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MX2017008751A - Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs). - Google Patents

Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs).

Info

Publication number
MX2017008751A
MX2017008751A MX2017008751A MX2017008751A MX2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A MX 2017008751 A MX2017008751 A MX 2017008751A
Authority
MX
Mexico
Prior art keywords
chimeric protein
porcine respiratory
prrs
diagnosis
prevention
Prior art date
Application number
MX2017008751A
Other languages
Spanish (es)
Inventor
Gutierrez Ortega Abel
Hernandez Gutierrez Rodolfo
Amanda Camacho Villegas Tanya
Alberto MANUEL CABRERA Carlos
Gaona Bernal Jorge
MARTÍNEZ VELÁZQUEZ Moisés
Original Assignee
Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C filed Critical Centro De Investig Y Asistencia En Tecnologia Y Diseno Del Estado De Jalisco A C
Priority to MX2017008751A priority Critical patent/MX2017008751A/en
Priority to PCT/MX2018/000052 priority patent/WO2019004811A1/en
Publication of MX2017008751A publication Critical patent/MX2017008751A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)

Abstract

The present invention relates to a chimeric protein comprising short sequences from some of the structural proteins in porcine respiratory and reproductive syndrome virus (PRRSV). The protein is used as capture antigen in an enzyme-linked immunoadsorption assay for the detection of antibodies present in sera from pigs infected with the virus. The protein is also administered to piglets and induces a rapid antibody response, thereby acting as an immunising agent for the control of PRRSV in the early stages of pig growth.
MX2017008751A 2017-06-29 2017-06-29 Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs). MX2017008751A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
MX2017008751A MX2017008751A (en) 2017-06-29 2017-06-29 Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs).
PCT/MX2018/000052 WO2019004811A1 (en) 2017-06-29 2018-06-13 Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2017008751A MX2017008751A (en) 2017-06-29 2017-06-29 Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs).

Publications (1)

Publication Number Publication Date
MX2017008751A true MX2017008751A (en) 2019-02-08

Family

ID=64742556

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017008751A MX2017008751A (en) 2017-06-29 2017-06-29 Chimeric protein for the prevention and diagnosis of porcine respiratory and reproductive syndrome (prrs).

Country Status (2)

Country Link
MX (1) MX2017008751A (en)
WO (1) WO2019004811A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110894243B (en) * 2019-12-16 2021-07-13 中国农业大学 Porcine reproductive and respiratory syndrome virus chimeric antigen and colloidal gold immunochromatographic test strip for detecting porcine reproductive and respiratory syndrome virus antibody

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106075422B (en) * 2005-11-29 2021-05-28 衣阿华州立大学研究基金公司 Identification of protective antigenic determinants of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and uses thereof
US7465455B2 (en) * 2006-07-05 2008-12-16 Healthbanks Biotech Co., Ltd. Fusion protein of porcine reproductive and respiratory syndrome virus as PRRS vaccine
EP2457583A1 (en) * 2010-11-26 2012-05-30 Consejo Superior De Investigaciones Cientificas Nucleic acids encoding PRRSV GP5-ecto and M protein
EP2804000A1 (en) * 2013-05-15 2014-11-19 Prionics AG Method for the detection and classification of PRRSV-infections in swine herds and diagnostic antigen compositions for such methods
CN107847575B (en) * 2015-06-01 2021-12-17 瑞宝基因股份有限公司 Vaccine composition for porcine reproductive and respiratory syndrome and porcine circovirus related diseases
TWI737617B (en) * 2015-06-23 2021-09-01 美商百靈佳殷格翰動物保健美國有限公司 Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof

Also Published As

Publication number Publication date
WO2019004811A1 (en) 2019-01-03

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