[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

MX2007008826A - Methods and compositions for encapsulation of cells. - Google Patents

Methods and compositions for encapsulation of cells.

Info

Publication number
MX2007008826A
MX2007008826A MX2007008826A MX2007008826A MX2007008826A MX 2007008826 A MX2007008826 A MX 2007008826A MX 2007008826 A MX2007008826 A MX 2007008826A MX 2007008826 A MX2007008826 A MX 2007008826A MX 2007008826 A MX2007008826 A MX 2007008826A
Authority
MX
Mexico
Prior art keywords
compositions
methods
cells
present
encapsulation
Prior art date
Application number
MX2007008826A
Other languages
Spanish (es)
Inventor
Sam Stupp
John A Kessler
Original Assignee
Univ Northwestern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern filed Critical Univ Northwestern
Publication of MX2007008826A publication Critical patent/MX2007008826A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/25—Peptides having up to 20 amino acids in a defined sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to methods and compositions for altering (e.g., augmenting or stimulating) differentiation and growth of cells (e.g., neural progenitor cells and neurons). In particular, the present invention relates to compositions comprising one or more self-assembling peptide amphiphiles (e.g., in solution or that generate (e.g., self-assemble into) nanofibers (e.g., that are able to encapsulate cells and promote cellular differentiation (e.g., neurite development))) and methods of using the same. Compositions and methods of the present invention find use in research, clinical (e.g., therapeutic) and diagnostic settings.
MX2007008826A 2005-01-21 2006-01-23 Methods and compositions for encapsulation of cells. MX2007008826A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64566805P 2005-01-21 2005-01-21
PCT/US2006/002354 WO2006079036A2 (en) 2005-01-21 2006-01-23 Methods and compositions for encapsulation of cells

Publications (1)

Publication Number Publication Date
MX2007008826A true MX2007008826A (en) 2007-11-15

Family

ID=36692990

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007008826A MX2007008826A (en) 2005-01-21 2006-01-23 Methods and compositions for encapsulation of cells.

Country Status (10)

Country Link
US (1) US20060247165A1 (en)
EP (1) EP1838846A4 (en)
JP (1) JP2009500001A (en)
KR (1) KR20070100948A (en)
CN (1) CN101150954A (en)
AU (1) AU2006206194A1 (en)
CA (1) CA2590336A1 (en)
MX (1) MX2007008826A (en)
NZ (1) NZ555294A (en)
WO (1) WO2006079036A2 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002365162A1 (en) 2001-11-14 2003-07-09 Northwestern University Self-assembly and mineralization of peptide-amphiphile nanofibers
US7371719B2 (en) * 2002-02-15 2008-05-13 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
AU2003262760A1 (en) 2002-08-21 2004-03-11 Northwestern University Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom
US20050272662A1 (en) * 2002-09-23 2005-12-08 Stupp Samuel I Self-assembled peptide-amphiphiles & self-assembled peptide nanofiber networks presenting multiple signals
US7554021B2 (en) * 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
AU2003298647A1 (en) * 2002-11-14 2004-06-15 Claussen, Randal, C. Synthesis and self-assembly of abc triblock bola peptide
JP4837553B2 (en) * 2003-02-11 2011-12-14 ノースウエスタン ユニバーシティ Nanocrystal surface coating methods and materials and peptide amphiphile nanofiber deposits thereon
AU2004297211A1 (en) * 2003-12-05 2005-06-23 Northwestern University Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
AU2004296181A1 (en) 2003-12-05 2005-06-23 Northwestern University Self-assembling peptide amphiphiles and related methods for growth factor delivery
NZ560649A (en) * 2005-03-04 2011-03-31 Univ Northwestern Angiogenic heparin binding peptide amphiphiles, peptide amphiphiles, self-assembled composition and related methods of use
CU23526B6 (en) * 2006-10-03 2010-05-19 Ct Ingenieria Genetica Biotech METHOD FOR MORFOFUNCTIONAL RESTORATION OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY
JP2008184384A (en) * 2007-01-26 2008-08-14 Chiba Univ Axon-regeneration promoter and method for identifying candidate substance therefor
ITRM20070119A1 (en) * 2007-03-08 2008-09-09 Inbios S R L UDO DEL NGF FOR THE PREPARATION OF CELEBRATIONS FOR THE TREATMENT OF GLIOSI REACTIVE
US8076295B2 (en) * 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
AU2010236584A1 (en) 2009-04-13 2011-11-10 Northwestern University Novel peptide-based scaffolds for cartilage regeneration and methods for their use
DE102010001179A1 (en) * 2010-01-25 2011-07-28 Technische Universität Dresden, 01069 Use of hydrogels based on guluronsäure- and / or mannuronsäurehaltiger polysaccharides for the treatment of damage to the nervous system, for the promotion of nerve growth, for the treatment of neurodegenerative diseases and for the cultivation of neurons
GB201011602D0 (en) * 2010-07-09 2010-08-25 Univ London Pharmacy Delivery of hydrophilic peptides
US20130143805A1 (en) * 2010-08-13 2013-06-06 Georgetown University Ggf2 and methods of use
US8546338B2 (en) 2010-12-08 2013-10-01 Johnson & Johnson Consumer Companies, Inc. Self-assembling hydrogels based on dicephalic peptide amphiphiles
US8748569B2 (en) 2011-04-08 2014-06-10 Northwestern University Peptide amphiphiles and methods to electrostatically control bioactivity of the ikvav peptide epitope
KR101472476B1 (en) * 2011-11-14 2014-12-15 (주)노바셀테크놀로지 Novel peptide derivative capable of synthesizing collagen and use thereof
JP6263201B2 (en) * 2013-01-08 2018-01-17 ノバセル テクノロジー インコーポレイテッド Novel peptide having ability to synthesize collagen and use thereof
MY184796A (en) * 2013-12-11 2021-04-22 Sumitomo Chemical Co Method for manufacturing ciliary marginal zone-like structure
DE102015000363A1 (en) 2015-01-20 2016-07-21 Emc Microcollections Gmbh New modular functionalizable peptide hydrogels
JP7142284B2 (en) * 2017-06-06 2022-09-27 株式会社らいむ Nerve elongation promoter
WO2019195741A1 (en) * 2018-04-06 2019-10-10 Northwestern University Bdnf mimetic peptide amphiphiles
EP3569261B1 (en) * 2018-05-14 2024-04-03 Paul Hartmann AG Functional wound dressing
CN113777296A (en) * 2021-09-16 2021-12-10 复旦大学附属中山医院 Full-tissue immunofluorescence method and application
CN114601448B (en) * 2022-03-17 2024-08-09 中国科学院精密测量科学与技术创新研究院 Rapid magnetic resonance imaging method for visual quantitative evaluation of lung compliance

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US5130123A (en) * 1981-03-04 1992-07-14 The University Of Melbourne Dentifrice
US4930077A (en) * 1987-04-06 1990-05-29 Fan David P Information processing expert system for text analysis and predicting public opinion based information available to the public
GB8812214D0 (en) * 1988-05-24 1988-06-29 Hoffmann La Roche Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DE4026978A1 (en) * 1990-08-25 1992-02-27 Bayer Ag Coated substrates for electro=optical applications, etc.
ATE156344T1 (en) * 1991-04-25 1997-08-15 Univ Brown Res Found IMPLANTABLE, BIOCOMPATIBLE IMMUNE ISOLATOR CARRIER FOR DELIVERING SELECTED THERAPEUTIC PRODUCTS
US5670483A (en) * 1992-12-28 1997-09-23 Massachusetts Insititute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5955343A (en) * 1992-12-28 1999-09-21 Massachusetts Institute Of Technology Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
CA2228118A1 (en) * 1995-07-28 1997-02-13 Focal, Inc. Multiblock biodegradable hydrogels for use as controlled release agents for drugs delivery and tissue treatments agents
US5622699A (en) * 1995-09-11 1997-04-22 La Jolla Cancer Research Foundation Method of identifying molecules that home to a selected organ in vivo
US6051272A (en) * 1996-03-15 2000-04-18 The Board Of Trustees Of The University Of Illinois Method for synthesizing organoapatites on to surgical metal alloys
US5733868A (en) * 1996-04-16 1998-03-31 Depuy Orthopaedics, Inc. Poly(amino acid) adhesive tissue grafts
WO1997047695A1 (en) * 1996-06-12 1997-12-18 Hoechst Trespaphan Gmbh Transparent barrier coatings exhibiting reduced thin film interference
US6085206A (en) * 1996-06-20 2000-07-04 Microsoft Corporation Method and system for verifying accuracy of spelling and grammatical composition of a document
US5993541A (en) * 1996-07-31 1999-11-30 Geo Centers Inc Process for nucleation of ceramics and product thereof
US6096863A (en) * 1996-08-23 2000-08-01 Regents Of The University Of Minnesota Self-assembling amphiphiles for construction of peptide secondary structures
US6331406B1 (en) * 1997-03-31 2001-12-18 The John Hopkins University School Of Medicine Human enbryonic germ cell and methods of use
US6181909B1 (en) * 1997-07-22 2001-01-30 Educational Testing Service System and method for computer-based automatic essay scoring
US6269368B1 (en) * 1997-10-17 2001-07-31 Textwise Llc Information retrieval using dynamic evidence combination
ES2351082T3 (en) * 1997-12-02 2011-01-31 Artecel Sciences, Inc. DIFFERENTIATION OF ADIPOSE STORMAL CELLS IN OSTEOBLASTOS AND ITS USES.
GB9801061D0 (en) * 1998-01-20 1998-03-18 Univ Nottingham Patterning technique
SE519827C2 (en) * 1998-03-30 2003-04-15 Viranative Ab Nutritional medium containing methionine and its use
US7601685B2 (en) * 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
DE69906441T2 (en) * 1998-09-15 2004-04-08 Isotis B.V. Coating process for medical implants
US6114038A (en) * 1998-11-10 2000-09-05 Biocrystal Ltd. Functionalized nanocrystals and their use in detection systems
US6473730B1 (en) * 1999-04-12 2002-10-29 The Trustees Of Columbia University In The City Of New York Method and system for topical segmentation, segment significance and segment function
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
US6444723B1 (en) * 1999-11-10 2002-09-03 The United States Of America As Represented By The Secretary Of Commerce Crosslinked micellar gel composition
US20030077808A1 (en) * 2000-01-31 2003-04-24 Rosen Craig A. Nucleic acids, proteins, and antibodies
US6689165B2 (en) * 2000-03-31 2004-02-10 Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College Surface modifications for enhanced epithelialization
WO2001086489A2 (en) * 2000-05-11 2001-11-15 University Of Southern California Discourse parsing and summarization
JP4070605B2 (en) * 2000-10-19 2008-04-02 アイトゲノッシスシェ・テヒニッシュ・ホーホシューレ・ツューリヒ Block copolymers for multifunctional self-assembled systems
MXPA03006566A (en) * 2001-01-23 2004-10-15 Educational Testing Service Methods for automated essay analysis.
WO2002062969A2 (en) * 2001-02-06 2002-08-15 Massachusetts Institute Of Technology Cellular reprogramming in peptide hydrogel and uses thereof
US7449180B2 (en) * 2001-02-06 2008-11-11 John Kisiday Macroscopic scaffold containing amphiphilic peptides encapsulating cells
US7179784B2 (en) * 2001-07-10 2007-02-20 Massachusetts Institute Of Technology Surfactant peptide nanostructures, and uses thereof
AU2002365162A1 (en) 2001-11-14 2003-07-09 Northwestern University Self-assembly and mineralization of peptide-amphiphile nanofibers
US7371719B2 (en) 2002-02-15 2008-05-13 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
WO2003084980A2 (en) 2002-04-02 2003-10-16 Northwestern University Peptide amphiphile solutions and self assembled peptide nanofiber networks
WO2003090255A2 (en) 2002-04-18 2003-10-30 Northwestern University Encapsulation of nanotubes via self-assembled nanostructures
JP2005185101A (en) * 2002-05-30 2005-07-14 National Institute Of Agrobiological Sciences VEGETABLE FULL-LENGTH cDNA AND UTILIZATION THEREOF
AU2003279912A1 (en) 2002-06-27 2004-01-19 Northwestern University Peptide rod amphiphiles and self-assembly of same
AU2003262760A1 (en) * 2002-08-21 2004-03-11 Northwestern University Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom
US20050272662A1 (en) * 2002-09-23 2005-12-08 Stupp Samuel I Self-assembled peptide-amphiphiles & self-assembled peptide nanofiber networks presenting multiple signals
US7135027B2 (en) * 2002-10-04 2006-11-14 Baxter International, Inc. Devices and methods for mixing and extruding medically useful compositions
WO2005003292A2 (en) 2002-11-12 2005-01-13 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
US7554021B2 (en) * 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
AU2003298647A1 (en) * 2002-11-14 2004-06-15 Claussen, Randal, C. Synthesis and self-assembly of abc triblock bola peptide
JP4837553B2 (en) 2003-02-11 2011-12-14 ノースウエスタン ユニバーシティ Nanocrystal surface coating methods and materials and peptide amphiphile nanofiber deposits thereon
GB0303362D0 (en) * 2003-02-13 2003-03-19 Enact Pharma Plc Tissue regeneration
AU2004296181A1 (en) * 2003-12-05 2005-06-23 Northwestern University Self-assembling peptide amphiphiles and related methods for growth factor delivery
AU2004297211A1 (en) 2003-12-05 2005-06-23 Northwestern University Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
US20050214257A1 (en) * 2003-12-23 2005-09-29 Northwestern University Compositions and methods for controlling stem cell and tumor cell differentiation, growth, and formation
WO2005094862A1 (en) * 2004-03-23 2005-10-13 Lifeline Nutraceuticals Corporation Compositions and method for alleviating inflammation and oxidative stress in a mammal
US20060188555A1 (en) * 2005-01-21 2006-08-24 Micheal Cormier Therapeutic peptide formulations with improved stability
NZ560649A (en) * 2005-03-04 2011-03-31 Univ Northwestern Angiogenic heparin binding peptide amphiphiles, peptide amphiphiles, self-assembled composition and related methods of use
US8114834B2 (en) * 2006-11-09 2012-02-14 Northwestern University Self-assembling peptide amphiphiles
US8114835B2 (en) * 2006-11-09 2012-02-14 Northwestern University Self-assembling peptide amphiphiles for tissue engineering
US8772228B2 (en) * 2007-02-14 2014-07-08 Northwestern University Aligned nanofibers and related methods of use
US8076295B2 (en) * 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
US20090098652A1 (en) * 2007-08-17 2009-04-16 Northwestern University Self assembling peptide systems and methods

Also Published As

Publication number Publication date
AU2006206194A1 (en) 2006-07-27
WO2006079036A2 (en) 2006-07-27
EP1838846A4 (en) 2008-12-10
JP2009500001A (en) 2009-01-08
EP1838846A2 (en) 2007-10-03
US20060247165A1 (en) 2006-11-02
CN101150954A (en) 2008-03-26
KR20070100948A (en) 2007-10-15
WO2006079036A3 (en) 2007-11-22
CA2590336A1 (en) 2006-07-27
NZ555294A (en) 2010-07-30

Similar Documents

Publication Publication Date Title
MX2007008826A (en) Methods and compositions for encapsulation of cells.
AU2017368136B2 (en) Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes
MX2012001194A (en) Antigenic tau peptides and uses thereof.
WO2009135190A3 (en) Therapeutic calcium phosphate particles and methods of making and using same
WO2009135855A3 (en) Encapsulation of biologically active agents
GB2472964A (en) Vectors for delivery of light-sensitive proteins and methods of use
JP2016516023A5 (en)
DE602006017071D1 (en) COMPOSITIONS AND METHODS OF TREATING HEART DISEASES
EA201171279A1 (en) MANUFACTURE OF INCAPSULATED NANOPARTICLES WITH HIGH VOLUME RATES
HK1145070A1 (en) Therapeutic use of a growth factor, metrnl
WO2011084808A3 (en) Bifunctional polypeptide compositions and methods for treatment of metabolic and cardiovascular diseases
WO2009135853A3 (en) Encapsulation of biologically active agents
EP2479277A3 (en) Compositions and methods of use for MGD-CSF in disease treatment
WO2010085039A2 (en) Noggin-derived peptide and use thereof
WO2007024441A3 (en) Compositions of cells enriched for combinations of various stem and progenitor cell populations, methods of use thereof and methods of private banking thereof
UA100127C2 (en) Peptide cdh3 and drug containing it
MX344815B (en) Method for purifying human granulocyte-colony stimulating factor from recombinant e. coli.
ATE409741T1 (en) NERVE GROWTH FACTOR SECRETING HUMAN THERAPEUTIC CELLS
HRP20050585A2 (en) Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof
EA200702523A1 (en) APPLICATION OF ERYTHROPOIETHIN IN LOW DOSAGE FOR STIMULATION OF ENDOTHELIAL CELLS PRECONDENTS, AND ALSO FOR REGENERATION OF ORGANS AND SLOWING PROGRESSION OF DAMAGES OF FINAL ORGANS
CL2008001211A1 (en) Compounds derived from silylated benzotriazolylphenol; Preparation process; pharmaceutical composition; and use in the treatment of unwanted skin conditions such as actinic keratosis, solar urticaria, and solar erythema.
WO2006117686A3 (en) Compounds that stimulate glucose utilization and methods of use
MX2020010807A (en) Growth promoting peptides and uses thereof.
MX2011007462A (en) Hylauronic acid containing compositions for treatment of wounds, scars, post-surgical adhesion formation.
WO2010119997A1 (en) Peptide having activity of transforming growth factor and production method therefor

Legal Events

Date Code Title Description
FA Abandonment or withdrawal