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MX2022012824A - Metodos para enriquecer vesiculas extracelulares de muestras de liquido biologico. - Google Patents

Metodos para enriquecer vesiculas extracelulares de muestras de liquido biologico.

Info

Publication number
MX2022012824A
MX2022012824A MX2022012824A MX2022012824A MX2022012824A MX 2022012824 A MX2022012824 A MX 2022012824A MX 2022012824 A MX2022012824 A MX 2022012824A MX 2022012824 A MX2022012824 A MX 2022012824A MX 2022012824 A MX2022012824 A MX 2022012824A
Authority
MX
Mexico
Prior art keywords
biological fluid
fluid samples
extracellular vesicles
methods
enriching extracellular
Prior art date
Application number
MX2022012824A
Other languages
English (en)
Inventor
Christopher J Lowe
Vicki Plaks
Jane M Ruppel
Rebecca Suttmann
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2022012824A publication Critical patent/MX2022012824A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La invención proporciona métodos para enriquecer vesículas extracelulares (EV), que incluyen exosomas, de muestras de líquido biológico de sujetos y, opcionalmente, para realizar pruebas posteriores de las EV para identificar la presencia de biomarcadores específicos.
MX2022012824A 2020-04-17 2021-04-16 Metodos para enriquecer vesiculas extracelulares de muestras de liquido biologico. MX2022012824A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063011583P 2020-04-17 2020-04-17
PCT/US2021/027627 WO2021211935A1 (en) 2020-04-17 2021-04-16 Methods for enriching extracellular vesicles from biological fluid samples

Publications (1)

Publication Number Publication Date
MX2022012824A true MX2022012824A (es) 2022-11-07

Family

ID=75919381

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022012824A MX2022012824A (es) 2020-04-17 2021-04-16 Metodos para enriquecer vesiculas extracelulares de muestras de liquido biologico.

Country Status (13)

Country Link
US (1) US20230204588A1 (es)
EP (1) EP4136451A1 (es)
JP (1) JP2023522003A (es)
KR (1) KR20230004496A (es)
CN (1) CN115427810A (es)
AR (1) AR122422A1 (es)
AU (1) AU2021257455A1 (es)
BR (1) BR112022020884A2 (es)
CA (1) CA3178835A1 (es)
IL (1) IL297284A (es)
MX (1) MX2022012824A (es)
TW (1) TW202204896A (es)
WO (1) WO2021211935A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114073865B (zh) * 2022-01-17 2022-11-25 深圳市达科为生物工程有限公司 去除血清中外泌体的方法及过滤装置
WO2023196586A1 (en) * 2022-04-07 2023-10-12 The Regents Of The University Of Michigan Methods and devices for screening extracellular vesicles
WO2024206493A1 (en) * 2023-03-27 2024-10-03 The General Hospital Corporation Molecular analysis of extracellular vesicles (evs) for the detection of idiopathic pulmonary fibrosis
KR20240154736A (ko) * 2023-04-18 2024-10-28 가톨릭대학교 산학협력단 면역관문 억제제의 표적화된 전달을 위한 세포외소포체의 용도
KR20240159543A (ko) * 2023-04-28 2024-11-05 연세대학교 산학협력단 유방암 유래 엑소좀 또는 세포외 소포체 분리 방법
WO2024249948A1 (en) * 2023-05-31 2024-12-05 Mayo Foundation For Medical Education And Research Methods and materials for assessing and treating cancer
CN117153252B (zh) * 2023-08-31 2024-08-16 山东第一医科大学附属省立医院(山东省立医院) 一种用于弥漫大b细胞淋巴瘤患者预后生物标志物及其系统和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2827894A1 (en) * 2011-02-22 2012-08-30 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers
WO2013049636A1 (en) * 2011-09-30 2013-04-04 The Regents Of The University Of Michigan System for detecting rare cells
CN105723221B (zh) * 2013-11-06 2018-07-06 Jsr株式会社 分离方法、检测方法、信号测定方法、疾病的判定方法、疾病治疗药的药效评价方法、试剂盒以及液态组合物
US10874610B2 (en) * 2016-10-19 2020-12-29 Northwestern University Extracellular vesicle-based diagnostics and engineered exosomes for targeted therapeutics against cancer
IL270864B2 (en) * 2017-05-24 2025-01-01 Nanosomix Inc Identification of biomarkers on vesicles for diagnosis and prognosis of diseases and disorders
WO2019014486A1 (en) * 2017-07-12 2019-01-17 Exosome Diagnostics, Inc. METHODS FOR ISOLATING AND ENRICHING POPULATIONS OF EXTRACELLULAR VESICLES DERIVED FROM BIOFLUIDS, AND METHODS OF USE THEREOF

Also Published As

Publication number Publication date
EP4136451A1 (en) 2023-02-22
CA3178835A1 (en) 2021-10-21
JP2023522003A (ja) 2023-05-26
BR112022020884A2 (pt) 2022-11-29
TW202204896A (zh) 2022-02-01
IL297284A (en) 2022-12-01
AR122422A1 (es) 2022-09-07
WO2021211935A1 (en) 2021-10-21
CN115427810A (zh) 2022-12-02
KR20230004496A (ko) 2023-01-06
AU2021257455A1 (en) 2022-10-20
US20230204588A1 (en) 2023-06-29

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