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MX2017012220A - Composiciones adyuvantes y metodos relacionados. - Google Patents

Composiciones adyuvantes y metodos relacionados.

Info

Publication number
MX2017012220A
MX2017012220A MX2017012220A MX2017012220A MX2017012220A MX 2017012220 A MX2017012220 A MX 2017012220A MX 2017012220 A MX2017012220 A MX 2017012220A MX 2017012220 A MX2017012220 A MX 2017012220A MX 2017012220 A MX2017012220 A MX 2017012220A
Authority
MX
Mexico
Prior art keywords
present disclosure
related methods
composition
adjuvant compositions
adjuvant composition
Prior art date
Application number
MX2017012220A
Other languages
English (en)
Inventor
J Miller Timothy
Ann Pfannenstiel Mary
Original Assignee
Vaxliant Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxliant Llc filed Critical Vaxliant Llc
Publication of MX2017012220A publication Critical patent/MX2017012220A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente descripción proporciona una composición adyuvante que es adecuada para administración inyectable, así como transdérmica. La composición adyuvante, en general, comprende un lipófilo, un polímero de ácido acrílico o metacrílico, solución salina, colesterol, una saponina e hidróxido de sodio. También se proporciona una composición de vacuna que incluye, en general, la composición de vacuna de la presente descripción y un componente de ADN. También se proporciona un método de vacunación de animales y humanos que utiliza la composición adyuvante de la presente descripción.
MX2017012220A 2015-03-24 2016-03-24 Composiciones adyuvantes y metodos relacionados. MX2017012220A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562137659P 2015-03-24 2015-03-24
PCT/US2016/024003 WO2016154432A1 (en) 2015-03-24 2016-03-24 Adjuvant compositions and related methods

Publications (1)

Publication Number Publication Date
MX2017012220A true MX2017012220A (es) 2018-02-09

Family

ID=56973861

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017012220A MX2017012220A (es) 2015-03-24 2016-03-24 Composiciones adyuvantes y metodos relacionados.

Country Status (8)

Country Link
US (2) US9636397B2 (es)
EP (1) EP3273950A4 (es)
JP (1) JP6925277B2 (es)
AU (1) AU2016235059B2 (es)
BR (1) BR112017020175A2 (es)
CA (1) CA2979556C (es)
MX (1) MX2017012220A (es)
WO (1) WO2016154432A1 (es)

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* Cited by examiner, † Cited by third party
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US10195261B2 (en) * 2014-11-26 2019-02-05 VaxLiant, LLC Adjuvant compositions and related methods
CA2979556C (en) * 2015-03-24 2023-07-18 VaxLiant, LLC Adjuvant compositions and related methods
GB201616904D0 (en) * 2016-10-05 2016-11-16 Glaxosmithkline Biologicals Sa Vaccine
US11197928B2 (en) 2017-01-13 2021-12-14 Board Of Regents, The University Of Texas System Sustained production of high affinity antigen specific antibody by high dose BAFF receptor-targeting mAb-siRNA conjugate
WO2018222874A1 (en) 2017-05-31 2018-12-06 Texas Tech University System Methods and devices for the treatment of food allergies
JP7542257B2 (ja) 2018-01-25 2024-08-30 エイシーエム バイオラブズ プライベート リミテッド 可溶化された封入抗原を含むポリマーソーム、ならびにその作製および使用方法
CA3106341A1 (en) * 2018-07-13 2020-01-16 Biomune Company New vaccines against avian reoviruses
EP3849600A1 (en) 2018-09-12 2021-07-21 ACM Biolabs Pte Ltd Polymersomes comprising a covalently bound antigen as well as methods of making and uses thereof
CA3143533A1 (en) 2019-08-01 2021-02-04 Madhavan Nallani A method of eliciting an immune response by administering a population of polymersomes having an associated antigen together with a population of polymersomes having an associated adjuvant as well as compositions comprising the two populations of polymersome
CA3172716A1 (en) 2020-04-24 2021-10-28 Madhavan Nallani Vaccine against human-pathogenic coronaviruses
IL299546A (en) * 2020-07-03 2023-02-01 Statens Seruminstitut Plasmid DNA for SARS corona virus 2 / vaccine for COVID-19
CA3193643A1 (en) 2020-12-11 2022-06-16 Madhavan Nallani Modulating th1/th2 immune response by administering two populations of polymersomes having an associated antigen and an associated adjuvant
CA3204785A1 (en) 2021-02-02 2022-08-11 Madhavan Nallani Sole use of polymersome associated adjuvant for stimulating an immune response
CA3214934A1 (en) 2021-04-12 2022-10-20 Madhavan Nallani Polymersomes comprising a soluble encapsulated polynucleotide and an ionizable lipid as well as methods of making and uses thereof
CN113913395B (zh) * 2021-10-19 2022-06-14 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 人工重组的h5n8流感病毒及其制备方法和应用
AU2023226175A1 (en) 2022-02-23 2024-10-03 Acm Biolabs Pte Ltd Polymer-lipid hybrid nanoparticles comprising a lipid and a block copolymer as well as methods of making and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
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US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US5961970A (en) * 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
US20080292663A1 (en) * 2007-05-22 2008-11-27 Gerber Jay D Adjuvant compositions and methods for delivering vaccines
CN102076358B (zh) * 2008-06-27 2016-08-17 硕腾有限责任公司 新颖的佐剂组合物
WO2010011605A2 (en) * 2008-07-21 2010-01-28 Otonomy, Inc. Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
US20110207952A1 (en) * 2010-02-22 2011-08-25 Rafael Avila Cholesterol extraction from algae and preparation of vegan vitamin d3
US20150044242A1 (en) * 2012-03-12 2015-02-12 Advanced Bioadjuvants Llc Adjuvant and Vaccine Compositions
BR122019025678B1 (pt) 2012-11-01 2023-04-18 Factor Bioscience Inc Composições que compreendem ácido nucleico que codifica uma proteína de edição gênica
US10195261B2 (en) 2014-11-26 2019-02-05 VaxLiant, LLC Adjuvant compositions and related methods
JP6802790B2 (ja) * 2014-11-26 2020-12-23 ヒューベファーマ・インコーポレイテッドＨｕｖｅｐｈａｒｍａ， Ｉｎｃ． アジュバント組成物及び関連方法
CA2979556C (en) * 2015-03-24 2023-07-18 VaxLiant, LLC Adjuvant compositions and related methods

Also Published As

Publication number Publication date
US9636397B2 (en) 2017-05-02
AU2016235059A1 (en) 2017-10-05
WO2016154432A1 (en) 2016-09-29
JP6925277B2 (ja) 2021-08-25
JP2018510874A (ja) 2018-04-19
EP3273950A4 (en) 2019-04-24
EP3273950A1 (en) 2018-01-31
CA2979556A1 (en) 2016-09-29
CA2979556C (en) 2023-07-18
BR112017020175A2 (pt) 2018-06-12
US20170202959A1 (en) 2017-07-20
US20160279237A1 (en) 2016-09-29
NZ735525A (en) 2024-05-31
US10265395B2 (en) 2019-04-23
AU2016235059B2 (en) 2021-04-01

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