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KLEHR et al., 1987 - Google Patents

Formation of 4-Ethoxy-4'-nitrosodiphenylamine in the Reaction of the Phenacetin Metabolite 4-Nitrosophenetol with Glutathione

KLEHR et al., 1987

Document ID
365408117515719210
Author
KLEHR H
EYER P
SCHÄFER W
Publication year

External Links

Snippet

Phenacetin, a constituent of several analgesic and antipyretic formulations has been made responsible for a variety of toxic and carcinogenic actions. 4-Nitrosophenetol, the N- oxydation product of intermediate 4-phenetidine, forms methemoglobin and binds covalently …
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

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