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MX2019006864A - Tratamiento de una enfermedad del tracto gastrointestinal con un inhibidor de factor de necrosis tumoral (tnf). - Google Patents

Tratamiento de una enfermedad del tracto gastrointestinal con un inhibidor de factor de necrosis tumoral (tnf).

Info

Publication number
MX2019006864A
MX2019006864A MX2019006864A MX2019006864A MX2019006864A MX 2019006864 A MX2019006864 A MX 2019006864A MX 2019006864 A MX2019006864 A MX 2019006864A MX 2019006864 A MX2019006864 A MX 2019006864A MX 2019006864 A MX2019006864 A MX 2019006864A
Authority
MX
Mexico
Prior art keywords
gastrointestinal tract
disease
treatment
tnf inhibitor
tnf
Prior art date
Application number
MX2019006864A
Other languages
English (en)
Inventor
Singh Sharat
Lawrence Jones Mitchell
Loren Wahl Christopher
Stylli Harry
Original Assignee
Progenity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenity Inc filed Critical Progenity Inc
Publication of MX2019006864A publication Critical patent/MX2019006864A/es

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Abstract

Esta descripción presenta métodos y composiciones para tratar enfermedades del tracto gastrointestinal con un inhibidor de TNF.
MX2019006864A 2016-12-14 2017-12-14 Tratamiento de una enfermedad del tracto gastrointestinal con un inhibidor de factor de necrosis tumoral (tnf). MX2019006864A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662434363P 2016-12-14 2016-12-14
US201762479118P 2017-03-30 2017-03-30
US201762545240P 2017-08-14 2017-08-14
US201762583768P 2017-11-09 2017-11-09
PCT/US2017/066485 WO2018112240A1 (en) 2016-12-14 2017-12-14 Treatment of a disease of the gastrointestinal tract with a tnf inhibitor

Publications (1)

Publication Number Publication Date
MX2019006864A true MX2019006864A (es) 2019-10-15

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Application Number Title Priority Date Filing Date
MX2019006864A MX2019006864A (es) 2016-12-14 2017-12-14 Tratamiento de una enfermedad del tracto gastrointestinal con un inhibidor de factor de necrosis tumoral (tnf).

Country Status (11)

Country Link
US (1) US20190343425A1 (es)
EP (2) EP3554342B1 (es)
JP (2) JP7150724B2 (es)
KR (1) KR102616436B1 (es)
CN (2) CN118873822A (es)
AU (2) AU2017378393B2 (es)
BR (1) BR112019011689A2 (es)
CA (1) CA3045307A1 (es)
MX (1) MX2019006864A (es)
TW (1) TW201834711A (es)
WO (1) WO2018112240A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2013158256A (ru) 2011-07-06 2015-07-10 Нестек С.А. АНАЛИЗЫ ДЛЯ ОБНАРУЖЕНИЯ НЕЙТРАЛИЗУЮЩИХ АУТОАНТИТЕЛ ДЛЯ БИОЛОГИЧЕСКОЙ ТЕРАПИИ TNFα
WO2016088104A2 (en) 2014-12-05 2016-06-09 Nestec S.A. Indirect homogeneous mobility shift assays for the detection of biologics in patient samples
WO2018183929A1 (en) * 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device
US10980482B2 (en) 2017-12-06 2021-04-20 James Phillip Jones Sampling capsule system and methods
CN112585165A (zh) 2018-04-25 2021-03-30 普罗米修斯生物科学公司 优化的抗tl1a抗体
USD891632S1 (en) * 2018-10-08 2020-07-28 Tidhar Dari Shalon Gastrointestinal sampling device
US20210100533A1 (en) * 2019-10-08 2021-04-08 11 Health and Technologies Inc. Systems and methods for analysis of urine and fecal matter
IL292419A (en) 2019-10-24 2022-06-01 Prometheus Biosciences Inc Human antibodies to TNF-like ligand 1a (tl1a) and uses thereof
WO2021105987A1 (en) * 2019-11-25 2021-06-03 Check-Cap Ltd. Sensor-less dc motor closed loop controller for imaging capsule
US20230053966A1 (en) * 2020-01-27 2023-02-23 Celero Systems, Inc. Ingestible medical device
US20230067979A1 (en) * 2020-01-31 2023-03-02 Cosmoaesthetics Pty Ltd An ingestible therapeutic device for the treatment of gastritis
KR102247483B1 (ko) * 2020-02-27 2021-05-04 주식회사 레인보우솔루션 경구형 물질 전달 장치
CN111714781B (zh) * 2020-06-24 2022-08-05 北京夏禾科技有限公司 一种牙齿美白组合及其使用方法
TWI768541B (zh) * 2020-11-12 2022-06-21 鄭靖蓉 引流淋巴液至靜脈之設備
WO2022109089A1 (en) * 2020-11-18 2022-05-27 Trustees Of Tufts College Spatially-selective sampling of gut microbiome
CN113040070A (zh) * 2020-12-15 2021-06-29 苏州大学 一种草鱼肠道菌群失调模型的建立方法
EP4389751A1 (en) 2021-09-03 2024-06-26 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
WO2023205701A1 (en) 2022-04-20 2023-10-26 Kumquat Biosciences Inc. Macrocyclic heterocycles and uses thereof
CN115251807B (zh) * 2022-09-26 2022-12-06 徐州医科大学 胶囊内窥镜系统

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IL47062A (en) 1975-04-10 1979-07-25 Yeda Res & Dev Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
US4190328A (en) 1978-12-01 1980-02-26 Levine Robert A Process for detection of blood-borne parasites
US4665077A (en) 1979-03-19 1987-05-12 The Upjohn Company Method for treating rejection of organ or skin grafts with 6-aryl pyrimidine compounds
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US4904582A (en) 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
IL85746A (en) 1988-03-15 1994-05-30 Yeda Res & Dev Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases
FI891226A (fi) 1988-04-28 1989-10-29 Univ Leland Stanford Junior Reseptordeterminanter i anti-t-celler foer behandling av autoimmunsjukdom.
WO1989012232A1 (en) 1988-06-08 1989-12-14 London Diagnostics, Inc. Assays utilizing sensitizer-induced production of detectable signals
WO1990008187A1 (en) 1989-01-19 1990-07-26 Dana Farber Cancer Institute Soluble two domain cd2 protein
DE69006018T3 (de) 1989-03-21 2004-01-15 Immune Response Corp Inc Impfung und methoden gegen krankheiten, die von pathologischen reaktionen der spezifischen t-zellen abstammen.
NZ234586A (en) 1989-07-19 1993-02-25 Arthur Allen Vandenbark Peptide of a t-cell receptor capable of inducing protection from immune-related disease
CA2485553A1 (en) 1989-09-05 1991-03-21 Immunex Corporation Tumor necrosis factor - .alpha. and - .beta. receptors
US5170801A (en) * 1990-10-02 1992-12-15 Glaxo Inc. Medical capsule device actuated by radio-frequency (rf) signal
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5314805A (en) 1991-10-28 1994-05-24 Molecular Probes, Inc. Dual-fluorescence cell viability assay using ethidium homodimer and calcein AM
PT1621554E (pt) 1992-08-21 2009-07-13 Univ Bruxelles Imunoglobtainas desprovidas de cadeias leves
KR100232688B1 (ko) 1992-09-15 1999-12-01 스코트 쥐. 홀퀴스트 종양 괴사 인자 길항제를 함유하는 tnf-의존성 염증 치료용 제약 조성물
US6180403B1 (en) 1999-10-28 2001-01-30 Isis Pharmaceuticals Inc. Antisense inhibition of tumor necrosis factor alpha converting enzyme (TACE) expression
US5705398A (en) 1994-03-02 1998-01-06 The Scripps Research Institute Methods for identifying inhibitors of LPS-mediated LBP binding
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
US6090382A (en) 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
SK284040B6 (sk) 1996-02-09 2004-08-03 Abbott Laboratories (Bermuda) Ltd. Ľudské protilátky k ľudskému TNFalfa, ich použitie, spôsob ich syntézy a farmaceutické prípravky s ich obsahom
US5763602A (en) 1996-10-01 1998-06-09 Li; Ying-Syi Methods of syntheses of phthalocyanine compounds
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
US6046319A (en) 1997-10-22 2000-04-04 University Technologies International, Inc. Antisense oligodeoxynucleotides regulating expression of TNF-α
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
WO1999042838A1 (en) 1998-02-18 1999-08-26 Dade Behring Inc. Chemiluminescent compositions for use in detection of multiple analytes
US6080580A (en) 1998-10-05 2000-06-27 Isis Pharmaceuticals Inc. Antisense oligonucleotide modulation of tumor necrosis factor-α (TNF-α) expression
US6228642B1 (en) 1998-10-05 2001-05-08 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of tumor necrosis factor-(α) (TNF-α) expression
US8636648B2 (en) * 1999-03-01 2014-01-28 West View Research, Llc Endoscopic smart probe
US6331530B1 (en) 1999-07-13 2001-12-18 The Trustees Of Columbia University In The City Of New York Hydrophilic carrier for photosensitizers that cleaves when they catalyze the formation of singlet oxygen
US6703248B1 (en) 1999-12-15 2004-03-09 Dade Behring Marburg Gmbh Particles for diagnostic and therapeutic use
US20050227935A1 (en) 2001-05-18 2005-10-13 Sirna Therapeutics, Inc. RNA interference mediated inhibition of TNF and TNF receptor gene expression using short interfering nucleic acid (siNA)
AU2003222253A1 (en) 2002-03-05 2003-09-22 Monogram Biosciences, Inc. Multiplex analysis using membrane-bound sensitizers
US20060127484A1 (en) 2002-07-05 2006-06-15 Speirs Christopher J Controlled release composition
JP2006506465A (ja) 2002-07-19 2006-02-23 アボツト・バイオテクノロジー・リミテツド TNFα関連疾患の治療
TWI250312B (en) 2002-10-11 2006-03-01 Delta Electronics Inc Illumination system with multiple lamps
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
WO2006006948A2 (en) 2002-11-14 2006-01-19 Dharmacon, Inc. METHODS AND COMPOSITIONS FOR SELECTING siRNA OF IMPROVED FUNCTIONALITY
US7977471B2 (en) 2002-11-14 2011-07-12 Dharmacon, Inc. siRNA targeting TNFα
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
US20060104968A1 (en) 2003-03-05 2006-05-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
US7402398B2 (en) 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
KR20060092254A (ko) 2003-09-23 2006-08-22 라이트 사이언시즈 코포레이션 표적화된 pdt 제제의 선택성을 증진시키는 표적 결합에의해 활성화된 일중항 산소 감광제
CA2559685A1 (en) 2004-03-26 2005-10-06 Lek Pharmaceuticals D.D. Gastroresistant pharmaceutical dosage form comprising n-(2-(2-phthalimidoethoxy)-acetyl)-l-alanyl-d-glutamic acid (lk-423)
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
CN101107038A (zh) * 2005-01-18 2008-01-16 皇家飞利浦电子股份有限公司 电控胶囊
WO2007024715A2 (en) 2005-08-19 2007-03-01 Abbott Laboratories Dual variable domain immunoglobin and uses thereof
US7612181B2 (en) 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
JP2009541298A (ja) * 2006-06-20 2009-11-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 胃腸障害を処置するための電子カプセル
JP2009541018A (ja) * 2006-06-23 2009-11-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 薬剤投与システム
MY162024A (en) 2006-08-28 2017-05-31 La Jolla Inst Allergy & Immunology Antagonistic human light-specific human monoclonal antibodies
WO2011004395A1 (en) 2009-07-06 2011-01-13 Intas Biopharmaceuticals Limited Microemulsion formulation for biologicals
US20120136209A1 (en) * 2009-08-05 2012-05-31 Tel Hashomer Medical Research Infrastructure And Services, Ltd. Methods and devices for providing information useful in the diagnosis of abnormalities of the gastrointestinal tract
US9415004B2 (en) * 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
US8884006B2 (en) 2011-09-19 2014-11-11 University Of Puerto Rico Small-molecule inhibitors of Rac1 in metastatic breast cancer
WO2013113326A1 (en) 2012-01-31 2013-08-08 Curevac Gmbh Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
FR2986432B1 (fr) 2012-02-06 2014-03-14 Univ Lille Ii Droit & Sante Proteines 28kda gst provenant de schistosomes pour leur utilisation dans le traitement des maladies inflammatoires auto-immunes engendrant une reponse de type th1 et/ou th17
US20130315913A1 (en) 2012-03-26 2013-11-28 Sanofi Anti-light antibody therapy for inflammatory bowel disease
EP2970399B1 (en) * 2013-03-13 2021-11-10 Emory University Protein particles comprising disulfide crosslinkers and uses related thereto
US10961508B2 (en) 2013-04-12 2021-03-30 Kyoto University Method for inducing alveolar epithelial progenitor cells
KR20160010621A (ko) 2013-05-24 2016-01-27 네스텍 소시에테아노님 과민성 대장 증후군의 진단을 위한 경로 특이적 마커
PL226431B1 (pl) 2013-08-23 2017-07-31 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Cząsteczka miRNA do zastosowania do wytwarzania leku do zmniejszania reakcji zapalnej lub zapobiegania zwiększaniu się reakcji zapalnej organizmu
CN105916541A (zh) * 2013-09-26 2016-08-31 医学量度个性化药物输送有限公司 具有阈值释放装置的传送胶囊
GB201319792D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CN105814081B (zh) 2013-11-13 2021-02-02 辉瑞大药厂 肿瘤坏死因子样配体1a特异性抗体及其组合物和用途
WO2015099749A1 (en) * 2013-12-27 2015-07-02 Capso Vision Inc. Capsule camera device with multi-spectral light sources
KR102056963B1 (ko) 2013-12-30 2019-12-17 에피맙 바이오테라퓨틱스 인코포레이티드 Fabs-인-탠덤 면역글로불린 및 이의 용도
WO2015112575A1 (en) 2014-01-22 2015-07-30 The Board Of Regents Of The University Of Nebraska Gastrointestinal sensor implantation system
EP3757224A3 (en) * 2014-02-27 2021-03-17 Biogen MA Inc. Method of assessing risk of pml
MX2017001971A (es) 2014-08-13 2017-09-15 Cedars Sinai Medical Center Composiciones antimetanogenicas y sus usos.
JP6648120B2 (ja) * 2014-09-25 2020-02-14 プロジェニティ, インコーポレイテッド 局所化能力を有する電気機械丸薬デバイス
US9714288B2 (en) 2014-09-30 2017-07-25 The Regents Of The University Of California Antisense compounds and uses thereof
US9750923B2 (en) * 2014-11-19 2017-09-05 Velóce Corporation Wireless communications system integrating electronics into orally ingestible products for controlled release of active ingredients
CN104473611B (zh) 2015-01-19 2018-01-30 吉林大学 具有超声波定位功能的胶囊内窥镜系统
CA2978604A1 (en) 2015-03-06 2016-09-15 Synthetic Biologics, Inc. Safe and effective beta-lactamase dosing for microbiome protection
EA035638B1 (ru) 2015-03-31 2020-07-20 ВиЭйчСКВЕАРД ЛИМИТЕД Полипептиды
ES2716900T3 (es) * 2015-11-06 2019-06-17 Promise Advanced Proteomics Un método para cuantificar anticuerpos anti-TNF
DK3219727T3 (da) 2016-03-17 2021-01-04 Tillotts Pharma Ag Anti-THF-alpha-antistoffer og funktionelle fragmenter deraf
EP3435982A1 (en) 2016-03-31 2019-02-06 VHsquared Limited Compositions

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