MX2011011503A - Inhibidores ciclicos de 11beta-hidroxiesteroide deshidrogenasa 1. - Google Patents
Inhibidores ciclicos de 11beta-hidroxiesteroide deshidrogenasa 1.Info
- Publication number
- MX2011011503A MX2011011503A MX2011011503A MX2011011503A MX2011011503A MX 2011011503 A MX2011011503 A MX 2011011503A MX 2011011503 A MX2011011503 A MX 2011011503A MX 2011011503 A MX2011011503 A MX 2011011503A MX 2011011503 A MX2011011503 A MX 2011011503A
- Authority
- MX
- Mexico
- Prior art keywords
- 11beta
- hydroxysteroid dehydrogenase
- cyclic inhibitors
- cortisol
- inhibition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Esta invención se refiere a nuevos compuestos de la Fórmula Ik, Im1, Im2, Im5, In1, ln2, In5, Io1, lo2, lo5, Ip1, Ip3, a sales farmacéuticamente aceptables de los mismos y a composiciones farmacéuticas de los mismos, que son útiles para el tratamiento terapéutico de enfermedades asociadas con la modulación o inhibición de 11ß-HSD1 en mamíferos; la invención también se refiere a composiciones farmacéuticas de los nuevos compuestos y métodos para su uso en la reducción o control de la producción de cortisol en una célula o la inhibición de la conversión de cortisona en cortisol en una célula.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2009/002653 WO2009134400A1 (en) | 2008-05-01 | 2009-04-30 | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| PCT/US2009/004261 WO2010011314A1 (en) | 2008-07-25 | 2009-07-23 | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
| PCT/US2010/033157 WO2010127237A2 (en) | 2009-04-30 | 2010-04-30 | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2011011503A true MX2011011503A (es) | 2011-11-18 |
Family
ID=45478607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2011011503A MX2011011503A (es) | 2009-04-30 | 2010-04-30 | Inhibidores ciclicos de 11beta-hidroxiesteroide deshidrogenasa 1. |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JP5784006B2 (es) |
| AP (1) | AP2011005948A0 (es) |
| CL (1) | CL2014001815A1 (es) |
| CO (1) | CO6501139A2 (es) |
| HK (1) | HK1169409A1 (es) |
| IL (1) | IL215249A (es) |
| MX (1) | MX2011011503A (es) |
| NZ (1) | NZ595473A (es) |
| PE (1) | PE20120794A1 (es) |
| TN (1) | TN2010000467A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010089303A1 (en) * | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009017671A1 (en) * | 2007-07-26 | 2009-02-05 | Vitae Pharmaceuticals, Inc. | Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
-
2010
- 2010-04-30 JP JP2012508772A patent/JP5784006B2/ja active Active
- 2010-04-30 AP AP2011005948A patent/AP2011005948A0/xx unknown
- 2010-04-30 NZ NZ595473A patent/NZ595473A/en not_active IP Right Cessation
- 2010-04-30 MX MX2011011503A patent/MX2011011503A/es active IP Right Grant
- 2010-04-30 PE PE2011001866A patent/PE20120794A1/es not_active Application Discontinuation
- 2010-10-14 TN TNP2010000467A patent/TN2010000467A1/fr unknown
-
2011
- 2011-09-20 IL IL215249A patent/IL215249A/en not_active IP Right Cessation
- 2011-10-05 CO CO11131281A patent/CO6501139A2/es not_active Application Discontinuation
-
2012
- 2012-10-16 HK HK12110197.6A patent/HK1169409A1/xx not_active IP Right Cessation
-
2014
- 2014-07-08 CL CL2014001815A patent/CL2014001815A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL215249A0 (en) | 2011-12-29 |
| HK1169409A1 (en) | 2013-01-25 |
| NZ595473A (en) | 2014-01-31 |
| PE20120794A1 (es) | 2012-07-26 |
| JP2012525440A (ja) | 2012-10-22 |
| IL215249A (en) | 2014-12-31 |
| JP5784006B2 (ja) | 2015-09-24 |
| CL2014001815A1 (es) | 2015-02-13 |
| CO6501139A2 (es) | 2012-08-15 |
| TN2010000467A1 (en) | 2012-05-24 |
| AP2011005948A0 (en) | 2011-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |