MA43591A - Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement - Google Patents
Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitementInfo
- Publication number
- MA43591A MA43591A MA043591A MA43591A MA43591A MA 43591 A MA43591 A MA 43591A MA 043591 A MA043591 A MA 043591A MA 43591 A MA43591 A MA 43591A MA 43591 A MA43591 A MA 43591A
- Authority
- MA
- Morocco
- Prior art keywords
- treatment
- methods
- subject requiring
- inhibiting fibrosis
- fibrosis
- Prior art date
Links
- 206010016654 Fibrosis Diseases 0.000 title 1
- 230000004761 fibrosis Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662275025P | 2016-01-05 | 2016-01-05 | |
US201662407979P | 2016-10-13 | 2016-10-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA43591A true MA43591A (fr) | 2021-05-26 |
Family
ID=59236184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA043591A MA43591A (fr) | 2016-01-05 | 2017-01-05 | Méthodes d'inhibition d'une fibrose chez un sujet ayant besoin d'un tel traitement |
Country Status (21)
Country | Link |
---|---|
US (2) | US10736960B2 (fr) |
EP (1) | EP3400012A4 (fr) |
JP (3) | JP6682653B2 (fr) |
KR (4) | KR102564616B1 (fr) |
CN (3) | CN117503923A (fr) |
AU (4) | AU2017205453B2 (fr) |
BR (1) | BR112018013723A2 (fr) |
CA (2) | CA3185172A1 (fr) |
CL (3) | CL2018001817A1 (fr) |
EA (1) | EA201891570A1 (fr) |
GE (1) | GEP20217290B (fr) |
IL (2) | IL294411A (fr) |
MA (1) | MA43591A (fr) |
MX (3) | MX2018008331A (fr) |
MY (1) | MY194810A (fr) |
NZ (1) | NZ744629A (fr) |
PH (1) | PH12018501435A1 (fr) |
SG (2) | SG10202001580SA (fr) |
UA (1) | UA127339C2 (fr) |
WO (1) | WO2017120344A1 (fr) |
ZA (1) | ZA201805238B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101141544B1 (ko) | 2009-03-13 | 2012-05-03 | 한국과학기술원 | 에스아이알엔에이 다중 접합체 및 이의 제조방법 |
MX2017016088A (es) | 2015-06-15 | 2018-04-11 | Mpeg La Llc | Oligonucleotidos multi-conjugados definidos. |
KR102564616B1 (ko) | 2016-01-05 | 2023-08-08 | 유니버시티 오브 레스터 | 필요로 하는 대상체에서 섬유증의 억제 방법 |
JOP20170170B1 (ar) | 2016-08-31 | 2022-09-15 | Omeros Corp | صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق |
JOP20190068A1 (ar) * | 2016-10-13 | 2019-04-01 | Omeros Corp | طرق لتقليل البول البروتيني في خاضع بشري يعاني من الاعتلال الكلوي a الناتج عن الجلوبيولين المناعي |
EP3795585A4 (fr) * | 2018-05-16 | 2022-03-16 | Genome and Company | Composition pharmaceutique destinée à prévenir ou traiter le cancer comprenant un inhibiteur de lrit2 en tant que principe actif |
WO2020186256A1 (fr) * | 2019-03-14 | 2020-09-17 | Aravive Inc | Procédés de traitement d'une néphropathie à immunoglobuline a (igan) à l'aide de récepteurs leurres axl |
WO2021026476A1 (fr) * | 2019-08-08 | 2021-02-11 | Mpeg La, L.L.C. | Ciblage du complément avec des oligonucléotides multimères |
JP2023503611A (ja) * | 2019-11-26 | 2023-01-31 | オメロス コーポレーション | 造血幹細胞移植に関連する特発性肺炎症候群(ips)および/または毛細血管漏出症候群(cls)および/または生着症候群(es)および/または体液過剰(fo)を治療および/または予防するための方法 |
WO2021113698A1 (fr) | 2019-12-04 | 2021-06-10 | Omeros Corporation | Inhibiteurs de masp-2 et procédés d'utilisation |
CA3159167A1 (fr) | 2019-12-04 | 2021-06-10 | Neil S. Cutshall | Inhibiteurs de masp-2 et procedes d'utilisation |
IL293588A (en) | 2019-12-04 | 2022-08-01 | Omeros Corp | 2-masp inhibitor compounds, preparations containing them and their uses |
US11807641B2 (en) | 2019-12-04 | 2023-11-07 | Omeros Corporation | MASP-2 inhibitors and methods of use |
CN113272013A (zh) | 2019-12-17 | 2021-08-17 | 奇努克医疗公司 | 用阿曲生坦治疗IgA肾病的方法 |
CN111419860A (zh) * | 2020-03-19 | 2020-07-17 | 长春市儿童医院 | 一种肾小球分叶状肾病造模方法 |
US20220110894A1 (en) * | 2020-10-13 | 2022-04-14 | Accubit LLC - Biotechnology | Methods of Treating IgA Nephropathy with Thiol-Containing Molecules |
CN116615544A (zh) * | 2021-12-10 | 2023-08-18 | 舒泰神(北京)生物制药股份有限公司 | 特异性识别masp2的抗体及其应用 |
AU2022405100A1 (en) | 2021-12-10 | 2024-07-25 | Omeros Corporation | Therapeutic antibodies that bind to the serine protease domain of masp-2 and uses thereof |
WO2023225163A1 (fr) * | 2022-05-19 | 2023-11-23 | Chinook Therapeutics, Inc. | Méthodes de traitement de la glomérulosclérose segmentaire et focale avec de l'atrasentan |
US20240228499A1 (en) | 2022-11-30 | 2024-07-11 | Omeros Corporation | Masp-2 inhibitors and methods of use |
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US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5453566A (en) | 1986-03-28 | 1995-09-26 | Calgene, Inc. | Antisense regulation of gene expression in plant/cells |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
RO114469B1 (ro) | 1987-12-15 | 1999-04-30 | Gene Shears Pty Ltd | Compus oligoribonucleotidic, procedeu de preparare si metoda de inactivare |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
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US5211657A (en) | 1988-11-07 | 1993-05-18 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Laminin a chain deduced amino acid sequence, expression vectors and active synthetic peptides |
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US5549910A (en) | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
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HUE024996T2 (en) | 2003-05-12 | 2016-01-28 | Helion Biotech Aps | Anti-MASP-2 antibodies |
US8840893B2 (en) | 2004-06-10 | 2014-09-23 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
US20140056873A1 (en) * | 2004-06-10 | 2014-02-27 | University Of Leicester | Methods for Treating Conditions Associated with MASP-2 Dependent Complement Activation |
US7919094B2 (en) | 2004-06-10 | 2011-04-05 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
US7626730B2 (en) * | 2006-03-31 | 2009-12-01 | Eastman Kodak Company | Method of making a multilevel halftone screen |
BR112012008970A2 (pt) | 2009-10-16 | 2019-12-10 | Omeros Corp | uso de uma composição, e, composição |
WO2012100262A1 (fr) | 2011-01-21 | 2012-07-26 | Fibrogen, Inc. | Méthode thérapeutique utilisant un anticorps anti-ctgf |
US9644035B2 (en) * | 2011-04-08 | 2017-05-09 | Omeros Corporation | Methods for treating conditions associated with MASP-2 dependent complement activation |
NZ709997A (en) * | 2011-04-08 | 2016-03-31 | Univ Leicester | Methods for treating conditions associated with masp-2 dependent complement activation |
CN107011443B (zh) | 2011-05-04 | 2021-04-30 | 奥默罗斯公司 | 用于抑制masp-2依赖的补体活化的组合物 |
PL2861246T3 (pl) * | 2012-06-18 | 2021-10-25 | Omeros Corporation | Kompozycje i sposoby hamowania MASP-1 i/lub MASP-2 i/lub MASP-3 w leczeniu różnych chorób i zaburzeń |
AU2014229020B2 (en) | 2013-03-15 | 2017-09-28 | Omeros Corporation | Methods of generating bioactive peptide-bearing antibodies and compositions comprising the same |
CA2926385A1 (fr) * | 2013-10-17 | 2015-04-23 | Omeros Corporation | Procedes de traitement d'etats associes a une activation du complement dependant de masp-2 |
KR102564616B1 (ko) | 2016-01-05 | 2023-08-08 | 유니버시티 오브 레스터 | 필요로 하는 대상체에서 섬유증의 억제 방법 |
JOP20170170B1 (ar) | 2016-08-31 | 2022-09-15 | Omeros Corp | صيغ لجسم مضاد تثبيطية لـ masp-2 بتركيز عالي ولزوجة منخفضة وأطقم، وطرق |
US20180105604A1 (en) | 2016-10-13 | 2018-04-19 | University Of Leicester | Methods for reducing proteinuria in a human subject suffering from immunoglobulin a nephropathy |
KR101930345B1 (ko) * | 2016-12-20 | 2019-03-11 | 김은진 | 지혈제 조성물 |
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2017
- 2017-01-05 KR KR1020227001128A patent/KR102564616B1/ko active IP Right Grant
- 2017-01-05 CN CN202311330587.8A patent/CN117503923A/zh active Pending
- 2017-01-05 CN CN201780005761.8A patent/CN108495652A/zh active Pending
- 2017-01-05 CN CN202111548144.7A patent/CN114306593A/zh active Pending
- 2017-01-05 WO PCT/US2017/012345 patent/WO2017120344A1/fr active Application Filing
- 2017-01-05 AU AU2017205453A patent/AU2017205453B2/en active Active
- 2017-01-05 UA UAA201808433A patent/UA127339C2/uk unknown
- 2017-01-05 KR KR1020207027740A patent/KR102475622B1/ko active IP Right Grant
- 2017-01-05 EA EA201891570A patent/EA201891570A1/ru unknown
- 2017-01-05 KR KR1020237017826A patent/KR20230080493A/ko not_active Application Discontinuation
- 2017-01-05 SG SG10202001580SA patent/SG10202001580SA/en unknown
- 2017-01-05 SG SG11201805695SA patent/SG11201805695SA/en unknown
- 2017-01-05 MY MYPI2018001232A patent/MY194810A/en unknown
- 2017-01-05 CA CA3185172A patent/CA3185172A1/fr active Pending
- 2017-01-05 JP JP2018553867A patent/JP6682653B2/ja active Active
- 2017-01-05 US US15/399,524 patent/US10736960B2/en active Active
- 2017-01-05 MA MA043591A patent/MA43591A/fr unknown
- 2017-01-05 CA CA3010593A patent/CA3010593C/fr active Active
- 2017-01-05 KR KR1020187022485A patent/KR102528260B1/ko active IP Right Grant
- 2017-01-05 IL IL294411A patent/IL294411A/en unknown
- 2017-01-05 GE GEAP201714848A patent/GEP20217290B/en unknown
- 2017-01-05 NZ NZ744629A patent/NZ744629A/en unknown
- 2017-01-05 MX MX2018008331A patent/MX2018008331A/es unknown
- 2017-01-05 BR BR112018013723A patent/BR112018013723A2/pt unknown
- 2017-01-05 EP EP17736341.3A patent/EP3400012A4/fr active Pending
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2018
- 2018-07-03 CL CL2018001817A patent/CL2018001817A1/es unknown
- 2018-07-04 IL IL260430A patent/IL260430B2/en unknown
- 2018-07-04 PH PH12018501435A patent/PH12018501435A1/en unknown
- 2018-07-04 MX MX2023007754A patent/MX2023007754A/es unknown
- 2018-07-04 MX MX2024010937A patent/MX2024010937A/es unknown
- 2018-08-03 ZA ZA2018/05238A patent/ZA201805238B/en unknown
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2019
- 2019-05-24 CL CL2019001411A patent/CL2019001411A1/es unknown
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2020
- 2020-03-12 AU AU2020201804A patent/AU2020201804B2/en active Active
- 2020-03-25 JP JP2020053686A patent/JP2020114845A/ja active Pending
- 2020-06-30 US US16/917,157 patent/US12005117B2/en active Active
- 2020-09-23 CL CL2020002444A patent/CL2020002444A1/es unknown
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2022
- 2022-02-22 JP JP2022025226A patent/JP7430208B2/ja active Active
- 2022-06-06 AU AU2022203914A patent/AU2022203914A1/en active Pending
- 2022-08-23 AU AU2022221419A patent/AU2022221419A1/en active Pending
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