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MX2020014191A - Variantes de enzimas lipoliticas. - Google Patents

Variantes de enzimas lipoliticas.

Info

Publication number
MX2020014191A
MX2020014191A MX2020014191A MX2020014191A MX2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A MX 2020014191 A MX2020014191 A MX 2020014191A
Authority
MX
Mexico
Prior art keywords
polypeptide
seq
amino acid
lipolytic enzyme
enzyme variants
Prior art date
Application number
MX2020014191A
Other languages
English (en)
Inventor
Aloysius Wilhelmus Rudolphus Hubertus Teunissen
Jong René Marcel De
Neil Carr
Joke Anneleen Putseys
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of MX2020014191A publication Critical patent/MX2020014191A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D6/00—Other treatment of flour or dough before baking, e.g. cooling, irradiating or heating
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

La presente invención se refiere a un polipéptido variante que tiene actividad lipasa, en donde el polipéptido puede ser un polipéptido que tiene una secuencia de aminoácidos que tiene al menos un 70% de identidad con una secuencia de aminoácidos madura de SEQ ID NO: 1 o SEQ ID NO: 6, en donde el polipéptido comprende una sustitución de aminoácido en la posición 295 y al menos una sustitución de aminoácido adicional en la posición 113, 121, 179 y/o 284, donde las posiciones se definen con referencia a SEQ ID NO: 1 o SEQ ID NO: 6. La invención se refiere además a un proceso para preparar una masa en donde se usa un polipéptido como se describe en este documento y se prepara un producto horneado a partir de la masa.
MX2020014191A 2018-06-19 2019-06-18 Variantes de enzimas lipoliticas. MX2020014191A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18178445 2018-06-19
PCT/EP2019/065992 WO2019243312A1 (en) 2018-06-19 2019-06-18 Lipolytic enzyme variants

Publications (1)

Publication Number Publication Date
MX2020014191A true MX2020014191A (es) 2021-03-09

Family

ID=62712840

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020014191A MX2020014191A (es) 2018-06-19 2019-06-18 Variantes de enzimas lipoliticas.

Country Status (7)

Country Link
US (1) US20210115418A1 (es)
EP (1) EP3809852A1 (es)
CN (1) CN112292037B (es)
BR (1) BR112020025589A2 (es)
MX (1) MX2020014191A (es)
WO (1) WO2019243312A1 (es)
ZA (1) ZA202007357B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023116569A1 (en) 2021-12-21 2023-06-29 Novozymes A/S Composition comprising a lipase and a booster
WO2024121058A1 (en) 2022-12-05 2024-06-13 Novozymes A/S A composition comprising a lipase and a peptide

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
ES2109238T3 (es) 1989-07-07 1998-01-16 Unilever Nv Procedimiento para la preparacion de una proteina mediante un hongo transformado por integracion multicopia de un vector de expresion.
DK76893D0 (es) 1993-06-28 1993-06-28 Novo Nordisk As
EP0635574B1 (en) 1993-07-23 2003-04-23 Dsm N.V. Selection marker gene free recombinant strains, a method for obtaining them and the use of these strains
WO1998026057A1 (en) 1996-12-09 1998-06-18 Novo Nordisk A/S Reduction of phosphorus containing components in edible oils comprising a high amount of non-hydratable phosphorus by use of a phospholipase, a phospholipase from a filamentous fungus having phospholipase a and/or b activity
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
JP5303084B2 (ja) 1997-04-11 2013-10-02 コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ 工業的組み換え生物を溝築するための手段としての遺伝子変換
DK1042461T3 (da) 1997-12-22 2007-09-24 Dsm Ip Assets Bv Ekspressionskloning i filiforme svampe
ID27054A (id) 1998-05-19 2001-02-22 Dsm Nv Perbaikan produksi sepalosporin di dalam organisme yang hidup
DK1117798T3 (da) 1998-10-05 2007-04-10 Novozymes As Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider
JP2002533092A (ja) 1998-12-22 2002-10-08 デーエスエム・ナムローゼ・フェンノートシャップ セファロスポリンの改良されたｉｎｖｉｖｏ産生
ATE469223T1 (de) 2000-03-14 2010-06-15 Novozymes As Pilz transkriptionsaktivator zur verwendung in verfahren zur herstellung von polypeptiden
WO2004074468A1 (en) 2002-05-30 2004-09-02 Dsm Ip Assets B.V. Novel pectinases and uses thereof
EP1625216B1 (en) * 2003-05-09 2012-11-21 Novozymes A/S Variant lipolytic enzymes
CN101094919B (zh) 2004-10-12 2014-09-03 帝斯曼知识产权资产管理有限公司 在生产多肽的方法中有用的真菌转录活化因子
DK2410048T3 (en) 2005-01-24 2016-11-28 Dsm Ip Assets Bv A process for the preparation of a compound of interest in a filamentous fungal cell
CN101454455A (zh) 2005-11-29 2009-06-10 帝斯曼知识产权资产管理有限公司 在基因表达中有用的转录激活因子的dna结合位点
US8812247B2 (en) 2006-06-29 2014-08-19 Dsm Ip Assets B.V. Method for achieving improved polypeptide expression
JP2011512809A (ja) 2008-02-29 2011-04-28 ディーエスエム アイピー アセッツ ビー．ブイ． 短鎖脂肪に対して特異性の高いリパーゼおよびその使用
CA2758404A1 (en) 2009-04-22 2010-10-28 Dsm Ip Assets B.V. Process for the production of a recombinant polypeptide of interest
CA2761767A1 (en) * 2009-05-19 2010-11-25 Danisco A/S Use of amylase and lipolytic enzyme in bread
AU2010275672A1 (en) 2009-07-22 2012-02-02 Dsm Ip Assets B.V. Improved host cell for the production of a compound of interest
US8945898B2 (en) 2010-07-01 2015-02-03 Dsm Ip Assets B.V. Recombinant host cell with deficiency in non-ribosomal peptide synthase production
CN104603273B (zh) 2012-03-12 2019-09-10 帝斯曼知识产权资产管理有限公司 重组系统
CN105189730B (zh) 2012-07-19 2021-04-30 帝斯曼知识产权资产管理有限公司 淀粉酶缺陷菌株
US10035986B2 (en) 2012-07-19 2018-07-31 Dsm Ip Assets B.V. AgsE-deficient strain
US20170313997A1 (en) 2014-10-29 2017-11-02 Novozymes A/S Filamentous Fungal Double-Mutant Host Cells
WO2018114912A1 (en) * 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
US20200063166A1 (en) 2017-03-13 2020-02-27 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain

Also Published As

Publication number Publication date
US20210115418A1 (en) 2021-04-22
EP3809852A1 (en) 2021-04-28
BR112020025589A2 (pt) 2021-03-23
CN112292037A (zh) 2021-01-29
ZA202007357B (en) 2023-01-25
CN112292037B (zh) 2024-03-22
WO2019243312A1 (en) 2019-12-26

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