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MA27157A1 - Methode de traitement d'affections osseuses. - Google Patents

Methode de traitement d'affections osseuses.

Info

Publication number
MA27157A1
MA27157A1 MA27736A MA27736A MA27157A1 MA 27157 A1 MA27157 A1 MA 27157A1 MA 27736 A MA27736 A MA 27736A MA 27736 A MA27736 A MA 27736A MA 27157 A1 MA27157 A1 MA 27157A1
Authority
MA
Morocco
Prior art keywords
treatment
bone conditions
risedronate
polymorph
solvate
Prior art date
Application number
MA27736A
Other languages
English (en)
Inventor
Pamela Jean Schofield
David Ernest Burgio
Den Berg Henry Van
Arkadi Aaron Chines
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23352430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA27157(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MA27157A1 publication Critical patent/MA27157A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MA27736A 2001-12-21 2004-06-15 Methode de traitement d'affections osseuses. MA27157A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34487501P 2001-12-21 2001-12-21

Publications (1)

Publication Number Publication Date
MA27157A1 true MA27157A1 (fr) 2005-01-03

Family

ID=23352430

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27736A MA27157A1 (fr) 2001-12-21 2004-06-15 Methode de traitement d'affections osseuses.

Country Status (24)

Country Link
US (5) US20030118634A1 (fr)
EP (1) EP1455796A1 (fr)
JP (1) JP2005514400A (fr)
KR (1) KR100638122B1 (fr)
CN (1) CN100479823C (fr)
AR (1) AR038041A1 (fr)
AU (1) AU2002360619B2 (fr)
CA (1) CA2469779C (fr)
CZ (1) CZ2004690A3 (fr)
HK (1) HK1087039A1 (fr)
HU (1) HUP0402267A3 (fr)
IL (2) IL162053A0 (fr)
MA (1) MA27157A1 (fr)
MX (1) MXPA04006027A (fr)
MY (1) MY147886A (fr)
NO (1) NO340249B1 (fr)
NZ (1) NZ532994A (fr)
PE (1) PE20030743A1 (fr)
PL (1) PL371264A1 (fr)
RU (1) RU2294203C2 (fr)
SK (1) SK2532004A3 (fr)
TW (1) TWI349553B (fr)
WO (1) WO2003055496A1 (fr)
ZA (1) ZA200404007B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2469779C (fr) * 2001-12-21 2008-02-12 The Procter & Gamble Company Methode de traitement d'affections osseuses
CN100551377C (zh) * 2002-05-10 2009-10-21 弗·哈夫曼-拉罗切有限公司 用于治疗和预防骨质疏松症的二膦酸
US20040097468A1 (en) * 2002-11-20 2004-05-20 Wimalawansa Sunil J. Method of treating osteoporosis and other bone disorders with upfront loading of bisphosphonates, and kits for such treatment
PL212072B1 (pl) * 2002-12-20 2012-08-31 Hoffmann La Roche Tabletka zawierająca jako substancję czynną do 250 mg kwasu ibandronowego oraz sposób jej wytwarzania
ES2921141T3 (es) * 2004-05-24 2022-08-18 Theramex Hq Uk Ltd Forma farmacéutica oral sólida entérica de un bisfosfonato que contiene un agente quelante
WO2006020009A1 (fr) * 2004-07-23 2006-02-23 The Procter & Gamble Company Dosage oral solide formant un bisphosphonate et contenant un agent chélateur
US20070191315A1 (en) * 2006-02-16 2007-08-16 Bengt Bergstrom Method for administering ibandronate

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA777769A (en) * 1963-03-18 1968-02-06 H. Roy Clarence Substituted methylene diphosphonic acid compounds and detergent compositions
DE2405254C2 (de) * 1974-02-04 1982-05-27 Henkel KGaA, 4000 Düsseldorf Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper
DE2534391C2 (de) * 1975-08-01 1983-01-13 Henkel KGaA, 4000 Düsseldorf 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren
DE2745083C2 (de) * 1977-10-07 1985-05-02 Henkel KGaA, 4000 Düsseldorf Hydroxydiphosphonsäuren und Verfahren zu deren Herstellung
US4252742A (en) * 1979-07-13 1981-02-24 Ciba-Geigy Corporation Chemical process for the preparation of 2,6-dialkylcyclohexylamines from 2,6-dialkylphenols
DE2943498C2 (de) * 1979-10-27 1983-01-27 Henkel KGaA, 4000 Düsseldorf Verfahren zur Herstellung von 3-Amino-1-hydroxypropan-1,1-diphosphonsäure
DE3016289A1 (de) * 1980-04-28 1981-10-29 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
FR2531088B1 (fr) * 1982-07-29 1987-08-28 Sanofi Sa Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation
DE3434667A1 (de) * 1984-09-21 1986-04-03 Henkel KGaA, 4000 Düsseldorf 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung
IT1196315B (it) * 1984-10-29 1988-11-16 Gentili Ist Spa Procedimento per la preparazione di acidi difosfonici
IL77243A (en) * 1984-12-21 1996-11-14 Procter & Gamble Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds
US4812311A (en) * 1984-12-21 1989-03-14 The Procter & Gamble Company Kit for use in the treatment of osteoporosis
DE3512536A1 (de) * 1985-04-06 1986-10-16 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeure-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4761406A (en) * 1985-06-06 1988-08-02 The Procter & Gamble Company Regimen for treating osteoporosis
DE3540150A1 (de) * 1985-11-13 1987-05-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3626058A1 (de) * 1986-08-01 1988-02-11 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE3640938A1 (de) * 1986-11-29 1988-06-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindung enthaltende arzneimittel
CA1339805C (fr) * 1988-01-20 1998-04-07 Yasuo Isomura Acide (cycloalkylamino) methylenebis phosphonique et medicaments le contenant comme ingredients actif
EP0333082A3 (fr) * 1988-03-15 1991-05-02 Takeda Chemical Industries, Ltd. Composés céphem, leur préparation et application
CA1336328C (fr) * 1988-04-11 1995-07-18 Walter G. Leonard Methode pour augmenter la densite osseuse chez l'etre humain
DE3822650A1 (de) * 1988-07-05 1990-02-01 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US5018651A (en) * 1988-12-27 1991-05-28 Hull Harold L Side or end dump article carrier
DE3917153A1 (de) * 1989-05-26 1990-11-29 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
NL8902727A (nl) * 1989-11-06 1991-06-03 Philips Nv Objecthouder voor ondersteuning van een object in een geladen deeltjesbundelsysteem.
US5356887A (en) * 1990-01-31 1994-10-18 Merck & Co., Inc. Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids
US5019651A (en) * 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof
TW237386B (fr) * 1992-04-15 1995-01-01 Ciba Geigy
US5391743A (en) * 1992-05-29 1995-02-21 Procter & Gamble Pharmaceuticals, Inc. Quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism and methods of treating and preventing dental calculus and plaque
RU2126414C1 (ru) * 1992-05-29 1999-02-20 Дзе Проктер энд Гэмбл Фармасьютикалз, Инк. Содержащие четвертичный азот фосфонаты для лечения анормального кальциевого и фосфатного метаболизма, а также профилактики и лечения зубных налетов и зубных камней, фармацевтические композиции и способ лечения
SK160994A3 (en) * 1992-06-30 1996-01-10 Procter & Gamble Pharma Compositions for the treatment of arthritis containing phosphonates and nsaid
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
FR2703590B1 (fr) * 1993-04-05 1995-06-30 Sanofi Elf Utilisation de derives d'acide bisphosphonique pour la preparation de medicaments destines a favoriser la reparation osseuse .
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
US20010007863A1 (en) * 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
US6008206A (en) * 1994-09-21 1999-12-28 Merck & Co., Inc. Sodium alendronate preparation for local administration
US20010051616A1 (en) * 1995-02-17 2001-12-13 David B. Karpf Method of lessening the risk of vertebral fractures
AU733637B2 (en) * 1995-06-07 2001-05-17 Co.Don Ag Standardized, primary osteoblast cell cultures from osteoporotic patients and their use in the diagnosis of osteoporosis and in testing potential osteoporosis therapeutic agents
DE19615812A1 (de) * 1996-04-20 1997-10-23 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
GB2324726A (en) * 1997-05-01 1998-11-04 Merck & Co Inc Combination Therapy for the Treatment of Osteoporosis
US6432932B1 (en) * 1997-07-22 2002-08-13 Merck & Co., Inc. Method for inhibiting bone resorption
US5994329A (en) * 1997-07-22 1999-11-30 Merck & Co., Inc. Method for inhibiting bone resorption
US6124314A (en) * 1997-10-10 2000-09-26 Pfizer Inc. Osteoporosis compounds
US6432931B1 (en) * 1998-06-24 2002-08-13 Merck & Co., Inc. Compositions and methods for inhibiting bone resorption
IT1303672B1 (it) * 1998-07-28 2001-02-23 Nicox Sa Sali nitrati di farmaci attivi nei disordini ossei
EP0998933A1 (fr) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Procédé pour la préparation de compositions pharmaucetiques contenant des diphosphonates pour administration orale
EP0998932A1 (fr) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Forme d'administration pharmaceutique contenant des diphosphonates ou leurs sels et méthode pour la fabriquer
DE69927048T2 (de) * 1998-12-04 2006-06-08 Roche Diagnostics Gmbh Ibandroinsäure zur förderung der osseointegration der endoprothesen
US6468559B1 (en) * 2000-04-28 2002-10-22 Lipocine, Inc. Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods
CN1224423C (zh) * 2000-07-17 2005-10-26 山之内制药株式会社 改善口服吸收的医药组合物
JP2004504351A (ja) * 2000-07-19 2004-02-12 イーライ・リリー・アンド・カンパニー 骨量増加の増強方法
US6638920B2 (en) * 2000-07-21 2003-10-28 Merck & Co., Inc. Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses
JP2004519463A (ja) * 2001-01-23 2004-07-02 ガドール エス アー 骨の代謝病の予防および／または治療のための組成物、その組成物の調製方法およびその使用
AR034199A1 (es) * 2001-02-01 2004-02-04 Riderway Corp Composicion farmacologica liquida para el tratamiento de enfermedades oseas y procedimientos para su elaboracion
ATE496624T1 (de) * 2001-02-06 2011-02-15 Sydney Children S Hospitals Network Randwick And Westmead Incorporating The Royal Alexandra Hospital Arzneimittel zur behandlung von osteonekrose und zur versorgung von patienten mit risiko für die entstehung von osteonekrose
US7309698B2 (en) * 2001-03-01 2007-12-18 Emisphere Technologies, Inc. Compositions for delivering bisphosphonates
WO2002091993A2 (fr) * 2001-05-10 2002-11-21 Merck & Co., Inc. Modulateurs des recepteurs des oestrogenes
US20030139378A1 (en) * 2001-12-13 2003-07-24 Daifotis Anastasia G. Liquid bisphosphonate formulations for bone disorders
US20050070504A1 (en) * 2001-12-21 2005-03-31 The Procter & Gamble Co. Risedronate compositions and their methods of use
CA2469779C (fr) * 2001-12-21 2008-02-12 The Procter & Gamble Company Methode de traitement d'affections osseuses
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
CA2480814A1 (fr) * 2002-04-05 2003-10-23 Merck & Co., Inc. Procede d'inhibition de resorption osseuse a l'aide d'une formulation a base d'alendronate et de vitamine d
CN100551377C (zh) * 2002-05-10 2009-10-21 弗·哈夫曼-拉罗切有限公司 用于治疗和预防骨质疏松症的二膦酸
US20040188316A1 (en) * 2003-03-26 2004-09-30 The Procter & Gamble Company Kit for pharmaceutical use

Also Published As

Publication number Publication date
NO340249B1 (no) 2017-03-27
US20080260827A1 (en) 2008-10-23
PL371264A1 (en) 2005-06-13
EP1455796A1 (fr) 2004-09-15
HK1087039A1 (en) 2006-10-06
KR20040065283A (ko) 2004-07-21
US20080214505A1 (en) 2008-09-04
ZA200404007B (en) 2005-07-27
PE20030743A1 (es) 2003-10-22
WO2003055496A1 (fr) 2003-07-10
KR100638122B1 (ko) 2006-10-24
TW200301704A (en) 2003-07-16
HUP0402267A3 (en) 2007-05-29
RU2294203C2 (ru) 2007-02-27
MY147886A (en) 2013-01-31
TWI349553B (en) 2011-10-01
IL162053A (en) 2009-09-22
CA2469779A1 (fr) 2003-07-10
CZ2004690A3 (cs) 2004-09-15
IL162053A0 (en) 2005-11-20
US20030118634A1 (en) 2003-06-26
US20070166237A1 (en) 2007-07-19
AR038041A1 (es) 2004-12-22
CN1723024A (zh) 2006-01-18
NO20043113L (no) 2004-09-01
RU2004122433A (ru) 2005-03-10
MXPA04006027A (es) 2004-09-27
CN100479823C (zh) 2009-04-22
CA2469779C (fr) 2008-02-12
AU2002360619A1 (en) 2003-07-15
SK2532004A3 (en) 2004-11-03
US20080261924A1 (en) 2008-10-23
AU2002360619B2 (en) 2006-10-05
JP2005514400A (ja) 2005-05-19
NZ532994A (en) 2008-05-30
HUP0402267A2 (hu) 2005-02-28

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