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MX2019009407A - Nuevas composiciones de vacuna que comprenden oligonucleotidos inmunoestimulantes. - Google Patents

Nuevas composiciones de vacuna que comprenden oligonucleotidos inmunoestimulantes.

Info

Publication number
MX2019009407A
MX2019009407A MX2019009407A MX2019009407A MX2019009407A MX 2019009407 A MX2019009407 A MX 2019009407A MX 2019009407 A MX2019009407 A MX 2019009407A MX 2019009407 A MX2019009407 A MX 2019009407A MX 2019009407 A MX2019009407 A MX 2019009407A
Authority
MX
Mexico
Prior art keywords
vaccine compositions
antigen
immunostimulatory oligonucleotides
novel vaccine
component
Prior art date
Application number
MX2019009407A
Other languages
English (en)
Inventor
Joseph Dominowski Paul
K Rai Sharath
Mary Sly Laurel
Patrick Cook Corey
Mwangi Duncan
L Foss Dennis
Lee Krebs Richard
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of MX2019009407A publication Critical patent/MX2019009407A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/008Leishmania antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/27Equine rhinopneumonitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invencion proporciona una composicion de vacuna que comprende un componente de antigeno y un componente de adyuvante, en la que el componente de adyuvante comprende un oligonucleotido inmunoestimulante de clase P y o bien una combinacion de una saponina y un esterol; o una fase oleosa que comprende un aceite y, opcionalmente, uno o mas emulsionantes, comprendiendo dicha fase oleosa el 2-20 % v / v de la composicion de vacuna, en la que dicho componente de antigeno es un antigeno del EHV o un antigeno de Leishmania.
MX2019009407A 2013-05-14 2015-11-13 Nuevas composiciones de vacuna que comprenden oligonucleotidos inmunoestimulantes. MX2019009407A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361823189P 2013-05-14 2013-05-14

Publications (1)

Publication Number Publication Date
MX2019009407A true MX2019009407A (es) 2019-09-26

Family

ID=50897961

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015015758A MX367268B (es) 2013-05-14 2014-05-12 Nuevas composiciones de vacuna que comprenden oligonucleotidos inmunoestimulantes.
MX2019009407A MX2019009407A (es) 2013-05-14 2015-11-13 Nuevas composiciones de vacuna que comprenden oligonucleotidos inmunoestimulantes.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2015015758A MX367268B (es) 2013-05-14 2014-05-12 Nuevas composiciones de vacuna que comprenden oligonucleotidos inmunoestimulantes.

Country Status (20)

Country Link
EP (2) EP3542819B1 (es)
JP (2) JP6505084B2 (es)
CN (2) CN108079290A (es)
AR (1) AR096277A1 (es)
AU (2) AU2014265649B2 (es)
BR (1) BR112015028748A2 (es)
CA (2) CA3027289A1 (es)
DK (1) DK3542819T3 (es)
ES (2) ES2742325T3 (es)
HK (1) HK1219426A1 (es)
HR (1) HRP20211452T1 (es)
HU (1) HUE056040T2 (es)
LT (1) LT3542819T (es)
MX (2) MX367268B (es)
PL (1) PL3542819T3 (es)
PT (2) PT3542819T (es)
RU (1) RU2627447C2 (es)
SI (1) SI3542819T1 (es)
WO (1) WO2014186291A1 (es)
ZA (1) ZA201507774B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10456459B2 (en) * 2015-07-20 2019-10-29 Zoetis Services Llc Liposomal adjuvant compositions
JP6975132B2 (ja) * 2015-07-20 2021-12-01 ゾエティス・サービシーズ・エルエルシー リポソームアジュバント組成物
BE1023538B1 (fr) * 2016-04-22 2017-04-26 Sil'innov Scrl Silices mésoporeuses et leur procédé de synthèse
TW202206098A (zh) * 2020-08-11 2022-02-16 美商碩騰服務公司 抗冠狀病毒疫苗

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7904021A (nl) * 1979-05-22 1980-04-29 Gist Brocades Nv Gecombineerd vaccin en werkwijze voor het bereiden van dit gecombineerd vaccin tegen door adeno achtige virussen veroorzaakte eiproduktiedalingen en door reo virus veroorzaakte ziekteverschijnselen.
US6803041B2 (en) * 2001-03-20 2004-10-12 Boehringer Ingelheim Vetmedica, Inc. Equine herpesvirus vaccine
CA2452545C (en) * 2001-07-27 2015-06-09 Wyeth West nile vaccine comprising live attenuated, inactivated or killed whole or subunit west nile virus
JP2005532067A (ja) * 2002-07-03 2005-10-27 コーリー ファーマシューティカル グループ,インコーポレイテッド 刺激性免疫応答用の核酸組成物
GB0409940D0 (en) * 2004-05-04 2004-06-09 Glaxosmithkline Biolog Sa Vaccine
US20070166800A1 (en) * 2006-01-13 2007-07-19 Haixiang Lin Immunogenic substances comprising a polyinosinic acid-polycytidilic acid based adjuvant
MX2009003398A (es) * 2006-09-27 2009-08-12 Coley Pharm Gmbh Analogos de oligonucleotidos cpg que contienen analogos t hidrofobos con actividad inmunoestimuladora mejorada.
MX2009003325A (es) * 2006-10-12 2009-04-09 Glaxosmithkline Biolog Sa Vacuna que comprende un adyuvante de emulsion de aceite en agua.
MX347471B (es) * 2010-05-28 2017-04-24 Zoetis Belgium S A Vacunas que comprenden colesterol y cpg como moleculas portadoras-adyuvantes unicas.
EP2637687B1 (en) * 2010-11-08 2021-01-06 Infectious Disease Research Institute Vaccines comprising non-specific nucleoside hydrolase and sterol 24-c-methyltransferase (smt) polypeptides for the treatment and diagnosis of leishmaniasis

Also Published As

Publication number Publication date
MX2015015758A (es) 2016-03-16
CN105263518B (zh) 2018-03-20
ES2742325T3 (es) 2020-02-13
RU2015146752A (ru) 2017-06-20
JP2019108328A (ja) 2019-07-04
CA3027289A1 (en) 2014-11-20
SI3542819T1 (sl) 2021-11-30
CN108079290A (zh) 2018-05-29
MX367268B (es) 2019-08-12
BR112015028748A2 (pt) 2017-09-19
PT2996719T (pt) 2019-09-03
JP2016518446A (ja) 2016-06-23
NZ713360A (en) 2021-06-25
PT3542819T (pt) 2021-10-14
DK3542819T3 (da) 2021-09-20
HUE056040T2 (hu) 2022-01-28
EP2996719B1 (en) 2019-06-26
LT3542819T (lt) 2021-11-10
ZA201507774B (en) 2017-09-27
PL3542819T3 (pl) 2022-01-10
RU2627447C2 (ru) 2017-08-08
HRP20211452T1 (hr) 2021-12-24
ES2894138T3 (es) 2022-02-11
AU2014265649B2 (en) 2017-10-19
AU2014265649A1 (en) 2015-11-12
WO2014186291A1 (en) 2014-11-20
EP3542819B1 (en) 2021-08-18
EP3542819A1 (en) 2019-09-25
CN105263518A (zh) 2016-01-20
AU2017232231A1 (en) 2017-10-12
JP6505084B2 (ja) 2019-04-24
EP2996719A1 (en) 2016-03-23
CA2911938C (en) 2019-07-16
AR096277A1 (es) 2015-12-16
HK1219426A1 (zh) 2017-04-07
CA2911938A1 (en) 2014-11-20

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