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MX2016005572A - Uso de monensina para regular la glicosilacion de proteinas recombinantes. - Google Patents

Uso de monensina para regular la glicosilacion de proteinas recombinantes.

Info

Publication number
MX2016005572A
MX2016005572A MX2016005572A MX2016005572A MX2016005572A MX 2016005572 A MX2016005572 A MX 2016005572A MX 2016005572 A MX2016005572 A MX 2016005572A MX 2016005572 A MX2016005572 A MX 2016005572A MX 2016005572 A MX2016005572 A MX 2016005572A
Authority
MX
Mexico
Prior art keywords
monensin
recombinant proteins
glycosylation
regulate
regulate glycosylation
Prior art date
Application number
MX2016005572A
Other languages
English (en)
Inventor
Mujacic Mirna
Pande Sandhya
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51905413&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016005572(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2016005572A publication Critical patent/MX2016005572A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporcionan métodos para modular el alto contenido glicoforme de manosa de una proteína en un cultivo celular al poner en contacto las células que expresan la proteína de interés con monensina.
MX2016005572A 2013-10-31 2014-10-30 Uso de monensina para regular la glicosilacion de proteinas recombinantes. MX2016005572A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361898310P 2013-10-31 2013-10-31
PCT/US2014/063211 WO2015066357A1 (en) 2013-10-31 2014-10-30 Use of monensin to regulate glycosylation of recombinant proteins

Publications (1)

Publication Number Publication Date
MX2016005572A true MX2016005572A (es) 2016-12-09

Family

ID=51905413

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016005572A MX2016005572A (es) 2013-10-31 2014-10-30 Uso de monensina para regular la glicosilacion de proteinas recombinantes.

Country Status (7)

Country Link
US (2) US11130980B2 (es)
EP (1) EP3063287A1 (es)
JP (1) JP6621744B2 (es)
AU (2) AU2014342232B2 (es)
CA (1) CA2929077C (es)
MX (1) MX2016005572A (es)
WO (1) WO2015066357A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE033279T2 (en) 2011-07-01 2017-11-28 Amgen Inc Mammalian cell culture
JP2018531619A (ja) * 2015-11-02 2018-11-01 アレス トレーディング ソシエテ アノニム 灌流様式において組換えたんぱく質の生産プロファイルを調節する方法
US11566062B2 (en) 2017-12-20 2023-01-31 Ares Trading S.A. Methods for modulating protein mannosylation profiles using maduramycin, narasin, or salinomycin
JP7536651B2 (ja) 2018-05-01 2024-08-20 アムジエン・インコーポレーテツド 調節されたグリカンプロファイルを有する抗体
WO2023190829A1 (ja) 2022-03-31 2023-10-05 富士フイルム株式会社 生産物の製造方法、及び生産物

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Also Published As

Publication number Publication date
JP6621744B2 (ja) 2019-12-18
AU2018201844A1 (en) 2018-04-12
EP3063287A1 (en) 2016-09-07
US11299760B2 (en) 2022-04-12
CA2929077A1 (en) 2015-05-07
US20160281124A1 (en) 2016-09-29
WO2015066357A1 (en) 2015-05-07
CA2929077C (en) 2024-05-28
JP2016534732A (ja) 2016-11-10
US20210395793A1 (en) 2021-12-23
US11130980B2 (en) 2021-09-28
AU2014342232B2 (en) 2017-12-21
AU2018201844B2 (en) 2019-05-30
AU2014342232A1 (en) 2016-08-25

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