MX2013008647A - Metodo, composiciones y empaque para limpieza del intestino. - Google Patents
Metodo, composiciones y empaque para limpieza del intestino.Info
- Publication number
- MX2013008647A MX2013008647A MX2013008647A MX2013008647A MX2013008647A MX 2013008647 A MX2013008647 A MX 2013008647A MX 2013008647 A MX2013008647 A MX 2013008647A MX 2013008647 A MX2013008647 A MX 2013008647A MX 2013008647 A MX2013008647 A MX 2013008647A
- Authority
- MX
- Mexico
- Prior art keywords
- package
- composition
- bowel cleansing
- cleansing
- formulation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 235000019629 palatability Nutrition 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/009—Sachets, pouches characterised by the material or function of the envelope
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La presente invención provee una formulación de limpieza del colon altamente agradable al paladar que utiliza una solución básica de reabastecimiento de electrolito de bajo contenido de cloruro. Cuando es formulada con polietilenglicol y un alcohol de azúcar seleccionado, la formulación ofrece las ventajas de sabor agradable superior sin efectos secundarios concomitantes indeseables o una disminución en la eficacia de limpieza.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161462094P | 2011-01-28 | 2011-01-28 | |
PCT/US2011/064670 WO2012102799A2 (en) | 2011-01-28 | 2011-12-13 | Method, composition and package for bowel cleansing |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2013008647A true MX2013008647A (es) | 2013-11-04 |
MX346936B MX346936B (es) | 2017-04-05 |
Family
ID=45507871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013008647A MX346936B (es) | 2011-01-28 | 2011-12-13 | Metodo, composiciones y empaque para limpieza del intestino. |
Country Status (12)
Country | Link |
---|---|
US (7) | US8753618B2 (es) |
EP (1) | EP2667900B1 (es) |
JP (2) | JP5870119B2 (es) |
KR (1) | KR20140012980A (es) |
CN (2) | CN105963701A (es) |
AU (1) | AU2011356598B2 (es) |
BR (1) | BR112013019360A2 (es) |
CA (1) | CA2825808C (es) |
IL (1) | IL227655B (es) |
MX (1) | MX346936B (es) |
RU (1) | RU2651751C2 (es) |
WO (1) | WO2012102799A2 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012102799A2 (en) | 2011-01-28 | 2012-08-02 | Shaver William A | Method, composition and package for bowel cleansing |
TWI535461B (zh) | 2011-03-11 | 2016-06-01 | 諾金私人有限公司 | 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法 |
JP6240610B2 (ja) * | 2011-10-27 | 2017-11-29 | サリックス ファーマシューティカルズ,インコーポレイテッド | 電解質下剤 |
JP6301844B2 (ja) | 2012-02-09 | 2018-03-28 | ノグラ ファーマ リミテッド | 線維症の処置方法 |
MX359318B (es) | 2012-09-11 | 2018-09-25 | Norgine Bv | Composiciones que comprenden polietilenglicol y ascorbato. |
MX2015012109A (es) | 2013-03-15 | 2016-04-15 | Braintree Lab | Composicion farmaceutica oral de sales sulfato para comprimidos de uso dual y metodos para su uso. |
KR101423005B1 (ko) * | 2013-10-17 | 2014-07-28 | 강윤식 | 장 세정용 조성물 |
WO2015056897A1 (ko) * | 2013-10-17 | 2015-04-23 | 강윤식 | 장 세정용 조성물 |
KR101420315B1 (ko) | 2014-03-19 | 2014-07-17 | 남봉길 | 약학적 액제 조성물 |
US20160263152A1 (en) * | 2015-03-14 | 2016-09-15 | Gavis Pharmaceuticals | Bowel cleansing composition with improved taste |
US20180318234A1 (en) * | 2015-06-22 | 2018-11-08 | Ctc Bio, Inc. | Purgative composition for cleansing intestinal tract |
JP2018523694A (ja) | 2015-08-17 | 2018-08-23 | フェリング ベスローテン フェンノートシャップ | ピコスルファートおよびクエン酸マグネシウムを含む液体製剤 |
FR3049464B1 (fr) * | 2016-03-29 | 2021-08-06 | Marc Girard | Preparations coliques |
MA45584A (fr) * | 2016-07-06 | 2021-04-07 | Nogra Pharma Ltd | Formules contre le vieillissement. |
CN113825739A (zh) | 2019-02-08 | 2021-12-21 | 诺格拉制药有限公司 | 制备3-(4’-氨基苯基)-2-甲氧基丙酸及其类似物和中间体的方法 |
CN110433174A (zh) * | 2019-07-17 | 2019-11-12 | 华南理工大学 | 一种高依从性的复方聚乙二醇电解质散剂及其制备方法与应用 |
RU2709495C1 (ru) * | 2019-08-01 | 2019-12-18 | Общество с ограниченной ответственностью "Гелеспон" | Способ очищения кишечника и набор для его осуществления |
US11793876B2 (en) | 2019-10-18 | 2023-10-24 | L. Perrigo Company | Bulk polyethylene glycol compositions |
PL243659B1 (pl) * | 2020-10-30 | 2023-09-25 | Biogliko Spolka Z Ograniczona Odpowiedzialnoscia | Sucha kompozycja do rozpuszczania w wodzie |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0231356A1 (en) * | 1985-08-01 | 1987-08-12 | Braintree Laboratories, Inc. | Low-sodium laxative and lavage formulation |
IL86859A (en) | 1987-07-10 | 1991-12-15 | E Z Em Inc | Aqueous cathartic solution containing inorganic salts |
DE3889547T2 (de) | 1987-12-24 | 1994-11-17 | Borody Thomas J | Orthostatische waschlösungen. |
JPH0816061B2 (ja) | 1988-07-13 | 1996-02-21 | 森下ルセル株式会社 | 腸管洗浄液用組成物と腸管洗浄液 |
US5223264A (en) * | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
JP2721929B2 (ja) | 1990-01-30 | 1998-03-04 | 株式会社大塚製薬工場 | 腸管洗浄用組成物 |
JP3284620B2 (ja) | 1992-10-16 | 2002-05-20 | トヨタ自動車株式会社 | アンチスキッド制御装置 |
US5445805A (en) * | 1993-05-06 | 1995-08-29 | Church & Dwight Co., Inc. | Large potassium bicarbonate crystals and process for the preparation thereof |
RU2111741C1 (ru) * | 1994-10-27 | 1998-05-27 | Государственный научный центр колопроктологии Министерства здравоохранения и медицинской промышленности Российской Федерации | Вещество для общего промывания желудочно-кишечного тракта |
US6103268A (en) | 1995-11-03 | 2000-08-15 | Borody; Thomas Julius | Administering osmotic colonic evacuant containing a picosulfate |
US6444198B1 (en) * | 1999-02-22 | 2002-09-03 | Smithkline Beecham Corporation | Effervescent laxatives |
EA003064B1 (ru) * | 1999-02-22 | 2002-12-26 | Смитклайн Бичем Корпорейшн | Шипучие слабительные средства |
US6514537B1 (en) | 2000-06-02 | 2003-02-04 | Cumberland Swan Holdings, Inc. | Magnesium citrate solution |
ATE477790T1 (de) * | 2001-10-29 | 2010-09-15 | Ajinomoto Kk | Lösung zur darmreinigung |
AUPS088702A0 (en) | 2002-03-04 | 2002-03-28 | Borody, Thomas Julius | Electrolyte purgative |
US6946149B2 (en) | 2002-04-30 | 2005-09-20 | Braintree Laboratories, Inc. | Salt solution for colon cleansing |
US8361452B2 (en) | 2002-07-15 | 2013-01-29 | Halow George M | Bowel cleansing composition |
US7291324B2 (en) | 2002-10-22 | 2007-11-06 | Braintree Laboratories Inc. | Method of bowel cleansing |
GB0224909D0 (en) * | 2002-10-25 | 2002-12-04 | Norgine Europe Bv | Colon cleansing compositions |
US7332184B2 (en) | 2003-03-28 | 2008-02-19 | Queen's University At Kingston | Colonic cleansing composition and method |
JP2004323456A (ja) * | 2003-04-28 | 2004-11-18 | Shimizu Pharmaceutical Co Ltd | 腸管洗浄製剤 |
US7049319B2 (en) | 2003-09-23 | 2006-05-23 | Semaan Abboud | Colon cleansing composition and method |
US7687075B2 (en) | 2003-11-19 | 2010-03-30 | Salix Pharmaceuticals, Ltd. | Colonic purgative composition with soluble binding agent |
ES2247897B1 (es) * | 2003-12-18 | 2007-05-01 | Gat Formulation Gmbh | Tabletas con matriz polimerica emulsionada para emision controlada de gases y procedimiento para su fabricacion. |
GB0409104D0 (en) | 2004-04-23 | 2004-05-26 | Norgine Europe Bv | Compressed pharmaceutical compositions |
US20060051428A1 (en) * | 2004-09-03 | 2006-03-09 | Nelson Ayala | Aspartame and citrate flavored phosphate salt laxative |
CA2607250C (en) * | 2005-05-06 | 2012-11-06 | Salix Pharmaceuticals, Inc. | Polyethylene glycol colonic purgative composition |
JP4781071B2 (ja) | 2005-09-28 | 2011-09-28 | 三洋電機株式会社 | 電源装置と電池の冷却方法 |
US20070082061A1 (en) * | 2005-10-07 | 2007-04-12 | Nelson Ayala | Reduction of saltiness with sweeteners |
US20090258090A1 (en) * | 2008-04-11 | 2009-10-15 | Braintree Laboratories, Inc. | Colon cleansing solution |
KR101529702B1 (ko) | 2008-10-09 | 2015-06-17 | 가부시키가이샤 유야마 세이사쿠쇼 | 약제 포장유니트 및 이의 포장 제어방법 |
US8470983B2 (en) * | 2009-06-03 | 2013-06-25 | Aptalis Pharma Canada Inc. | L-sugar colon cleansing agent and uses thereof |
WO2012102799A2 (en) | 2011-01-28 | 2012-08-02 | Shaver William A | Method, composition and package for bowel cleansing |
-
2011
- 2011-12-13 WO PCT/US2011/064670 patent/WO2012102799A2/en active Application Filing
- 2011-12-13 EP EP11810932.1A patent/EP2667900B1/en active Active
- 2011-12-13 CN CN201610323588.3A patent/CN105963701A/zh active Pending
- 2011-12-13 CA CA2825808A patent/CA2825808C/en active Active
- 2011-12-13 MX MX2013008647A patent/MX346936B/es active IP Right Grant
- 2011-12-13 AU AU2011356598A patent/AU2011356598B2/en active Active
- 2011-12-13 CN CN201180068512.6A patent/CN103391790B/zh active Active
- 2011-12-13 RU RU2013138672A patent/RU2651751C2/ru active
- 2011-12-13 US US13/324,667 patent/US8753618B2/en active Active
- 2011-12-13 KR KR1020137022602A patent/KR20140012980A/ko not_active Application Discontinuation
- 2011-12-13 JP JP2013551968A patent/JP5870119B2/ja active Active
- 2011-12-13 BR BR112013019360A patent/BR112013019360A2/pt not_active IP Right Cessation
-
2013
- 2013-07-25 IL IL227655A patent/IL227655B/en active IP Right Grant
-
2014
- 2014-03-19 US US14/219,468 patent/US9211337B2/en active Active
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2015
- 2015-12-04 US US14/959,168 patent/US9566300B2/en active Active
-
2016
- 2016-01-08 JP JP2016002450A patent/JP2016117740A/ja active Pending
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2017
- 2017-01-09 US US15/402,002 patent/US10052295B2/en active Active
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2018
- 2018-08-20 US US16/105,504 patent/US10596135B2/en active Active - Reinstated
-
2020
- 2020-02-12 US US16/788,919 patent/US11241404B2/en active Active
-
2021
- 2021-12-22 US US17/559,580 patent/US20220233482A1/en not_active Abandoned
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