MX2008002437A - Preparation of thioalkylamines using chlorosulfonic acid. - Google Patents
Preparation of thioalkylamines using chlorosulfonic acid.Info
- Publication number
- MX2008002437A MX2008002437A MX2008002437A MX2008002437A MX2008002437A MX 2008002437 A MX2008002437 A MX 2008002437A MX 2008002437 A MX2008002437 A MX 2008002437A MX 2008002437 A MX2008002437 A MX 2008002437A MX 2008002437 A MX2008002437 A MX 2008002437A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- formula
- preparation
- chlorosulfonic acid
- thioalkylamines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/24—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfuric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to a novel process for the preparation of compounds of the formula (I) by reacting in a first step amino alcohols of the formula (II) with chlorosulfonic acid to give sulfuric acid esters of the general formula (III) and by reacting these sulfuric acid esters in a second step with mercaptans or salts thereof of the general formula (IV): RSM in each formula, where applicable, R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, R<sup>5</sup>, R<sup>6</sup>, R, n and M have the meanings given in the description, in the presence of a diluent and in the presence of a base.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05018348 | 2005-08-24 | ||
PCT/EP2006/008061 WO2007022901A1 (en) | 2005-08-24 | 2006-08-16 | Preparation of thioalkylamines using chlorosulfonic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008002437A true MX2008002437A (en) | 2008-04-03 |
Family
ID=37101913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008002437A MX2008002437A (en) | 2005-08-24 | 2006-08-16 | Preparation of thioalkylamines using chlorosulfonic acid. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1981841A1 (en) |
KR (1) | KR20080036634A (en) |
BR (1) | BRPI0615132A2 (en) |
IL (1) | IL189465A0 (en) |
MX (1) | MX2008002437A (en) |
TW (1) | TW200722409A (en) |
WO (1) | WO2007022901A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201329025A (en) | 2011-11-01 | 2013-07-16 | Astex Therapeutics Ltd | Pharmaceutical compound |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6639109B1 (en) * | 1999-09-28 | 2003-10-28 | Nihon Nohyaku Co., Ltd. | Process for production of thioalkylamine derivatives |
KR100994169B1 (en) * | 2002-05-24 | 2010-11-15 | 바이엘 크롭사이언스 아게 | Method for preparing thioalkylamine derivative |
-
2006
- 2006-08-16 KR KR1020087005890A patent/KR20080036634A/en not_active Withdrawn
- 2006-08-16 MX MX2008002437A patent/MX2008002437A/en not_active Application Discontinuation
- 2006-08-16 WO PCT/EP2006/008061 patent/WO2007022901A1/en active Application Filing
- 2006-08-16 EP EP06776867A patent/EP1981841A1/en not_active Withdrawn
- 2006-08-16 BR BRPI0615132-9A patent/BRPI0615132A2/en not_active Application Discontinuation
- 2006-08-23 TW TW095130898A patent/TW200722409A/en unknown
-
2008
- 2008-02-12 IL IL189465A patent/IL189465A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007022901A1 (en) | 2007-03-01 |
TW200722409A (en) | 2007-06-16 |
IL189465A0 (en) | 2008-08-07 |
KR20080036634A (en) | 2008-04-28 |
EP1981841A1 (en) | 2008-10-22 |
BRPI0615132A2 (en) | 2011-05-03 |
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Legal Events
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FA | Abandonment or withdrawal |