24 | Biosceptre (Aust) Pty Ltd | Antibodies to non-functional oligomeric p2x7 receptors |
US9562094B2 (en) | 2010-09-10 | 2017-02-07 | Biosceptre (Aust) Pty Ltd | Companion animal treatments |
WO2012090124A2 (en) | 2010-12-29 | 2012-07-05 | Ecolab Usa Inc. | IN SITU GENERATION OF PEROXYCARBOXYLIC ACIDS AT ALKALINE pH, AND METHODS OF USE THEREOF |
WO2012090125A2 (en) | 2010-12-29 | 2012-07-05 | Ecolab Usa Inc. | Sugar ester peracid on-site generator and formulator |
MX349321B (es) | 2011-07-01 | 2017-07-21 | Biosceptre (Aust) Pty Ltd | Terapia combinada. |
US9321664B2 (en) | 2011-12-20 | 2016-04-26 | Ecolab Usa Inc. | Stable percarboxylic acid compositions and uses thereof |
BR122018076176B1 (pt) | 2014-12-18 | 2021-06-01 | Ecolab Usa Inc | Método para formar ácido peroxifórmico, método para tratar uma superfície, método para tratar um biofilme em uma superfície e método para desinfetar uma superfície da pele |
AU2015364492B2 (en) | 2014-12-18 | 2018-08-09 | Ecolab Usa Inc. | Methods for forming peroxyformic acid and uses thereof |
US11040902B2 (en) | 2014-12-18 | 2021-06-22 | Ecolab Usa Inc. | Use of percarboxylic acids for scale prevention in treatment systems |
EP3816294A1 (en) | 2015-09-11 | 2021-05-05 | Biosceptre (UK) Limited | Chimeric antigen receptors and uses thereof |
MX2019004410A (es) | 2016-10-21 | 2019-09-26 | Biosceptre Uk Ltd | Particulas citotoxicas. |
US12058999B2 (en) | 2018-08-22 | 2024-08-13 | Ecolab Usa Inc. | Hydrogen peroxide and peracid stabilization with molecules based on a pyridine carboxylic acid |
MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
WO2021019222A1 (en) * | 2019-07-26 | 2021-02-04 | Biosceptre (Uk) Limited | P2x7 receptor targeted therapy |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE920765A1 (en) | 1991-03-12 | 1992-09-23 | Scripps Research Inst | Cell surface receptors homologous to coagulation factors v¹and viii |
US5500161A (en) | 1993-09-21 | 1996-03-19 | Massachusetts Institute Of Technology And Virus Research Institute | Method for making hydrophobic polymeric microparticles |
US5985603A (en) | 1994-05-27 | 1999-11-16 | Glaxo Group Limited | P2x receptor DNA and protein sequence |
US5981218A (en) | 1995-08-09 | 1999-11-09 | Bristol-Myers Squibb Company | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides |
WO1997041222A1 (en) | 1996-04-30 | 1997-11-06 | Smithkline Beecham P.L.C. | HUMAN P2x4 RECEPTOR SPLICE-VARIANTS |
US6303338B1 (en) | 1996-08-16 | 2001-10-16 | Human Genome Sciences, Inc. | Pancreas-derived plasminogen activator inhibitor |
US6306393B1 (en) | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
JP3885177B2 (ja) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | ヒト遺伝子 |
US6133434A (en) | 1997-04-28 | 2000-10-17 | Glaxo Group Limited | Purinergic receptor |
ES2329851T3 (es) | 1998-06-01 | 2009-12-01 | Agensys, Inc. | Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos. |
DE19829473C2 (de) | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Verfahren zur frühen Diagnose von Carcinomen |
EP1157038A4 (en) | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
AUPP991199A0 (en) | 1999-04-21 | 1999-05-13 | University Of Sydney, The | Methods for diagnosing pre-cancerous and cancerous conditions |
NL1012452C2 (nl) | 1999-06-28 | 2001-01-02 | Univ Delft Tech | Werkwijze voor de bereiding van eiwit-agglomeraten, eiwit-agglomeraten, een levensmiddel en een farmaceutisch preparaat die deze bevatten alsmede een inrichting voor het bereiden van eiwit-agglomeraten. |
AU1339701A (en) | 1999-10-22 | 2001-05-08 | Lifespan Biosciences, Inc. | Anti-cancer nucleic acid and protein targets |
AUPR201500A0 (en) | 2000-12-11 | 2001-01-11 | Biosceptre Pty Ltd | Methods for identifying pre-neoplastic and neoplastic states in mammals |
JP4384852B2 (ja) | 2001-01-17 | 2009-12-16 | イントリート ピーティーワイ リミテッド | 非機能性p2x7レセプター抗体、癌及びその他の容態の診断及び処置 |
JP4467973B2 (ja) * | 2001-09-03 | 2010-05-26 | イントリート ピーティーワイ リミテッド | 非機能性p2x7リセプターに対応する抗体、癌及びその他の症状の診断及び治療 |
DK1473367T3 (da) | 2003-04-17 | 2007-10-01 | Affectis Pharmaceuticals Ag | Midler og fremgangsmåder til diagnosticering og behandling af effektive lidelser |
SI2163260T1 (sl) * | 2004-01-23 | 2017-07-31 | Msd Italia S.R.L. | Nosilci šimpanzjih adenovirusnih cepiv |
US7858323B2 (en) | 2004-06-09 | 2010-12-28 | The Regents Of The University Of Michigan | Phage microarray profiling of the humoral response to disease |
GB0419295D0 (en) * | 2004-08-31 | 2004-09-29 | Genomica Sau | Methods and compositions to prevent neuronal degeneration |
US20090215727A1 (en) | 2005-05-05 | 2009-08-27 | Medicure International Inc. | Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphate and vitamin b6 related compounds |
US7767789B2 (en) | 2005-06-02 | 2010-08-03 | University Hopitals of Cleveland | Truncated proteins as cancer markers |
WO2007027957A2 (en) | 2005-08-31 | 2007-03-08 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
WO2008043146A1 (en) | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Antibodies against non functional p2x7 receptor |
JP2010505426A (ja) | 2006-10-10 | 2010-02-25 | バイオスセプター インターナショナル リミテッド | 非機能性p2x7受容体に対する抗体を産生するハイブリドーマ |
US8440186B2 (en) | 2007-09-14 | 2013-05-14 | Biosceptre International Limited | P2X7 epitopes |
EP2201377B1 (en) | 2007-09-14 | 2012-01-18 | Biosceptre International Limited | Purinergic (p2x) receptors in extra-cellular body fluid |
BRPI0915367B8 (pt) | 2008-07-04 | 2021-05-25 | Biosceptre International Ltd | peptídeo anti-p2x7 |
KR20170097234A (ko) * | 2008-12-10 | 2017-08-25 | 더 헨리 엠. 잭슨 파운데이션 포 더 어드벤스먼트 오브 밀리터리 메디신, 인코포레이티드 | 유방암 재발 예방용 백신 |
EP3395832B1 (en) | 2009-08-20 | 2021-11-24 | Biosceptre (Aust) Pty Ltd | Anti p2x7 receptor antibodies and fragments thereof |
EP3321285B1 (en) * | 2009-12-24 | 2019-04-24 | Biosceptre (Aust) Pty Ltd | Antibodies to non-functional oligomeric p2x7 receptors |
WO2011131472A1 (en) | 2010-04-22 | 2011-10-27 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
US9562094B2 (en) | 2010-09-10 | 2017-02-07 | Biosceptre (Aust) Pty Ltd | Companion animal treatments |
MX349321B (es) | 2011-07-01 | 2017-07-21 | Biosceptre (Aust) Pty Ltd | Terapia combinada. |
-
2012
- 2012-07-02 MX MX2014000199A patent/MX349321B/es active IP Right Grant
- 2012-07-02 EP EP12807960.5A patent/EP2726095B1/en active Active
- 2012-07-02 AU AU2012278921A patent/AU2012278921B2/en active Active
- 2012-07-02 CA CA2840251A patent/CA2840251C/en active Active
- 2012-07-02 BR BR112013033974A patent/BR112013033974A2/pt not_active Application Discontinuation
- 2012-07-02 JP JP2014517338A patent/JP6305920B2/ja active Active
- 2012-07-02 CN CN201280033124.9A patent/CN103702683B/zh active Active
- 2012-07-02 WO PCT/AU2012/000795 patent/WO2013003895A1/en active Application Filing
- 2012-07-02 US US14/129,240 patent/US9566318B2/en active Active
- 2012-07-02 ES ES12807960.5T patent/ES2689272T3/es active Active
-
2014
- 2014-01-07 ZA ZA2014/00120A patent/ZA201400120B/en unknown
-
2017
- 2017-01-05 US US15/399,337 patent/US10245308B2/en active Active
-
2018
- 2018-03-06 JP JP2018039564A patent/JP6490270B2/ja active Active
-
2019
- 2019-02-05 US US16/268,344 patent/US10543262B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US9566318B2 (en) | 2017-02-14 |
ZA201400120B (en) | 2015-09-30 |
EP2726095A4 (en) | 2015-01-07 |
CN103702683A (zh) | 2014-04-02 |
US10543262B2 (en) | 2020-01-28 |
CA2840251C (en) | 2023-09-12 |
CA2840251A1 (en) | 2013-01-10 |
ES2689272T3 (es) | 2018-11-13 |
US20190224290A1 (en) | 2019-07-25 |
JP2018087249A (ja) | 2018-06-07 |
CN103702683B (zh) | 2017-07-04 |
WO2013003895A1 (en) | 2013-01-10 |
JP2014520759A (ja) | 2014-08-25 |
US20150004179A1 (en) | 2015-01-01 |
EP2726095A1 (en) | 2014-05-07 |
US20170157229A1 (en) | 2017-06-08 |
EP2726095B1 (en) | 2018-06-06 |
US10245308B2 (en) | 2019-04-02 |
MX2014000199A (es) | 2014-06-11 |
BR112013033974A2 (pt) | 2017-02-14 |
AU2012278921B2 (en) | 2016-11-10 |
JP6490270B2 (ja) | 2019-03-27 |
JP6305920B2 (ja) | 2018-04-04 |
AU2012278921A1 (en) | 2014-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |