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MX2022008494A - Tratamiento de la fibrodisplasia osificante progresiva. - Google Patents

Tratamiento de la fibrodisplasia osificante progresiva.

Info

Publication number
MX2022008494A
MX2022008494A MX2022008494A MX2022008494A MX2022008494A MX 2022008494 A MX2022008494 A MX 2022008494A MX 2022008494 A MX2022008494 A MX 2022008494A MX 2022008494 A MX2022008494 A MX 2022008494A MX 2022008494 A MX2022008494 A MX 2022008494A
Authority
MX
Mexico
Prior art keywords
treatment
fibrodysplasia ossificans
ossificans progressiva
fop
activin
Prior art date
Application number
MX2022008494A
Other languages
English (en)
Inventor
Scott Mellis
Aristides Economides
Gary Herman
Neto Eduardo Forleo
Trotter Dinko Gonzalez
Andrew Rankin
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MX2022008494A publication Critical patent/MX2022008494A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)

Abstract

Se proporcionan métodos para tratar la fibrodisplasia osificante progresiva (FOP) en sujetos humanos. Dichos métodos implican la administración a un sujeto con FOP de una cantidad terapéuticamente eficaz de un antagonista de Activina A, tal como un anticuerpo contra Activina A.
MX2022008494A 2020-01-08 2021-01-08 Tratamiento de la fibrodisplasia osificante progresiva. MX2022008494A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202062958448P 2020-01-08 2020-01-08
US202063076691P 2020-09-10 2020-09-10
US202063081428P 2020-09-22 2020-09-22
PCT/US2021/012598 WO2021142191A1 (en) 2020-01-08 2021-01-08 Treatment of fibrodysplasia ossificans progressiva

Publications (1)

Publication Number Publication Date
MX2022008494A true MX2022008494A (es) 2022-10-10

Family

ID=74550734

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022008494A MX2022008494A (es) 2020-01-08 2021-01-08 Tratamiento de la fibrodisplasia osificante progresiva.

Country Status (12)

Country Link
US (1) US20210253685A1 (es)
EP (1) EP4087652A1 (es)
JP (1) JP2023510270A (es)
KR (1) KR20220139886A (es)
CN (1) CN115243763A (es)
AU (1) AU2021205929A1 (es)
BR (1) BR112022013589A2 (es)
CA (1) CA3164168A1 (es)
CL (1) CL2022001861A1 (es)
IL (1) IL294611A (es)
MX (1) MX2022008494A (es)
WO (1) WO2021142191A1 (es)

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Also Published As

Publication number Publication date
WO2021142191A1 (en) 2021-07-15
CN115243763A (zh) 2022-10-25
IL294611A (en) 2022-09-01
BR112022013589A2 (pt) 2022-09-13
EP4087652A1 (en) 2022-11-16
CA3164168A1 (en) 2021-07-15
JP2023510270A (ja) 2023-03-13
KR20220139886A (ko) 2022-10-17
CL2022001861A1 (es) 2023-02-24
US20210253685A1 (en) 2021-08-19
AU2021205929A1 (en) 2022-09-01

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