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MX2015015589A - Composiciones y metodos para el suministro de agentes activos hidrófobos. - Google Patents

Composiciones y metodos para el suministro de agentes activos hidrófobos.

Info

Publication number
MX2015015589A
MX2015015589A MX2015015589A MX2015015589A MX2015015589A MX 2015015589 A MX2015015589 A MX 2015015589A MX 2015015589 A MX2015015589 A MX 2015015589A MX 2015015589 A MX2015015589 A MX 2015015589A MX 2015015589 A MX2015015589 A MX 2015015589A
Authority
MX
Mexico
Prior art keywords
delivery
hydrophobic active
methods
agent
delivery composition
Prior art date
Application number
MX2015015589A
Other languages
English (en)
Inventor
Dale G Swan
Joram Slager
Darin Dumez
Joseph Ventura
Shannon Wadman
Joseph Schmidt Mcgonigle
Robert W Hergenrother
Original Assignee
Surmodics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/072,520 external-priority patent/US9555119B2/en
Application filed by Surmodics Inc filed Critical Surmodics Inc
Publication of MX2015015589A publication Critical patent/MX2015015589A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

En la presente se describe una composición de suministro para administrar un agente activo hidrófobo. En una modalidad, se describe una composición de suministro para la administración local de un agente activo hidrófobo a un tejido u órgano de un paciente. En una modalidad, la composición de suministro incluye un agente de suministro catiónico, una cantidad terapéuticamente eficaz de un agente activo hidrófobo; y un portador acuoso farmacéuticamente aceptable. En una modalidad, el agente de suministro catiónico incluye polietilenimina (PEI). En una modalidad, la invención incluye un dispositivo de suministro de fármacos que incluye un sustrato; y partículas con el agente terapéutico recubiertas dispuestas sobre el sustrato, comprendiendo las partículas con el agente terapéutico 0recubiertas un agente terapéutico hidrófobo particulado; y un polímero de tipo vinilamina. Los métodos para elaborar la composición de suministro. Así como también kits y métodos de uso también se incluyen en la presente.
MX2015015589A 2013-05-16 2014-05-16 Composiciones y metodos para el suministro de agentes activos hidrófobos. MX2015015589A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361824160P 2013-05-16 2013-05-16
US14/072,520 US9555119B2 (en) 2012-11-05 2013-11-05 Composition and method for delivery of hydrophobic active agents
PCT/US2014/038435 WO2014186729A1 (en) 2013-05-16 2014-05-16 Compositions and methods for delivery of hydrophobic active agents

Publications (1)

Publication Number Publication Date
MX2015015589A true MX2015015589A (es) 2016-07-05

Family

ID=51898903

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015015589A MX2015015589A (es) 2013-05-16 2014-05-16 Composiciones y metodos para el suministro de agentes activos hidrófobos.

Country Status (6)

Country Link
EP (1) EP2996735B1 (es)
JP (1) JP6469090B2 (es)
CA (1) CA2912690C (es)
IL (1) IL242545B (es)
MX (1) MX2015015589A (es)
WO (1) WO2014186729A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105214143A (zh) 2009-04-28 2016-01-06 苏尔莫迪克斯公司 用于递送生物活性剂的装置和方法
US10213529B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US9861727B2 (en) 2011-05-20 2018-01-09 Surmodics, Inc. Delivery of hydrophobic active agent particles
US9757497B2 (en) 2011-05-20 2017-09-12 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US9555119B2 (en) 2012-11-05 2017-01-31 Surmodics, Inc. Composition and method for delivery of hydrophobic active agents
US11246963B2 (en) 2012-11-05 2022-02-15 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
CA2974962C (en) * 2015-01-29 2024-01-09 Surmodics, Inc. Delivery of hydrophobic active agent particles
US10478546B2 (en) 2015-09-15 2019-11-19 Surmodics, Inc. Hemodialysis catheter sleeve
US20170281914A1 (en) * 2016-03-31 2017-10-05 Surmodics, Inc. Localized treatment of tissues through transcatheter delivery of active agents
US10918835B2 (en) * 2016-03-31 2021-02-16 Surmodics, Inc. Delivery system for active agent coated balloon
JP6929502B2 (ja) * 2016-11-14 2021-09-01 株式会社トップ 内視鏡用オーバーチューブ
US10898446B2 (en) 2016-12-20 2021-01-26 Surmodics, Inc. Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces
JP7073337B2 (ja) * 2017-03-16 2022-05-23 テルモ株式会社 バルーンカテーテルの製造方法
CN118019553A (zh) * 2021-10-05 2024-05-10 巴德血管外围设备公司 用于医疗设备的药物涂层
CN117258050B (zh) * 2023-11-22 2024-02-23 杭州亿科医疗科技有限公司 一种药物球囊及其制备方法

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US5195969A (en) 1991-04-26 1993-03-23 Boston Scientific Corporation Co-extruded medical balloons and catheter using such balloons
US5279607A (en) 1991-05-30 1994-01-18 The State University Of New York Telemetry capsule and process
US5500180A (en) 1992-09-30 1996-03-19 C. R. Bard, Inc. Method of making a distensible dilatation balloon using a block copolymer
US5414075A (en) 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
DE4480681C2 (de) 1994-02-17 2001-09-27 Scimed Life Systems Inc Verfahren zur Herstellung von Katheter-Ballonen und danach hergestellte orientierte Ballone
WO1995023619A1 (en) 1994-03-02 1995-09-08 Scimed Life Systems, Inc. Block copolymer elastomer catheter balloons
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
WO1997017098A1 (en) 1995-11-08 1997-05-15 Scimed Life Systems, Inc. Method of balloon formation by cold drawing/necking
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
DE19814730A1 (de) * 1998-04-02 1999-10-07 Basf Ag Verwendung von N-Vinyllacram oder N-Vinylamin haltigen Copolymeren als Matrix zur Herstellung von festen pharmazeutischen und kosmetischen Darreichungsformen
US6278018B1 (en) 1999-12-14 2001-08-21 Surmodics, Inc. Surface coating agents
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US7807750B2 (en) 2004-08-06 2010-10-05 Surmodics, Inc. Thermally-reactive polymers
CA2645324A1 (en) 2006-03-15 2007-09-27 Surmodics, Inc. Hydrophobic derivatives of natural biodegradable polysaccharides and uses thereof
JP5591103B2 (ja) * 2008-03-12 2014-09-17 アンジェスMg株式会社 薬剤溶出型カテーテル及びその製造方法
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US9757497B2 (en) * 2011-05-20 2017-09-12 Surmodics, Inc. Delivery of coated hydrophobic active agent particles

Also Published As

Publication number Publication date
JP2016523593A (ja) 2016-08-12
CA2912690A1 (en) 2014-11-20
CA2912690C (en) 2022-05-03
IL242545B (en) 2020-09-30
JP6469090B2 (ja) 2019-02-13
EP2996735A1 (en) 2016-03-23
WO2014186729A1 (en) 2014-11-20
EP2996735B1 (en) 2019-03-06

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