MX2019003298A - Proteinas de union recombinantes y sus usos. - Google Patents
Proteinas de union recombinantes y sus usos.Info
- Publication number
- MX2019003298A MX2019003298A MX2019003298A MX2019003298A MX2019003298A MX 2019003298 A MX2019003298 A MX 2019003298A MX 2019003298 A MX2019003298 A MX 2019003298A MX 2019003298 A MX2019003298 A MX 2019003298A MX 2019003298 A MX2019003298 A MX 2019003298A
- Authority
- MX
- Mexico
- Prior art keywords
- binding proteins
- recombinant binding
- nucleic acids
- recombinant
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se desvelan nuevas proteínas de unión recombinantes, que comprenden dominios diseñados con repeticiones de anquirina con especificidad de unión para el HER2, y que comprenden dominios diseñados con repeticiones de anquirina con especificidad de unión para la seroalbúmina, así como los ácidos nucleicos que codifican dichas proteínas de unión recombinantes, composiciones farmacéuticas que comprenden dichas proteínas de unión recombinantes o ácidos nucleicos y el uso de dichas proteínas de unión recombinantes, ácidos nucleicos o composiciones farmacéuticas en el tratamiento de enfermedades.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16190221 | 2016-09-22 | ||
PCT/EP2017/073768 WO2018054971A1 (en) | 2016-09-22 | 2017-09-20 | Recombinant binding proteins and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019003298A true MX2019003298A (es) | 2019-09-26 |
Family
ID=57046984
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019003298A MX2019003298A (es) | 2016-09-22 | 2017-09-20 | Proteinas de union recombinantes y sus usos. |
Country Status (20)
Country | Link |
---|---|
US (2) | US10717772B2 (es) |
EP (1) | EP3515933B9 (es) |
JP (1) | JP6976335B2 (es) |
KR (1) | KR102270315B1 (es) |
CN (1) | CN109790206A (es) |
AR (1) | AR109680A1 (es) |
AU (1) | AU2017331329B2 (es) |
BR (1) | BR112019005587A2 (es) |
CA (1) | CA3036301C (es) |
CL (1) | CL2019000729A1 (es) |
CO (1) | CO2019002609A2 (es) |
ES (1) | ES2953516T3 (es) |
IL (1) | IL265489B (es) |
MX (1) | MX2019003298A (es) |
MY (1) | MY196882A (es) |
NZ (1) | NZ751689A (es) |
PH (1) | PH12019500596A1 (es) |
SA (1) | SA519401369B1 (es) |
WO (1) | WO2018054971A1 (es) |
ZA (1) | ZA201901592B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114222757A (zh) * | 2019-06-04 | 2022-03-22 | 分子伴侣公司 | 重组4-1bb结合蛋白及其用途 |
BR112021024237A2 (pt) | 2019-06-04 | 2022-04-19 | Molecular Partners Ag | Domínio de repetição de anquirina projetado com estabilidade aprimorada |
SG11202112921VA (en) | 2019-06-04 | 2021-12-30 | Molecular Partners Ag | Multispecific proteins |
AU2020286600A1 (en) * | 2019-06-04 | 2021-12-23 | Molecular Partners Ag | Recombinant FAP binding proteins and their use |
KR20220113491A (ko) | 2019-12-11 | 2022-08-12 | 몰리큘라 파트너스 아게 | 재조합 펩티드-mhc 복합체 결합 단백질 및 이의 생성 및 용도 |
EP4146691A1 (en) | 2020-05-06 | 2023-03-15 | Molecular Partners AG | Novel ankyrin repeat binding proteins and their uses |
CA3178478A1 (en) * | 2020-05-14 | 2021-11-18 | Valerie Perrine Calabro | Recombinant cd40 binding proteins and their use |
CA3178785A1 (en) | 2020-05-14 | 2021-11-18 | Nicolo RIGAMONTI | Multispecific proteins |
WO2022130300A1 (en) | 2020-12-16 | 2022-06-23 | Molecular Partners Ag | Novel slow-release prodrugs |
AU2022234894A1 (en) | 2021-03-09 | 2023-10-05 | Molecular Partners Ag | Novel darpin based multi-specific t-cell engagers |
WO2022190018A1 (en) | 2021-03-09 | 2022-09-15 | Molecular Partners Ag | Novel darpin based cd123 engagers |
US20240317852A1 (en) | 2021-03-09 | 2024-09-26 | Molecular Partners Ag | Novel darpin based cd33 engagers |
JP2024509890A (ja) | 2021-03-09 | 2024-03-05 | モレキュラー パートナーズ アクチェンゲゼルシャフト | プロテアーゼ切断可能なプロドラッグ |
CA3239407A1 (en) | 2021-12-14 | 2023-06-22 | Simon FONTAINE | Designed repeat domains with dual binding specificity and their use |
US20240228545A9 (en) | 2022-08-01 | 2024-07-11 | Molecular Partners Ag | Charge modified designed repeat domains and their use |
WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
US20240368250A1 (en) | 2023-02-17 | 2024-11-07 | Ablynx N.V. | Polypeptides binding to the neonatal fc receptor |
WO2024179981A1 (en) | 2023-02-27 | 2024-09-06 | Molecular Partners Ag | Darpins for use in reducing renal accumulation of drugs |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
US7371376B1 (en) | 1996-10-18 | 2008-05-13 | Genentech, Inc. | Anti-ErbB2 antibodies |
US7417130B2 (en) | 2000-09-08 | 2008-08-26 | University Of Zurich | Collection of repeat proteins comprising repeat modules |
WO2003018611A2 (en) * | 2001-08-24 | 2003-03-06 | University Of Victoria Innovation And Development Corporation | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
NZ591733A (en) | 2004-11-12 | 2012-10-26 | Bayer Schering Pharma Ag | Recombinant newcastle disease virus comprising a transgene encoding a fusion protein comprising a binding domain and a heterologous domain comprising an enzyme |
PL1902131T3 (pl) | 2005-07-08 | 2010-05-31 | Univ Zuerich | Prezentacja fagowa z zastosowaniem kotranslacyjnej translokacji polipeptydów fuzyjnych |
US9365629B2 (en) | 2007-09-24 | 2016-06-14 | University Of Zurich | Designed armadillo repeat proteins |
CA2706200A1 (en) | 2007-11-27 | 2009-06-04 | Ablynx N.V. | Immunoglobulin constructs comprising multiple single variable domains and an fc portion |
EP3785735A1 (en) | 2008-11-03 | 2021-03-03 | Molecular Partners AG | Binding proteins inhibiting the vegf-a receptor interaction |
AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
CN113278077A (zh) | 2010-11-26 | 2021-08-20 | 分子组合公司 | 设计的与血清白蛋白结合的重复蛋白 |
WO2012149439A2 (en) | 2011-04-29 | 2012-11-01 | Janssen Biotech, Inc. | Il4/il13 binding repeat proteins and uses |
CA2877584A1 (en) | 2012-06-28 | 2014-01-03 | Molecular Partners Ag | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
AU2013331763B2 (en) * | 2012-10-15 | 2018-02-15 | Universitat Zurich | Bispecific HER2 ligands for cancer therapy |
EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
CN105209483B (zh) | 2013-05-31 | 2021-07-27 | 分子组合公司 | 与肝细胞生长因子结合的设计锚蛋白重复蛋白 |
AU2016240220B2 (en) | 2015-04-02 | 2019-11-21 | Molecular Partners Ag | Designed ankyrin repeat domains with binding specificity for serum albumin |
-
2017
- 2017-09-20 AU AU2017331329A patent/AU2017331329B2/en active Active
- 2017-09-20 JP JP2019536693A patent/JP6976335B2/ja active Active
- 2017-09-20 WO PCT/EP2017/073768 patent/WO2018054971A1/en active Application Filing
- 2017-09-20 EP EP17778226.5A patent/EP3515933B9/en active Active
- 2017-09-20 MX MX2019003298A patent/MX2019003298A/es active IP Right Grant
- 2017-09-20 KR KR1020197009396A patent/KR102270315B1/ko active IP Right Grant
- 2017-09-20 AR ARP170102593A patent/AR109680A1/es unknown
- 2017-09-20 BR BR112019005587A patent/BR112019005587A2/pt not_active Application Discontinuation
- 2017-09-20 US US15/710,001 patent/US10717772B2/en active Active
- 2017-09-20 CA CA3036301A patent/CA3036301C/en active Active
- 2017-09-20 CN CN201780058511.0A patent/CN109790206A/zh active Pending
- 2017-09-20 MY MYPI2019001523A patent/MY196882A/en unknown
- 2017-09-20 ES ES17778226T patent/ES2953516T3/es active Active
- 2017-09-20 NZ NZ751689A patent/NZ751689A/en unknown
-
2019
- 2019-03-14 ZA ZA2019/01592A patent/ZA201901592B/en unknown
- 2019-03-19 PH PH12019500596A patent/PH12019500596A1/en unknown
- 2019-03-19 IL IL265489A patent/IL265489B/en unknown
- 2019-03-20 SA SA519401369A patent/SA519401369B1/ar unknown
- 2019-03-21 CO CONC2019/0002609A patent/CO2019002609A2/es unknown
- 2019-03-21 CL CL2019000729A patent/CL2019000729A1/es unknown
-
2020
- 2020-06-22 US US16/907,415 patent/US20210130420A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA3036301A1 (en) | 2018-03-29 |
WO2018054971A1 (en) | 2018-03-29 |
EP3515933B1 (en) | 2023-06-07 |
CN109790206A (zh) | 2019-05-21 |
PH12019500596A1 (en) | 2019-07-29 |
EP3515933B9 (en) | 2023-08-16 |
ZA201901592B (en) | 2021-04-28 |
CO2019002609A2 (es) | 2019-05-31 |
AU2017331329A1 (en) | 2019-04-04 |
EP3515933C0 (en) | 2023-06-07 |
AU2017331329B2 (en) | 2020-10-29 |
IL265489A (en) | 2019-05-30 |
CA3036301C (en) | 2021-04-20 |
IL265489B (en) | 2021-07-29 |
RU2019111628A (ru) | 2020-10-19 |
CL2019000729A1 (es) | 2019-06-14 |
NZ751689A (en) | 2021-07-30 |
JP2019531093A (ja) | 2019-10-31 |
ES2953516T3 (es) | 2023-11-14 |
MY196882A (en) | 2023-05-08 |
BR112019005587A2 (pt) | 2019-06-11 |
AR109680A1 (es) | 2019-01-09 |
SA519401369B1 (ar) | 2022-12-22 |
RU2019111628A3 (es) | 2020-10-30 |
US10717772B2 (en) | 2020-07-21 |
JP6976335B2 (ja) | 2021-12-08 |
US20180155402A1 (en) | 2018-06-07 |
US20210130420A1 (en) | 2021-05-06 |
KR102270315B1 (ko) | 2021-06-29 |
KR20190050802A (ko) | 2019-05-13 |
EP3515933A1 (en) | 2019-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |