MA50256A - Composés de pyrazolopyrimidinone et leurs utilisations - Google Patents
Composés de pyrazolopyrimidinone et leurs utilisationsInfo
- Publication number
- MA50256A MA50256A MA050256A MA50256A MA50256A MA 50256 A MA50256 A MA 50256A MA 050256 A MA050256 A MA 050256A MA 50256 A MA50256 A MA 50256A MA 50256 A MA50256 A MA 50256A
- Authority
- MA
- Morocco
- Prior art keywords
- pyrazolopyrimidinone compounds
- pyrazolopyrimidinone
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762559482P | 2017-09-15 | 2017-09-15 | |
| US201862633248P | 2018-02-21 | 2018-02-21 | |
| US201862687769P | 2018-06-20 | 2018-06-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA50256A true MA50256A (fr) | 2020-07-22 |
Family
ID=65723108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA050256A MA50256A (fr) | 2017-09-15 | 2018-09-14 | Composés de pyrazolopyrimidinone et leurs utilisations |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10738056B2 (fr) |
| EP (1) | EP3681888A4 (fr) |
| JP (1) | JP2020533376A (fr) |
| KR (1) | KR20200032751A (fr) |
| CN (1) | CN111212839A (fr) |
| AU (1) | AU2018331456B2 (fr) |
| BR (1) | BR112020003676A2 (fr) |
| CA (1) | CA3075751A1 (fr) |
| CL (1) | CL2020000544A1 (fr) |
| CO (1) | CO2020002107A2 (fr) |
| CR (1) | CR20200114A (fr) |
| DO (1) | DOP2020000051A (fr) |
| EC (1) | ECSP20018586A (fr) |
| IL (1) | IL273236A (fr) |
| JO (1) | JOP20200055A1 (fr) |
| MA (1) | MA50256A (fr) |
| MX (1) | MX2020002869A (fr) |
| PE (1) | PE20210340A1 (fr) |
| PH (1) | PH12020500500A1 (fr) |
| SG (1) | SG11202002218VA (fr) |
| TW (1) | TW201920185A (fr) |
| WO (1) | WO2019055750A1 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018045071A1 (fr) | 2016-08-31 | 2018-03-08 | Agios Pharmaceuticals, Inc. | Inhibiteurs de processus métaboliques cellulaires |
| JOP20170192A1 (ar) | 2016-12-01 | 2019-01-30 | Takeda Pharmaceuticals Co | داي نوكليوتيد حلقي |
| CA3082351A1 (fr) | 2017-11-10 | 2019-05-16 | Takeda Pharmaceutical Company Limited | Composes modulateurs de sting, et procedes de fabrication et d'utilisation |
| US11203610B2 (en) | 2017-12-20 | 2021-12-21 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| KR102492187B1 (ko) | 2017-12-20 | 2023-01-27 | 인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. | Sting 어댑터 단백질을 활성화하는 포스포네이트 결합을 가진 3'3' 사이클릭 다이뉴클레오티드 |
| TWI833744B (zh) | 2018-04-06 | 2024-03-01 | 捷克科學院有機化學與生物化學研究所 | 3'3'-環二核苷酸 |
| TWI818007B (zh) | 2018-04-06 | 2023-10-11 | 捷克科學院有機化學與生物化學研究所 | 2'3'-環二核苷酸 |
| MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
| CA3151850A1 (fr) * | 2019-08-21 | 2021-02-25 | The Scripps Research Institute | Agonistes bicycliques du simulateur de genes d'interferon (sting) |
| CN110724143B (zh) * | 2019-10-09 | 2021-03-23 | 清华大学 | 一种靶向btk蛋白降解化合物的制备及其在治疗自身免疫系统疾病与肿瘤中的应用 |
| CN110627725B (zh) * | 2019-10-14 | 2022-10-18 | 遵义医科大学 | 一种4-取代5-二氟甲基-3-硝基-1h-吡唑类化合物及其制备方法与应用 |
| US11512097B2 (en) | 2019-11-25 | 2022-11-29 | Amgen Inc. | Heterocyclic compounds as Delta-5 desaturase inhibitors and methods of use |
| CN113248491B (zh) * | 2020-02-11 | 2022-02-25 | 中国科学院上海药物研究所 | 一类取代的吲哚脲衍生物、合成方法及其用途 |
| WO2021233851A1 (fr) * | 2020-05-20 | 2021-11-25 | F. Hoffmann-La Roche Ag | Nouveaux dérivés de malonitrile |
| EP4153577A1 (fr) * | 2020-05-20 | 2023-03-29 | F. Hoffmann-La Roche AG | Nouveaux dérivés de malonitrile |
| CN115667265A (zh) * | 2020-05-20 | 2023-01-31 | 豪夫迈·罗氏有限公司 | Cgas抑制三唑并嘧啶酮衍生物 |
| EP4240488A1 (fr) | 2020-11-09 | 2023-09-13 | Takeda Pharmaceutical Company Limited | Conjugués anticorps-médicament |
| CN114644633A (zh) * | 2020-12-18 | 2022-06-21 | 北京诺诚健华医药科技有限公司 | 杂环类jak抑制剂 |
| EP4267571A1 (fr) * | 2020-12-22 | 2023-11-01 | Novartis AG | Dérivés de pyrrolo[3,2-b]pyridine utiles dans le traitement d'états associés à la cgas |
| US20240252598A1 (en) * | 2021-04-13 | 2024-08-01 | University Of Washington | Designed constitutively active cyclic gmp-amp synthase as a genetically encoded stimulant of interferons |
| WO2024137607A1 (fr) * | 2022-12-20 | 2024-06-27 | Ventus Therapeutics U.S., Inc. | Dérivés de thiadiazole en tant qu'inhibiteurs de la gmp-amp synthase cyclique et leurs utilisations |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JPS625362A (ja) | 1985-06-30 | 1987-01-12 | 菊地 真 | ハイパ−サ−ミア用加温装置 |
| JPH02131235A (ja) | 1988-11-12 | 1990-05-21 | Fuji Photo Film Co Ltd | 新規なカプラーを含有するハロゲン化銀写真感光材料 |
| US5420128A (en) | 1990-10-09 | 1995-05-30 | Otsuka Pharmaceutical Co., Ltd. | Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor |
| AU651986B2 (en) * | 1991-04-22 | 1994-08-11 | Otsuka Pharmaceutical Factory, Inc. | Pyrazolo{1,5-a}pyrimidine derivative and anti-inflammatory containing the same |
| AU707530B2 (en) | 1995-09-28 | 1999-07-15 | Otsuka Pharmaceutical Factory, Inc. | Analgesic composition |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| FR2746309B1 (fr) | 1996-03-22 | 1998-04-17 | Oreal | Composition de teinture des fibres keratiniques contenant des pyrazolopyrimidineoxo ; leur utilisation pour la teinture comme coupleurs, procedes de teinture |
| US6060478A (en) | 1996-07-24 | 2000-05-09 | Dupont Pharmaceuticals | Azolo triazines and pyrimidines |
| EP1019501A1 (fr) * | 1997-03-14 | 2000-07-19 | Otsuka Pharmaceutical Co., Ltd. | Nouveau derive de la pyrimidine |
| JP3625362B2 (ja) | 1997-09-08 | 2005-03-02 | コニカミノルタホールディングス株式会社 | 感熱転写記録材料及び感熱転写記録方法 |
| US6245759B1 (en) | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| WO2004001058A2 (fr) | 2001-05-04 | 2003-12-31 | Paratek Pharmaceuticals, Inc. | Composes modulateurs de facteurs de transcription et procedes d'utilisation |
| US7405235B2 (en) | 2001-05-04 | 2008-07-29 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| US7449488B2 (en) | 2002-06-04 | 2008-11-11 | Schering Corporation | Pyrazolopyrimidines as protein kinase inhibitors |
| CN1671710A (zh) | 2002-06-04 | 2005-09-21 | 新创世纪药品公司 | 用作抗病毒药物的吡唑并[1,5－a]嘧啶化合物 |
| WO2004041209A2 (fr) | 2002-11-01 | 2004-05-21 | Paratek Pharmaceuticals, Inc. | Composés modulant le facteur de transcription et méthodes d'utilisation de ces derniers |
| JP2005008581A (ja) * | 2003-06-20 | 2005-01-13 | Kissei Pharmaceut Co Ltd | 新規なピラゾロ［１，５−ａ］ピリミジン誘導体、それを含有する医薬組成物およびそれらの用途 |
| DE10356579A1 (de) | 2003-12-04 | 2005-07-07 | Merck Patent Gmbh | Aminderivate |
| JP2008504233A (ja) | 2004-04-23 | 2008-02-14 | パラテック ファーマシューティカルズ インコーポレイテッド | 転写因子調節化合物およびその使用法 |
| SI2188291T1 (sl) | 2007-08-14 | 2013-01-31 | Bayer Intellectual Property Gmbh | Zliti biciklični pirimidini |
| WO2009039323A1 (fr) | 2007-09-19 | 2009-03-26 | Smithkline Beecham Corporation | Inhibiteurs de la prolyl hydroxylase |
| WO2009071705A1 (fr) * | 2007-12-07 | 2009-06-11 | Galapagos Nv | Nouveaux composés utiles pour le traitement de maladies dégénératives et inflammatoires |
| CA2708300A1 (fr) * | 2007-12-11 | 2009-06-18 | Schering Corporation | Modulateurs de gamma secretase |
| JP5637859B2 (ja) | 2007-12-13 | 2014-12-10 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 嚢胞性線維症膜コンダクタンスレギュレーターのモジュレーター |
| EP2219646A4 (fr) | 2007-12-21 | 2010-12-22 | Univ Rochester | Procédé permettant de modifier la durée de vie d'organismes eucaryotes |
| CN101906105B (zh) | 2009-06-08 | 2013-01-16 | 河北医科大学 | 吡唑并[1，5-a]嘧啶酮衍生物及其药物组合物以及其用途 |
| CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
| EP3053924A1 (fr) * | 2010-08-12 | 2016-08-10 | Boehringer Ingelheim International Gmbh | Dérivés de 6-cycloalkyl-1,5-dihydro-pyrazolo [3,4-d] pyrimidin-4-un et leur utilisation en tant qu'inhibiteurs de la pde9a |
| JP2013538838A (ja) | 2010-09-27 | 2013-10-17 | プロクシマゲン リミテッド | ７−ヒドロキシ−ピラゾロ［１，５−ａ］ピリミジン化合物およびｃｃｒ２レセプターアンタゴニストとしてのその使用 |
| WO2012149157A2 (fr) * | 2011-04-26 | 2012-11-01 | Bioenergenix | Composés hétérocycliques pour l'inhibition de pask |
| EP2518070A1 (fr) * | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Dérivés de pyrrolotriazinon en tant qu'inhibiteurs PI3K |
| EP2861232A1 (fr) | 2012-05-23 | 2015-04-22 | Savira Pharmaceuticals GmbH | Dérivés de 7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine qui sont utiles dans le traitement, l'amélioration ou la prévention d'une maladie virale |
| US9434745B2 (en) | 2012-05-23 | 2016-09-06 | Savira Pharmaceuticals Gmbh | 7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease |
| RU2015107803A (ru) | 2012-08-06 | 2016-09-27 | Савира Фармасьютикалз Гмбх | Производные дигидроксипиримидинкарбоновой кислоты и их применение в лечении, облегчении или предотвращении вирусного заболевания |
| CA2904760A1 (fr) | 2013-03-13 | 2014-09-18 | Genentech, Inc. | Composes pyrazolo et leurs utilisations |
| CN105611933B (zh) * | 2013-09-05 | 2019-01-25 | 基因泰克公司 | 抗增生性化合物 |
| WO2015135094A1 (fr) | 2014-03-13 | 2015-09-17 | Genentech, Inc. | Composés thérapeutiques et leurs utilisations |
| EP3148986A4 (fr) | 2014-05-27 | 2018-01-10 | Navigen, Inc. | Inhibiteurrs d'arf6 et leurs méthodes de synthèse et d'utilisation |
| CN106146508A (zh) * | 2015-03-19 | 2016-11-23 | 浙江导明医药科技有限公司 | 优化的联合用药及其治疗癌症和自身免疫疾病的用途 |
| JP6754772B2 (ja) * | 2015-10-23 | 2020-09-16 | 武田薬品工業株式会社 | 複素環化合物 |
| US11414385B2 (en) | 2015-12-21 | 2022-08-16 | The University Of Chicago | Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases |
| JP7051703B2 (ja) | 2016-04-15 | 2022-04-11 | バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ピラゾロピリミジン誘導体 |
| US20200317674A1 (en) | 2016-06-03 | 2020-10-08 | An2H Discovery Limited | Pyrazolopyrimidine derivatives and the compositions and methods of treatment regarding the same |
| WO2018039972A1 (fr) | 2016-08-31 | 2018-03-08 | Agios Pharmaceuticals, Inc. | Inhibiteurs de processus métaboliques cellulaires |
| WO2018045071A1 (fr) | 2016-08-31 | 2018-03-08 | Agios Pharmaceuticals, Inc. | Inhibiteurs de processus métaboliques cellulaires |
| WO2018229683A1 (fr) | 2017-06-15 | 2018-12-20 | Novartis Ag | Composés 5,6-fusionnés-bicycliques et compositions pour le traitement de maladies parasitaires |
| JP2020531519A (ja) * | 2017-08-21 | 2020-11-05 | ナビゲン，インコーポレーテッド | Ａｒｆ６阻害剤及び関連する方法 |
-
2018
- 2018-09-14 TW TW107132537A patent/TW201920185A/zh unknown
- 2018-09-14 KR KR1020207007178A patent/KR20200032751A/ko not_active Application Discontinuation
- 2018-09-14 JP JP2020515108A patent/JP2020533376A/ja not_active Withdrawn
- 2018-09-14 MX MX2020002869A patent/MX2020002869A/es unknown
- 2018-09-14 CR CR20200114A patent/CR20200114A/es unknown
- 2018-09-14 CN CN201880059704.2A patent/CN111212839A/zh active Pending
- 2018-09-14 SG SG11202002218VA patent/SG11202002218VA/en unknown
- 2018-09-14 JO JOP/2020/0055A patent/JOP20200055A1/ar unknown
- 2018-09-14 MA MA050256A patent/MA50256A/fr unknown
- 2018-09-14 AU AU2018331456A patent/AU2018331456B2/en not_active Ceased
- 2018-09-14 WO PCT/US2018/051014 patent/WO2019055750A1/fr active Application Filing
- 2018-09-14 US US16/131,221 patent/US10738056B2/en active Active
- 2018-09-14 CA CA3075751A patent/CA3075751A1/fr not_active Abandoned
- 2018-09-14 EP EP18857356.2A patent/EP3681888A4/fr not_active Withdrawn
- 2018-09-14 PE PE2020000341A patent/PE20210340A1/es unknown
- 2018-09-14 BR BR112020003676-5A patent/BR112020003676A2/pt not_active Application Discontinuation
-
2020
- 2020-02-27 CO CONC2020/0002107A patent/CO2020002107A2/es unknown
- 2020-03-02 DO DO2020000051A patent/DOP2020000051A/es unknown
- 2020-03-04 CL CL2020000544A patent/CL2020000544A1/es unknown
- 2020-03-11 IL IL273236A patent/IL273236A/en unknown
- 2020-03-12 PH PH12020500500A patent/PH12020500500A1/en unknown
- 2020-03-13 EC ECSENADI202018586A patent/ECSP20018586A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JOP20200055A1 (ar) | 2020-03-10 |
| EP3681888A4 (fr) | 2021-07-07 |
| CN111212839A (zh) | 2020-05-29 |
| US20190119285A1 (en) | 2019-04-25 |
| SG11202002218VA (en) | 2020-04-29 |
| AU2018331456A1 (en) | 2020-03-05 |
| TW201920185A (zh) | 2019-06-01 |
| DOP2020000051A (es) | 2020-08-15 |
| ECSP20018586A (es) | 2020-06-30 |
| BR112020003676A2 (pt) | 2020-09-01 |
| AU2018331456B2 (en) | 2020-10-08 |
| MX2020002869A (es) | 2020-07-24 |
| IL273236A (en) | 2020-04-30 |
| EP3681888A1 (fr) | 2020-07-22 |
| WO2019055750A1 (fr) | 2019-03-21 |
| PE20210340A1 (es) | 2021-02-22 |
| PH12020500500A1 (en) | 2021-03-01 |
| CA3075751A1 (fr) | 2019-03-21 |
| CL2020000544A1 (es) | 2020-10-02 |
| CO2020002107A2 (es) | 2020-05-29 |
| US10738056B2 (en) | 2020-08-11 |
| JP2020533376A (ja) | 2020-11-19 |
| CR20200114A (es) | 2020-06-01 |
| KR20200032751A (ko) | 2020-03-26 |
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| MA53184A (fr) | Anticorps anti-ox40 et leurs utilisations | |
| MA45943A (fr) | Compositions ignifuges et leurs utilisations | |
| MA41460A (fr) | Agents de liaison à la tnfrsf et leurs utilisations | |
| MA43821A (fr) | Pyrimidines et variantes de celles-ci, et leurs utilisations | |
| MA46471A (fr) | Protéines actriib à variant et leurs utilisations | |
| MA45125A (fr) | Anticorps anti-alpha-synucléine et leurs utilisations | |
| MA43567A (fr) | Anticorps pacap et leurs utilisations | |
| MA52365A (fr) | Composés et leurs utilisations | |
| MA55044A (fr) | Hétéromultimères alk4:actriib et leurs utilisations | |
| MA49886A (fr) | Anticorps anti-par2 et leurs utilisations | |
| MA45857A (fr) | Composés et compositions, et utilisations associées | |
| MA44262A (fr) | Bioconjugués et utilisations de ceux-ci |