[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

MA42273A - Synthèse totale de shishijimicine a et d'analogues de celle-ci - Google Patents

Synthèse totale de shishijimicine a et d'analogues de celle-ci

Info

Publication number
MA42273A
MA42273A MA042273A MA42273A MA42273A MA 42273 A MA42273 A MA 42273A MA 042273 A MA042273 A MA 042273A MA 42273 A MA42273 A MA 42273A MA 42273 A MA42273 A MA 42273A
Authority
MA
Morocco
Prior art keywords
shishijimicin
analogues
total summary
total
Prior art date
Application number
MA042273A
Other languages
English (en)
Inventor
Ruofan Li
Zhaoyong Lu
Kyriacos C Nicolaou
Emmanouil N Pitsinos
Te-Ik Sohn
James Woods
Original Assignee
Univ Rice William M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rice William M filed Critical Univ Rice William M
Publication of MA42273A publication Critical patent/MA42273A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA042273A 2015-06-29 2016-06-29 Synthèse totale de shishijimicine a et d'analogues de celle-ci MA42273A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562186191P 2015-06-29 2015-06-29

Publications (1)

Publication Number Publication Date
MA42273A true MA42273A (fr) 2018-05-02

Family

ID=57609044

Family Applications (1)

Application Number Title Priority Date Filing Date
MA042273A MA42273A (fr) 2015-06-29 2016-06-29 Synthèse totale de shishijimicine a et d'analogues de celle-ci

Country Status (19)

Country Link
US (1) US10590158B2 (fr)
EP (1) EP3313389A1 (fr)
JP (1) JP2018525346A (fr)
KR (1) KR20180053294A (fr)
CN (1) CN108348489A (fr)
AR (1) AR105193A1 (fr)
AU (1) AU2016286071A1 (fr)
BR (1) BR112017028557A2 (fr)
CA (1) CA2990206A1 (fr)
CL (1) CL2017003500A1 (fr)
HK (1) HK1254923A1 (fr)
IL (1) IL256345A (fr)
MA (1) MA42273A (fr)
MX (1) MX2017016885A (fr)
PE (1) PE20180658A1 (fr)
PH (1) PH12018500014A1 (fr)
RU (1) RU2018102808A (fr)
TW (1) TW201713634A (fr)
WO (1) WO2017004172A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110357785B (zh) * 2019-07-26 2020-03-24 东莞市领创环保材料科技有限公司 一种氰酸酯树脂增塑剂的制备方法
CN115197188B (zh) * 2021-04-12 2023-12-26 南开大学 一类具有五环骨架的倍半萜氢醌化合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same
US5261586A (en) * 1992-03-26 1993-11-16 Chen Jen Fu Yarn feeding device with a guiding flange
US5550246A (en) * 1994-09-07 1996-08-27 The Scripps Research Institute Calicheamicin mimics
JP2003238584A (ja) * 2002-02-08 2003-08-27 Yamanouchi Pharmaceut Co Ltd 新規エンジイン化合物
TW200539855A (en) * 2004-03-15 2005-12-16 Wyeth Corp Calicheamicin conjugates
WO2014080251A1 (fr) * 2012-11-24 2014-05-30 Hangzhou Dac Biotech Co., Ltd. Lieurs hydrophiles et leurs utilisations pour la conjugaison de médicaments à des molécules se liant aux cellules

Also Published As

Publication number Publication date
US20180327439A1 (en) 2018-11-15
AU2016286071A8 (en) 2019-08-08
MX2017016885A (es) 2018-09-06
IL256345A (en) 2018-02-28
CN108348489A (zh) 2018-07-31
CL2017003500A1 (es) 2018-04-27
RU2018102808A3 (fr) 2020-04-30
TW201713634A (zh) 2017-04-16
AR105193A1 (es) 2017-09-13
WO2017004172A1 (fr) 2017-01-05
EP3313389A1 (fr) 2018-05-02
KR20180053294A (ko) 2018-05-21
AU2016286071A1 (en) 2018-02-01
RU2018102808A (ru) 2019-07-30
JP2018525346A (ja) 2018-09-06
BR112017028557A2 (pt) 2018-09-04
PH12018500014A1 (en) 2018-07-09
PE20180658A1 (es) 2018-04-17
US10590158B2 (en) 2020-03-17
WO2017004172A8 (fr) 2018-01-11
CA2990206A1 (fr) 2017-01-05
HK1254923A1 (zh) 2019-08-02

Similar Documents

Publication Publication Date Title
IL290154B1 (en) Benzopyrazole compounds and their analogs
MA42036A (fr) Analogues nucléosidiques 5'-substitués
MA46180A (fr) Analogues de l'amyline
MA49715A (fr) Oligomères et conjugués d'oligomères
FR3019522B1 (fr) Ensemble sustentateur amovible d'un giravion et giravion
FR3021535B1 (fr) Utilisation cosmetique d'un polysaccharide sulfate
IL264403A (en) Vortioxetine analogue and use and preparation thereof
MA44491A (fr) Prothèse totale de poignet et procédés associés
MA42273A (fr) Synthèse totale de shishijimicine a et d'analogues de celle-ci
MA42130A (fr) Combinaisons d'opioïdes et de n-acyléthanolamines
ZA201908264B (en) Formulations of homotaurines and salts thereof
GB201720188D0 (en) Analogues of PYY
MA41216A (fr) Synthèse totale de trioxacarcine dc-45-a2 et préparation d'analogues de trioxacarcine
UA33118S (uk) Підвіска «коловрат із зіркою русі»
UA33117S (uk) Підвіска «коловрат свєточ»
UA34199S (uk) Підвіска «громовник»
UA31424S (uk) Підвісок «зміст віри»
UA35842S (uk) Конструкція «полконайзер» для створення стелажів
UA34698S (uk) Ювелірна прикраса «хлопчик-пряник»
UA34203S (uk) Підвіска «зігфрід»
UA31415S (uk) Підвісок «радість віри»
UA31871S (uk) Інтер'єр закладу зберігання «s-trans»
UA31659S (uk) Підвісок «промінь віри»
UA31441S (uk) Підвісок «вінець віри»
UA31432S (uk) Підвісок «корона віри»