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MX2009006728A - Heterociclos de 5 miembros 2-sustituidos como inhibidores de scd. - Google Patents

Heterociclos de 5 miembros 2-sustituidos como inhibidores de scd.

Info

Publication number
MX2009006728A
MX2009006728A MX2009006728A MX2009006728A MX2009006728A MX 2009006728 A MX2009006728 A MX 2009006728A MX 2009006728 A MX2009006728 A MX 2009006728A MX 2009006728 A MX2009006728 A MX 2009006728A MX 2009006728 A MX2009006728 A MX 2009006728A
Authority
MX
Mexico
Prior art keywords
substituted
membered heterocycles
scd inhibitors
derivatives
stearoyl
Prior art date
Application number
MX2009006728A
Other languages
English (en)
Inventor
Rajender Kamboj
Vishnumurthy Kodumuru
Shaoyi Sun
Zaihui Zhang
Natalia Pokrovskaia
Natalie Dales
Jianmin Fu
Julia Fonarev
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009006728A publication Critical patent/MX2009006728A/es

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    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Orthopedic Medicine & Surgery (AREA)
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Abstract

La presente invención proporciona derivados heterocíclicos que modulan la actividad de la estearoil-CoA-desaturasa. También se abarcan métodos para utilizar estos derivados con el fin de modular la actividad de la estearoil-CoA-desaturasa, y composiciones farmacéuticas que comprenden tales derivados.
MX2009006728A 2006-12-20 2007-12-19 Heterociclos de 5 miembros 2-sustituidos como inhibidores de scd. MX2009006728A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87091906P 2006-12-20 2006-12-20
PCT/EP2007/064228 WO2008074835A1 (en) 2006-12-20 2007-12-19 2-substituted 5-membered heterocycles as scd inhibitors

Publications (1)

Publication Number Publication Date
MX2009006728A true MX2009006728A (es) 2009-09-09

Family

ID=39301480

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006728A MX2009006728A (es) 2006-12-20 2007-12-19 Heterociclos de 5 miembros 2-sustituidos como inhibidores de scd.

Country Status (11)

Country Link
US (1) US8258160B2 (es)
EP (1) EP2121671A1 (es)
JP (1) JP2010513403A (es)
KR (1) KR20090091337A (es)
CN (1) CN101595105B (es)
AU (1) AU2007336238A1 (es)
BR (1) BRPI0720452A2 (es)
CA (1) CA2672776A1 (es)
EA (1) EA200900820A1 (es)
MX (1) MX2009006728A (es)
WO (1) WO2008074835A1 (es)

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CA2672776A1 (en) 2008-06-26
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